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| 1 | Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial显示文摘 | Ann-Lii Cheng Yoon-Koo Kang Zhendong Chen Chao-Jung Tsao Shukui Qin Jun Suk Kim Rongcheng Luo Jifeng Feng Shenglong Ye Tsai-Sheng Yang Jianming Xu Yan Sun Houjie Liang Jiwei Liu Jiejun Wang Won Young Tak Hongming Pan Karin Burock Jessie Zou Dimitris Volio | 2009 | Lancet Oncology2009，，1： | 23 |
| 2 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 3 | Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens显示文摘Naturally,resistant crop germplasms are important resources for managing the issues of agricultural product safety and environment deterioration.We found a spontaneous mutant of‘Newhall’navel orange(Citrus sinensis Osbeck)(MT)with broad-spectrum protections against fungal pathogens in the orchard,postharvest-storage,and artificial inoculation conditions.To understand the defense mechanism of MT fruit,we constructed a genome-scale metabolic network that integrated metabolome and transcriptome datasets.The coordinated transcriptomic and metabolic data were enriched in two sub-networks,showing the decrease in very long chain fatty acid(by 41.53%)and cuticular wax synthesis(by 81.34%),and increase in the synthesis of jasmonic acid(JA)(by 95.23%)and JA-induced metabolites such as 5-dimethylnobietin(by 28.37%)in MT.Furthermore,cytological and biochemical analyses confirmed that the response to fungal infection in MT was independent of wax deficiency and was correlated with the levels of jasmonates,and the expression of plant defensin gene PDF1.2.Results of exogenous application of MeJA and JA inhibitors such as propyl gallate proved that JA-mediated defense contributes to the strong tolerance against pathogens in MT.Our results indicated that jasmonate biosynthesis and signaling are stimulated by the fatty acid redirection of MT,and participate in the tolerance of pathogenic fungi. | Yizhong He Jingwen Han Runsheng Liu Yuduan Ding Jinqiu Wang Li Sun Xiaoming Yang Yunliu Zeng Weiwei Wen Juan Xu Hongming Zhang Xiang Yan Zhaoxing Chen Zuliang Gu Hong Chen Huanqing Tang Xiuxin Deng Yunjiang Cheng | 2018 | Horticulture Research2018，5，1： | 8 |
| 4 | Mass-independent fractionation of even mercury isotopes显示文摘Practically all physical, chemical, and biological processes can induce mass-dependent fractionation of mercury(Hg) isotopes. A few special processes such as photochemical reduction of Hg(II) and photochemical degradation of methylmercury(Me Hg) can produce massindependent fractionation(MIF) of odd Hg isotopes(oddMIF), which had been largely reported in variable natural samples and laboratory experiments, and was thought to be caused by either nuclear volume effect or magnetic isotope effect. Recently, intriguing MIF of even Hg isotopes(evenMIF) had been determined in natural samples mainly related to the atmosphere. Though photo-oxidation in the tropopause(inter-layer between the stratosphere and the troposphere) and neutron capture in space were thought to be the possible processes causing even-MIF, the exact mechanism triggering significant even Hg isotope anomaly is still unclear. Even-MIF could provide useful information about the atmospheric chemistry and related climate changes, and the biogeochemical cycle of Hg. | Hongming Cai Jiubin Chen | 2016 | Science Bulletin2016，61，2： | 7 |
| 5 | Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study)显示文摘 | Lin Shen Jin Li Jianming Xu Hongming Pan Guanghai Dai Shukui Qin Liwei Wang Jinwan Wang Zhenzhou Yang Yongqian Shu Ruihua Xu Lei Chen Yunpeng Liu Shiying Yu Lilian Bu Yongzhe Piao | 2015 | Gastric Cancer2015，，1： | 7 |
| 6 | Size-controlled MoS2 nanodots supported on reduced graphene oxide for hydrogen evolution reaction and sodium-ion batteries显示文摘转变金属 dichalcogenide nanodots (ND ) 收到了可观的兴趣。我们由在 oleylamine 把铝 pentachloride 和 L 半胱氨酸用作先锋为瞬间 2 ND 报导一条灵巧的自底向上的合成线路。有从 2.2 ~ 5.3 nm 的狭窄的尺寸分布的 ND 的合成,被控制反应时间定制。因为它的涂层特征, oleyalmine 导致 ND 的一致性和 monodispersity。而且, ND 综合了有大特定的表面区域提供活跃地点。Graphene 拥有突出的电导率。联合二材料的优点,因为 2D, 0D/2D 材料展出优异电气化学的性能为离子吸附,精力存储,和变换的可渗透的隧道。同样准备的瞬间 2/rGO (~ 2.2 nm ) 显示出 220 mAhroscopy 分析的一个稳定的能力。与另外的报导金属 oxide/CN composites 比较,有 TiO 2 nanoparticles 的 ultrathin CN-NSs 层的强壮的相互作用制止他们的重新叠,哪个导致 234.0 m 2 的一个大特定的表面区域吗? | Weiyi Sun Pan Li Xue Liu Jiajia Shi Hongming Sun Zhanliang Tao Fujun Li Jun Chen | 2017 | Nano Research2017，10，7： | 6 |
| 7 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 8 | Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the phase III Sorafenib Asia–Pacific trial显示文摘 | Ann-Lii Cheng Zhongzhen Guan Zhendong Chen Chao-Jung Tsao Shukui Qin Jun Suk Kim Tsai-Sheng Yang Won Young Tak Hongming Pan Shiying Yu Jianming Xu Fang Fang Jessie Zou Giuseppe Lentini Dimitris Voliotis Yoon-Koo Kang | 2011 | European Journal of Cancer2011，，10： | 4 |
| 9 | Detection of Citrus yellow vein clearing virus by Quantitative Real-time RT-PCR显示文摘To develop a rapid and reliable detection method for Citrus yellow vein clearing virus(CYVCV), a quantitative real-time reverse transcriptionpolymerase chain reaction(q RT-PCR) system based on SYBR Green I was established by using a pair of specific primers designed from its conserved coat protein gene. The sensitivity, specificity, and applicability of the system were evaluated accordingly. The results showed that amplicons were produced from CYVCV isolates, whereas no amplicons from non-CYVCV citrus virus samples, including Citrus tristeza virus(CTV) and Citrus tatter leaf virus(CTLV), were obtained. The sensitivity of the q RT-PCR was 100-fold higher than that of conventional RT-PCR. An excellent linear correlation(R2= 0.999) was obtained from two standard curves of c RNA, and the amplification efficiency was 102%. The data from field citrus samples detection showed that the q RT-PCR system could be used in determining the concentration of CYVCV in different citrus species. | CHEN Hongming ZHOU Yan WANG Xuefeng ZHOU Changyong YANG Xiuyan LI Zhongan | 2016 | Horticultural Plant Journal2016，2，4： | 4 |
| 10 | Can semipermeable membranes coating materials influence in vivo performance for paliperidone tri-layer ascending release osmotic pump tablet:In vitro evaluation and in vivo pharmacokinetics study显示文摘One purpose of this study was to develop a paliperidone(PAL)tri-layer ascending release pushepull osmotic pump(TA-PPOP)tablet which could meet the needs of clinical applications.And another purpose was to investigate whether different coating materials influenced in vivo performance of TA-PPOP.The ascending release mechanism of this trilayer delivery system on theory was elaborated.TA-PPOP was prepared by means of coating with cellulose acetate(CA)or ethyl cellulose(EC).Several important influence factors such as different core tablet compositions and different coating solution ingredients involved in the formulation procedure were investigated.The optimization of formulation and process was conducted by comparing different in vitro release behaviors of PAL.In vitro dissolution studies indicated that both the two formulations of different coating materials were able to deliver PAL at an ascending release rate during the whole 24 h test.The in vivo pharmacokinetics study showed that both self-made PPOP tablets with different coating had a good in vitro-in vivo correlation(IVIVC)and were bioequivalent with the brand product,which demonstrated no significant influence of the coating materials on the in vivo release acceleration of TA-PPOP. | Guangjing Li Yongjun Wang Hongming Chen Donglei Leng Panqin Ma Yanjie Dong Lifang Gao Zhonggui He | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，2： | 4 |
| 11 | Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial显示文摘 | Ann-Lii Cheng Yoon-Koo Kang Zhendong Chen Chao-Jung Tsao Shukui Qin Jun Suk Kim Rongcheng Luo Jifeng Feng Shenglong Ye Tsai-Sheng Yang Jianming Xu Yan Sun Houjie Liang Jiwei Liu Jiejun Wang Won Young Tak Hongming Pan Karin Burock Jessie Zou Dimitris Volio | 2009 | Lancet Oncology2009，，1： | 3 |
| 12 | A new member of the topological semimetals family显示文摘In topological semimetals(TSMs),the quasi-particle excitations of electrons can be described by the Dirac or Weyl equation,mimicking the elusive massless Dirac or Weyl fermions in the low-frequency regime as emergent phenomena.The realization of elementary excitations,with and even | Hongming Weng Chen Fang Zhong Fang Xi Dai | 2017 | National Science Review2017，4，6： | 3 |
| 13 | Peniazaphilones A—I,Produced by Co-culturing of Mangrove Endophytic Fungi,Penicillium sclerotiorum THSH-4 and Penicillium sclerotiorum ZJHJJ-18显示文摘Co-culturing the mangrove endophytic fungus Penicillium sclerotiorum THSH-4 with Penicillium sclerotiorum ZJHJJ-18 in PDB medium resulted in the production of nine new azaphilones derivatives,peniazaphilones A—I(1-9),and six known azaphilones derivatives(10-15).Their structures were elucidated by analysis of detailed spectroscopic data,single-crystal X-ray diffraction,ECD spectra,^(13)C NMR calculation and DP4+analysis.It is noteworthy that compound 1 with an isoquinoline quinone moiety,was isolated from natural source for the first time.Besides,compound 2 is the third reported phenylhydrazone derivative from fungi.In the bioactivity assays,compounds 1,12,14 and 15(IC_(50)=4.71-17.64μmol/L)exhibited potent inhibition of LPS-induced NO release from RAW264.7 without obvious cytotoxicity within 50μmol/L compared to the positive control indomethacin(IC_(50)=35.27μmol/L).Moreover,compounds 1 and 13 displayed moderate to strong cytotoxicity to A549 and MDA-MB-435,with IC_(50) values in the range of 6.84-14.63μmol/L.Together compound 1 showed moderate broad-spectrum antibacterial activity. | Wencong Yang Jie Yuan Qi Tan Yan Chen Yujia Zhu Hongming Jiang Ge Zou Zhenming Zang Bo Wang Zhigang She | 2021 | Chinese Journal of Chemistry2021，39，12： | 3 |
| 14 | Development and validation of a rapid and sensitive UHPLCeMS/MS method for the determination of paliperidone in beagle dog plasma显示文摘In order to evaluate the pharmacokinetic profile of paliperidone extended-release tablets in vivo,a simple and rapid ultra-high performance liquid chromatographyetandem mass spectrometry(UHPLCeMS/MS)method was developed and validated for the determination of paliperidone in beagle dog plasma.Paliperidone and diazepam(internal standard)were extracted from plasma samples with diethyl ether,and then separated on a C_(18) column(2.1×50 mm,2.6 mm)under gradient elution with methanol-0.1%formic acid at a flow rate of 0.3 ml/min.The compounds were detected using a triple-quadrupole mass spectrometer equipped with an electrospray ionization(ESI)source.The validated method was linear over the concentration range of 1.00-1000.00 ng/ml and the lower limit of quantitation was 1.00 ng/ml.The intra-day and inter-day precision values were not more than 15%(relative standard deviation<20%at low levels),while the accuracy was within±10%of nominal values.The validated UHPLC-MS/MS method was successfully applied to an oral pharmacokinetic study of paliperidone extended-release tablets in a beagle dog. | Hongming Chen Longshan Zhao Guangjing Li Donglei Leng Panqin Ma Lijin Tong Tianhong Zhang | 2014 | Asian Journal of Pharmaceutical Sciences2014，9，5： | 3 |
| 15 | Degradation of 2,4-dichlorophenol catalyzed by the immobilized laccase with the carrier of Fe_3O_4@MSS–NH_2显示文摘With the Fe3O4@MSS(magnetic mesoporous silica spheres)–NH2as the carrier and the glutaraldehyde as crosslinking agent,the immobilized laccase has been prepared and characterized by XRD,IR,SEM and BET etc.Under the optimal conditions,the removal efficiency of2,4-DCP reached 88%and the removal efficiency still remained 61.5%after five cycles of operations.In virtue of GC–MS analysis,2,5-dimethoxyl-1,4-quinone,2-chlorine-1,4-dimethoxyl benzene,3,30-dichlorine-4,40-dimethoxyl biphenyl,maleic acid phenol ester,and three kinds of maleic acid,alcohol ester,and para-hydroxyl phenol ester compounds have been identified as intermediate and final degradation products of 2,4-DCP,respectively.Besides,the degradation products of 2,4-DCP have been confirmed by performing the1H-NMR and13C-NMR experiments,further demonstrating the degradation mechanism of 2,4-DCP by the immobilized laccase. | Yan Huang Yanjie Xi Yuxiang Yang Cheng Chen Hongming Yuan Xiangnong Liu | 2014 | Chinese Science Bulletin2014，59，5： | 3 |
| 16 | Rapid low-temperature synthesis of perovskite/carbon nanocomposites as superior electrocatalysts for oxygen reduction in Zn-air batteries显示文摘 | Zhenhua Yan Hongming Sun Xiang Chen Xiaorui Fu Chengcheng Chen Fangyi Cheng Jun Chen | 2018 | Nano Research2018，11，6： | 2 |
| 17 | Spray,atomization and combustion characteristics of oxygenated fuels in a constant volume bomb:A review显示文摘Biofuels have extensive available resources and have an immense potential as promising alternative fuels for automobile.The application advantages of biofuels are mainly reflected as particulate matter(PM)reduction,carbon neutral,greenhouse gases reduction,waste utilization,energy and economic security,and fuel pluralism.Based on the understanding of molecular structure effects of biofuels on soot formation and particles morphology,the effects of alcohols,ethers,esters and biodiesel on spray and combustion process in constant volume bomb in recent years are retrospectively analyzed in this paper.For the mixture,macromolecular ester fuels and polyoxymethylene dimethyl ether(PODE)are conducive to the improvement of liquid spray,while biodiesel,small molecules,dimethyl ether(DME)and alcohols are reversed.Alcohols are advantageous to the extension of mixing time and the increasing of vapor-phase mixture.Through the influence integrated assessment,alcohols show the best performance on the spray,atomization and combustion,while biodiesels show the worst.But in terms of combustion,PODE is the best choice without considering spray and atomization.For binary alternative-diesel fuel blends,methanol or butanol is the best additive based on synthetically considerations on spray,atomization and combustion.To meet the requirements of the fuel application of diesel engine,ternary fuel or even quaternary fuel have been proposed and explored.This review can help to form a systematic understanding on fuel recombining and obtain the guide of clean and efficient fuel formulation for diesel engine. | Peng Zhang Xin Su Chengshan Yi Hao Chen Hongming Xu Limin Geng | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，3： | 2 |
| 18 | A progress review on methods for in vivo measurement of ^(131)I in thyroids by using portable gamma spectrometers显示文摘Iodine-131 is a highly toxic and volatile artificial radionuclide that is easily inhaled or ingested by the human body and selectively accumulates in thyroid tissue.With the development of nuclear medicine and nuclear power plants,the unintended release of ^(131)I has been widely studied,and the in vivo measurement of ^(131)I in the thyroid has become a research hotspot in the field of radiation protection.In recent decades,several methods and devices have been developed for in vivo measurements with respect to different measurement purposes and requirements.In this work,for more accurate determinations of individual ^(131)I in the thyroid in the field,the uncertainties of measurements by using portable gamma spectrometers were reviewed and analyzed,and monitoring strategies for improving the accuracy were proposed and prospected. | Hongming Liu Bo Chen Weihai Zhuo | 2021 | Radiation Medicine and Protection2021，2，4： | 2 |
| 19 | Corrosion formation and phase transformation of nickel-iron hydroxide nanosheets array for efficient water oxidation显示文摘Designing earth-abundant electrocatalysts with high performance towards water oxidation is highly decisive for the sustainable energy technologies. This study develops a facile natural corrosion approach to fabricate nickel-iron hydroxides for water oxidation. The resulted electrode demonstrates an outstanding activity and stability with an overpotential of 275 mV to deliver 10 mA·cm^(−2). Experimental and theoretical results suggest the corrosion-induced formation of hydroxides and their transformation to oxyhydroxides would account for this excellent performance. This work not only provides an interesting corrosion approach for the fabrication of excellent water oxidation electrode, but also bridges traditional corrosion engineering and novel materials fabrication, which would offer some insights in the innovative principles for nanomaterials and energy technologies. | Lanqian Gong Huan Yang Hongming Wang Ruijuan Qi Junlei Wang Shenghua Chen Bo You Zehua Dong Hongfang Liu Bao Yu Xia | 2021 | Nano Research2021，14，12： | 2 |
| 20 | Nutritional evaluation of whole soybean curd made from different soybean materials based on amino acid profiles显示文摘Objectives:Amino acid profiles of whole soybean curds(WSCs)and conventional soybean curds(CSCs)were comparatively studied to 1.,evaluate their nutritional value and 2.,study the suitable soybean material to fabricate WSCs.Materials and Methods:Nine types of soybean materials were selected to make WSCs and CSCs.Protein digestibility-corrected amino acid score(PDCAAS)and principal component analysis were selected to perform the comparative analysis of amino acid profiles of the products.Results:Total contents of amino acids in WSCs and CSCs were 41.24-54.87 mg/g and 27.77-36.82 mg/g.Content ranges of essential amino acids were 13.59-19.38 mg/g and 8.46-11.76 mg/g for WSCs and CSCs.The essential amino acid pattern of WSCs was basically close to amino acid pattern spectrum requirements except valine and sulfur amino acids.As a limiting amino acid,methionine represented less than 0.4 for PDCAAS in all soybean curds except WSCs made from relay-cropping Nandou12 and Nandou25.Conclusions:The overall quality of amino acids in WSCs was higher than that in CSCs,indicating that WSCs indeed exhibited higher nutritional value than CSCs from the viewpoint of amino acid profile.WSCs with the high nutritional value could be made using Nandou25 and relay-cropping Nandou12 as materials. | Meili Li Hongming Dong Dingtao Wu Hong Chen Wen Qin Weiguo Liu Wenyu Yang Qing Zhang | 2020 | Food Quality and Safety2020，4，1： | 2 |
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