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| 1 | Dual function of Arabidopsis A TAF1 in abiotic and biotic stress responses显示文摘NAC 家庭基因编码涉及多样的生物过程的植物特定的抄写因素。在这研究, Arabidopsis NAC 基因 ATAF1 被发现被干旱导致,高咸度, abscisic 酸(骆驼毛的织物) ,甲基 jasmonate,机械伤害,并且 Botrytis cinerea 感染。ATAF1 的重要正式就职在受到干旱或高咸度的骆驼毛的织物缺乏的变异的 aba2 被发现,揭示表示的骆驼毛的织物无关的机制。Arabidopsis ATAF1-overexpression 线显示了许多改变的显型,包括侏儒症和短主要的根。而且,在 vivo,实验显示 ATAF1 是真正的管理者 modulating 植物对许多不能生活的压力和 necrotrophic 病原体感染的回答。在 Arabidopsis 的 ATAF1 的 Overexpression 增加了植物敏感到骆驼毛的织物,盐,和氧化压力。特别, ATAF1 overexpression 种,然而并非异种排队显示出的显著地提高的植物忍耐到干旱。另外, ATAF1 overexpression 提高了植物危险性到 necrotrophic 病原体 B。cinerea,但是没改变 P 的无毒害或剧毒的紧张引起的疾病症状。syringae pv 西红柿 DC3000。转基因的植物 overexpressing ATAF1 对氧化应力过分敏感,建议反应的氧中介可能与响应病原体和不能生活的压力的调停 ATAF1 的发信号有关。 | Yaorong Wu Zhiyong Deng Jianbin Lai Yiyue Zhang Cuiping Yang Bojiao Yin Qingzhen Zhao Ling Zhang Yin Li Chengwei Yang Qi Xie | 2009 | Cell Research2009，19，11： | 56 |
| 2 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 3 | Characteristics of dry friction backward whirl—A self-excited oscillation in rotor-to-stator contact systems显示文摘In this paper,the response characteristics of dry friction backward whirl of a general rotor/stator model,which accounts for both the dynamics of the rotor and the stator as well as the friction and the deformation at the contact surfaces,are investigated.The existence boundaries and the whirl frequencies of the dry friction backward whirl are determined analytically.It is found that there are two or three existence boundaries of the dry friction backward whirl that usually form two existence regions,either standing completely separately,or overlapping each other partly,or one containing the other completely,depending upon the system parameters.The whirl frequencies in the two existence regions are quite different and may jump between the lower and the higher values with the variation of the rotating speed.The results have been found to have good correspondence in the related rotor/stator rubbing experiments. | JIANG Jun,SHANG ZhiYong & HONG Ling MOE Key Laboratory of Strength and Vibration,Xi’an Jiaotong University,Xi’an 710049,China | 2010 | Science China(Technological Sciences)2010，53，3： | 8 |
| 4 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 5 | Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a global pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2).SARS-Co V-2 infection was first detected in Wuhan,China in late December 2019.The virus was spreading rapidly to other cities of China and accumulating cases had been reported(Li et al.2020). | Xiaoping Chen Qunqun Jiang Zhiyong Ma Jiaxin Ling Wenjia Hu Qian Cao Pingzheng Mo Lei Yao Rongrong Yang Shicheng Gao Xien Gui Wei Hou Yong Xiong Jinlin Li Yongxi Zhang | 2020 | Virologica Sinica2020，35，6： | 6 |
| 6 | Near-surface wind environment in the Yarlung Zangbo River basin,southern Tibetan Plateau显示文摘Aeolian processes have been studied extensively at low elevations,but have been relatively little studied at high elevations.Aeolian sediments are widely distributed in the Yarlung Zangbo River basin,southern Tibetan Plateau,which is characterized by low pressure and low temperature.Here,we comprehensively analyzed the wind regime using data since 1980 from 11 meteorological stations in the study area,and examined the interaction between the near-surface wind and aeolian environment.The wind environment exhibited significant spatial and temporal variation,and mean wind speed has generally decreased on both annual and seasonal bases since 1980,at an average of 0.181 m/(s•10a).This decrease resulted from the reduced contribution of maximum wind speed,and depended strongly on variations of the frequency of sand-driving winds.The drift potential and related parameters also showed obvious spatial and temporal variation,with similar driving forces for the wind environment.The strength of the wind regime affected the formation and development of the aeolian geomorphological pattern,but with variation caused by local topography and sediment sources.The drift potential and resultant drift direction were two key parameters,as they quantify the dynamic conditions and depositional orientation of the aeolian sediments.Wind affected the spatial variation in sediment grain size,but the source material and complex topographic effects on the near-surface wind were the underlying causes for the grain size distribution of aeolian sands.These results will support efforts to control aeolian desertification in the basin and improve our understanding of aeolian processes in high-elevation environments. | YANG Junhuai XIA Dunsheng WANG Shuyuan TIAN Weidong MA Xingyue CHEN Zixuan GAO Fuyuan LING Zhiyong DONG Zhibao | 2020 | Journal of Arid Land2020，12，6： | 5 |
| 7 | Coastal environment of the past millennium recorded by a coastal dune in Fujian,China显示文摘Coastal dune is a common aeolian geomorphology in a sandy coast,which records the evolution process of the aeolian landscape system and reflects the complex interaction among land surface,atmosphere and ocean.Coast is a sensitive area to global climate change.Restricted by chronology,most previous researches in China focused only on the cause of formation of coastal dunes.In recent years,the development of optically stimulated luminescence (OSL) dating provides a good method and acts as a carrier for coastal dunes to paleoclimate and paleoenvironmental studies.In this study,we selected an aeolian dune at the Anshan archaeological site,Fujian,China as the research object based on field observations.For determining their sedimentary stages and the primary influencing factors,we used the OSL dating method to construct a chronological framework for the aeolian dune.In addition,the sizes of grains were analyzed for identifying factors influencing the winter monsoon during the Medieval Warm Period (MWP) and the Little Ice Age (LIA) in this area.The results showed that the deposition of the aeolian dune was closely related to variations in the winter monsoon intensity.The changes of the winter monsoon were similar to the tendency of the East Asian winter monsoon,although there were several sub-fluctuations.From an overall perspective,the winter monsoon was strengthened during the MWP (1050–1300) .The results of a power spectrum analysis showed that the intensity of the East Asian winter monsoon is correlated with sunspot activity. | JIN Jianhui LI Zhizhong JIANG Feng deng tao HU Fan'gen LING Zhiyong | 2016 | Journal of Arid Land2016，8，5： | 3 |
| 8 | Expression, purification of a synthetic fuse-protein-TSF from PF4 and TSP1 fragments and its effect on angio-genesis and tumor growth显示文摘Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF | SHEN Xianrong JI Dongmei HU Youqing JIA Fuxing DENG Xinxian WANG Ling CHU Zhiyong JIANG Dingwen LEI Chengxiang HUANG Jiansheng HU Xinran REN Darning | 2001 | Chinese Science Bulletin2001，46，24： | 2 |
| 9 | PTEN’s regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia显示文摘 | Cheng Zhiyong Liang Wentong Yang Xiaoyang Pan Ling | 2012 | Medical Oncology2012，，2： | 2 |
| 10 | Genetic architecture of maize yield traits dissected by QTL mapping and GWAS in maize显示文摘The study of yield traits can reveal the genetic architecture of grain yield for improving maize production.In this study, an association panel comprising 362 inbred lines and a recombinant inbred line population derived from X178 × 9782 were used to identify candidate genes for nine yield traits. High-priority overlap(HPO) genes, which are genes prioritized in a genome-wide association study(GWAS), were investigated using coexpression networks. The GWAS identified 51 environmentally stable SNPs in two environments and 36 pleiotropic SNPs, including three SNPs with both attributes. Seven hotspots containing 41 trait-associated SNPs were identified on six chromosomes by permutation. Pyramiding of superior alleles showed a highly positive effect on all traits, and the phenotypic values of ear diameter and ear weight consistently corresponded with the number of superior alleles in tropical and temperate germplasm. A total of 61 HPO genes were detected after trait-associated SNPs were combined with the coexpression networks. Linkage mapping identified 16 environmentally stable and 16 pleiotropic QTL.Seven SNPs that were located in QTL intervals were assigned as consensus SNPs for the yield traits.Among the candidate genes predicted by our study, some genes were confirmed to function in seed development. The gene Zm00001 d016656 encoding a serine/threonine protein kinase was associated with five different traits across multiple environments. Some genes were uniquely expressed in specific tissues and at certain stages of seed development. These findings will provide genetic information and resources for molecular breeding of maize grain yield. | Xiao Zhang Zhiyong Ren Bowen Luo Haixu Zhong Peng Ma Hongkai Zhang Hongmei Hu Yikai Wang Haiying Zhang Dan Liu Ling Wu Zhi Nie Yonghui Zhu Wenzhu He Suzhi Zhang Shunzong Su Yaou Shen Shibin Gao | 2022 | The Crop Journal2022，10，2： | 2 |
| 11 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 12 | Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos显示文摘The Dux gene plays an important role in mouse embryo development(De Iaco et al.,2017;Hendrickson et al.,2017;Whiddon et al.,2017).It participates in the maternal-to-zygotic transition(MTZ),which mainly includes maternal transcript degradation and zygotic genome activation(ZGA)and is the key process for embryonic development.Approximately 11-100 copies of the DUX4 gene form a tandem cluster in the human genome(Snider et al.,2009,2010). | Yubing Liu Xinmei Lu Min Ye Ling Wang Rongxin Tang Zhiyong Yang Bongkoch Turathum Chenchen Liu Yujing Xue Menghua Wu Yannan Yang Ermeng Gao Di Zhang Feng Yang Keh-Kooi Kee Xingxu Huang Guanglei Li Ri-Cheng Chian | 2022 | Journal of Genetics and Genomics2022，49，10： | 1 |
| 13 | Oral administration of dibutyryl adenosine cyclophosphate improved growth performance in weaning piglets by enhancing lipid fatty acids metabolism显示文摘Dibutyryl adenosine cyclophosphate(dbc AMP-Ca), an analog of cyclic adenosine monophosphate(c AMP), plays greater roles in regulating physiological activities and energy metabolism than c AMP. The aim of this study was to investigate the effect of oral administration of dbc AMP-Ca on growth performance and fatty acids metabolism in weaning piglets. A total of 14 early weaning piglets(7 ± 1 d of age,3.31 ± 0.09 kg, Landrace ? Large White ? Duroc) were randomly divided into 2 groups: control group and dbc AMP-Ca group, and the piglets received 7 m L of 0.9% Na Cl or 1.5 mg dbc AMP-Ca dissolved in 7 m L of 0.9% Na Cl per day for 10 d, respectively. The results showed that the average daily gain(ADG)increased by 109.17%(P < 0.05) in the dbc AMP-Ca group compared with the control group. Besides,dbc AMP-Ca significantly decreased blood high density lipoprotein cholesterol(HDLC) concentration(P < 0.05) and significantly increased blood low density lipoprotein cholesterol(LDLC) concentration(P < 0.05) compared with the control group. Further, liver C18:2 n6 t content significantly increased in dbc AMP-Ca group(P < 0.05) compared with the control group. With the increase of C18:2 n6 t content,the m RNA expression levels of peroxisome proliferator-activated receptor a(PPARa) and hormone sensitive glycerol three lipase(HSL), of which genes are related to lipid metabolism, were also significantly increased(P < 0.05 or P < 0.01). All of the results indicated that dbc AMP-Ca improved the ADG, which was probably done by regulating fatty acids metabolism in the liver of weaning piglets. | Guanya Li Ling Chang Guanglei Zhang Zehe Song Dan Wan Chunyan Xie Hong Wang Zhiyong Fan | 2018 | Animal Nutrition2018，，3： | 1 |
| 14 | Baicalein protects Human melanocytes from H 2 O 2 -induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway显示文摘 | Bangmin Liu Zhe Jian Qiang Li Kai Li Zhiyong Wang Ling Liu Lingzhen Tang Xiuli Yi Hua Wang Chunying Li Tianwen Gao | 2012 | Free Radical Biology and Medicine2012，，2： | 1 |
| 15 | Transcriptional and Post-transcriptional Modulation of SQU and KEW Activities in the Control of Dorsal-Ventral Asymmetric Flower Development in Lotus japonicus显示文摘在 Papilionoideae 荚,莲花 japonicus,发展背面腹(DV ) 不对称的花被二 TB1/CYCLOIDEA/PCF (TCP ) 基因,摆平的标准(SQU ) 和翻身翅膀主要在莲花(英国伦敦郊外的村名) 控制,它分别地决定背面、侧面的身份。然而,这二高度相应的基因怎么安排他们的多样的功能的分子的基础仍然保持不清楚。这里,我们分析了他们的表示层次,并且调查了 SQU 和英国伦敦郊外的村名的 transcriptional 活动。我们证明 SQU 拥有激活和压抑活动,当英国伦敦郊外的村名仅仅充当使活跃之物时。他们形成人 -- 并且 heterodimers,然后联合地在抄写水平调整他们的表示。而且,我们识别了 post-transcriptional 修正, phosphorylation 和 ATP/GTP 绑定的二种类型,哪个能影响他们的 transcriptional 活动。在 SQU 和英国伦敦郊外的村名的 ATP/GTP 有约束力的主题的变化导致忍受变异的蛋白质显示器有缺陷者 DV 不对称的花开发的 phosphorylation,和转基因的植物的失败,显示二结合修正为他们的多样的函数是必要的。总的来说, SQU 和英国伦敦郊外的村名活动精确在抄写和抄写以后的层次被调制,它可能连接 DV 不对称的花开发到不同生理的地位或发信号的小径。 | Zhiyong xu Kai Cheng Xin Li Jun Yang Shilei Xu Xiangling Cao Xiaohe Hu Wei Xie Ling Yuan Mike Ambrose Genyun Chen Hualing Mi Da Luo | 2016 | Molecular Plant2016，9，5： | 1 |
| 16 | PTEN’s regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia显示文摘 | Cheng Zhiyong Liang Wentong Yang Xiaoyang Pan Ling | 2012 | Medical Oncology2012，，2： | 1 |
| 17 | Baicalein protects Human melanocytes from H 2 O 2 -induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway显示文摘 | Bangmin Liu Zhe Jian Qiang Li Kai Li Zhiyong Wang Ling Liu Lingzhen Tang Xiuli Yi Hua Wang Chunying Li Tianwen Gao | 2012 | Free Radical Biology and Medicine2012，，2： | 1 |
| 18 | Decomposing or subliming? An investigation of thermal behavior of l -leucine显示文摘 | Jie Li Zhiyong Wang Xi Yang Ling Hu Yuwen Liu Cunxin Wang | 2006 | Thermochimica Acta2006，，2： | 1 |
| 19 | Evaluate the pyrolysis pathway of glycine and glycylglycine by TG–FTIR显示文摘 | Jie Li Zhiyong Wang Xi Yang Ling Hu Yuwen Liu Cunxin Wang | 2007 | Journal of Analytical and Applied Pyrolysis2007，，： | 1 |
| 20 | Can Immune Cell Function Assay Identify Patients at Risk of Infection or Rejection? A Meta-Analysis显示文摘 | Xiaoting Ling Jun Xiong Wenhua Liang Paul M. Schroder Linwei Wu Weiqiang Ju Yuan Kong Yushu Shang Zhiyong Guo Xiaoshun He | 2012 | Transplantation2012，，7： | 1 |
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