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| 1 | Research Progress in Laser Active Debris Removal of CAST显示文摘Based on the introduction to theresearch status and trend of international space-based laser debris re-moval technology, the existing problems of space-based laser debris removal technology are systematically analyzed.In view of the existing problems, the work and research progress of the Beijing Institute of Spacecraft EnvironmentEngineering in this field are introduced from several aspects, such as dynamic behavior of laser-driven debris, orbittransfer model, ground simulation system, space-based removal system scheme and target selection strategy. The mainresearch methods include laser-driven micro-impulse measurement experiment, surface triangulation three-dimension-al reconstruction calculation method based on laser-material interaction theory, simulation calculation based on orbitaldynamics, etc. It also looks forward to the future research direction in the field of this technology. | CHEN Chuan YANG Wulin GONG Zizheng LI Ming | 2018 | Aerospace China2018，19，4： | 3 |
| 2 | Augmented Virtual Stiffness Rendering of a Cable-driven SEA for Human-Robot Interaction显示文摘Human-robot interaction(HRI) is fundamental for human-centered robotics, and has been attracting intensive research for more than a decade. The series elastic actuator(SEA) provides inherent compliance, safety and further benefits for HRI, but the introduced elastic element also brings control difficulties. In this paper, we address the stiffness rendering problem for a cable-driven SEA system, to achieve either low stiffness for good transparency or high stiffness bigger than the physical spring constant, and to assess the rendering accuracy with quantified metrics. By taking a velocity-sourced model of the motor, a cascaded velocity-torque-impedance control structure is established. To achieve high fidelity torque control, the 2-DOF(degree of freedom) stabilizing control method together with a compensator has been used to handle the competing requirements on tracking performance, noise and disturbance rejection,and energy optimization in the cable-driven SEA system. The conventional passivity requirement for HRI usually leads to a conservative design of the impedance controller, and the rendered stiffness cannot go higher than the physical spring constant. By adding a phase-lead compensator into the impedance controller,the stiffness rendering capability was augmented with guaranteed relaxed passivity. Extensive simulations and experiments have been performed, and the virtual stiffness has been rendered in the extended range of 0.1 to 2.0 times of the physical spring constant with guaranteed relaxed passivity for physical humanrobot interaction below 5 Hz. Quantified metrics also verified good rendering accuracy. | Ningbo Yu Wulin Zou Wen Tan Zhuo Yang | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，4： | 2 |
| 3 | Nanofiltration for drinking water treatment: a review显示文摘In recent decades,nanofiltration(NF)is considered as a promising separation technique to produce drinking water from different types of water source.In this paper,we comprehensively reviewed the progress of NFbased drinking water treatment,through summarizing the development of materials/fabrication and applications of NF membranes in various scenarios including surface water treatment,groundwater treatment,water reuse,brackish water treatment,and point of use applications.We not only summarized the removal of target major pollutants(e.g.,hardness,pathogen,and natural organic matter),but also paid attention to the removal of micropollutants of major concern(e.g.,disinfection byproducts,per-and polyfluoroalkyl substances,and arsenic).We highlighted that,for different applications,fit-for-purpose design is needed to improve the separation capability for target compounds of NF membranes in addition to their removal of salts.Outlook and perspectives on membrane fouling control,chlorine resistance,integrity,and selectivity are also discussed to provide potential insights for future development of high-efficiency NF membranes for stable and reliable drinking water treatment. | Hao Guo Xianhui Li Wulin Yang Zhikan Yao Ying Mei Lu Elfa Peng Zhe Yang Senlin Shao Chuyang Y.Tang | 2022 | Frontiers of Chemical Science and Engineering2022，16，5： | 1 |
| 4 | Synthesis and characterization of polyimide from metal-containing ( Ba, Sr, Pb, Zn) diamines :显示文摘 | Zeng Wenxiang Qiu Wulin Yang Xuejie | 1995 | Polymer1995，36，19： | 1 |
| 5 | Solution structure and DNA-binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor 显示文摘 | Yang Wulin Xu Yinqi Wu Jihui | 2003 | Biochemistry2003，42，： | 1 |
| 6 | Corrosion resistance of sintered NdFeB magnets with various surface coating显示文摘 | Chen E Peng K Yang Wulin | 2014 | Applied'' Mechanics and Materials2014，492，： | 1 |
| 7 | Cathodic biofouling control by microbial separators in air-breathing microbial fuel cells显示文摘Microbial fuel cells(MFCs)incorporating air-breathing cathodes have emerged as a promising ecofriendly wastewater treatment technology capable of operating on an energy-free basis.However,the inevitable biofouling of these devices rapidly decreases cathodic catalytic activity and also reduces the stability of MFCs during long-term operation.The present work developed a novel microbial separator for use in air-breathing MFCs that protects cathodic catalytic activity.In these modified devices,microbes preferentially grow on the microbial separator rather than the cathodic surface such that biofouling is prevented.Trials showed that this concept provided low charge transfer and mass diffusion resistance values during the cathodic oxygen reduction reaction of 4.6±1.3 and 17.3±6.8 U,respectively,after prolonged operation.The maximum power density was found to be stable at 1.06±0.07 W m2 throughout a long-term test and the chemical oxygen demand removal efficiency was increased to 92%compared with a value of 83%for MFCs exhibiting serious biofouling.In addition,a cathode combined with a microbial separator demonstrated less cross-cathode diffusion of oxygen to the anolyte.This effect indirectly induced the growth of electroactive bacteria and produced higher currents in air-breathing MFCs.Most importantly,the present microbial separator concept enhances both the lifespan and economics of air-breathing MFCs by removing the need to replace or regenerate the cathode during longterm operation.These results indicate that the installation of a microbial separator is an effective means of stabilizing power generation and ensuring the cost-effective performance of air-breathing MFCs intended for future industrial applications. | Chao Li Kexin Yi Shaogang Hu Wulin Yang | 2023 | Environmental Science and Ecotechnology2023，，3： | 0 |
| 8 | Asymmetric synthesis of pyrrolo[1,2-a]indoles via organocatalytic[3+2]annulation of substituted 2-vinylindoles with azlactones显示文摘The chiral phosphoric acid catalyzed asymmetric[3+2]annulation of substituted 2-vinylindoles with azlactones has been established.This reaction represented a practical approach for the synthesis of structurally diverse pyrrolo[1,2-a]indoles with two vicinal stereocenters including one tetrasubstituted stereocenter in good yields and good stereoselectivities under mild conditions. | Wulin Yang Hao Wang Zirong Pan Zhong Li Weiping Deng | 2020 | Chinese Chemical Letters2020，31，3： | 0 |
| 9 | Organocatalytic asymmetric [3+3] annulation of isatin N,N’-cyclic azomethine imines with enals:Efficient approach to functionalized spiro N-heterocyclic oxindoles显示文摘An unprecedented chiral secondary amine-catalyzed [3+3] annulation of isatin N,N’-cyclic azomethine imines with α,β-unsaturated aldehydes was developed.This strategy allowed the construction of structurally novel spiro N-heterocyclic oxindole derivatives in good yields(up to 91%) and good to excellent enantioselectivities(up to>99% ee),albeit with modest diastereoselectivities(up to 3.1:1 dr). | Boqi Gu Shuxiao Wu Hui Xu Wulin Yang Zhixiang Liu Weiping Deng | 2021 | Chinese Chemical Letters2021，32，2： | 0 |
| 10 | 低轨大规模星座对空间碎片环境的影响及其应对措施显示文摘Large constellations have developed rapidly in recent years because of their unique advantages, but they will inevitably have a major negative impact on the space debris environment, leading to its deterioration. The key to mitigate the impact is the success rate and duration of the post-mission disposal(PMD) process. Aiming at solving this problem, this paper further studies the impact of large constellations on other space assets under different PMD strategies through simulation, and proposes corresponding strategies and suggestions for mitigation.According to One Web’s large constellation launch plan, the dangerous intersection of the large constellation with existing space assets at different stages of the constellations life cycle is calculated by simulation. Based on this, the influence of the large constellation operation on existing space assets at different times and strategies of PMD is analyzed. The conclusion shows that in the PMD stage, large constellations have the greatest impact on existing space assets;the PMD duration and number of satellites performing PMD at the same time are key factors to the degree of negative impact. The faster the PMD is, the less threat it poses to other spacecraft. More results and conclusions are still being analyzed. | CHEN Chuan YANG Wulin GONG Zizheng ZHANG Pinliang LI Ming | 2020 | Aerospace China2020，21，2： | 0 |
| 11 | Diastereoselective synthesis of functionalized tetrahydro-γ-carbolines via a[3+3] cycloaddition of 2,2’-diester aziridines with β-(indol-2-yl)-α,β-unsaturated ketones显示文摘A Sc(OTf)3-catalyzed[3+3]cycloaddition of 2,2’-diester aziridines withβ-(indol-2-yl)-α,β-unsaturated ketones was developed,affording polysubstituted tetrahydro-y-carbolines in single diastereoisomers in good to excellent yields. | Xuejie Zou Yangzi Liu Shaojing Shang Wulin Yang Weiping Deng | 2020 | Chinese Chemical Letters2020，31，5： | 0 |
| 12 | Characterization of amyloid-β precursor protein intracellular domain-associated transcriptional complexes in SH-SY5Y neurocytes显示文摘Objective Alzheimer's disease (AD) is one of the major disorders worldwide. Recent research suggests that the amyloid-β precursor protein intracellular domain (AICD) is a potential contributor to AD development and progression. The small AICD is rapidly degraded after processing from the full-length protein. The present study aimed to apply a highly efficient biotinylation approach in vitro to study AICD-associated complexes in neurocytes. Methods By coexpressing Escherichia coli biotin ligase with biotinyl-tagged AICD in the SH-SY5Y neuronal cell line, the effects of AICD overexpression on cell proliferation and apoptosis were analyzed. Besides, AICD-associated nuclear transcriptional complexes were purified and then examined by mass spectrometry. Results Our data showed that AICD overexpression not only affected cell proliferation but also led to apoptosis in differentiated SH-SY5Y cells. Moreover, biotinylation allowed single-step purification of biotinylated AICD-associated complexes from total nuclear extract via high-affinity biotin-streptavidin binding. Following this by mass spectrometry, we identified physically associated proteins, some reported previously and other novel binding partners, CUX1 and SPT5. Conclusion Based on these results, a map of the AICD-associated nuclear interactome was depicted. Specifically, AICD can activate CUX1 transcriptional activity, which may be associated with AICD-dependent neuronal cell death. This work helps to understand the AICD-associated biological events in AD progression and provides novel insights into the development of AD. | Wulin Yang Amy Yong Chen Lau Shuizhong Luo Qian Zhu Li Lu | 2012 | Neuroscience Bulletin2012，28，3： | 0 |
| 13 | HMGB3 is a potential diagnostic marker for early cervical lesion screening显示文摘Despite the spread of effective vaccination strategies,cervical cancer remains the second leading cause of cancer death among women aged 20 to 39.1 clinical diagnosis of cervical lesions relies on the P16INK4a(P16)marker,but its sensitivity to low-grade cervical intraepithelial neoplasia(CIN)is limited.Exploring more sensitive and specific molecular markers is still a challenge in cervical lesion screening.In this study,we found that HMGB3 could effectively label pathological cells in different cervical lesions,especially for early CIN.Therefore,HMGB3 has the potential to be used as a novel marker for the early screening of cervical lesions. | Qianwen Cui Jiarong Zhao Qingmei Deng Yu Liu Changfang Fu Qiang Wu Qiuyan Sun Haiyan Weng Haiming Dai Wulin Yang | 2023 | Genes & Diseases2023，10，6： | 0 |
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