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| 1 | One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system显示文摘 | Haifeng Wan Chunjing Feng Fei Teng Shihua Yang Baoyang Hu Yuyu Niu Andy Peng Xiang Weizhen Fang Weizhi Ji Wei Li Xiaoyang Zhao Qi Zhou | 2015 | Cell Research2015，25，2： | 39 |
| 2 | Apoptosis and Proinflammatory Cytokine Responses of Primary Mouse Microglia and Astrocytes Induced by Human H1N1 and Avian H5N1 Influenza Viruses显示文摘Patients with an influenza virus infection can be complicated by acute encephalopathy and encephalitis. To investigate the immune reactions involved in the neurocomplication,mouse microglia and astrocytes were isolated,infected with human H1N1 and avian H5N1 influenza viruses,and examined for their immune responses. We observed homogeneously distributed viral receptors,sialic acid (SA)-α2,3-Galactose (Gal) and SA-α2,6-Gal,on microglia and astrocytes. Both viruses were replicative and productive in microglia and astrocytes. Virus-induced apoptosis and cytopathy in infected cells were observed at 24 h post-infection (p.i.). Expression of IL-1β,IL-6 and TNF-α mRNA examined at 6 h and 24 h p.i. was up-regulated,and their expression levels were considerably higher in H5N1 infection. The amounts of secreted proinflammatory IL-1β,IL-6 and TNF-α at 6 h and 24 h p.i. were also induced,with greater induction by H5N1 infection. This study is the first demonstration that both human H1N1 and avian H5N1 influenza viruses can infect mouse microglia and astrocytes and induce apoptosis,cytopathy,and proinflammatory cytokine production in them in vitro. Our results suggest that the direct cellular damage and the consequences of immunopathological injury in the CNS contribute to the influenza viral pathogenesis. | Gefei Wang Juan Zhang Weizhong Li Yun Su Yuanli Gao Heng Zhang Guimei Lin Xiaoyang Jiao Kangsheng Li | 2008 | Cellular & Molecular Immunology2008，5，2： | 28 |
| 3 | Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells显示文摘导致的 pluripotent 干细胞(iPSCs ) 的产生为心疾病,屏蔽的药和潜在的自体同源的心脏的新生的调查打开了新大街。然而,他们的申请被导出 iPSC 的 cardiomyocytes (iPS 厘米) 的低效的心脏的区别,高写在行间可变性,和差的成熟妨碍。为 iPSCs 的心脏的区别和成熟识别有效 inducers 并且阐明机制,我们系统地在各种各样的鼠科的(m) iPSCs 上屏蔽了十六 cardiomyocyte inducers 并且发现没有自发的心脏性的潜力,仅仅维生素酸(AA ) 一致地并且要用体力地包括八提高了十一根线的心脏的区别。我们然后优化了治疗条件并且表明了那区别天 2-6,为心脏的祖先房间(CPC ) 的说明的经期,是一批评时间让 AA 生效。这被 AA 增加了表示的事实进一步证实心血管然而并非 mesodermal 标记。显著, AA 处理导致了近似 7.3 褶层(miPSCs ) 和 30.2 褶层(人的 iPSCs ) 在 iPS 厘米的收益扩充。如此的效果经由 MEK-ERK1/2 小径被归因于 CPC 的增长的特定的增加由通过支持骨胶原合成。另外,导致 AA 的 cardiomyocytes 显示出更好的 sarcomeric 组织并且提高了行动潜力和钙 transients 的回答到 β肾上腺素能并且 muscarinic 刺激。这些调查结果证明 AA 是合适的 cardiomyocyte inducer 让 iPSCs 普遍,简单地改进心脏的区别和成熟。这些调查结果也强调由在指导 pluripotent 干细胞的心脏的区别操作细胞外的微型环境刺激 CPC 增长的重要性。 | Nan Cao Zumei Liu Zhongyan Chen Jia Wang Taotao Chen Xiaoyang Zhao Yu Ma Lianju Qin Jiuhong Kang Bin Wei Liu Wang Ying Jin Huang-Tian Yang | 2012 | Cell Research2012，22，1： | 28 |
| 4 | Atg7 is required for acrosome biogenesis during spermatogenesis in mice显示文摘acrosome 是盖住精子原子核的前面的部分并且在授精的过程起一个必要作用的一个专业化细胞器。位于这个 lysosome 相关的细胞器(LRO ) 的生物的续生说下面的分子的机制大部分仍然是未知的。这里,我们显示出房间特定的 Atg7 大美人老鼠是的那个细菌由于在 acrosome 生物的续生说的一个缺点不肥沃并且显示了类似于人的 globozoospermia 的显型;这个繁殖缺点被 intracytoplasmic 精子注射成功地救。而且,在细菌房间的 Atg7 的弄空没影响细菌房间的开发的早阶段,但是精子发生在以后上演,在 Golgi 期间没有通过到保险丝进一个单个 acrosomal 泡的 proacrosomal 泡分阶段执行,它最后导致了不规则或将近 round-headed 精子。Autophagic 流动在弄空 Atg7 的细菌房间被破坏,最后导致 LC3 变化形式的失败到 Golgi 导出仪器的泡。另外, Atg7 部分调整了另一 globozoospermia 相关的蛋白质,联系 Golgi 的 PDZ 卷和卷卷包含主题的蛋白质(GOPC ) ,在 acrosome 生物的续生说期间。最后,任何一个 autophagy 的注射或进睾丸的 lysosome 禁止者导致了类似的显型到细菌的房间特定的 Atg7 大美人老鼠。总的来说,我们的结果揭开为在 acrosome 的生物的续生说的 Atg7 的一个新角色,并且我们提供证据为 acrosome 支持 autolysosome 起源假设。 | Hongna Wang Haifeng Wan Xixia Li Weixiao Liu Qi Chen Yaqing Wang Lin Yang Hongmei Tang Xiujun Zhang Enkui Duan Xiaoyang Zhao Fei Gao Wei Li | 2014 | Cell Research2014，24，7： | 25 |
| 5 | The mechanism and risk factors for immune checkpoint inhibitor pneumonitis in non-small cell lung cancer patients显示文摘Immune checkpoint inhibitors(ICIs)are new and promising therapeutic agents for non-small cell lung cancer(NSCLC).However,along with demonstrating remarkable efficacy,ICIs can also trigger immune-related adverse events.Checkpoint inhibitor pneumonitis(CIP)has been reported to have a morbidity rate of 3%to 5%and a mortality rate of 10%to 17%.Moreover,the incidence of CIP in NSCLC is higher than that in other tumor types,reaching 7%to 13%.With the increased use of ICIs in NSCLC,CIP has drawn extensive attention from oncologists and cancer researchers.Identifying high risk factors for CIP and the potential mechanism of CIP are key points in preventing and monitoring serious adverse events.In this review,the results of our analysis and summary of previous studies suggested that the risk factors for CIP may include previous lung disease,prior thoracic irradiation,and combinations with other drugs.Our review also explored potential mechanisms closely related toCIP,including increasedT cell activity against associated antigens in tumor and normal tissues,preexisting autoantibodies,and inflammatory cytokines. | Xiaoyang Zhai Jian Zhang Yaru Tian Ji Li Wang Jing Hongbo Guo Hui Zhu | 2020 | Cancer Biology & Medicine2020，17，3： | 25 |
| 6 | Ecosystem Health Assessment of Honghu Lake Wetland of China Using Artificial Neural Network Approach显示文摘Honghu Lake,located in the southeast of Hubei Province,China,has suffered a severe disturbance during the past few decades.To restore the ecosystem,the Honghu Lake Wetland Protection and Restoration Demonstration Project(HLWPRDP) has been implemented since 2004.A back propagation(BP) artificial neural network(ANN) approach was applied to evaluatinig the ecosystem health of the Honghu Lake wetland.And the effectiveness of the HLWPRDP was also assessed by comparing the ecosystem health before and after the project.Particularly,12 ecosystem health indices were used as evaluation parameters to establish a set of three-layer BP ANNs.The output is one layer of ecosystem health index.After training and testing the BP ANNs,an optimal model of BP ANNs was selected to assess the ecosystem health of the Honghu Lake wetland.The result indicates that four stages can be identified based on the change of the ecosystem health from 1990 to 2008 and the ecosystem health index ranges from morbidity before the implementation of HLWPRDP(in 2002) to middle health after the implementation of the HLWPRDP(in 2005).It demonstrates that the HLWPRDP is effective and the BP ANN could be used as a tool for the assessment of ecosystem health. | MO Minghao WANG Xuelei WU Houjian CAI Shuming Xiaoyang ZHANG WANG Huiliang | 2009 | Chinese Geographical Science2009，19，4： | 21 |
| 7 | Magnetogenetics: remote non-invasive magnetic activation of neuronal activity with a magnetoreceptor显示文摘Current neuromodulation techniques such as optogenetics and deep-brain stimulation are transforming basic and translational neuroscience. These two neuromodulation approaches are, however, invasive since surgical implantation of an optical fiber or wire electrode is required. Here, we have invented a non-invasive magnetogenetics that combines the genetic targeting of a magnetoreceptor with remote magnetic stimulation. The noninvasive activation of neurons was achieved by neuronal expression of an exogenous magnetoreceptor, an iron-sulfur cluster assembly protein 1(Isca1). In HEK-293 cells and cultured hippocampal neurons expressing this magnetoreceptor, application of an external magnetic field resulted in membrane depolarization and calcium influx in a reproducible and reversible manner, as indicated by the ultrasensitive fluorescent calcium indicator GCa MP6 s.Moreover, the magnetogenetic control of neuronal activity might be dependent on the direction of the magnetic field and exhibits on-response and off-response patterns for the external magnetic field applied. The activation of this magnetoreceptor can depolarize neurons and elicit trains of action potentials, which can be triggered repetitively with a remote magnetic field in whole-cell patch-clamp recording.In transgenic Caenorhabditis elegans expressing this magnetoreceptor in myo-3-specific muscle cells or mec-4-specific neurons, application of the external magnetic field triggered muscle contraction and withdrawal behavior of the worms, indicative of magnet-dependent activation of muscle cells and touch receptor neurons, respectively. The advantages of magnetogenetics over optogenetics are its exclusive non-invasive, deep penetration, long-term continuous dosing, unlimited accessibility, spatial uniformity and relative safety. Like optogenetics that has gone through decade-long improvements, magnetogenetics, with continuous modification and maturation, will reshape the current landscape of neuromodulation toolboxes and will have a broad range of applications to basic and translational neuroscience as well as other biological sciences. We envision a new age of magnetogenetics is coming. | Xiaoyang Long Jing Ye Di Zhao Sheng-Jia Zhang | 2015 | Science Bulletin2015，60，24： | 19 |
| 8 | Recombinant Newcastle disease virus expressing African swine fever virus protein 72 is safe and immunogenic in mice显示文摘African swine fever(ASF) is a lethal hemorrhagic disease that affects wild and domestic swine. The etiological agent of ASF is African swine fever virus(ASFV). Since the first case was described in Kenya in 1921, the disease has spread to many other countries. No commercial vaccines are available to prevent ASF. In this study, we generated a recombinant Newcastle disease virus(r NDV) expressing ASFV protein 72(p72) by reverse genetics and evaluated its humoral and cellular immunogenicity in a mouse model. The recombinant virus, r NDV/p72, replicated well in embryonated chicken eggs and was safe to use in chicks and mice. The p72 gene in r NDV/p72 was stably maintained through ten passages. Mice immunized with r NDV/p72 developed high titers of ASFV p72 specific Ig G antibody, and had higher levels of Ig G1 than IgG2 a. Immunization also elicited T-cell proliferation and secretion of IFN-γ and IL-4. Taken together, these results indicate that r NDV expressing ASFV p72 might be a potential vaccine candidate for preventing ASF. | Xinxin Chen Jifei Yang Yanhong Ji Edward Okoth Bin Liu Xiaoyang Li Hong Yin Qiyun Zhu | 2016 | Virologica Sinica2016，31，2： | 18 |
| 9 | Measuring reliability under epistemic uncertainty:Review on non-probabilistic reliability metrics显示文摘In this paper,a systematic review of non-probabilistic reliability metrics is conducted to assist the selection of appropriate reliability metrics to model the influence of epistemic uncertainty.Five frequently used non-probabilistic reliability metrics are critically reviewed,i.e.,evidencetheory-based reliability metrics,interval-analysis-based reliability metrics,fuzzy-interval-analysisbased reliability metrics,possibility-theory-based reliability metrics(posbist reliability) and uncertainty-theory-based reliability metrics(belief reliability).It is pointed out that a qualified reliability metric that is able to consider the effect of epistemic uncertainty needs to(1) compensate the conservatism in the estimations of the component-level reliability metrics caused by epistemic uncertainty,and(2) satisfy the duality axiom,otherwise it might lead to paradoxical and confusing results in engineering applications.The five commonly used non-probabilistic reliability metrics are compared in terms of these two properties,and the comparison can serve as a basis for the selection of the appropriate reliability metrics. | Kang Rui ZhangQingyuan Zeng Zhiguo Enrico Zio Li Xiaoyang | 2016 | Chinese Journal of Aeronautics2016，29，3： | 18 |
| 10 | Quantum key-recovery attack on Feistel structures显示文摘Post-quantum cryptography has drawn considerable attention from cryptologists on a global scale. At Asiacrypt 2017, Leander and May combined Grover's and Simon's quantum algorithms to break the FX-based block ciphers, which were introduced by Kilian and Rogaway to strengthen DES. In this study,we investigate the Feistel constructions using Grover's and Simon's algorithms to generate new quantum key-recovery attacks on different rounds of Feistel constructions. Our attacks require 2^(0.25nr-0.75n) quantum queries to break an r-round Feistel construction. The time complexity of our attacks is less than that observed for quantum brute-force search by a factor of 2^(0.75n). When compared with the best classical attacks, i.e.,Dinur et al.'s attacks at CRYPTO 2015, the time complexity is reduced by a factor of 2^(0.5n) without incurring any memory cost. | Xiaoyang DONG Xiaoyun WANG | 2018 | Science China(Information Sciences)2018，61，10： | 18 |
| 11 | Phase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells显示文摘Recent progress in chimeric antigen receptor-modified T-cell(CAR-T cell) technology in cancer therapy is extremely promising, especially in the treatment of patients with B-cell acute lymphoblastic leukemia. In contrast, due to the hostile immunosuppressive microenvironment of a solid tumor, CAR T-cell accessibility and survival continue to pose a considerable challenge, which leads to their limited therapeutic efficacy. In this study, we constructed two anti-MUC1 CAR-T cell lines. One set of CAR-T cells contained SM3 single chain variable fragment(sc Fv) sequence specifically targeting the MUC1 antigen and co-expressing interleukin(IL) 12(named SM3-CAR). The other CAR-T cell line carried the SM3 sc Fv sequence modified to improve its binding to MUC1 antigen(named p SM3-CAR) but did not co-express IL-12. When those two types of CAR-T cells were injected intratumorally into two independent metastatic lesions of the same MUC1+ seminal vesicle cancer patient as part of an interventional treatment strategy, the initial results indicated no side-effects of the MUC1 targeting CAR-T cell approach, and patient serum cytokines responses were positive. Further evaluation showed that p SM3-CAR effectively caused tumor necrosis, providing new options for improved CAR-T therapy in solid tumors. | Fengtao You Licui Jiang Bozhen Zhang Qiang Lu Qiao Zhou Xiaoyang Liao Hong Wu Kaiqi Du Youcai Zhu Huimin Meng Zhishu Gong Yunhui Zong Lei Huang Man Lu Jirong Tang Yafen Li Xiaochen Zhai Xiangling Wang Sisi Ye Dan Chen Lei Yuan Lin Qi Lin Yang | 2016 | Science China(Life Sciences)2016，59，4： | 16 |
| 12 | Dry Friction and Wear Characteristics of Impregnated Graphite in a Corrosive Environment显示文摘Tribological properties of impregnated graphite are greatly influenced by preparation technology and working conditions and it’s highly susceptible to corrosion environmental impacts,but the experimental research about it are few.In this paper,three kinds of impregnated graphite samples are prepared with different degree of graphitization,the tribological properties of these samples in the dry friction environment and in a corrosive environment are analyzed and contrasted.The tribo-test results show that the friction coefficient of samples is reduced and the amount of wear of samples increase when the graphitization degree of samples increases in dry friction condition.While in a corrosive environment(samples are soaked N2O4),the friction coefficient and amount of wear are changed little if the graphitization degree of samples are low.If the degree of graphitization increase,the friction coefficient and amount of wear of samples increase too,the amount of wear is 2 to 3 times as the samples tested in the non-corrosive environment under pv value of 30MPa?m/s.The impregnated graphite,which friction coefficient is stable and graphitization degree is in mid level,such#2,is more appropriate to have a work in the corrosion conditions.In this paper,preparation and tribological properties especially in corrosive environment of the impregnated graphite is studied,the research conclusion can provide an experimental and theoretical basis for the selection and process improvement of graphite materials,and also provide some important design parameters for contact seal works in a corrosive environment. | JIA Qian YUAN Xiaoyang ZHANG Guoyuan DONG Guangneng ZHAO Weigang | 2014 | Chinese Journal of Mechanical Engineering2014，27，5： | 15 |
| 13 | Bioactive hydrogels for bone regeneration显示文摘Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration.While traditional methods for repairing bone defects such as autografts,allografts,and xenografts have been widely used,they all have corresponding disadvantages,thus limiting their clinical use.Despite the development of a variety of biomaterials,including metal implants,calcium phosphate cements(CPC),hydroxyapatite,etc.,the desired therapeutic effect is not fully achieved.Currently,polymeric scaffolds,particularly hydrogels,are of interest and their unique configurations and tunable physicochemical properties have been extensively studied.This review will focus on the applications of various cutting-edge bioactive hydrogels systems in bone regeneration,as well as their advantages and limitations.We will examine the composition and defects of the bone,discuss the current biomaterials for bone regeneration,and classify recently developed polymeric materials for hydrogel synthesis.We will also elaborate on the properties of desirable hydrogels as well as the fabrication techniques and different delivery strategies.Finally,the existing challenges,considerations,and the future prospective of hydrogels in bone regeneration will be outlined. | Xin Bai Mingzhu Gao Sahla Syed Jerry Zhuang Xiaoyang Xu Xue-Qing Zhang | 2018 | Bioactive Materials2018，3，4： | 15 |
| 14 | Effect of Nd on microstructure and mechanical properties of as-extruded Mg-Y-Zr-Nd alloy显示文摘The microstructure and mechanical properties of Mg-Y-Zr-x Nd alloys with 0–2.63 wt% Nd were investigated using optical microscopy, scanning electron microscopy, transmission electron microscopy, X-ray diffraction and tensile testing test. Results indicated that more Mg_(24)Y_5 particles and Mg_(14)Nd_2Y(β) phases were dispersed in the matrix when Nd content increased from 0 wt% to 2.63 wt% in the extruded alloys.Consequently, the nucleation of dynamic recrystallization and the volume fraction of recrystallized grains were promoted obviously. The average grain size can be refined in the range of 4.6–1.3 μm after the addition of 2.63 wt% Nd. The tensile strength of extruded alloys increased with increasing Nd content, and elongation exhibited an opposite change tendency. The extruded alloy sheet with 1.01 wt% Nd demonstrates optimal combination of strength and plasticity, i.e., the ultimate tensile strength, yield strength,and elongation were 273 MPa, 214 MPa, and 24.2%, respectively. Variations in mechanical properties are discussed on the basis of microstructure observations. | Xiaoyang Xu Xianhua Chen Weiwei Du Yuxiao Geng Fusheng Pan | 2017 | Journal of Materials Science & Technology2017，33，9： | 14 |
| 15 | Understanding the China–US trade war:causes,economic impact,and the worst-case scenario显示文摘This paper studies the current trade war between China and the US from a historical standpoint.By comparing the ongoing trade war with similar trade conflicts in history,we reveal three major causes,with varying degrees of importance,from both economic and political perspectives.The trade war can principally be attributed to trade imbalances,the US midterm elections and rivalry over global economic dominance.As the fundamental conflicts between China and the US cannot be easily resolved,we hold a pessimistic view on the complete settlement of the trade war.In this paper,we perform a scenario analysis,which shows that in the worst-case scenario,China will suffer a 1.1%decrease in employment and a 1%GDP loss,which are not negligible,but manageable for China. | Terence Tai Leung Chong Xiaoyang Li | 2019 | Economic and Political Studies2019，7，2： | 14 |
| 16 | Quantum cryptanalysis on some generalized Feistel schemes显示文摘Post-quantum cryptography has attracted much attention from worldwide cryptologists. In ISIT 2010, Kuwakado and Morii gave a quantum distinguisher with polynomial time against 3-round Feistel networks. However, generalized Feistel schemes(GFS) have not been systematically investigated against quantum attacks. In this paper, we study the quantum distinguishers about some generalized Feistel schemes.For d-branch Type-1 GFS(CAST256-like Feistel structure), we introduce(2 d-1)-round quantum distinguishers with polynomial time. For 2 d-branch Type-2 GFS(RC6/CLEFIA-like Feistel structure), we give(2 d + 1)-round quantum distinguishers with polynomial time. Classically, Moriai and Vaudenay proved that a 7-round 4-branch Type-1 GFS and 5-round 4-branch Type-2 GFS are secure pseudo-random permutations. Obviously, they are no longer secure in quantum setting. Using the above quantum distinguishers, we introduce generic quantum key-recovery attacks by applying the combination of Simon's and Grover's algorithms recently proposed by Leander and May. We denote n as the bit length of a branch. For(d^2-d + 2)-round Type-1 GFS with d branches, the time complexity is 2^((1/2d^2-3/2d+2)·n/2), which is better than the quantum brute force search(Grover search) by a factor 2^((1/4d^2+1/4d)n). For 4 d-round Type-2 GFS with d2 branches, the time complexity is 2^((d^2n)/2(, which is better than the quantum brute force search by a factor 2^((3d^2n)/2). | Xiaoyang DONG Zheng LI Xiaoyun WANG | 2019 | Science China(Information Sciences)2019，62，2： | 12 |
| 17 | Clinical classification and treatment of leukokeratosis of the vocal cords显示文摘 | MA Li-jing WANG Jun XIAOYang YE Jing-ying XU Wen YANG Qing-wen | 2013 | Chinese Medical Journal2013，，18： | 12 |
| 18 | Security value based expansion planning of power system with integration of large-scale wind power显示文摘Concerning the integration of large-scale wind power,an integrated model of generation and transmission expansion planning is proposed based on the assessment of the value of steady state and dynamic security.In the assessment of security value,the unit commitment simulation based on the predicted hourly load and wind power output data in the planning horizon is used to evaluate the costs of preventive control,emergency control and social losses due to the uncertainty of load and wind power.The cost of preventive control consists of the fuel cost of power generation,the environmental cost and the load shedding cost.This not only provides a systematic method of security assessment of power system expansion planning schemes,but also broadens the perspective of power system planning from the technology and economic assessment to the measure of the whole social value.In the assessment process,the preventive control and emergency control of cascading failures are also presented,which provides a convincing tool for cascading failure analysis of planning schemes and makes the security assessment more comprehensive and reasonable.The proposed model and method have been demonstrated by the assessment of two power system planning schemes on the New England 10-genarator 39-bus System.The importance of considering the value of security and simulating hourly system operation for the planning horizon,in expansion planning of power system with integration of large-scale wind power,has been confirmed. | YU YIXin WANG JingRan LV XiaoYang | 2012 | Science China(Technological Sciences)2012，55，7： | 11 |
| 19 | A Reconfigurable Block Cryptographic Processor Based on VLIW Architecture显示文摘An Efficient and flexible implementation of block ciphers is critical to achieve information security processing.Existing implementation methods such as GPP,FPGA and cryptographic application-specific ASIC provide the broad range of support.However,these methods could not achieve a good tradeoff between high-speed processing and flexibility.In this paper,we present a reconfigurable VLIW processor architecture targeted at block cipher processing,analyze basic operations and storage characteristics,and propose the multi-cluster register-file structure for block ciphers.As for the same operation element of block ciphers,we adopt reconfigurable technology for multiple cryptographic processing units and interconnection scheme.The proposed processor not only flexibly accomplishes the combination of multiple basic cryptographic operations,but also realizes dynamic configuration for cryptographic processing units.It has been implemented with0.18μm CMOS technology,the test results show that the frequency can reach 350 MHz.and power consumption is 420 mw.Ten kinds of block and hash ciphers were realized in the processor.The encryption throughput of AES,DES,IDEA,and SHA-1 algorithm is1554 Mbps,448Mbps,785 Mbps,and 424 Mbps respectively,the test result shows that our processor's encryption performance is significantly higher than other designs. | LI Wei ZENG Xiaoyang NAN Longmei CHEN Tao DAI Zibin | 2016 | China Communications2016，13，1： | 11 |
| 20 | Toward a research framework to conceptualize data as a factor of production:The data marketplace perspective显示文摘The widespread use of machine learning techniques and artificial intelligence algorithms has highlighted the strategic role of data.To acquire data for training algorithms and eventually empowering the digital transformation,data marketplaces are often required to support and coordinate cross-organizational data transactions.However,the prior industry practices have suggested that the transaction costs in the data marketplaces are severely high,and the supporting infrastructure is far from mature.This paper proposes a data attributes-affected data exchange(DADE)conceptual model to understand the challenges and directions for developing data marketplaces.Specifically,our model framework is built upon two dimensions,data lifecycle maturity and data asset specificity.Based on the DADE model,we propose four approaches for developing data marketplaces and discuss future research directions with an overview of computational methods as potential technical solutions. | Lihua Huang Yifan Dou Yezheng Liu Jinzhao Wang Gang Chen Xiaoyang Zhang Runyin Wang | 2021 | Fundamental Research2021，1，5： | 11 |
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