|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | On the tuning of electrical and thermal transport in thermoelectrics: an integrated theory–experiment perspective显示文摘During the last two decades,we have witnessed great progress in research on thermoelectrics.There are two primary focuses.One is the fundamental understanding of electrical and thermal transport,enabled by the interplay of theory and experiment;the other is the substantial enhancement of the performance of various thermoelectric materials,through synergistic optimisation of those intercorrelated transport parameters.Here we review some of the successful strategies for tuning electrical and thermal transport.For electrical transport,we start from the classical but still very active strategy of tuning band degeneracy(or band convergence),then discuss the engineering of carrier scattering,and finally address the concept of conduction channels and conductive networks that emerge in complex thermoelectric materials.For thermal transport,we summarise the approaches for studying thermal transport based on phonon–phonon interactions valid for conventional solids,as well as some quantitative efforts for nanostructures.We also discuss the thermal transport in complex materials with chemical-bond hierarchy,in which a portion of the atoms(or subunits)are weakly bonded to the rest of the structure,leading to an intrinsic manifestation of part-crystalline part-liquid state at elevated temperatures.In this review,we provide a summary of achievements made in recent studies of thermoelectric transport properties,and demonstrate how they have led to improvements in thermoelectric performance by the integration of modern theory and experiment,and point out some challenges and possible directions. | Jiong Yang Lili Xi Wujie Qiu Lihua Wu Xun Shi Lidong Chen Jihui Yang Wenqing Zhang Ctirad Uher David J Singh | 2016 | npj Computational Materials2016，，1： | 24 |
| 2 | The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation显示文摘最近的研究在 PHF8 识别了变化,编码 JmjC 的 X 连接基因包含域的蛋白质,为 X 连接智力迟钝(XLMR ) 的一个原因的因素并且劈开 lip/cleft 腭。然而,内在的机制是未知的。这里,我们证明 PHF8 为 retinoic 酸受体(RAR ) 是 histone demethylase 和激活剂。尽管为 H3K4me3/2/1 和 H3K9me2/1 demethylation 的活动在细胞底的试金被检测, recombinant PHF8 在 vitro 展出了仅仅 H3K9me2/1 demethylase 活动,建议 PHF8 是其特性可以在 vivo 被调制的 H3K9me2/1 demethylase。重要地,在 XLMR 病人识别的变异的 PHF8 (在到丝氨酸的位置 279 点的本氨基丙酸) 在酶的活动是有缺点的,显示 histone demethylase 活动的损失有原因地与疾病的发作被连接。另外,我们证明 PHF8 经由一个 N 终端哲学博士手指领域明确地绑在 H3K4me3/2 肽。与为在 neuronal 区别的 PHF8 的一个角色一致,在鼠标的 PHF8 击倒胚胎的癌 P19 房间损害导致 RA 的 neuronal 区别,而 overexpression 野类型然而并非向 neuronal 区别的 F279S 变异的 PHF8 驱动器 P19 房间。而且,我们证明 PHF8 为 RAR 伪作为激活剂与 RAR 伪和功能交往。一起拿,我们的结果建议 PHF8 调制的 histone methylation 在 neuronal 区别起一个关键作用。 | Jihui Qiu Guang Shi Yuanhui Jia Jing Li Meng Wu Jiwen Li Shuo Dong Jiemin Wong | 2010 | Cell Research2010，20，8： | 16 |
| 3 | Structure of the YTH domain of human YTHDF2 in complex with an m6A mononucleotide reveals an aromatic cage for m6A recognition显示文摘 | Fudong Li Debiao Zhao Jihui Wu Yunyu Shi | 2014 | Cell Research2014，24，12： | 16 |
| 4 | Artificial intelligence in drug design显示文摘Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology,the computer-aided drug design techniques have been successfully applied in almost every stage of the drug discovery and development pipeline to speed up the process of research and reduce the cost and risk related to preclinical and clinical trials.Owing to the development of machine learning theory and the accumulation of pharmacological data, the artificial intelligence(AI) technology, as a powerful data mining tool, has cut a figure in various fields of the drug design, such as virtual screening,activity scoring, quantitative structure-activity relationship(QSAR) analysis, de novo drug design, and in silico evaluation of absorption, distribution, metabolism, excretion and toxicity(ADME/T) properties. Although it is still challenging to provide a physical explanation of the AI-based models, it indeed has been acting as a great power to help manipulating the drug discovery through the versatile frameworks. Recently, due to the strong generalization ability and powerful feature extraction capability,deep learning methods have been employed in predicting the molecular properties as well as generating the desired molecules,which will further promote the application of AI technologies in the field of drug design. | Feisheng Zhong Jing Xing Xutong Li Xiaohong Liu Zunyun Fu Zhaoping Xiong Dong Lu Xiaolong Wu Jihui Zhao Xiaoqin Tan Fei Li Xiaomin Luo Zhaojun Li Kaixian Chen Mingyue Zheng Hualiang Jiang | 2018 | Science China(Life Sciences)2018，61，10： | 10 |
| 5 | Review-material degradation assessed by digital image processing:Fundamentals,progresses,and challenges显示文摘Material degradation is accompanied by the changes in surface structure,morphology,and composition.These changes can be recorded by a variety of image acquisition devices that export digital images in grayscale or true color to a detector.Information regarding corrosion type and extent can be extracted with image processing methods.This paper provides a comprehensive review of material degradation assessed by digital image processing.Digital image processing systems used to assess material degradation are briefly reviewed,and the algorithms developed to process metallic materials degradation images are described.Physical and electrochemical methods that can be used to support digital image processing results are summarized,and future work that will augment the present methods of evaluating material degradation are discussed. | Da-Hai Xia Shizhe Song Lei Tao Zhenbo Qin Zhong Wu Zhiming Gao Jihui Wang Wenbin Hu Yashar Behnamian Jing-Li Luo | 2020 | Journal of Materials Science & Technology2020，52，18： | 8 |
| 6 | Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation显示文摘在房间期间,分割要求忠诚有丝分裂的锭子汇编和染色体分离的基因信息的稳定的传播。运用了 GTPase 戏在有丝分裂的锭子汇编的一个关键角色。然而,在锭子的 Ran-GTP 的一个化学坡度的产生怎么被联合到有丝分裂的 translational 以后修正,从来没被描绘过。这里,我们解决了复杂结构与核苷酸版本因素 Mog1 跑了并且描出一个新奇有丝分裂特定的调整 acetylation 的 Ran-Mog1 相互作用在染色体分离期间。我们的指导结构的功能的分析表明那 Mog1 与 RCC1 竞争为以一种 GTP/GDP-dependent 方式变有约束力。生物化学的描述表明了那 Mog1 固定跑阻止 RCC1 有约束力、随后的 GTP 装载。令人惊讶地,跑了是 TIP60 的真正的底层,并且由 TIP60 的 Lys134 的 acetylation 解放 Mog1 从在有丝分裂期间变有约束力。重要地,这个得到 acetylation 的开关对 RCC1 变有约束力支持 Ran-GTP 的高水平,它为染色体排列是必要的。这些结果建立一以前 TIP60 由调节在提供 Ran-GTP 水平的 homeostatic 控制的规章的机制运用了的 uncharacterized 为在有丝分裂的染色体分离的受动器绑定。 | Xiaoling Bao Heng Liu Xing Liu Ke Ruan Yonshui Zhang Zhiyong Zhang Qi Hu Ying Liu Saima Akram Jiahai Zhang Qingguo Gong Wenwen wang Xiao Yuan Jian-Li Lingli Zhao Zhen Dou Ruijun Tian Xuebiao Yao Jihui Wu Yunyu Shi | 2018 | Journal of Molecular Cell Biology2018，10，1： | 8 |
| 7 | Distribution Characteristics and Influencing Factors of Geological Hazards in Tibet显示文摘Tibet is one of the areas with most serious geological hazards in China, and the distribution of disasters has obvious local characteristics. Tibet can be classified as three parts through zoning the danger degree, the mountain canyon high danger zone of east and southeast Tibet, the plateau mountain lake basin and valley middle danger zone of south Tibet , and the Plateau Mountain lake basin low danger zone of south Tibet. This paper takes the debris flow, collapse, landslide as the key points to analyze the distribution characteristics of geological hazards, and analyze the factors which influence the distribution of geological hazards, such as terrain landform, formation lithology, geologic structure pattern, precipitation, earthquake, human activity and so on. finally, as a conclusion: in whole Tibet, the geological hazards are more in southeast than in northwest, more in mountainous area which in the edge of plateau and river valley than in the interior of plateau and lake basin. And most hazards distribute in the regions where human activity is stronger than in other regions, for example towns or strips along the highway. | FAN Jihui WU Caiyan Cheng Genwei | 2006 | Wuhan University Journal of Natural Sciences2006，11，4： | 5 |
| 8 | Efficacy of moxibustion by stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) on hyperplasia of mammary gland in rats显示文摘OBJECTIVE: To evaluate the efficacy of moxibustion, through stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) in rats with hyperplasia of mammary gland(HMG) which induced by estrogen and progestogen.METHODS: Thirty female Sprague-Dawley rats were randomly divided into saline control group,HMG model group, and HMG moxibustion group with 10 in each group. Saline control was the group injected by saline. HMG model were created by injection of estrogen and progestogen. Moxibustion group was also injected of estrogen and progesto-gen with moxibustion at the same time. The Changes of nipple diameter and height were measured.The rats' skin temperature was recorded by an infrared thermal camera at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). Pathological changes of mammary gland in rats were also observed under light microscope.RESULTS: The diameter and height of the nipples in model group were prominently bigger and higher than that in control group(P < 0.01). The diameter and height in moxibustion group were prominently smaller and lower than that in model group(P < 0.01), and there was no significant difference between moxibustion group and control group.Compared with control group, skin temperature of the nipples, mammary area, and acupoints Danzhong(CV 17) and Ganshu(BL 18) decreased prominently in model group(P < 0.01-0.05). Compared with model group, skin temperature of that in moxibustion group increased prominently(P <0.05).CONCLUSION: Treatment with moxibustion can effectively decrease the HMG rats' nipple diameter and height, and increase the skin temperature in HMG model rats at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). This study convinces the therapeutic effect of moxibustion on mammary gland hyperplasia. | Yang Jiamin Wu Jihui Shen Xiaoyu Zhang Mei Liu Zhenzhen Qi Dandan Zhou Jin Cui Xiao Zhang Lufen Li Yuhang | 2018 | Journal of Traditional Chinese Medicine2018，38，1： | 3 |
| 9 | Nitrogen-rich carbon spheres made by a continuous spraying process for high-performance supercapacitors显示文摘Supercapacitors 有高力量密度,高效率,和长骑车一生;然而,启用他们的更宽的使用,他们的精力密度必须显著地被改进。有更好的电容,率表演,和骑车的稳定性的改进的碳材料的设计和合成作为 supercapacitor 研究的主要主题出现了。此处,我们报导一个灵巧的合成方法基于一个连续喷洒喷雾器的过程准备充满氮的碳粒子。有高表面区域的方法收益粒子,一致多微孔的结构,并且是高度做 N 的,导致在水、商业的器官的电解质为使用与高精力和力量密度启用 supercapacitors 的构造的协同。而且,我们使用了密度证明改进性能由于提高的 wettability,在碳 / 电解质的离子吸附相互作用连接那的功能的理论计算源于氮做。这些调查结果提供新卓见进在碳材料的电容改进做的 heteroatom 的角色;另外,我们的方法为做的碳的大规模生产提供一条有效线路。 | Fei Sun Haobin Wu Xin Liu Fang Liu Huihui zhou Jihui Gao Yunfeng Lu | 2016 | Nano Research2016，9，11： | 2 |
| 10 | Solution structure of BmPO2, a new potassium channel blocker form the venom of the Chinese Scorpion Buthus martensi Karsch显示文摘 | Xu Yingqi Wu Jihui Pei Jiming | 2000 | Biochemistry2000，39，： | 1 |
| 11 | Solution structure and DNA-binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor 显示文摘 | Yang Wulin Xu Yinqi Wu Jihui | 2003 | Biochemistry2003，42，： | 1 |
| 12 | Identification of a dominant murine T-cell epitope in recombinant protein P29 from Echinococcus granulosus显示文摘Echinococcus granulosus causes echinococcosis,an important zoonotic disease worldwide and a major public health issue.Vaccination is an economical and practical approach for controlling E.granulosus.We have previously revealed that a recombinant protein P29(rEg.P29)is a good vaccine candidate against E.granulosus.However,T cell immunogenic epitopes have not been identified.In the present study,we use rEg.P29-immunized mice as models to screen immunogenic epitopes for the construction of a novel multi-epitope vaccine.We search for immunodominant epitopes from an overlapping peptide library to screen the peptides of rEg.P29.Our results confirm that rEg.P29 immunization in mice elicits the activation of T cells and induces cellular immune responses.Further analyses show that a T cell epitope within amino acids 86–100 of rEg.P29 elicits significant antigen-specific IFN-γproduction in CD4^(+) and CD8^(+) T cells and promotes specific T-cell activation and proliferation.Collectively,these results provide a reference for the construction of a novel vaccine against broad E.granulosus genotypes based on epitopes of rEg.P29. | Yongxue Lv Yazhou Zhu Liangliang Chang Jihui Yang Yinqi Zhao Jiaqing Zhao Yana Wang Mingxing Zhu Changyou Wu Wei Zhao | 2022 | Acta Biochimica et Biophysica Sinica2022，54，4： | 1 |
| 13 | Boundary of sets in pansystems information system显示文摘 | JiHui Zhang Chuan Li Xuemou Wu | 1997 | Kybernetes :The International Journal of Systems and Cybernetics1997，26，45： | 1 |
| 14 | Structural basis of protein-protein interaction studied by NMR显示文摘 | Shi Yunyu Wu Jihui | 2007 | Journal of Structural and Functional Genomics2007，8，： | 1 |
| 15 | Interactions between mercury and dry FGD ash in simulated post combustion conditions 显示文摘 | WU Shaohua WANG Shuai GAO Jihui | 2011 | Journal of Hazardous Materials2011，188，： | 1 |
| 16 | Backbone and side chain assignments of human Peptidylprolyl isomerase Like 1 ( hPPIL1 ) 显示文摘 | Xu Chao Wu Jihui Xu Yingqi | 2005 | Journal of Biomolecular NMR2005，31，2： | 1 |
| 17 | Interactions between mercury and dry FGD ash in simulated post combustion conditions显示文摘 | Wu Shaohua Wang Shuai Gao Jihui | 2011 | Journal of Hazardous Materials2011，188，： | 1 |
| 18 | Guidelines for the diagnosis and treatment of acute pancreatitis in China (2021)显示文摘Acute pancreatitis(AP)is a common acute abdominal condition of the digestive system.In recent years,treatment concepts,methods,and strategies for the diagnosis of AP have advanced,and this has played an important role in promoting the standardization of AP diagnosis and treatment and improving the treatment quality of AP patients.On the basis of previous guidelines and expert consensus,this guideline adopts an evidence-based,problem-based expression;synthesizes important clinical research data at home and abroad in the most recent 5 years;and forms 29 recommendations through multidisciplinary expert discussion,including diagnosis,treatment,and follow-up.It is expected to provide evidence support for the treatment of AP in the clinical setting in China. | Fei Li Shouwang Cai Feng Cao Rufu Chen Deliang Fu Chunlin Ge Chunyi Hao Jihui Hao Heguang Huang Zhixiang Jian Gang Jin Ang Li Haimin Li Shengping Li Weiqin Li Yixiong Li Tingbo Liang Xubao Liu Wenhui Lou Yi Miao Yiping Mou Chenghong Peng Renyi Qin Chenghao Shao Bei Sun Guang Tan Xiaodong Tian Huaizhi Wang Lei Wang Wei Wang Weilin Wang Junmin Wei Heshui Wu Wenming Wu Zheng Wu Changqing Yan Yinmo Yang Xiaoyu Yin Xianjun Yu Chunhui Yuan Taiping Zhang Yupei Zhao on behalf of the Chinese Pancreatic Surgery Association | 2021 | Journal of Pancreatology2021，4，2： | 1 |
| 19 | A polysaccharide fraction of adlay seed ( Coix lachryma - jobi L.) induces apoptosis in human non-small cell lung cancer A549 cells显示文摘 | Xiangyi Lu Wei Liu Junhua Wu Mengxian Li Juncheng Wang Jihui Wu Cheng Luo | 2012 | Biochemical and Biophysical Research Communications2012，，： | 1 |
| 20 | Solution structure of a fragment of the dimerization domain of DP-1 determined by 1 H-nuclear magnetic resonance and distance geometry显示文摘 | Shouhong Guang Jihui Wu Tianning Yu Youlin Xia Yunyu Shi | 1998 | Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology1998，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员