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| 1 | Towards 6G wireless communication networks:vision,enabling technologies,and new paradigm shifts显示文摘The fifth generation(5G)wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized,such as mass connectivity,ultra-reliability,and guaranteed low latency.However,5G will not meet all requirements of the future in 2030 and beyond,and sixth generation(6G)wireless communication networks are expected to provide global coverage,enhanced spectral/energy/cost efficiency,better intelligence level and security,etc.To meet these requirements,6G networks will rely on new enabling technologies,i.e.,air interface and transmission technologies and novel network architecture,such as waveform design,multiple access,channel coding schemes,multi-antenna technologies,network slicing,cell-free architecture,and cloud/fog/edge computing.Our vision on 6G is that it will have four new paradigm shifts.First,to satisfy the requirement of global coverage,6G will not be limited to terrestrial communication networks,which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle(UAV)communication networks,thus achieving a space-airground-sea integrated communication network.Second,all spectra will be fully explored to further increase data rates and connection density,including the sub-6GHz,millimeter wave(mmWave),terahertz(THz),and optical frequency bands.Third,facing the big datasets generated by the use of extremely heterogeneous networks,diverse communication scenarios,large numbers of antennas,wide bandwidths,and new service requirements,6G networks will enable a new range of smart applications with the aid of artificial intelligence(AI)and big data technologies.Fourth,network security will have to be strengthened when developing 6G networks.This article provides a comprehensive survey of recent advances and future trends in these four aspects.Clearly,6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears. | Xiaohu YOU Cheng-Xiang WANG Jie HUANG Xiqi GAO Zaichen ZHANG Mao WANG Yongming HUANG Chuan ZHANG Yanxiang JIANG Jiaheng WANG Min ZHU Bin SHENG Dongming WANG Zhiwen PAN Pengcheng ZHU Yang YANG Zening LIU Ping ZHANG Xiaofeng TAO Shaoqian LI Zhi CHEN Xinying MA Chih-Lin I Shuangfeng HAN Ke LI Chengkang PAN Zhimin ZHENG Lajos HANZO Xuemin(Sherman)SHEN Yingjie Jay GUO Zhiguo DING Harald HAAS Wen TONG Peiying ZHU Ganghua YANG Jun WANG Erik GLARSSON Hien Quoc NGO Wei HONG Haiming WANG Debin HOU Jixin CHEN Zhe CHEN Zhangcheng HAO Geoffrey Ye LI Rahim TAFAZOLLI Yue GAO HVincent POOR Gerhard P.FETTWEIS Ying-Chang LIANG | 2021 | Science China(Information Sciences)2021，64，1： | 122 |
| 2 | Variations of shear wave splitting in the 2008 Wenchuan earthquake region显示文摘Through the analysis of S-wave particle motion of local events in the shear wave window, the polariza-tion directions of the faster shear wave and the delay times between the faster and the slower shear waves were derived from seismic recordings at the stations near the fault zones. The shear wave split-ting results of seven stations in the area of Longmenshan fault zone reveal spatial variation of the po-larization directions of the fast shear wave. The directions at stations in the southeastern side of the Longmenshan fault zone (in the Sichuan Basin area) are in the NE direction, whereas the direction at station PWU (in the Plateau), which is in the northwestern side of the faults, is in the EW direction. Systematic changes of the time delays between two split shear waves were also observed. At station L5501 in the southern end of the aftershock zone, the delay times of the slower shear wave decrease systematically after the main shock. After the main shock, the delay times at station PWU were longer than those before the earthquake. Seismic shear wave splitting is caused mostly by stress-aligned microcracks in the rock below the stations. The results demonstrate changes of local stress field dur-ing the main-shock and the aftershocks. The stress in the southern part of Wenchuan seismogenic zone was released by the main-shock and the aftershocks. The crustal stresses were transferred to the northeastern part of the zone, resulting in stress increase at station PWU after the main-shock. | DING ZhiFeng WU Yan WANG Hui ZHOU XiaoFeng LI GuiYin | 2008 | Science China Earth Sciences2008，51，12： | 18 |
| 3 | Epigenetic Modifications of mRNA and DNA in Plants显示文摘Advances in the detection and mapping of messenger RNA(mRNA)N^6-methyladenosine(m 6A)and 5-methylcytosine(m 5C),and DNA N^6-methyldeoxyadenosine(6mA)redefined our understanding of these modifications as additional tiers of epigenetic regulation.In plants,the most prevalent internal mRNA modifications,m^6A and m^5C,play crucial and dynamic roles in many processes,including embryo development,stem cell fate determination,trichome branching,leaf morphogenesis,floral transition,stress responses,fruit ripening,and root development.The newly identified and widespread epigenetic marker 6mA DNA methylation is associated with gene expression,plant development,and stress responses.Here,we review the latest research progress on mRNA and DNA epigenetic modifications,including the detection,dynamics,distribution,functions,regulatory proteins,and evolution,with a focus on m^6A,m^5C,and 6mA.We also provide some perspectives on future research of the newly identified and unknown epigenetic modifications of mRNA and DNA in plants. | Zhe Liang Adeel Riaz Sadaruddin Chachar Yike Ding Hai Du Xiaofeng Gu | 2020 | Molecular Plant2020，13，1： | 12 |
| 4 | Tomographic imaging of P wave velocity structure beneath the region around Beijing显示文摘The three-dimension crustal and upper mantle structures in the region around Beijing were studied by seismic tomography. We used the P wave arrival times from local and teleseismic events. These events were recorded by 250 stations of the North China Seismic Array and 108 stations of the Beijing Telemetry Seismic Network. 118 869 P wave arrivals from 10 285 local events and 12 189 P wave arrivals from 107 teleseismic events were used in the inversion. We obtained the 3-D P wave velocity structure of the crust and upper mantle with the horizontal resolution of 0.3° in the studied region. The tomographic imaging shows the remarkably heterogeneous velocity variation. The velocity anomalies are in well agreement with the geological structure in the shallow crust. The different relationships between seismic activities and velocity anomalies may imply the different seismogenic structure and mechanism. Beneath the Moho under Taihangshan mountain and Yanshan mountain,we found the high velocity anomalies deep to 120 km and 200 km,respectively. The deep high velocity zone may be explained by the existence of the mountain root under Yanshan mountain. The high velocity anomalies in the upper mantle of North China basin may be the relics of the de-rooting from the former craton mantle lithosphere. | Zhifeng Ding Xiaofeng Zhou Yan Wu Guiyin Li Hong Zhang | 2009 | Earthquake Science2009，22，4： | 10 |
| 5 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 6 | Development of a new method for analyzing free aluminum ions(Al^(3+)) in seafood using HPLC-ICP-MS显示文摘This paper presents a novel method for simultaneous online examination of free aluminum ions(Al3+)in seafood,using solidphase extraction and high-performance liquid chromatography online with inductively coupled plasma mass spectrometry(SPEHPLC-ICP-MS),without post-column reaction.The optimum conditions for chromatographic separation of Al3+were achieved using an IonPac CS5A analytical column with an IonPac CG5A guard column.The mobile phase consisted of 0.040 mol/L LiOH,0.0060 mol/L 2,6-pyridinedicarboxylic acid,and 0.090 mol/L CH3COOH(pH 4.7).The free Al3+ions in seafood were extracted by shaking with the mobile phase at 70°C for 2 h.SPE was conducted using an Oasis MCX,3cc/60 mg,30μm column,which was activated and equilibrated with 2 mL of methanol and 4 mL of deionized water before use.HCl(0.075 mol/L,2 mL)was used to wash inorganic Al from the SPE column.The standard recoveries of Al3+were all above 89%and the relative standard deviations were all below 5%.The proposed method was successfully used for the examination of Al3+in seafood samples,and the results were similar to those obtained using the static equilibrium method. | SHANG DeRong ZHAO YanFang ZHAI YuXiu NING JinSong DING HaiYan SHENG XiaoFeng | 2013 | Chinese Science Bulletin2013，58，35： | 8 |
| 7 | 3D Lamellar-Structured Graphene Aerogels for Thermal Interface Composites with High Through-Plane Thermal Conductivity and Fracture Toughness显示文摘Although thermally conductive graphene sheets are efficient in enhancing in-plane thermal conductivities of polymers,the resulting nanocomposites usually exhibit low through-plane thermal conductivities,limiting their application as thermal interface materials.Herein,lamellarstructured polyamic acid salt/graphene oxide(PAAS/GO)hybrid aerogels are constructed by bidirectional freezing of PAAS/GO suspension followed by lyophilization.Subsequently,PAAS monomers are polymerized to polyimide(PI),while GO is converted to thermally reduced graphene oxide(RGO)during thermal annealing at 300℃.Final graphitization at 2800℃ converts PI to graphitized carbon with the inductive effect of RGO,and simultaneously,RGO is thermally reduced and healed to high-quality graphene.Consequently,lamellar-structured graphene aerogels with superior through-plane thermal conduction capacity are fabricated for the first time,and its superior through-plane thermal conduction capacity results from its vertically aligned and closely stacked high-quality graphene lamellae.After vacuum-assisted impregnation with epoxy,the resultant epoxy composite with 2.30 vol% of graphene exhibits an outstanding through-plane thermal conductivity of as high as 20.0 W m^−1 K^−1,100 times of that of epoxy,with a record-high specific thermal conductivity enhancement of 4310%.Furthermore,the lamellar-structured graphene aerogel endows epoxy with a high fracture toughness,~1.71 times of that of epoxy. | Pengfei Liu Xiaofeng Li Peng Min Xiyuan Chang Chao Shu Yun Ding Zhong-Zhen Yu | 2021 | Nano-Micro Letters2021，13，2： | 7 |
| 8 | Suppression of multiple modal resonances of a cantilever beam by an impact damper显示文摘Impact dampers are usually used to suppress single mode resonance. The goal of this paper is to clarify the difference when the impact damper suppresses the resonances of different modes. A cantilever beam equipped with the impact damper is modeled. The elastic contact of the ball and the cantilever beam is described by using the Hertz contact model. The viscous damper between the ball and the cantilever beam is modeled to consume the vibrational energy of the cantilever beam. A piecewise ordinary differential-partial differential equation of the cantilever beam is established, including equations with and without the impact damper. The vibration responses of the cantilever beam with and without the impact damper are numerically calculated. The effects of the impact absorber parameters on the vibration reduction are examined. The results show that multiple resonance peaks of the cantilever beam can be effectively suppressed by the impact damper. Specifically, all resonance amplitudes can be reduced by a larger weight ball. Moreover, the impacting gap is very effective in suppressing the vibration of the cantilever beam. More importantly, there is an optimal impacting gap for each resonance mode of the cantilever beam, but the optimal gap for each mode is different. | Xiaofeng GENG Hu DING Kexiang WEI Liqun CHEN | 2020 | Applied Mathematics and Mechanics(English Edition)2020，41，3： | 5 |
| 9 | NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc显示文摘Background:Cisplatin-based chemotherapy with concurrent radiotherapy is a standard treatment for advanced esophageal squamous cell carcinoma(ESCC).NS1-binding protein(NS1-BP),a member of the BTB-kelch protein fam-ily,has been shown to inhibit the proliferation of Hela cells by suppressing c-Myc.In the present study,we examined the potential function role of NS1-BP expression in ESCC,and particularly,the sensitivity of ESCC to radiotherapy.Methods:NS1-BP expression was examined using immunohistochemistry in two cohorts(n=98 for the training cohort;n=46 for independent validation cohort)of ESCC patients receiving cisplatin-based chemotherapy and con-current radiotherapy.Normal esophageal mucosal tissue blocks were used as a control.We also conducted a series of in vitro and in vivo experiments to examine the potential effects of over-expressing NS1-BP on ESCC cells,and particu-larly their sensitivity to ionizing irradiation.Results:In the training cohort,NS1-BP downregulation was observed in 59%(85/144)of the ESCC specimens.NS1-BP downregulation was associated with chemoradiotherapeutic resistance and shorter disease-specific survival(DSS)in both the training and validation cohorts.Over-expressing NS1-BP in cultured ESCC cells substantially increased the cellular response to irradiation both in vitro and in vivo.NS1-BP also significantly enhanced IR-induced apoptosis,and abrogated IR-induced G2/M cell-cycle arrest and ATM/Chk1 phosphorylation.Immunoprecipitation assays indicated that NS1-BP could interact with c-Myc promoter regions to inhibit its transcription.In ESCC tissues,c-Myc expression was inversely correlated with NS1-BP levels,and was associated with a shorter DSS.Conclusions:Our findings highlight the role and importance of NS1-BP in radiosensitivity of ESCC.Targeting the NS1-BP/c-Myc pathway may provide a novel therapeutic strategy for ESCC. | Yuwen Wang Jingjing Cheng Dan Xie Xiaofeng Ding Hailing Hou Xi Chen Puchun Er Furong Zhang Lujun Zhao Zhiyong Yuan Qingsong Pang Ping Wang Dong Qian | 2018 | Cancer Communications2018，38，1： | 4 |
| 10 | Correlations of PCBs, DIOXIN, and PBDE with TSH in Children's Blood in Areas of Computer E-waste Recycling显示文摘Objective To study correlations of polychlorinated biphenyls (PCBs), DIOXIN, and polybrominated diphenyl ethers (PBDE) with thyroid stimulating hormone(TSH) in children, and assess the impact on children's health. Methods Three hundred and sixty nine children aged from 6 to 8, including 195 from Luqiao, the computer E‐waste recycling area, and 174 from Longyou, the control area, were selected for this investigation to elucidate the correlation of PCBs, DIOXIN, and PBDE with TSH in children's blood samples. The children had a physical examination and their blood levels of PCBs, DIOXIN, PBDE, and TSH were detected after sample collection. Results In the E‐waste recycling area, the contents of PCBs, PBDE, DIOXIN, and TSH in the blood samples of children were 484.00±84.86 ng·g ‐1 lipid weight, 664.28±262.38 ng·g ‐1 lipid weight, 26.00±19.58 ng·g ‐1 lipid weight and 1.88±0.42 μIU/mL (serum) respectively, while in the control area, the PCBs, PBDE, DIOXIN, and TSH contents were 255.38±95 ng·g ‐1 lipid weight, 375.81±262.43 ng·g ‐1 lipid weight, 39.64±31.86 ng·g ‐1 lipid weight, and 3.31±1.04 μIU/mL respectively. Conclusion The health status of children in the control area are better than that in the contaminated area. Among children who are exposed to persistent organic pollutants, the pollutant content increases significantly in their serum, and the distribution of TSH levels in their bodies are also affected. | HAN GuanGen DING GangQiang LOU XiaoMing WANG XiaoFeng HAN JianLong SHEN HaiTao ZHOU Yu DU LeYan | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 11 | KCTDIO is critical for heart and blood vessel development of zebrafish显示文摘 | Xiang Hu Shiquan Gan Guie Xie Li Li Cheng Chen Xiaofeng Ding Mei Han Shuanglin Xiang Jian Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 4 |
| 12 | Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors显示文摘Normal cells become cancer cells after a malignant transformation,but whether cancer cells can be reversed to normal status remains elusive.Here,we report that the combination of hepatocyte nuclear factor IA (HNFIA),HNF4A and forkhead box protein A3 (FOXA3)synergistically reprograms hepatocellular carcinoma (HCC)cells to hepatocyte-like cells (reprogrammed hepatocytes, rHeps).Our results show that rHeps lose the malignant phenotypes of cancer cells and retrieve hepatocyte-specific characteristics including hepatocyte-like morphology;global expression pattern of genes and specific biomarkers of hepatocytes;and the unique hepatic functions of albumin (ALB)secretion,glycogen synthesis,low-density lipoprotein (LDL)uptake,urea production, cytochrome P450 enzymes induction and drug metabolism.Intratumoral injection of these three factors efficiently shrank patientderived tumor xenografts and reprogrammed HCC cells in vivo.Most importantly,transplantation of rHeps in the liver of fumarylacetoacetate hydrolase-deficient (Fah^-/-)mice led to the reconstruction of hepatic lobules and the restoration of hepatic function.Mechanistically,exogenous expression of HNF1A,HNF4A and FOXA3 in HCC cells initiated the endogenous expression of numerous hepatocyte nuclear factors,which promoted the conversion of HCC cells to hepatocyte-like cells.Collectively,our results indicate the successful conversion of hepatoma cells to hepatocyte-like cells,not only extending our current knowledge of cell reprogramming but also providing a route towards a novel therapeutic strategy for cancer. | Zhuo Cheng Zhiying He Yongchao Cai Cheng Zhang Gongbo Fu Hengyu Li Wen Sun Changcheng Liu Xiuliang Cui Beifang Ning Daimin Xiang Tengfei Zhou Xiaofeng Li Weifen Xie Hongyang Wang Jin Ding | 2019 | Cell Research2019，29，2： | 3 |
| 13 | Wave parameters retrieval for dual-polarization C-band synthetic aperture radar using a theoretical-based algorithm under cyclonic conditions显示文摘Theoretical-based ocean wave retrieval algorithms are applied by inverting a synthetic aperture radar(SAR)intensity spectrum into a wave spectrum, that has been developed based on a SAR wave mapping mechanism. In our previous studies, it was shown that the wave retrieval algorithm, named the parameterized first-guess spectrum method(PFSM), works for C-band and X-band SAR at low to moderate sea states. In this work, we investigate the performance of the PFSM algorithm when it is applied for dual-polarization c-band sentinel-1(S-1) SAR acquired in extra wide-swath(EW) and interferometric wide-swath(IW) mode under cyclonic conditions.Strong winds are retrieved from six vertical-horizontal(VH) polarization S-1 SAR images using the c-band crosspolarization coupled-parameters ocean(C-3 PO) model and then wave parameters are obtained from the image at the vertical-vertical(VV) polarization channel. significant wave height(SWH) and mean wave period(MWP) are compared with simulations from the WAVEWATCH-III(WW3) model. The validation shows a 0.69 m root mean square error(RMSE) of SWH with a –0.01 m bias and a 0.62 s RMSE of MWP with a –0.17 s bias. Although the PFSM algorithm relies on a good quality SAR spectrum, this study confirms the applicability for wave retrieval from an S-1 SAR image. Moreover, it is found that the retrieved results have less accuracy on the right sector of cyclone eyes where swell directly affects strong wind-sea, while the PFSM algorithm works well on the left and rear sectors of cyclone eyes where the interaction of wind-sea and swell is relatively poor. | Yingying Ding Juncheng Zuo Weizeng Shao Jian Shi Xinzhe Yuan Jian Sun Jiachen Hu Xiaofeng Li | 2019 | Acta Oceanologica Sinica2019，38，5： | 3 |
| 14 | Human ZCCHC12 activates AP-1 and CREB signaling as a transcriptional co-activator显示文摘包含 12 基因(ZCCHC12 ) 的老鼠锌手指 CCHC 领域作为骨头的 transcriptional 激活剂被识别了发信号的形态基因的蛋白质(BMP ) ,和人的 ZCCHC12 被报导与 non-syndromic X 连接智力迟钝(NS-XLMR ) 有关。然而,的细节人的 ZCCHC12 在 NS-XLMR 包含仍然保持不清楚。在这研究,我们在为原子本地化负责的人的 ZCCHC12 蛋白质的中间识别了一个新奇原子本地化信号(NLS ) 。多重织物的北污点分析显示 ZCCHC12 高度在人的大脑被表示。而且,在 situ,杂交证明 ZCCHC12 明确地在老鼠 E10.5 胚胎的前脑,中脑,和间脑区域的 neuroepithelium 被表示。酶记者试金证明 ZCCHC12 作为激活剂提高了使活跃之物蛋白质 1 的 transcriptional 活动(AP-1 ) 和营地反应元素绑定蛋白质(CREB ) 。在结论,我们在 ZCCHC12 识别了新 NLS 并且弄明白 ZCCHC12 作为 AP-1 和 CREB 的 transcriptional 激活剂工作。 | Hong Li Qian Liu Xiang Hu Du Feng Shuanglin Xiang Zhicheng He Xingwang Hu Jianlin Zhou Xiaofeng Ding Chang Zhou Jian Zhang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 3 |
| 15 | Phosphorus release from cyanobacterial blooms in Meiliang Bay of Lake Taihu, China显示文摘 | Xiaoming Chuai Wei Ding Xiaofeng Chen Xiaolin Wang Aijun Miao Beidou Xi Lianshen He Liuyan Yang | 2011 | Ecological Engineering2011，，6： | 3 |
| 16 | NS1结合蛋白通过转录抑制c-Myc增强食管鳞状细胞癌的放疗敏感性显示文摘背景与目的基于顺铂的化疗联合放疗是晚期食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)的标准疗法。NS1结合蛋白(NS1-binding protein,NS1-BP)是BTB-kelch蛋白家族中的一员,已被证明可通过抑制c-Myc进而抑制HeLa细胞增殖。在本研究中,我们检测NS1-BP表达在ESCC中的潜在作用,特别是其在ESCC放疗敏感性方面的作用。方法对于两组接受基于顺铂化疗且联合放疗的ESCC患者(研究组n=98;验证组n=46),采用免疫组化方法分别检测NS1-BP表达。使用正常食管黏膜组织块作为对照。我们也进行了一系列体外和体内实验来检测过表达NS1-BP对ESCC细胞各方面的潜在影响,尤其关注的是对电离辐射的敏感性方面的影响。结果在研究组中,59%(85/144)的ESCC样本观察到了NS1-BP下调。在研究组和验证组中,NS1-BP下调与放化疗抵抗和较短的疾病特异生存期(disease-specific survival,DSS)均具有相关性。体内和体外培养条件下过表达NS1-BP均能大幅度提高ECSS细胞对放疗的敏感性。NS1-BP也显著增强IR诱导的凋亡,阻断IR诱导的G2/M细胞周期阻滞和ATM/Chk1磷酸化。免疫沉淀反应显示NS1-BP可以与c-Myc启动子区相互作用从而抑制其转录。在ESCC组织中,c-Myc表达与NS1-BP水平负相关,与较短的疾病特异生存期相关。结论我们的研究结果显示了NS1-BP在ESCC放疗敏感性中的作用和重要性。以NS1-BP/c-Myc通路为靶标有望开发一种新的ESCC治疗策略。 | Yuwen Wang Jingjing Cheng Dan Xie Xiaofeng Ding Hailing Hou Xi Chen Puchun Er Furong Zhang Lujun Zhao Zhiyong Yuan Qingsong Pang Ping Wang Dong Qian | 2019 | 癌症2019，38，2： | 2 |
| 17 | Zwitterionic glycine modified Fe/Mg-layered double hydroxides for highly selective and efficient removal of oxyanions from polluted water显示文摘Zwitterionic glycine was employed to modify Fe/Mg-layered double hydroxides(LDH)to realize an GFe/Mg-LDH adsorbent with high adsorption capacities of oxygen-containing anions including As(Ⅴ),P(Ⅴ)and Cr(Ⅵ).When the Fe/Mg mole ratio was 0.02 mol/0.02 mol,the G-Fe/Mg-LDH has a good adsorption performance.The optimum adsorption pH value of G-Fe/Mg-LDH for oxygen-containing anions was 6.The selectivity of three oxygen-containing anions was Cr(Ⅵ) | Xiaofeng Shi Chao Wang Jiaoxia Zhang Li Guo Jing Lin Duo Pan Juying Zhou Jincheng Fan Tao Ding Zhanhu Guo | 2020 | Journal of Materials Science & Technology2020，47，16： | 2 |
| 18 | Modeling,analysis,and simulation of X-shape quasi-zero-stiffness-roller vibration isolators显示文摘Existing quasi-zero stiffness(QZS)isolators are reviewed.In terms of their advantages,a novel X-shape QZS isolator combined with the cam-roller-spring mechanism(CRSM)is proposed.Different from the existing X-shape isolators,oblique springs are used to enhance the negative stiffness of the system.Meanwhile,the CRSM is used to eliminate the gravity of the loading mass,while the X-shape structure leaves its static position.The existing QZS isolators are demonstrated and classified according to their nonlinearity mechanisms and classical shapes.It is shown that the oblique spring can realize negative stiffness based on the simplest mechanism.The X-shape has a strong capacity of loading mass,while the CRSM can achieve a designed restoring force at any position.The proposed isolator combines all these advantages together.Based on the harmonic balance method(HBM)and the simulation,the displacement transmissibilities of the proposed isolator,the X-shape isolators just with oblique springs,and the X-shape isolators in the traditional form are studied.The results show that the proposed isolator has the lowest beginning isolation frequency and the smallest maximum displacement transmissibility.However,it still has some disadvantages similar to the existing QZS isolators.This means that its parameters should be designed carefully so as to avoid becoming a bistable system,in which there are two potential wells in the potential energy curve and thus the isolation performance will be worsened. | Xiaoye MAO Mengmeng YIN Hu DING Xiaofeng GENG Yongjun SHEN Liqun CHEN | 2022 | Applied Mathematics and Mechanics(English Edition)2022，43，7： | 2 |
| 19 | Correlation of obstructive sleep apnea hypopnea syndrome with metabolic syndrome in snorers显示文摘Though obstructive sleep apnea hypopnea syndrome(OSAHS) and metabolic syndrome(MS) are correlated;the contributing factors for the occurrence of MS in Chinese snorers remain largely undefined.We aimed to investigate the associated pathogenesis of coexistence of OSAHS and MS in Chinese snorers.A total of 144 Chinese habitual snorers were divided into 3 groups,the control group(simple snorers)(n = 36),the mild OSAHS group(n= 52)and the moderate-to-severe OSAHS group(n = 56).The incidence of MS in the moderate-to-severe OSAHS group(26.8%) was significantly higher than that in the control group(8.3%),the mild OSAHS group(11.1%) and all the OSAHS patients(19.45%)(all P < 0.05).Homeostatic model assessment(HOMA) index and proinsulin(PI) were negatively correlated with nocturnal meanSpO_2 and miniSpO_2.Meanwhile,nocturnal SpO_2 were negatively correlated with body mass index,waist and neck circumferences and diastolic blood pressure,but positively correlated with total cholesterol and high-density lipoprotein cholesterol.The study indicated that in Chinese snorers,moderate-to-severe OSAHS was closely associated with MS via nocturnal hypoxemia. | Qun Zhang Xiaofeng Zhang Mengmeng Zhao Hanpeng Huang Ning Ding Xilong Zhang Hong Wang | 2014 | The Journal of Biomedical Research2014，28，3： | 2 |
| 20 | Rice In Vivo RNA Structurome Reveals RNA Secondary Structure Conservation and Divergence in Plants显示文摘RNA 第二等的结构在基因规定起一个关键作用。瑞斯(Oryza sativa ) 是在世界上的最重要的食物庄稼之一。然而,在米饭的 RNA 结构几乎没被学习。这里,我们成功地产生了在 ? 在米饭的 vivo Structure-seq 图书馆。我们发现 mRNAs 的结构的灵活性可能与生物功能的动力学联系。更高的 N 6-methyladenosine (m 6 一) 修正趋于在 3 UTR 有更少的 RNA 结构,而 GC 内容显著地不影响在 ? 维持象翻译那样的有效生物过程的 vivo mRNA 结构。在米饭和 Arabidopsis 之间的 RNA structurome 的比较分析揭示了内容不导致的那更高的 GC 更强壮的结构和更少 RNA 结构的灵活性。而且,我们发现了在顺序和在米饭和 Arabidopsis 之间的 orthologs 的结构保存之间的弱关联。顺序并且在的保存和分叉 ? vivo RNA 结构对应于多样、特定的生物过程。我们的结果显示那 RNA 第二等的结构可能把选择的分开的层提供给在 monocot 和 dicot 之间的顺序。因此,我们的学习暗示那 RNA 结构在各种各样的生物进程不同地演变在被子植物进化期间在开发和 adaptational 灵活性维持坚韧性。 | Hongjing Deng Jitender Cheema Hang Zhang Hugh Woolfenden Matthew Norris Zhenshan Liu Qi Liu Xiaofei Yang Minglei Yang Xian Deng Xiaofeng Cao Yiliang Ding | 2018 | Molecular Plant2018，11，4： | 2 |
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