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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018,61,6: | 39 |
| 2 | Near-infrared responsive 5-fluorouracil and indocyanine green loaded MPEG-PCL nanoparticle integrated with dissolvable microneedle for skin cancer therapy显示文摘The prevalence of skin cancer is rising along with the rapid population aging in recent years.Traditional therapies,such as surgical treatment,radiotherapy,chemotherapy,photodynamic therapy,and immunotherapy,may accompany serious side effects,limiting their clinical benefits.According to the biological characteristics of skin cancer,we have already established two kinds of synergetic systems of photothermal therapy(microneedle)and chemotherapy,containing gold nanorods(GNR).Although the microneedle system exhibited great potential for skin cancer treatment,the system could be still improved further.So,we designed a near-infrared lightresponsive 5-fluorouracil(5-Fu)and indocyanine green(ICG)loaded monomethoxy-poly(ethylene glycol)-polycaprolactone(MPEG-PCL)nanoparticle(5-Fu-ICG-MPEG-PCL),and then 5-Fu-ICG-MPEG-PCL was integrated with a hyaluronic acid dissolvable microneedle system(HA MN)to get 5-Fu-ICG-MPEG-PCL loaded HA MN for treating skin cancers,including human epidermoid cancer and melanoma.In this system,hyaluronic acid,the microneedle carrier,possesses good skin penetration ability and is approved by FDA as a pharmaceutical adjuvant;5-Fu is recommended by FDA for skin cancer treatment;ICG,a photothermal agent,possesses a strong photothermal ability and is approved by FDA for its use in the human body.We hypothesized that 5-Fu-ICG-MPEG-PCL could be delivered by the dissolvable microneedle through the skin,and the release behavior of the drug in the nanoparticle could be controlled by near-infrared light for achieving a single-dose cure of skin cancer,improving the cure rate of skin cancer and providing a new idea and possibility for the clinical treatment of skin cancer. | Ying Hao YuWen Chen XinLong He Fan Yang RuXia Han ChengLi Yang Wei Li ZhiYong Qian | 2020 | Bioactive Materials2020,5,3: | 17 |
| 3 | Magnolol additive as a replacer of antibiotic enhances the growth performance of Linwu ducks显示文摘Magnolol rich in Magnolia officinalis is a bioactive polyphenolic compound. The aim of this study was to examine the effects of magnolol additive(MA) on growth performance, expression levels of antioxidantrelated genes, and intestinal mucosal morphology of Linwu ducks aged from 49 to 70 days, comparing with that of an antibiotic additive(colistin sulfate [CS]). A total of 275,49-day-old ducks were assigned to5 groups with 5 cages of 11 ducks each and fed diets supplemented with 0,100, 200 and 300 mg of MA/kg and 300 mg of CS/kg for 3 weeks, respectively. The results showed that the average daily body weight gain(ADG) was increased significantly in MA-fed groups(200 and 300 mg/kg), compared with the basal diet(BD) group(P < 0.05). The mRNA levels of superoxide dismutase-1(SOD1), manganese superoxide dismutase-2(MnSOD2) and catalase(CAT) were also increased significantly in MA groups(P < 0.05). In addition, hematoxylin and eosin staining revealed that Linwu ducks fed the diets with MA had more intact intestinal mucosa than those fed the BD and CS diets. In addition, ileal villus height, ileal villus height/crypt depth ratio(V/C) and duodenal V/C were also improved significantly(P < 0.05). Taken together, these data demonstrated that MA is an effective feed additive to enhance the growth performance of the Linwu ducks by improving the antioxidant and intestinal mucosal status, suggesting that MA will be a potential additive to replace antibiotic(CS). | Qian Lin Jianfei Zhao Kun Xie Yushi Wang Guili Hu Guitao Jiang Qiuzhong Dai Zhiyong Fan Jianhua He Xi He De-Xing Hou | 2017 | Animal Nutrition2017,,2: | 14 |
| 4 | Dietary L-theanine alleviated lipopolysaccharide-induced immunological stress in yellow-feathered broilers显示文摘L-theanine, a natural nonprotein amino acid with a high biological activity, is reported to exert anti-stress properties. An experiment with a 3 ? 2 factorial arrangement was conducted to investigate the effects of dietary L-theanine on growth performance and immune function in lipopolysaccharide(LPS)-challenged broilers. A total of 432 one-day-old male yellow-feathered broilers were randomly assigned to 3 dietary treatments(control, antibiotic and L-theanine diets) with 2 subgroups of each(6 replicate cages;12 birds/cage). Birds from each subgroup of the 3 dietary treatments were intra-abdominally injected with the same amount of LPS or saline at 24, 25, 26 d of age. Both dietary L-theanine and antibiotic improved(P < 0.05) the growth performance of birds before LPS injection(d 1 to 21). The effect of dietary L-theanine was better(P < 0.05) than that of antibiotic. Lipopolysaccharide decreased feed intake(FI) and body weight gain(BWG) from d 22 to 28(P < 0.05), BWG and feed to gain ratio(F:G) from d 29 to 56(P < 0.05), increased mortality in different growth periods(P < 0.05), elevated the levels of serum cortisol, a1-acid glycoprotein(a1-AGP), interleukin-6(IL-6) on d 24 and 25(P < 0.05), reduced immune organ indexes and contents of jejunal mucosal secretory immunoglobulin A(s Ig A) on d 28(P < 0.05). The decreased FI and BWG, as well as increased F:G and mortality in LPS-challenged birds, were alleviated by dietary L-theanine or antibiotic from d 29 to 56 and from d 1 to 56. Dietary L-theanine mitigated the elevated serum a1-AGP level on d 25, serum IL-6 concentration on d 24 and 26, and the decreased jejunal mucosal s Ig A content on d 28 of the LPS-challenged birds. The results indicated that L-theanine had potential to alleviate LPS-induced immune stress in broilers. | Rui Li Zehe Song Jianfei Zhao Dongxiao Huo Zhiyong Fan De-Xing Hou Xi He | 2018 | Animal Nutrition2018,,3: | 13 |
| 5 | Long-term trends of fine particulate matter and chemical composition in the Pearl River Delta Economic Zone (PRDEZ), China显示文摘在下午 2.5 层次理解趋势为提出是必要的干净空气计划。这份报纸在珀尔河三角洲经济地区(PRDEZ ) 为 2000 年从各种各样的出版来源分析下午 2.5 数据到 2010。在下午 2.5 团集中的长期的变化被分析。结果给那位首相看 2.5, 器官的碳(OC ) ,元素的碳(EC ) ,并且那么 42 显示出一个类似的趋势,在 2005 前增加然后稍微减少。年度普通下午 2.5 集中从 49.1 g ? | Xuemei WANG Weihua CHEN Duohong CHEN Zhiyong WU Qi Fan | 2016 | Frontiers of Environmental Science & Engineering2016,10,1: | 11 |
| 6 | Prognostic Significance of Tumor-infiltrating CD8^+ or CD3^+ T Lymphocytes and Interleukin-2 Expression in Radically Resected Non-small Cell Lung Cancer显示文摘 | Chuntao Tian Shixin Lu Qingxia Fan Weijie Zhang Shunchang Jiao Xiao Zhao Zhiyong Wu Liang Sun Liuxing Wang | 2015 | Chinese Medical Journal2015,,1: | 11 |
| 7 | SHP2 promotes proliferation of breast cancer cells through regulating Cyclin D1 stabilityviathe PI3K/AKT/GSK3β signaling pathway显示文摘Objective:The tyrosine phosphatase SHP2 has a dual role in cancer initiation and progression in a tissue type-dependent manner.Several studies have linked SHP2 to the aggressive behavior of breast cancer cells and poorer outcomes in people with cancer.Nevertheless,the mechanistic details of how SHP2 promotes breast cancer progression remain largely undefined.Methods:The relationship between SHP2 expression and the prognosis of patients with breast cancer was investigated by using the TCGA and GEO databases.The expression of SHP2 in breast cancer tissues was analyzed by immunohistochemistry.CRISPR/Cas9 technology was used to generate SHP2-knockout breast cancer cells.Cell-counting kit-8,colony formation,cell cycle,and EdU incorporation assays,as well as a tumor xenograft model were used to examine the function of SHP2 in breast cancer proliferation.Quantitative RT-PCR,western blotting,immunofluorescence staining,and ubiquitination assays were used to explore the molecular mechanism through which SHP2 regulates breast cancer proliferation.Results:High SHP2 expression is correlated with poor prognosis in patients with breast cancer.SHP2 is required for the proliferation of breast cancer cellsin vitro and tumor growthin vivo through regulation of Cyclin D1 abundance,thereby accelerating cell cycle progression.Notably,SHP2 modulates the ubiquitin–proteasome-dependent degradation of Cyclin D1viathe PI3K/AKT/GSK3βsignaling pathway.SHP2 knockout attenuates the activation of PI3K/AKT signaling and causes the dephosphorylation and resultant activation of GSK3β.GSK3βthen mediates phosphorylation of Cyclin D1 at threonine 286,thereby promoting the translocation of Cyclin D1 from the nucleus to the cytoplasm and facilitating Cyclin D1 degradation through the ubiquitin–proteasome system.Conclusions:Our study uncovered the mechanism through which SHP2 regulates breast cancer proliferation.SHP2 may therefore potentially serve as a therapeutic target for breast cancer. | Yue Yuan Yanling Fan Zicong Gao Xuan Sun He Zhang Zhiyong Wang Yanfen Cui Weijie Song Zhaosong Wang Fei Zhang Ruifang Niu | 2020 | Cancer Biology & Medicine2020,17,3: | 11 |
| 8 | Microstructural evolution and FCC twinning behavior during hot deformation of high temperature titanium alloy Ti65显示文摘Although the development of titanium alloys with working temperatures above 600?C faces enormous difficulties and challenges,the related research has not stopped.In the present work,detailed analyses on microstructure evolution and hot deformation behavior of a new temperature resistant 650?C titanium alloy Ti65 were investigated from micrometer scale to nanometer scale.The results revealed that lamellarαgrains gradually fragmentized and spheroidized during theα+βphase region compression and the orientation of the c-axis ofαgrains gradually aligned to radial directions,forming two high Schmid factors(SFs)value texture eventually with the increase of strain to 0.7.Moreover,there were some strengthening characters in theα+βphase region such as lenticularαsand nano silicide(TiZr)6 Si3.In theβphase region,fine equiaxed dynamic recrystallized(DRX)βgrains were formed.Besides,the variant selection ofαm′artensite followed Burgers orientation relationship during the compression process.The main deformation mechanisms of theα+βphase region were dislocation slip and orientation dependent spheroidization.Whereas,the deformation process in theβphase region was controlled byβgrain DRX.Interestingly,many nano scale FCC twins were generated at the interface ofαl′ath during deforming in theβphase region,which was firstly observed in Ti65 alloy. | Zhixin Zhang Jiangkun Fan Bin Tang Hongchao Kou Jian Wang Xin Wang Shiying Wang Qingjiang Wang Zhiyong Chen Jinshan Li | 2020 | Journal of Materials Science & Technology2020,47,14: | 10 |
| 9 | Dietary supplementation of Lonicera macranthoides leaf powder improves amino acid profiles in serum and longissimus thoracis muscle of growing-finishing pigs显示文摘A 60-days feeding trial was conducted to determine the effect of dietary supplementation of Lonicera macranthoides leaf(LML) on growth performance, meat quality, and free amino acid profiles in growingfinishing pigs. L. macranthoides leaves were harvested, air-dried and milled to powder. A total of 288 crossbred barrows(Large White x Landrace) with an average initial BW of 54.0 ± 3.4 kg were randomly allocated to 3 treatment groups and fed either a basal diet or a diet supplemented with 0.5% or 1.0% LML powder. Results showed that diet supplemented with LML powder did not affect average daily feed intake(ADFI) and feed: gain ratio(P> 0.05) in growing-finishing pigs. Moreover, diet supplemented with LML powder showed no significant effects on carcass traits(P > 0.05) including dressing percentage,backfat thickness and loin muscle area, and meat quality traits(P > 0.05) including meat color, intramuscular fat and cooking loss. However, diet supplemented with LML powder significantly improved free amino acid profiles in serum and longissimus thoracis muscle in growing-finishing pigs. Most importantly, dietary LML powder increased total free amino acids content(P < 0.001) and essential free amino acid content(P < 0.001) in longissimus thoracis muscle. These results indicate that LML has the potential to improve the nutritional value of meat through improving free amino acid profiles. | Cimin Long Xihong Zhou Qinhua Wang Chunyan Xie Fengna Li Zhiyong Fan Bin Zhang Zheng Ruan Xiao'an Chen Xin Wu Yulong Yin | 2016 | Animal Nutrition2016,,4: | 8 |
| 10 | An Energy Efficient Design for UAV Communication With Mobile Edge Computing显示文摘This paper considers a UAV communication system with mobile edge computing(MEC).We minimize the energy consumption of the whole system via jointly optimizing the UAV's trajectory and task assignment as well as CPU's computational speed under the set of resource constrains.To this end,we first derive the energy consumption model of data processing,and then obtain the energy consumption model of fixed-wing UAV's flight.The optimization problem is mathematically formulated.To address the problem,we first obtain the approximate optimization problem by applying the technique of discrete linear state-space approximation,and then transform the non-convex constraints into convex by using linearization.Furthermore,a concave-convex procedure(CCCP) based algorithm is proposed in order to solve the optimization problem approximately.Numerical results show the efficacy of the proposed algorithm. | Lingyan Fan Wu Yan Xihan Chen Zhiyong Chen Qingjiang Shi | 2019 | China Communications2019,16,1: | 8 |
| 11 | Orientation dependent behavior of tensile-creep deformation of hot rolled Ti65 titanium alloy sheet显示文摘The mill products like sheet always have one or more severe textures inevitably,and its effect on mechanical properties is not a negligible issue.The orientation dependent tensile-creep behavior induced by rolling texture of Ti65 titanium alloy sheet has been systematically investigated at 650℃.There are some anisotropic characteristics between TD and RD of Ti65 sheet.The UTS and TYS of TD are higher than RD at 650℃.Besides,the creep endurance time of TD(172.6–174.5 h)is about three times longer than RD(55.6–65.1 h)at 650℃and 240 MPa.Moreover,the grains are inclined to form Texture III■after creep along with TD,but to form Texture I■after creep along with RD.Finally,the crack initiation site is different during creep in TD and RD.The reason for anisotropic properties of tensile and creep has been summarized in two aspects:(i)the change of the SFs(Schmid factors)value between TD and RD;(ii)the difference of creep mechanism between TD(grain boundary sliding)and RD(dislocation slip).Anisotropy of Ti65 sheet should be fully considered to increase structural efficiency in the engineering design and application. | Zhixin Zhang Jiangkun Fan Ruifeng Li Hongchao Kou Zhiyong Chen Qingjiang Wang Hailong Zhang Jian Wang Qi Gao Jinshan Li | 2021 | Journal of Materials Science & Technology2021,,16: | 7 |
| 12 | Current progress in developing metal oxide nanoarrays-based photoanodes for photoelectrochemical water splitting显示文摘Solar energy driven photoelectrochemical(PEC) water splitting is a clean and powerful approach for renewable hydrogen production. The design and construction of metal oxide based nanoarray photoanodes is one of the promising strategies to make the continuous breakthroughs in solar to hydrogen conversion efficiency of PEC cells owing to their owned several advantages including enhanced reactive surface at the electrode/electrolyte interface, improved light absorption capability, increased charge separation efficiency and direct electron transport pathways. In this Review, we first introduce the structure,work principle and their relevant efficiency calculations of a PEC cell. We then give a summary of the state-of the-art research in the preparation strategies and growth mechanism for the metal oxide based nanoarrays, and some details about the performances of metal oxide based nanoarray photoanodes for PEC water splitting. Finally, we discuss key aspects which should be addressed in continued work on realizing high-efficiency metal oxide based nanoarray photoanodes for PEC solar water splitting systems. | Yongcai Qiu Zhenghui Pan Haining Chen Daiqi Ye Lin Guo Zhiyong Fan Shihe Yang | 2019 | Science Bulletin2019,64,18: | 7 |
| 13 | Effect of cathodic potential on stress corrosion cracking behavior of different heat-affected zone microstructures of E690 steel in artificial seawater显示文摘In this work,the stress corrosion cracking(SCC)behavior of E690 steel base metal(BM)and different heat-affected zone(HAZ)microstructures,i.e.,coarse grain HAZ(CGHAZ),fine grain HAZ(FGHAZ),and intercritical HAZ(ICHAZ),was investigated at different cathodic potentials in artificial seawater by slow strain rate tensile tests,scanning electron microscopy and electron back-scattered diffraction measurements.The results show that the HAZ microstructures and BM exhibit different SCC susceptibilities:FGHAZ | Yong Li Zhiyong Liu Endian Fan Yunhua Huang Yi Fan Bojie Zhao | 2021 | Journal of Materials Science & Technology2021,,5: | 6 |
| 14 | Live cell single molecule-guided Bayesian localization super resolution microscopy显示文摘 | Xu, Fan Zhang, Mingshu He, Wenting Han, Renmin Xue, Fudong Liu, Zhiyong Zhang, Fa Lippincott-Schwartz, Jennifer Xu, Pingyong | 2017 | Cell Research2017,27,5: | 6 |
| 15 | Photochemical indicators of ozone sensitivity: application in the Pearl River Delta, China显示文摘 | Lyumeng Ye Xuemei Wang Shaofeng Fan Weihua Chen Ming Chang Shengzhen Zhou Zhiyong Wu Qi Fan | 2016 | Frontiers of Environmental Science & Engineering2016,10,6: | 5 |
| 16 | The effect of crack tip environment on crack growth behaviour of a low alloy steel at cathodic potentials in artificial seawater显示文摘The environment at crack tip and its effect on the crack growth behaviour of low alloy steel-E690 steel were studied at cathodic potentials in artificial seawater.The results showed that the micro environment at crack tip and crack growth behaviour were related to the electrochemical reactions at crack tip,which were affected by the stress state and applied potentials.The crack tip environment was acidified under cyclic loading,resulting from the crack tip anodic dissolution reaction and corresponding hydrolysis reaction.Because of the hydrogen evolution and the inhibited anodic dissolution inside the crack,the crack tip p H increases as the cathodic potential decreases.The effect of cathodic potentials on the electrochemical reactions caused the variation of the hydrogen content,which influenced the crack growth rate because the crack growth behaviour was controlled by hydrogen embrittlement mechanism.This resulted in a fact that with the negative decrease of potential,the crack growth rate first decreased and then increased,with the minimum rate at-0.75 V.And the crack growth path exhibited transgranular fracture. | Yong Li Zhiyong Liu Endian Fan Zhongyu Cui Jinbin Zhao | 2020 | Journal of Materials Science & Technology2020,54,19: | 5 |
| 17 | A Novel Chimeric Mitochondrial Gene Confers Cytoplasmic Effects on Seed Oil Content in Polyploid Rapeseed (Brassica napus)显示文摘Cytoplasmic effects (CEs) have been discovered to influence a diverse array of agronomic traits in crops, and understanding the underlying mechanisms can help accelerate breeding programs. Seed oil content (SOC) is of great agricultural, nutritional, and economic importance. However, the genetic basis of CEs on SOC (CE-SOC) remains enigmatic. In this study, we use an optimized approach to sequence the cytoplasmic (plastid and mitochondrial) genomes of allotetraploid oilseed rape (Brassica napus) cultivars, 51218 and 56366, that bear contrasting CE-SOC. By combining comparative genomics and genome-wide transcriptome analysis, we identify mitochondria-encoded orf188 as a potential CE-SOC determinant gene. Functional analyses in the model system Arabidopsis thaliana and rapeseed demonstrated that orf188 governs CE-SOC and could significantly increase SOC, strikingly, through promoting the yield of ATP. Consistent with this finding, transcriptional profiling with microarray and RNA sequencing revealed that orf188 affects transcriptional reprogramming of mitochondrial energy metabolism to facilitate ATP production. Intriguingly, orf188 is a previously uncharacterized chimeric gene, and the presence of this genetic novelty endows rapeseed with positive CE-SOC. Our results shed light on the molecular basis of CEs on a key quantitative trait in polyploid crops and enrich the theory of maternal control of oil content, providing new scientific guidance for breeding high-oil rapeseed germplasms. | Jun Liu Wanjun Hao Jing Liu Shihang Fan Wei Zhao Linbing Deng Xinfa Wang Zhiyong Hu Wei Hua Hanzhong Wang | 2019 | Molecular Plant2019,12,4: | 5 |
| 18 | Challenges and Prospects of Nanopillar-Based Solar Cells显示文摘Materials and device architecture innovations are essential for further enhancing the performance of solar cells while potentially enabling their large-scale integration as a viable source of alternative energy.In this regard,tremendous research has been devoted in recent years with continuous progress in the field.In this article,we review the recent advancements in nanopillar-based photovoltaics while discussing the future challenges and prospects.Nanopillar arrays provide unique advantages over thin films in the areas of optical properties and carrier collection,arising from their three-dimensional geometry.The choice of the material system,however,is essential in order to gain the advantage of the large surface/interface area associated with nanopillars with the constraints different from those of the thin film devices. | Zhiyong Fan Daniel J.Ruebusch Asghar A.Rathore Rehan Kapadia Onur Ergen Paul W.Leu Ali Javey | 2009 | Nano Research2009,2,11: | 5 |
| 19 | Application in prestiction friction compensation for angular velocity loop of inertially stabilized platforms显示文摘To overcome the influence of the nonlinear friction on the gimbaled servo-system of an inertial stabilized platforms(ISPs) with DC motor direct-drive, the methods of modeling and compensation of the nonlinear friction are proposed. Firstly, the inapplicability of LuGre model when trying to interpret the backward angular displacement in the prestiction regime is observed experimentally and the reason is deduced theoretically. Then, based on the dynamic model of direct-drive ISPs, a modified LuGre model is proposed to describe the characteristic of the friction in the prestiction regime. Furthermore, the state switch condition of the three friction regimes including presliding, gross sliding and prestiction is presented. Finally, a composite compensation controller including a nonlinear friction observer and a feedforward compensator based on the novel LuGre model is designed to restrain the nonlinear friction and to improve the control precision. Experimental results indicate that compared with those of the conventional proportion–integration–differentiation(PID) control method and the PID plus LuGre model-based friction compensation method, the dwell-time has decreased from 0.2 s to almost 0 s, the position error decreased to 86.7%and the peak-to-peak value of position error decreased to 80% after the novel compensation controller is added. It concludes that the composite compensation controller can greatly improve the control precision of the dynamic sealed ISPs. | Zhang Zhiyong Li Zhiqiang Zhou Qingkun Zhang Lianchao Fan Dapeng | 2014 | Chinese Journal of Aeronautics2014,27,3: | 5 |
| 20 | Performance improvement of solution-processed CdS/CdTe solar cells with a thin compact TiO_2 buffer layer显示文摘The device performance of CdS/CdTe solar cells largely depends on not only the back ohmic contact, but also the conformality of Cd S window layer coating. In order to reduce the light absorption loss in Cd S, the Cd S thickness is usually less than 100 nm. However, pinholes in Cd S and non-conformal coverage of Cd S on transparent conducting oxide layer will cause shunting thus leading to device performance degradation and failure. In this paper, low-temperature and low-cost fabrication methods, i.e., chemical bath deposition and electrochemical deposition, were used to deposit Cd S and Cd Te, respectively. It was found that the yield of device was around 20 % due to shunting. In order to alleviate this problem, a compact layer of TiO2 was inserted between the fluorine-doped tin oxide and Cd S as a buffer layer. The thickness effect of TiO2 was studied and showed that devices with thin(20 nm thickness) TiO2 performed better than the counterparts with thick layers. It was discovered that device yield improved to 80 % and stability in air substantially improved with TiO2 layer. | Aashir Waleed Qianpeng Zhang Mohammad Mahdi Tavakoli Siu-Fung Leung Leilei Gu Jin He Xiaoliang Mo Zhiyong Fan | 2016 | Science Bulletin2016,61,1: | 4 |