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| 1 | Potential and Suitability Evaluation of CO_2 Geological Storage in Major Sedimentary Basins of China,and the Demonstration Project in Ordos Basin显示文摘From 2010 to 2012, the China Geological Survey Center for Hydrogeology and Environmental Geology Survey(CHEGS) carried out the project 'Potential evaluation and demonstration project of CO2 Geological Storage in China'. During this project, we developed an evaluation index system and technical methods for the potential and suitability of CO2 geological storage based on China's geological conditions, and evaluated the potential and suitability of the primary basins for CO2 geological storage, in order to draw a series of regional scale maps(at a scale of 1:5000000) and develop an atlas of the main sedimentary basins in China. By using these tools, we delineated many potential targets for CO2 storage. We also built techniques and methods for site selection and the exploration and assessment of CO2 geological storage in deep saline aquifers. Furthermore, through cooperation with the China Shenhua Coal to Liquid and Chemical Co., Ltd., we successfully constructed the first coal-based demonstration project for CO2 geological storage in deep saline aquifers in the Yijinhuoluo Banner of Ordos in the Inner Mongolia Autonomous Region, which brought about the basic preliminary theories, techniques, and methods of geological CO2 storage in deep saline aquifers under China's geological conditions. | GUO Jianqiang WEN Dongguang ZHANG Senqi XU Tianfu LI Xufeng DIAO Yujie JIA Xiaofeng | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 8 |
| 2 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 3 | Tenofovir vs.entecavir on recurrence of hepatitis B virus-related hepatocellular carcinoma beyond Milan criteria after hepatectomy显示文摘Background:Hepatectomy for hepatocellular carcinoma(HCC)beyond the Milan criteria is shown to be beneficial.However,a high rate of post-operative HCC recurrence hinders the long-term survival of the patients.This study aimed to investigate and compare the impacts of tenofovir(TDF)and entecavir(ETV)on the recurrence of hepatitis B viral(HBV)-related HCC beyond the Milan criteria.Methods:Data pertaining to 1532 patients who underwent hepatectomy and received antiviral therapy between January 2014 and January 2019 were collected from five centers.Recurrence-free survival(RFS)analysis was performed using the Kaplan-Meier method.Cox proportional hazards regression analysis was performed to determine prognostic factors for HCC recurrence.Results:The analysis incorporates 595 HBV-related HCC patients.The overall 5-year RFS was 21.3%.Among them,533 and 62 patients received ETV and TDF treatment,respectively.The 1-,3-,and 5-year RFS rates were 46.3%,27.4%,and 19.6%,respectively,in the ETV group compared with 65.1%,41.8%,and 37.2%,respectively,in the TDF group(P<0.001).Multivariate analysis showed that TDF treatment(hazard ratio[HR]:0.604,P=0.005),cirrhosis(HR:1.557,P=0.004),tumor size(HR:1.037,P=0.008),microvascular invasion(MVI)(HR:1.403,P=0.002),portal vein tumor thrombus(PVTT)(HR:1.358,P=0.012),capsular invasion(HR:1.228,P=0.040),and creatinine levels(CREA)(HR:0.993,P=0.031)were statistically significant prognostic factors associated with RFS.Conclusions:Patients with HCC beyond the Milan criteria exhibited a high rate of HCC recurrence after hepatectomy.Compared to the ETV therapy,TDF administration significantly lowered the risk of HCC recurrence. | Junyi Shen Weili Qi Junlong Dai Shusheng Leng Kangyi Jiang Yu Zhang Shun Ran Chuan Li Tianfu Wen | 2022 | Chinese Medical Journal2022，，3： | 3 |
| 4 | Large electrocaloric effect in BaTiO_3 based multilayer ceramic capacitors显示文摘The electrocaloric effect(ECE) of multilayer ceramic capacitor(MLCC) of Y5 V type was directly measured via a differential scanning calorimetry(DSC) method and a reference resistor was used to calibrate the heat flow due to the heat dissipation. The results are compared with those calculated from Maxwell relations by using the polarization data obtained from the polarization–electric field hysteresis loops. The direct method shows a larger ECE temperature change, which is accounted for the situation approaches an ideal condition. For the indirect method using Maxwell relations, only the polarization projection along the electric field was taken into account, which will be less than the randomly distributed real polarizations that contribute to the ECE. The MLCCs exhibit a broad peak of ECE around 80 C, which will be favorite for the practical ECE cooling devices. | LU Biao WEN XinHua TANG ZhenHua LIANG Bo TAO Tao XIE ZhiWei ZHANG TianFu TANG XinGui XIANG Yong LIAO Jie LU ShengGuo | 2016 | Science China(Technological Sciences)2016，59，7： | 3 |
| 5 | Use of donor-specific red blood cell transfusions for patients undergoing liver transplantation during the COVID-19 pandemic显示文摘Background:Increased risks have been found for patients undergoing liver transplantation due to the blood supply shortage following the ongoing coronavirus disease 2019(COVID-19)pandemic.Hence,exploring a method to alleviate this dilemma is urgent.This phase I,nonrandomized,prospective trial aimed to evaluate the safety and feasibility of using donor-specific red blood cell transfusion(DRBCT)as an urgent measurement to alleviate the blood supply shortage in deceased donor liver transplantation(DDLT).Methods:The outcomes of 26 patients who received DRBCT and 37 patients in the control group who only received 3rd party packed red blood cells(pRBCs)transfusion between May 2020 and January 2021 were compared.Results:Patients receiving DRBCT did not develop transfusion-related complications,and the incidence of postoperative infection was similar to that in the control group(23.1%vs.18.9%,P=0.688).Because the patients received the red blood cells from organ donors,the median volume of intraoperative allogeneic red blood cell transfusion from blood bank was 4.0 U(IQR 1.1-8.0 U)in the DRBCT group,which is significantly lower than that(7.5 U,IQR 4.0-10.0 U)in the control group(P=0.018).The peak aspartate aminotransferase(AST)level was significantly lower in the DRBCT group than in the control group(P=0.008)and so were the AST levels in the first two days after the operation(P=0.006 and P=0.033).Conclusions:DRBCT is a safe and effective procedure to lower the need for blood supply and is associated with a reduction in AST levels after transplantation.DRBCT is beneficial to patients receiving life-saving transplantation without sufficient blood supply during the COVID-19 pandemic. | Tao Lv Xi Xu Jiulin Song Yifei Tan Li Jiang Jian Yang Diao He Lingxiang Kong Weiyi Zhang Panyu Chen Qiwen Xiang Tao Zhu Hong Wu Tianfu Wen Jiayin Yang | 2021 | Hepatobiliary Surgery and Nutrition2021，10，4： | 2 |
| 6 | Prevent Small-For-Size Syndrome Using Dual Grafts in Living Donor Liver Transplantation显示文摘 | Zheyu Chen LuNan Yan Bo Li Yong Zeng TianFu Wen JiChun Zhao WenTao Wang MingQing Xu Jiayin Yang | 2009 | Journal of Surgical Research2009，，2： | 1 |
| 7 | Bleeding treatment options for primary liver cancer 显示文摘 | Rayong Hang Li Chuan Wen Tianfu | 2011 | Huaxi Medi2011，5，1： | 1 |
| 8 | Conversion resection for patients with hepatocellular carcinoma and inferior vena cava tumor thrombus: a consecutive case series显示文摘To the Editor:The incidence of hepatocellular carcinoma(HCC)with inferior vena cava tumor thrombus(IVCTT)is.approximately 1.4%.Owing to direct cancercll dissemination into the systemic circulation,HCC-IVCTT is frequently associated with synchronous and metachronous extrahepatic metastasis.Without treatment,the median survival time is only 3 months for patients with HCC-IVCTT. | Xiaoyun Zhang Wei Peng Chuan Li Wusheng Lu Zhiping Li Jiayin Yang Tianfu Wen | 2022 | Chinese Medical Journal2022，，12： | 1 |
| 9 | Safety of elective hepatectomy performed on weekend for patients with hepatocellular carcinoma显示文摘The incidence of hepatocellular carcinoma(HCC)is increasing year by year.The International Agency for Research on Cancer(IARC)reported that more than 630,000 people were diagnosed with HCC in 2020 and more than half of new cases of HCC were in China.The increasing number of patients overburdens the medical system and the waiting time before the surgery becomes longer and longer.This poses a new challenge to the applicability of traditional surgical management model.The elective surgery performed on weekend could provide an efficient solution to the problem.However,the safety of weekend surgery is controversial because surgical patients have a higher severe complication incidence and postoperative mortality on the weekend compared to the weekday(ie,weekend effect). | Junlong Dai Junyi Shen Xiaoyun Zhang Wei Peng Tianfu Wen Chuan Li | 2022 | Chinese Medical Journal2022，135，21： | 0 |
| 10 | Effect of Additive on the Microstructure of Electro-deposited Nanocrystalline Ni-Fe Alloy显示文摘 | YU Jinku JING Tianfu LI Qun YANG Jun ZHANG Falun SONG Hao WEN Ruisheng | 2008 | 金属材料研究2008，34，2： | 0 |
| 11 | Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China显示文摘The aim of this paper is to report the authors’experience in performing adult-to-adult living donor liver transplantation(LDLT)by using a modified technique in using grafts of the right lobe of the liver.From January 2002 to September 2006,56 adult patients underwent LDLT using right lobe grafts at the West China Hospital,Sichuan University Medical School,China.All patients underwent a modified operation designed to improve the reconstruction of the right hepatic vein(RHV)and the tributariers of the middle hepatic vein(MHV)by interposing a vessel graft,and by anastomosing the hepatic arteries and bile ducts.There were no severe complications or deaths in all donors.Fifty-two(92.8%)recipients survived the operations.Among the 56 recipients,complications were seen in 15 recipients(26.8%),including hepatic vein stricture(one case),small-for-size syndrome(one case),hepatic artery thrombosis(two cases),intestinal bleeding(one case),bile leakage(two cases),left subphrenic abscess(one case),renal failure(two cases)and pulmonary infection(five cases).Within three months after transplantation,four recipients(7.14%)died due to smallfor-size syndrome(one case),renal failure(one case)and multiple organ failure(two cases).All patients underwent direct anastomoses of the RHV and the inferior vena cava(IVC),and in 23 cases,reconstruction of the right inferior hepatic vein was also done.In 24 patients,the reconstruction of the tributaries of the MHV was also done by interposing a vessel graft to provide sufficient venous outflow.Trifurcation of the portal vein was seen in nine cases.Thus,veno-plasty or separate anastomoses were performed.The graft and recipient body weight ratios(GRWR)were between 0.72%and 1.43%,and in three cases it was<0.8%.The graft weight to recipient standard liver volume ratios(GV/SLV)were between 31.86%and 71.68%,among which four cases had<40%.No“small-for-size syndrome”occurred.With modification of the surgical technique,especially in the reconstruction of the hepatic vein to provide sufficient venous outflow,living donor liver grafts in adults using the right lobe of the liver can become a relatively safe procedure and prevent the“small-for-size syndrome”. | YAN Lunan LI Bo ZENG Yong WEN Tianfu ZHAO Jichun WANG Wentao YANG Jiayin XU Mingqing MA Yukui CHEN Zheyu LIU Jiangwen WU Hong | 2007 | Frontiers of Medicine2007，1，2： | 0 |
| 12 | Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe graft:experience of 124 cases显示文摘The aim of this paper is to summarize our experience of using right lobe liver grafts to reduce biliary complications in adult-to-adult(A-A)living donor liver transplantation(LDLT).From January 2002 to October 2007,124 adult patients underwent living donor liver transplantation using right lobe grafts at the West China Hospital,Sichuan University Medical School,China.There was no death in all donors.Biliary reconstruction for 178 hepatic duct orifices from 124 donor grafts was performed which included 106 reconstructions of duct-to-duct anastomoses and 72 cholangiojejunostomy.Nine recipients had biliary complications including six bile lea-kages(four from the anastomotic site and two from the cut surface of the liver graft)and three biliary strictures.With the improved techniques for biliary reconstruction,we have achieved good results in 124 recipients of A-A LDLT.We ascribe our success to the introduction of microsurgical techniques and the use of fixed operators which help in decreasing the biliary complications of LDLT. | Lunan YAN Tianfu WEN Wentao WANG Jiayin YANG Mingqing XU Zheyu CHEN Hong WU | 2008 | Frontiers of Medicine2008，2，2： | 0 |
| 13 | Can a laparoscopic surgery be an alternative to transjugular intrahepatic portosystemic shunts (TIPS) for the treatment of portal hypertensive bleeding?显示文摘We read with great confusion the guidance written by Garcia-Tsao et al.(1).In the practice guidance developed by the American Association for the Study of Liver Diseases(AASLD),there is no trail of surgical operation for the treatment of portal hypertensive bleeding in cirrhosis at all.However,it is well known that surgical shunts played an important role in this setting before the emergence of transjugular intrahepatic portosystemic shunts(TIPS),existing studies have shown that surgical shunt still has better long-term patency and survival than TIPS(2),and surgical portoazygous devascularization is still considered as the most direct and effective way of hemostasis in some countries(3). | Bin Huang Tianfu Wen | 2023 | Hepatobiliary Surgery and Nutrition2023，12，1： | 0 |
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