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| 1 | ZmMs30 Encoding a Novel GDSL Lipase Is Essential for Male Fertility and Valuable for Hybrid Breeding in Maize显示文摘Genic male sterility (GMS) is very useful for hybrid vigor utilization and hybrid seed production. Although a large number of GMS genes have been identified in plants, little is known about the roles of GDSL lipase members in anther and pollen development. Here, we report a maize GMS gene, ZmMs30, which encodes a novel type of GDSL lipase with diverged catalytic residues. Enzyme kinetics and activity assays show that ZmMs30 has lipase activity and prefers to substrates with a short carbon chain. ZmMs30 is specifically expressed in maize anthers during stages 7-9. Loss of ZmMs30 function resulted in defective anther cuticle, irregular foot layer of pollen exine, and complete male sterility. Cytological and lipidomics analyses demonstrate that ZmMs30 is crucial for the aliphatic metabolic pathway required for pollen exine formation and anther cuticle development. Furthermore, we found that male sterility caused by loss of ZmMs30 function was stable in various inbred lines with different genetic background, and that it didn't show any negative effect on maize heterosis and production, suggesting that ZmMs30 is valuable for crossbreeding and hybrid seed production. We then developed a new multi-control sterility system using ZmMs30 and its mutant line, and demonstrated it is feasible for generating desirable GMS lines and valu. able for hybrid maize seed production. Taken together, our study sheds new light on the mechanisms of anther and pollen development, and provides a valuable male-sterility system for hybrid breeding maize. | Xueli An Zhenying Dong Youhui Tian Ke Xie Suowei Wu Taotao Zhu Danfeng Zhang Van Zhou Canfang Niu Biao Ma Quancan Hou Jianxi Bao Simiao Zhang Ziwen Li Yanbo Wang Tingwei Yan Xiaojing Sun Yuwen Zhang Jinping Li Xiangyuan Wan | 2019 | Molecular Plant2019，12，3： | 15 |
| 2 | An overview of design for CSNS/RCS and beam transport显示文摘The China Spallation Neutron Source (CSNS) is the first accelerator-based pulsed neutron source in China. Its accelerators are made up of an 80 MeV H- linac, a Rapid Cycling Synchrotron (RCS) and two beam transport lines. RCS accumulates and accelerates protons to the design energy of 1.6 GeV, and extracts high energy beam to strike the target. The overview of RCS is presented, and the key problems of the physics design are discussed. The two beam transport lines, from linac to RCS and from RCS to the target, are also introduced. | WANG Sheng AN YuWen FANG ShouXian HUANG Nan LIU WeiBin LIU YuDong QIN Qing QIU Jing WANG Na XU Gang XU ShouYan YU ChengHui | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 11 |
| 3 | Concentrations and gas-particle partitioning of PCDD/Fs in the urban air of Dalian,China显示文摘PCDD/Fs in the urban air of Dalian,China were monitored with high-volume active sampler from November 2009 to October 2010.The concentration of Cl 4-8 DD/Fs ranged from 3065 to 49538 fg m-3,with an average of 10249 fg m-3.The international toxic equivalents(I-TEQ) value of that was 61.8 1182 fg m-3,with an average of 235 fg m-3,which was comparable to those in the other urban locations around the world.It was found that the Cl 4 8 DD/Fs appeared to be present mainly in the particle phase during winter,spring and autumn,while during summer which were dominantly in gas phase.The ratio of Cl 4-8 DD/Fs present in particle phase increased with the increasing level of chlorination.The concentrations of PCDFs and PCDDs decreased with the increase of chlorinated level,while the concentrations of 2,3,7,8-PCDDs congeners increased with the increase of chlorination level.The homolog profiles of the concentrations of PCDFs presented were higher than those of the PCDDs,which indicated the PCDD/Fs pollution source of the air in Dalian was characteristic for thermal source pollution.The correlation analysis of meteorological parameters with the concentrations of Cl 4-8 CDD/Fs was conducted using SPSS packages,and it was found that the ambient temperature and atmospheric pressure were important factors influence the concentration of PCDD/Fs in the air.The respiratory risk and intake dioxins of the residents around the sampling sites were studied in the paper.It was found that Junge-Pankow model was much more accurate in predicting the gas-particle partitioning behavior of PCDD/Fs homologues during winter,while the Harner-Bidleman model shows better agreement with the measured data during winter and summer. | QIN SongTao ZHU XiuHua WANG Wei CHEN JiPing NI YuWen LI XiaoXiao MU Jun Xu Qian SCHRAMM Karl-Werner | 2012 | Chinese Science Bulletin2012，57，26： | 10 |
| 4 | Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders显示文摘Human genetic adaptation to high altitudes(>2500 m)has been extensively studied over the last few years,but few functional adaptive genetic variants have been identified,largely owing to the lack of deep-genome sequencing data available to previous studies.Here,w e build a list of putative adaptive variants,including 63 missense,7 loss-of-function;1,298 evolutionarily conserved variants and 509 expression quantitative traits loci.Notably,the top signal of selection is located in TMEM 247,a transmembrane protein-coding gene.The Tibetan version of TMEM 247 harbors one high-frequency(76.3%)missense variant,rsl 16983452(c.248C>T;p.Ala83Val);with the T allele derived from archaic ancestry and carried by>94%of Tibetans but absent or in low frequencies(<3%)in non-Tibetan populations.The rsl 16983452-T is strongly and positively correlated with altitude and significantly associated with reduced hemoglobin concentration(p=5.78×10^-5),red blood cell count(p=5.72×10^-7)and hematocrit(p=2.57×10^-6).In particular,TMEM247-rs 116983452 shows greater effect size and better predicts the phenotypic outcome than any E P A S1 variants in association with adaptive traits in Tibetans.Modeling the interaction between TM£M247-rsl 16983452 and EPAS1 variants indicates weak but statistically significant epistatic effects.Our results support that multiple variants may jointly deliver the fitness of the Tibetans on the plateau,where a complex model is needed to elucidate the adaptive evolution mechanism. | Lian Deng Chao Zhang Kai Yuan Yang Gao Yuwen Pan Xueling Ge Yaoxi He Yuan Yuan Yan Lu Xiaoxi Zhang Hao Chen Haiyi Lou Xiaoji Wang Dongsheng Lu Jiaojiao Liu Lei Tian Qidi Feng Asifullah Khan Yajun Yang Zi-Bing Jin Jian Yang Fan Lu Jia Qu Longli Kang Bing Su Shuhua Xu | 2019 | National Science Review2019，6，6： | 9 |
| 5 | Simultaneous monitoring of PCB profiles in the urban air of Dalian,China with active and passive samplings显示文摘The concentration of polychlorinated biphenyls (PCBs) in the urban air of Dalian, China was monitored from November 2009 to October 2010 with active high-volume sampler and semipermeable membrane device (SPMD) passive sampler. The concentration of PCBs (particle + gas) ( ∑ PCBs) ranged from 18.6 to 91.0 pg/m 3 , with an average of 50.9 pg/m 3 , and the most abundant dioxin-like PCB (DL-PCBs) was PCB118. The WHO-TEQ values of DL-PCBs were 3.6-22.1 fg/m3 , with an average of 8.5 fg/m 3 , and PCB126 was the maximum contributor to ∑ TEQ. There was a much larger amount of PCBs in the gas phase than in the particulate phase. The dominant PCB components were lower and middle molecular weight PCBs. With increasing chlorination level, the concentration of the PCB congeners in the air decreased. The gas-particulate partitioning of PCBs was different for the four seasons. The gas- particulate partitioning coefficients (logK p ) vs. subcooled liquid vapor pressures (logP L 0 ) of PCBs had reasonable correlations for different sampling sites and seasons. The absorption mechanism contributed more to the gas-particulate partitioning process than adsorption. Correlation analysis of meteorological parameters with the concentration of PCBs was conducted using SPSS packages. The ambient temperature and atmospheric pressure were important factors influencing the concentration of PCBs in the air. The distribution pattern of the congeners of PCBs and the dominant contributors to DL-PCBs and TEQ in active samples and SPMDs passive samples were similar. SPMD mainly sequestrated gas phase PCBs. | Qian Xu Xiuhua Zhu Bernhard Henkelmann Karl-Werner Schramm Jiping Chen Yuwen Ni Wei Wang Gerd Pfister Jun Mu Songtao Qin Yan Li | 2013 | Journal of Environmental Sciences2013，25，1： | 8 |
| 6 | Appraisal of the Quality and Contents of Clinical Practice Guidelines for Hypertension Management in Chinese Medicine: A Systematic Review显示文摘Objective: To evaluate the quality and consistency of recommendations in the clinical practice guidelines(CPGs) for hypertension in Chinese medicine(CM). Methods: CM CPGs were identified from 5 electronic databases and hand searches through related handbooks published from January 1990 to December 2013. Three reviewers independently appraised the CPGs based on the Appraisal of Guidelines for Research and Evaluation(AGREE Ⅱ) instrument, and compared the CPGs' recommendations on CM syndrome pattern classification and treatment. Results: Five CM CPGs for hypertension were included. The quality score of the evidence-based(EB) guideline was higher than those of the consensus-based with no explicit consideration of evidence-based(CB-EB) and the consensus-based(CB) guidelines. Three out of five patterns in the CPGs were recommended by the EB guideline. Tianma Gouteng Formula(天麻钩藤复方) in the EB guideline was recommended mostly for hypertension patients with pattern of ascendant hyperactivity of Gan(Liver)-yang and pattern of yin deficiency with yang hyperactivity in the CPGs. Acupuncture and massage were recommended for Grade Ⅰ and Grade Ⅱ hypertension with severe symptoms weakening the quality of life in the EB guideline. For Grade Ⅰ and Grade Ⅱ hypertension, CM could be used alone, while for Grade Ⅲ hypertension, they should be used in combination with Western medicines. Conclusion: The quality of EB guideline was higher than those of CB and CB-EB CPGs in CM for hypertension and CM should be prescribed alone or combined with Western medicines based on the grade of hypertension. | YUWEN Ya HAN Xue-jie WENG Wei-liang ZHAO Xue-yao LIU Yu-qi LI Wei-qiang LIU Da-sheng WANG Yan-ping LU Ai-ping | 2018 | Chinese Journal of Integrative Medicine2018，24，7： | 8 |
| 7 | Biofilm Microenvironment-Responsive Nanotheranostics for Dual-Mode Imaging and Hypoxia-Relief-Enhanced Photodynamic Therapy of Bacterial Infections显示文摘The formation of bacterial biofilms closely associates with infectious diseases.Until now,precise diagnosis and effective treatment of bacterial biofilm infections are still in great need.Herein,a novel multifunctional theranostic nanoplatform based on MnO_(2)nanosheets(MnO_(2)NSs)has been designed to achieve pH-responsive dual-mode imaging and hypoxia-relief-enhanced antimicrobial photodynamic therapy(aPDT)of bacterial biofilm infections.In this study,MnO_(2)NSs were modified with bovine serum albumin(BSA)and polyethylene glycol(PEG)and then loaded with chlorin e_(6)(Ce_(6))as photosensitizer to form MnO_(2)-BSA/PEG-Ce_(6)nanosheets(MBP-Ce_(6)NSs).After being delivered into the bacterial biofilm-infected tissues,the MBP-Ce_(6)NSs could be decomposed in acidic biofilm microenvironment and release Ce_(6)with Mn^(2+),which subsequently activate both fluorescence(FL)and magnetic resonance(MR)signals for effective dual-mode FL/MR imaging of bacterial biofilm infections.Meanwhile,MnO_(2)could catalyze the decomposing of H2O_(2)in biofilm-infected tissues into O_(2)and relieve the hypoxic condition of biofilm,which significantly enhances the efficacy of aPDT.An in vitro study showed that MBP-Ce_(6)NSs could significantly reduce the number of methicillin-resistant Staphylococcus aureus(MRSA)in biofilms after 635nm laser irradiation.Guided by FL/MR imaging,MRSA biofilm-infected mice can be efficiently treated by MBP-Ce_(6)NSs-based aPDT.Overall,MBP-Ce_(6)NSs not only possess biofilm microenvironment-responsive dual-mode FL/MR imaging ability but also have significantly enhanced aPDT efficacy by relieving the hypoxia habitat of biofilm,which provides a promising theranostic nanoplatform for bacterial biofilm infections. | Weijun Xiu Siyu Gan Qirui Wen Qiu Qiu Sulai Dai Heng Dong Qiang Li Lihui Yuwen Lixing Weng Zhaogang Teng Yongbin Mou Lianhui Wang | 2020 | Research2020，，1： | 7 |
| 8 | 0.75 Gbit/s high-speed classical key distribution with mode-shift keying chaos synchronization of Fabry–Perot lasers显示文摘High-speed physical key distribution is diligently pursued for secure communication.In this paper,we propose and experimentally demonstrate a scheme of high-speed key distribution using mode-shift keying chaos synchronization between two multi-longitudinal-mode Fabry–Perot lasers commonly driven by a super-luminescent diode.Legitimate users dynamically select one of the longitudinal modes according to private control codes to achieve mode-shift keying chaos synchronization.The two remote chaotic light waveforms are quantized to generate two raw random bit streams,and then those bits corresponding to chaos synchronization are sifted as shared keys by comparing the control codes.In this method,the transition time,i.e.,the chaos synchronization recovery time is determined by the rising time of the control codes rather than the laser transition response time,so the key distribution rate is improved greatly.Our experiment achieved a 0.75-Gbit/s key distribution rate with a bit error rate of 3.8×10^(−3)over 160-km fiber transmission with dispersion compensation.The entropy rate of the laser chaos is evaluated as 16 Gbit/s,which determines the ultimate final key rate together with the key generation ratio.It is therefore believed that the method pays a way for Gbit/s physical key distribution. | Hua Gao Anbang Wang Longsheng Wang Zhiwei Jia Yuanyuan Guo Zhensen Gao Lianshan Yan Yuwen Qin Yuncai Wang | 2021 | Light(Science & Applications)2021，10，9： | 7 |
| 9 | Boron modulating electronic structure of FeN4C to initiate high-efficiency oxygen reduction reaction and high-performance zinc-air battery显示文摘The biggest challenge is to develop a low cost and readily available catalyst to replace expensive commercial Pt/C for efficient electrochemical oxygen reduction reaction(ORR).In this research,closo-[B_(12)H_(12)]^(2−)and 1,10-phenanthroline-iron complexes were introduced into the porous metal-organic framework by impregnation method,and further annealing treatment achieved the successful anchoring of single-atom-Fe in B-doped CN Matrix(FeN4CB).The ORR activity of FeN4CB is comparable to the widely used commercial 20 wt%Pt/C.Where the half-wave potential(E_(1/2))in alkaline medium up to 0.84 V,and even in the face of challenging ORR in acidic medium,the E_(1/2)of ORR driven by FeN4CB is still as high as 0.81 V.When FeN4CB was used as air cathode,the open circuit voltage of Zn-air battery reaches 1.435 V,and the power density and specific capacity are as high as 177 mW cm^(−2)and 800 mAh g_(Zn)^(−1)(theoretical value:820 mAh g_(Zn)^(−1)),respectively.The dazzling point of FeN4CB also appears in the high ORR stability,whether in alkaline or acidic media,E_(1/2)and limiting current density are still close to the initial value after 5000 times cycles.After continuously running the charge-discharge test for 220 h,the charge voltage and discharge voltage of the rechargeable zinc-air battery with FeN4CB as the air cathode maintained the initial state.Density functional theory calculations reveals that introducing B atom to Fe–N4–C can adjust the electronic structure to easily break O=O bond and significantly reduce the energy barrier of the rate-determining step resulting in an improved ORR activity. | Xue Zhao Xue Li Zenghui Bi Yuwen Wang Haibo Zhang Xiaohai Zhou Quan Wang Yingtang Zhou Huaisheng Wang Guangzhi Hu | 2022 | Journal of Energy Chemistry2022，31，3： | 6 |
| 10 | Recent advances in detoxification strategies for zearalenone contamination in food and feed显示文摘Zearalenone(ZEN)is a widely distributed mycotoxin that frequently contaminates crops and animal feed.ZEN can cause serious health problems in livestock and humans alike,leading to great economic losses in the food industry and livestock farming.Therefore,approaches for efficient ZEN decontamination in food and feed are urgently needed.Traditional physical and chemical methods may decrease the nutritional quality of food and palatability of feed,or leading to residues and safety concerns.By contrast,biological methods for the removal or degradation of ZEN overcome these problems,especially for biological degradation by microorganisms and specific enzymes extracted from strains that can convert ZEN to less toxic or even completely harmless products.In this review,we comprehensively describe methods for ZEN degradation,focusing especially on biological strategies.Finally,emerging strategies and advice on remaining challenges in biodegradation research are also briefly discussed. | Na Wu Wen Ou Zhidong Zhang Yuwen Wang Qing Xu He Huang | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 5 |
| 11 | Effect of Seawater Soaking on Explosive Cornea Injury显示文摘Objective: To observe the changes in corneal tissue after explosive corneal injury and the effect of seawater soaking on the healing of cornea after explosive injury with the help ofoptical microscope. Methods: Make 10 similar explosive injury models of rabbit′s eyeball using 10 adult greyrabbits. For each rabbit, both eyes are artificially injured through explosion; its right eye is the comparison eye and after the injury the left eye is soaked in seawater for 30 minutes.Conduct slit lamp examinations, fluorescein dyeing, and ultrasonic cornea thickness metering on the corneas at intervals, that is, before the injury, 1 , 2, 3, 4, 5, 7, 9, 12, 15days after the injury respectively. Examine the corneas under the optical microscope andmake comparisons.Results: The corneal thickness of the experiment eye becomes apparently thicker than thatof the comparison eye after the injury. The corneal clouding of the former apparentlyaggravates compared with the latter. The healing of corneal epithelium in the injured eye isslower compared with that in the comparison eye. Comparative examination under the opticalmicroscope shows: after the injury, the corneal tissue of the experiment eye changesdistinctly, its healing is delayed and the vascularization degree becomes high in cornealstroma.Conclusion: Scars and vascularization of various degrees will appear in corneal stroma afterexplosive injuries. Seawater soaking will have bad effects on the healing of the corneainjured in explosions. | Suihua Chen, Zhenping Huang, Lili Wang, Yuwen Lu, Yi WangDepartment of Ophthalmology, General Hospital of Nanjing Military Command, PLA , Nanjing 210002, China | 2002 | Eye Science2002，18，1X： | 4 |
| 12 | A Dynamic Load Balancing Method of Cloud-Center Based on SDN显示文摘In order to achieve dynamic load balancing based on data fl ow level, in this paper, we apply SDN technology to the cloud data center, and propose a dynamic load balancing method of cloud center based on SDN. The approach of using the SDN technology in the current task scheduling flexibility, accomplish real-time monitoring of the service node flow and load condition by the Open Flow protocol. When the load of system is imbalanced, the controller can allocate globally network resources. What's more, by using dynamic correction, the load of the system is not obvious tilt in the long run. The results of simulation show that this approach can realize and ensure that the load will not tilt over a long period of time, and improve the system throughput. | WANG Yong TAO Xiaoling HE Qian KUANG Yuwen | 2016 | China Communications2016，13，2： | 4 |
| 13 | Design of two-stage membrane reactor for the conversion of coke-oven gas to H_2 and CO显示文摘The catalyst function was achieved in two regions in an oxygen permeation membrane reactor: H2 dissociated and reacted with lattice oxygen or oxygen ions to form H2 O near the membrane surface. The H2 O formed could react with the residual CH4 away from the membrane surface area. | Zhibin Yang Yuwen Zhang Xueguang Wang Weizhong Ding | 2014 | Journal of Energy Chemistry2014，23，4： | 4 |
| 14 | Influence of MoSi_(2) on oxidation protective ability of TaB_(2)-SiC coating in oxygen-containing environments within a broad temperature range显示文摘TaB_(2)-SiC coating modified by different content of MoSi_(2) was fabricated on graphite substrate with SiC inner coating by liquid phase sintering to elevate the anti-oxidation capability of the TaB_(2)-SiC coatings.As compared to the sample with the TaB_(2)-40wt% SiC coating,the coating sample modified with MoSi_(2) exhibited a weight gain trend at lower temperatures,the fastest weight loss rate went down by 76%,and the relative oxygen permeability value reduced from about 1% to near 0.More importantly,the large amount of SiO_(2) glass phase produced over the coating during oxidation was in contact with the modification of MoSi_(2),which was proved to be beneficial to the dispersion of Ta-oxides.A concomitantly formed continuous Ta-Si-O-B compound glass layer showed excellent capacity to prevent oxygen penetration.However,when the TaB_(2) content was sacrificed to increase the MoSi_(2) content,the relative oxygen permeability of the coating increased instead of decreased.Thus,on the basis of ample TaB_(2) content,increasing the MoSi_(2) content of the coating is conducive to reducing the relative oxygen permeability of the coatings in a broad temperature region. | Xuanru REN Junshuai LV Wei LI Yuwen HU Ke SUN Can MA Hong’ao CHU Weiguang WANG Leihua XU Ziyu LI Peizhong FENG | 2020 | Journal of Advanced Ceramics2020，9，6： | 4 |
| 15 | NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc显示文摘Background:Cisplatin-based chemotherapy with concurrent radiotherapy is a standard treatment for advanced esophageal squamous cell carcinoma(ESCC).NS1-binding protein(NS1-BP),a member of the BTB-kelch protein fam-ily,has been shown to inhibit the proliferation of Hela cells by suppressing c-Myc.In the present study,we examined the potential function role of NS1-BP expression in ESCC,and particularly,the sensitivity of ESCC to radiotherapy.Methods:NS1-BP expression was examined using immunohistochemistry in two cohorts(n=98 for the training cohort;n=46 for independent validation cohort)of ESCC patients receiving cisplatin-based chemotherapy and con-current radiotherapy.Normal esophageal mucosal tissue blocks were used as a control.We also conducted a series of in vitro and in vivo experiments to examine the potential effects of over-expressing NS1-BP on ESCC cells,and particu-larly their sensitivity to ionizing irradiation.Results:In the training cohort,NS1-BP downregulation was observed in 59%(85/144)of the ESCC specimens.NS1-BP downregulation was associated with chemoradiotherapeutic resistance and shorter disease-specific survival(DSS)in both the training and validation cohorts.Over-expressing NS1-BP in cultured ESCC cells substantially increased the cellular response to irradiation both in vitro and in vivo.NS1-BP also significantly enhanced IR-induced apoptosis,and abrogated IR-induced G2/M cell-cycle arrest and ATM/Chk1 phosphorylation.Immunoprecipitation assays indicated that NS1-BP could interact with c-Myc promoter regions to inhibit its transcription.In ESCC tissues,c-Myc expression was inversely correlated with NS1-BP levels,and was associated with a shorter DSS.Conclusions:Our findings highlight the role and importance of NS1-BP in radiosensitivity of ESCC.Targeting the NS1-BP/c-Myc pathway may provide a novel therapeutic strategy for ESCC. | Yuwen Wang Jingjing Cheng Dan Xie Xiaofeng Ding Hailing Hou Xi Chen Puchun Er Furong Zhang Lujun Zhao Zhiyong Yuan Qingsong Pang Ping Wang Dong Qian | 2018 | Cancer Communications2018，38，1： | 4 |
| 16 | Establishment of a dmp based maternal haploid induction system for polyploid Brassica napus and Nicotiana tabacum显示文摘Doubled haploid(DH) technology is used to obtain homozygous lines in a single generation, a technique that significantly accelerates the crop breeding trajectory. Traditionally, in vitro culture is used to generate DHs, but this technique is limited by species and genotype recalcitrance. In vivo haploid induction(HI) through seed is widely and efficiently used in maize and was recently extended to several other crops. Here we show that in vivo HI can be triggered by mutation of DMP maternal haploid inducer genes in allopolyploid(allotetraploid) Brassica napus and Nicotiana tabacum. We developed a pipeline for selection of DMP orthologs for clustered regularly interspaced palindromic repeats mutagenesis and demonstrated average amphihaploid induction rates of2.4% and 1.2% in multiple B. napus and N. tabacum genotypes, respectively. These results further confirmed the HI ability of DMP gene in polyploid dicot crops. The DMP-HI system offers a novel DH technology to facilitate breeding in these crops. The success of this approach and the conservation of DMP genes in dicots suggest the broad applicability of this technique in other dicot crops. | Yu Zhong Yuwen Wang Baojian Chen Jinchu Liu Dong Wang Mengran Li Xiaolong Qi Chenxu Liu Kim Boutilier Shaojiang Chen | 2022 | Journal of Integrative Plant Biology2022，64，6： | 4 |
| 17 | Six sigma robust design optimization for thermal protection system of hypersonic vehicles based on successive response surface method显示文摘Lightweight design is important for the Thermal Protection System(TPS) of hypersonic vehicles in that it protects the inner structure from severe heating environment. However, due to the existence of uncertainties in material properties and geometry, it is imperative to incorporate uncertainty analysis into the design optimization to obtain reliable results. In this paper, a six sigma robust design optimization based on Successive Response Surface Method(SRSM) is established for the TPS to improve the reliability and robustness with considering the uncertainties. The uncertain parameters related to material properties and thicknesses of insulation layers are considered and characterized by random variables following normal distributions. By employing SRSM, the values of objective function and constraints are approximated by the response surfaces to reduce computational cost. The optimization is an iterative process with response surfaces updating to find the true optimal solution. The optimization of the nose cone of hypersonic vehicle cabin is provided as an example to illustrate the feasibility and effectiveness of the proposed method. | Jingjing ZHU Xiaojun WANG Haiguo ZHANG Yuwen LI Ruixing WANG Zhiping QIU | 2019 | Chinese Journal of Aeronautics2019，32，9： | 4 |
| 18 | Design and application of an Electric Tail Rotor Drive Control(ETRDC) for helicopters with performance tests显示文摘With the development of electric helicopters' motor technology and the widespread use of electric drive rotors, more aircraft use electric rotors to provide thrust and directional control.For a helicopter tail rotor, the wake of the main rotor influences the tail rotor's inflow and wake.In the procedure of controlling, crosswind will also cause changes to the tail disk load. This paper describes requirements and design principles of an electric motor drive and variable pitch tail rotor system. A particular spoke-type architecture of the motor is designed, and the performance of blades is analyzed by the CFD method. The demand for simplicity of moving parts and strict constraints on the weight of a helicopter makes the design of electrical and mechanical components challenging. Different solutions have been investigated to propose an effective alternative to the mechanical actuation system. A test platform is constructed which can collect the dynamic response of the thrust control. The enhancement of the response speed due to an individual motor speed control and variable-pitch system is validated. | Yuwen ZHANG Chen JIANG Yunjie WANG Fan SUN Haowen WANG | 2018 | Chinese Journal of Aeronautics2018，31，9： | 3 |
| 19 | Recent Developments of Modulation and Control for High-Power Current-Source-Converters Fed Electric Machine Systems显示文摘The pulse-width-modulated(PWM)current-source converters(CSCs)fed electric machine systems can be considered as a type of high reliability energy conversion systems,since they work with the long-life DC-link inductor and offer high fault-tolerant capability for short-circuit faults.Besides,they provide motor friendly waveforms and four-quadrant operation ability.Therefore,they are suitable for high-power applications of fans,pumps,compressors and wind power generation.The purpose of this paper is to comprehensively review recent developments of key technologies on modulation and control of high-power(HP)PWM-CSC fed electric machines systems,including reduction of low-order current harmonics,suppression of inductor–capacitor(LC)resonance,mitigation of common-mode voltage(CMV)and control of modular PWM-CSC fed systems.In particular,recent work on the overlapping effects during commutation,LC resonance suppression under fault-tolerant operation and collaboration of modular PMW-CSCs are described.Both theoretical analysis and some results in simulations and experiments are presented.Finally,a brief discussion regarding the future trend of the HP CSC fed electric machines systems is presented. | Pengcheng Liu Zheng Wang Sanmin Wei Yuwen Bo Shaoning Pu | 2020 | CES Transactions on Electrical Machines and Systems2020，4，3： | 3 |
| 20 | Computational thermodynamics, computational kinetics, and materials design显示文摘Computational thermodynamics,known as CALPHAD method when dawned in 1950s,aimed at coupling phase diagrams with thermochemistry by computational techniques.It eventually evolves toward kinetic simulations integrated with thermodynamic calculations,i.e.,computational kinetics,including diffusion-controlled phase transformation,precipitation simulation,and phasefield simulation.In the meantime,thermodynamic,mobility,and physical property databases for multi-component and multi-phase materials,served as basic knowledge for materials design,are critically evaluated by CALPHAD approach combining key experiments,first-principles calculations,statistic methods,and empirical theories.The combination of these computational techniques with their conjugated databases makes it possible to simulate phase transformations and predict the microstructure evolution in real materials in a foreseeable future.Further links to microand macro-scale simulations lead to a multi-scale computational framework,and aid the search for the quantitativerelations among chemistry,process,microstructures,and materials properties in order to accelerate materials development and deployment.This is a new route of materials and process design pursued by Integrated Computational Materials Engineering(ICME)and Materials Genome Initiative(MGI).This article presents a review on the basic theories and applications,the state of the art and perspective of computational thermodynamics and kinetics. | Xiao-Gang Lu Zhuo Wang Yuwen Cui Zhanpeng Jin | 2014 | Chinese Science Bulletin2014，59，15： | 3 |
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