|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma显示文摘 | Kai Feng Jun Yan Xiaowu Li Feng Xia Kuansheng Ma Shuguang Wang Ping Bie Jiahong Dong | 2012 | Journal of Hepatology2012，，4： | 5 |
| 2 | Comparison of nonhuman primates identified the suitable model for COVID-19显示文摘Identification of a suitable nonhuman primate(NHP)model of COVID-19 remains challenging.Here,we characterized severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in three NHP species:Old World monkeys Macaca mulatta(M.mulatta)and Macaca fascicularis(M.fascicularis)and New World monkey Callithrix jacchus(C.jacchus).Infected M.mulatta and M.fascicularis showed abnormal chest radiographs,an increased body temperature and a decreased body weight.Viral genomes were detected in swab and blood samples from all animals.Viral load was detected in the pulmonary tissues of M.mulatta and M.fascicularis but not C.jacchus.Furthermore,among the three animal species,M.mulatta showed the strongest response to SARS-CoV-2,including increased inflammatory cytokine expression and pathological changes in the pulmonary tissues.Collectively,these data revealed the different susceptibilities of Old World and New World monkeys to SARS-CoV-2 and identified M.mulatta as the most suitable for modeling COVID-19. | Shuaiyao Lu Yuan Zhao Wenhai Yu Yun Yang Jiahong Gao Junbin Wang Dexuan Kuang Mengli Yang Jing Yang Chunxia Ma Jingwen Xu Xingli Qian Haiyan Li Siwen Zhao Jingmei Li Haixuan Wang Haiting Long Jingxian Zhou Fangyu Luo Kaiyun Ding Daoju Wu Yong Zhang Yinliang Dong Yuqin Liu Yinqiu Zheng Xiaochen Lin Li Jiao Huanying Zheng Qing Dai Qiangming Sun Yunzhang Hu Changwen Ke Hongqi Liu Xiaozhong Peng | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 3 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 4 | Effects of substance P on growth of fibroblast-like cells derived from bile duct: an in vitro cell culture study显示文摘 | Tian Yuanhu Yang Guangyun Zhang Xiaoqing Shen Wei Dong Jiahong Xu Zhi | 2014 | Chinese Medical Journal2014，，17： | 3 |
| 5 | Endoscopic or laparoscopic approach for hepatolithiasis in the era of endoscopy in China显示文摘 | JingWang Tan YunChang Tan Fei Chen YuL. Zhu JianJun Leng JiaHong Dong | 2015 | Surgical Endoscopy2015，，1： | 2 |
| 6 | Utilization threshold of surface water and groundwater based on the system optimization of crop planting structure显示文摘Based on the diversity of the agricultural system, this research calculates the planting structures of rice, maize and soybean considering the optimal economic-social-ecological aspects. Then, based on the uncertainty and randomness of the water resources system,the interval two-stage stochastic programming method,which introduces the uncertainty of the interval number, is used to calculate the groundwater exploitation and the use efficiency of surface water. The method considers the minimum cost of water as the objective of the uncertainty model for surface water and groundwater joint scheduling optimization for different planting structures. Finally, by calculating harmonious entropy, the optimal exploitation utilization interval of surface water and groundwater is determined for optimal cultivation in the Sanjiang Plain.The optimal matching of the planting structure under the economic system is suitable when the mining ratio of the surface is in 44.13%–45.45% and the exploitation utilization of groundwater is in 54.82%–66.86%, the optimal planting structure under the social system is suitable when surface water mining ratio is in 47.84%–48.04% and the groundwater exploitation threshold is in 67.07%–72.00%. This article optimizes the economicsocial-ecological-water system, which is important for the development of a water- and food-conserving society and providing a more accurate management environment. | Qiang FU Jiahong LI Tianxiao LI Dong LIU Song CUI | 2016 | Frontiers of Agricultural Science and Engineering2016，3，3： | 2 |
| 7 | Precision in Liver Surgery显示文摘 | Jiahong Dong ShiZhong Yang Jianping Zeng Shouwang Cai Wenbin Ji Weidong Duan Aiqun Zhang Weizheng Ren Yinzhe Xu Jingwang Tan Xiangyang Bu Ning Zhang Xuedong Wang Xianqiang Wang Xiangfei Meng Kai Jiang Wanqing Gu Zhiqiang Huang | 2013 | Semin Liver Dis2013，，03： | 2 |
| 8 | Grain refinement of Mg-3Y alloy using Mg-10Al_(2)Y master alloy显示文摘The as-extruded Mg-10Al_(2)Y master alloy was chosen as a novel grain refiner for as-cast Mg-3Y alloy.Contrast samples of cast Mg-3Y alloy added with pure Al and Mg-Zr master alloy grain refiners were prepared under the same conditions.In this study,the influence of addition amounts of Al_(2)Y and holding time on grain refinement efficiency as well as tensile properties was investigated.And the grain refining ability of the Al_(2)Y particles was systematically evaluated in terms of the addition amounts,number density of the Al_(2)Y particles and holding time.The finest grains are achieved at 2 wt% Al_(2)Y addition amount,which corresponds to number density of the polygonal Al_(2)Y particles of 420-460 mm^(-2).The Mg-10Al_(2)Y master alloy has significant refinement performance and no refining recession occurs at the holding time within 60 min,or the settling time up to 180 min.Grain refinement and the second phase strengthening of uniformly distributed Al_(2)Y particles contribute to the simultaneous enhancement on both strength and elongation of Mg-3Y alloy. | Zhongtao Jiang Xiang Meng Bin Jiang Shan Jiang Jiahong Dai Jingren Dong Yongfeng Ding | 2021 | Journal of Rare Earths2021，39，7： | 2 |
| 9 | A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma显示文摘 | Kai Feng Jun Yan Xiaowu Li Feng Xia Kuansheng Ma Shuguang Wang Ping Bie Jiahong Dong | 2012 | Journal of Hepatology2012，，4： | 2 |
| 10 | Recent progress in perovskite solar cells:from device to commercialization显示文摘Perovskite solar cells(PSCs) are undergoing rapid development and the power conversion efficiency reaches 25.7% which attracts increasing attention on their commercialization recently.In this review,we summarized the recent progress of PSCs based on device structures,perovskite-based tandem cells,large-area modules,stability,applications and industrialization.Last,the challenges and perspectives are discussed,aiming at providing a thrust for the commercialization of PSCs in the near future. | Xinhui Luo Xuesong Lin Feng Gao Yang Zhao Xiaodong Li Liqing Zhan Zexiong Qiu Jin Wang Cong Chen Lei Meng Xiaofeng Gao Yu Zhang Zijian Huang Rundong Fan Huifen Liu Yanrun Chen Xiaoxue Ren Jiahong Tang Chun-Hao Chen Dong Yang Yongguang Tu Xiao Liu Dongxue Liu Qing Zhao Jingbi You Junfeng Fang Yongzhen Wu Hongwei Han Xiaodan Zhang Dewei Zhao Fuzhi Huang Huanping Zhou Yongbo Yuan Qi Chen Zhaokui Wang Shengzhong(Frank)Liu Rui Zhu Jotaro Nakazaki Yongfang Li Liyuan Han | 2022 | Science China Chemistry2022，65，12： | 1 |
| 11 | The Practical Value of Applying Chemical Biliary Duct Embolization to Chemical Hepatectomy for Treatment of Hepatolithiasis显示文摘 | Fuyu Li Jingqiu Cheng Sheng He Ning Li Mingming Zhang Jiahong Dong Lisheng Jiang Nansheng Cheng Xianzhe Xiong | 2005 | Journal of Surgical Research2005，，2： | 1 |
| 12 | Precise anatomical resection of the ventral part of Segment VIII显示文摘 | Canhong Xiang Zhe Liu Jiahong Dong Keiji Sano Masatoshi Makuuchi | 2014 | International Journal of Surgery Case Reports2014，，： | 1 |
| 13 | The Pringle manoeuvre should be avoided in hepatectomy for cancer patients due to its side effects on tumor recurrence and worse prognosis显示文摘 | Feng Xiaobin Liu Zipei Zheng Shuguo Dong Jiahong Li Xiaowu | 2009 | Medical Hypotheses2009，，4： | 1 |
| 14 | Feasibility of Reduced-size Orthotopic Liver Transplantation with Fatty Grafts and its Potential Regeneration in Rats显示文摘 | Ye Sheng Dong Jiahong Han Benli | 2009 | Archives of Medical Research2009，，3： | 1 |
| 15 | Endogenous Bile Salts Are Associated With Bile Duct Injury in the Rat Liver Transplantation Model显示文摘 | Geng Chen Shuguang Wang Ping Bie Xiaowu Li Jiahong Dong | 2009 | Transplantation2009，，3： | 1 |
| 16 | Radiofrequency ablation for hypersplenism in patients with liver cirrhosis: A pilot study显示文摘 | Quanda Liu M.D. Kuansheng Ma M.D. Zhenping He M.D. Jiahong Dong M.D. Xin Hua M.D. Xuequan Huang M.D. Liang Qiao M.D. Ph.D | 2005 | Journal of Gastrointestinal Surgery2005，，5： | 1 |
| 17 | Exploring impact of street layout on urban flood risk of people and vehicles under extreme rainfall based on numerical experiments显示文摘Urban street layout is an important factor in the formation process, characteristics, and risk level of urban flooding;therefore, this study numerically investigates the impact of street layout on urban flood risk to people and vehicles. Four typical street-layout scenarios with areas of 3 km × 3 km are established based on a block-scale investigation. The layout types are regular grid,irregular grid, radial, and annular. Urban inundation models are then constructed for these typical street layouts based on the twodimensional(2D) hydrodynamic method. Two historic, extreme rainfall events, which occurred in Beijing on July 21, 2012 and in Zhengzhou on July 20, 2021, are used as rainstorm scenarios for urban inundation modelling. The flood risks to people and vehicles are then calculated. Results show that, for an extreme rainstorm on the block scale, the street layout impacts the spatial and temporal distributions of the inundation variables, which include the water depth, flow velocity, flood volume, and inundated area. Moreover, for the same extreme-rainfall scenario, the greatest differences in the total flood volume, maximum street-water depth, and maximum street-flow velocity caused by street-layout differences are 17.22%, 60.25%, and 61.50%, respectively.Among the four street layouts considered in this study, the annular street layout exhibits the lowest degrees of inundation and flood risk. For the same extreme-rainfall scenario, the proportions of high-risk road sections for adults and children in this layout are 58.89% and 62.28% smaller than those for the layout with the largest proportion of high-risk road sections, respectively;the proportions of high-risk road sections for the Honda Accord and Audi Q7 were 55.31% and 53.04% smaller, respectively. The findings of this study may aid scientific understanding and development of “flood-sensitive” block-scale street layouts and urban planning in the context of the changing environment. | MEI Chao LIU JiaHong SHI HongYuan WANG Hao WANG Jia DONG LiRong SONG TianXu ZHANG HaiJia | 2023 | Science China(Technological Sciences)2023，66，9： | 1 |
| 18 | Radiofrequency ablation for hypersplenism in patients with liver cirrhosis: A pilot study显示文摘 | Quanda Liu Kuansheng Ma Zhenping He Jiahong Dong Xin Hua Xuequan Huang Liang Qiao | 2005 | Journal of Gastrointestinal Surgery2005，，5： | 1 |
| 19 | The Regulating Effect of CCK and Gastrin on Apoptosis of Bile Duct Carcinoma Cells显示文摘Objective:Probe into the influence and the mechanisms of CCK and gastrin on the apoptosis of bile duct carcinoma cells. Methods:By taking beauvericin as the revulsant to the apoptosis of bile duct carcinoma cells, the influence of CCK and gastrin on the apoptosis of bile duct carcinoma cells was investigated by using the teehniques such as TUNEL fluorescent staining, stream mode cell detecting instrument and reverse bcl-2 oligonucleotide. Techifiques of immunohistochemistry, in situ hybridization,flow cytometry(FCM),RT-PCR were used to study the roles of apoptosis-related genes bcl-2 and bax Results:After beauvericin 40 μM worked for 12 h, the survival rate of QBC939 bile duct carcinoma cells was decreased by 35%-40%.About 80% of the bile duct carcinoma cells showed various degrees of apoptosis.CCK and gastrin could upregulate the threshold value of the apoptosis of bile duct carcinoma cells, which could be inhibited by L60,L18 and reverse bcl-2 oligonucleotide. In terms of both transcription and translating levels,CCK and gastrin could obviously promote the genetic expression of bel-2,but had no influence on the genetic expression of bax. Addition of CCK-A receptor or CCK-B/gastr in receptor antagonist could remarkably inhibit the expression of bel-2 boosted by gastrin-17 and CCK-8S. Conclusion:CCK and gastrin inhibited the apoptosis of bile duct carcinoma cells through upregulating the genetic expression of bcl-2.Theoretically, this research has expanded our understanding to the mechanism of CCK and gastrin in controlling the growth of tumors, enriched our view to the mechanism of apoptosis of alimentary tract tumors, and has provided a new thinking for the assistant treatment to bile duct carcinoma cells as well. | MA Kuansheng, ZHANG Fengshen, HE Zhenping, DONG Jiahong The Institute of Hepatobiliary Surgery of PLA, Southwest Hospital, Third Military Medical University, Chongqing 400038, China | 2002 | The Chinese-German Journal of Clinical Oncology2002，1，1： | 0 |
| 20 | Pathogenesis of Biliary Filling Defect-Related Complications Following Orthotopic Liver Transplantation显示文摘 | Yu He Leida Zhang Qian Lu Jun Din Zhanyu Yang Zhihua Li Ping Bie Shuguang Wang Jiahong Dong | 2007 | 器官移植内科学杂志2007，2，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员