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| 1 | Rupture segmentation and slip partitioning of the mid-eastern part of the Kunlun Fault,north Tibetan Plateau显示文摘The Kunlun Fault,an active fault on the border between the Bayan Har and Kunlun-Qaidam blocks,is one of the major left lateral strike-slip faults in the Tibetan Plateau.Previous research has not reached a consensus on agreeable slip rates along much of its length and the slip rate gradient along the eastern part,both of which play critical roles in a range of models for the eastward extrusion and thickened crust of the Tibetan Plateau.New slip rates have been determined at sites along the eastern part of the Kunlun Fault by dating deposits and measuring atop displaced fluvial terrace risers.Field investigations and interpretation of satellite images reveal geometrical features of the fault and the late Quaternary offset,new earthquake ruptures and surface-rupturing segmentation,from which long-term slip rates and earthquake recurrence intervals on the fault are estimated.The tectonic geomorphology method has determined that the long-term horizontal slip rates on the Tuosuohu,Maqin and Maqu segments from west to east are 11.2±1,9.3±2,and 4.9±1.3 mm/a while their vertical slip rates are 1.2±0.2,0.7±0.1,and 0.3 mm/a in the late Quaternary.Results indicate that the slip rates regularly decrease along the eastern ~300 km of the fault from >10 to <5 mm/a.This is consistent with the decrease in the gradient such that at the slip rate break point is at the triple point intersection with the transverse fault,which in turn is transformed to the Awancang Fault.The vector decomposition for this tectonic transformation shows that the western and eastern branches of the Awancang Fault fit the slip-partitioning mode.The slip rate of the southwestern wall is 4.6 mm/a relative to the northeastern wall and the slip direction is 112.1°.The mid-eastern part of the Kunlun Fault can be divided into three independent segments by the A'nyêmaqên double restraining bend and the Xigongzhou intersection zone,which compose the surface rupture segmentation indicators for themselves as well as the ending point of the 1937 M7.5 Tuosuohu earthquake.The average recurrence interval of the characteristic earthquakes are estimated to be 500-1000 a,respectively.The latest earthquake ruptures occurred in AD 1937 on the western Tuosuohu segment,as compared to ~514-534 a BP on the Maqin segment,and ~1055 to 1524 a BP on the Maqu segment.This may indicate a unidirectional migration for surface rupturing earthquakes along the mid-eastern Kunlun Fault related to stress triggered between these segments.Meanwhile,the long-term slip rate is obtained through the single event offset and the recurrence interval,which turn out to be the same results as those determined by the offset tectonic geomorphology method,i.e.,the decreasing gradient corresponds to the geometrical bending and the fault's intersection with the transverse fault.Therefore,the falling slip rate gradient of the mid-eastern Kunlun Fault is mainly caused by eastward extension of the fault and its intersection with the transverse fault. | LI ChenXia XU XiWei WEN XueZe ZHENG RongZhang CHEN GuiHua YANG Hu AN YanFen GAO Xiang | 2011 | Science China Earth Sciences2011，54，11： | 33 |
| 2 | Visible light-induced N-doped TiO_2 nanoparticles for the degradation of microcystin-LR显示文摘N-doped nano-crystalline TiO2 powders have been synthesized by the sol-gel method.The shape and crystal structure of the resulting N-doped TiO2 were investigated by X-ray Photoelectron Spectroscopy (XPS),X-ray spectroscopy (XRD),Transmission Electron Microscopy (TEM) and UV-vis reflection spectrum.The results showed that doping TiO2 with nitrogen can lower its band gap and apparently shift its optical response to the visible region.Under the visible light (λ> 420 nm) irradiation,the MC-LR was degraded by the synthesized N-TiO2 nano-material.The variation of MC-LR amount and its intermediates were detected by high performance liquid chromatography (HPLC) and LC-MS,respectively.The mineralization of MC-LR was determined by total organic carbon (TOC) analysis.Simultaneously,transient oxidative species generated during photocatalysis were tracked by electron spin resonance (ESR) and Peroxidase method.All these results indicated that visible-light excited N-TiO2 can activate molecular oxygen and thereby achieve degradation of MC-LR completely within 14 h.The removal of 59% of TOC was achieved after 20 h irradiation.The major oxidative species in the system were hydroxyl radical (·OH) and H2O2.13 Kinds of intermediates were primarily identified in the process.Based on these results,a reasonable conclusion was drawn for the degradation of MC-LR wherein its four positions are easy to be attacked by the photo-generated OH radical followed by the hydrolyzation of peptides. | YANG Jing,CHEN DengXia,DENG AnPing,FANG YanFen,LUO GuangFu,LI DeJiang,LI RuiPing & HUANG YingPing Alan G.MacDiarmid Research Institute of Renewable Energy,China Three Gorges University,Yichang 443000,China | 2010 | Science China Chemistry2010，53，8： | 12 |
| 3 | The effect of nanohybrid materials on the pour-point and viscosity depressing of waxy crude oil显示文摘The pipeline transportation of waxy crude oil is a problem both at home and abroad.In this paper,a novel nanohybrid pour-point depressant (PPD) was used to decrease the pour point and viscosity of waxy crude oil.The pour point and apparent viscosity of waxy crude oil was decreased significantly upon addition of the nanohybrid PPD,and the long-term stability of the nanohybrid PPD was superior to that of a conventional ethylene-vinyl acetate copolymer PPD.Polarized optical microscopy and X-ray diffraction were used to study the effect of the nanohybrid PPD on the crystallization of crude oil.Addition of the nanohybrid PPD reduced the amount of wax crystals,prevented their aggregation,and reduced the temperature at which the crude oil started to crystallize.The significant effect of this nanohybrid PPD on the pour point and viscosity depressing of crude oil is of great importance for facilitating the safe,efficient and energy-minimized transportation of waxy crude oil. | WANG Feng ZHANG DongMin DING YanFen ZHANG LiXin YANG MingShu JIANG BaoLiang ZHANG ShiMin AI MuYang LIU GuangWen ZHI ShuJie HUO LianFeng OUYANG Xin LI Li | 2011 | Chinese Science Bulletin2011，56，1： | 9 |
| 4 | Inflammasome activation in mouse inner ear in response to MCMV induced hearing loss显示文摘Objective: To identify presence of inflammasome activated in mouse cochlea with sensorineural hearing loss(SNHL) caused by cytomegalovirus(CMV) infection.Method: MCMV was injected into the right cerebral hemisphere in neonatal BALB/c mice at 2000 pfu virus titers. Auditory brainstem responses(ABRs) were tested to evaluate hearing at 21 days. Histopathological studies were conducted to confirm localizations of MCMV infected cells in the inner ear. Expression of inflammasome related factors was assessed by immunofluorescence, Quantitative real-time PCR and Western blotting.Results: In the mouse model of CMV induced SNHL, inflammasome related kinase Caspase-1 and downstream inflammatory factor IL-1b and IL-18 were found increased and activated after CMV infection in the cochlea. These factors could further up-regulate expression of IL-6 and TNFa. These inflammatory factors are neurotoxicity and may contribute to hearing impairment. Furthermore, we also detected significantly increased AIM2 protein that accumulated in the SGN of cochleae with CMV infection.Significance: We have shown that inflammasome as a novel inherent immunity mechanism may contribute to hearing impairment.Conclusion: Our data indicate that imflammasome assemble in mouse inner ear in response to CMV infection. We have revealed a novel pathology event in CMV induced SNHL involving activation of inflammasome in mouse cochlea. Additionally, we have shown that inflammasome may be a novel target for prevention and treatment of CMV related SNHL. | Xi Shi Yanfen Dong Ya Li ZenLu Zhao Huan Li Shiwei Qiu Yaohan Li Weiwei Guo Yuehua Qiao | 2015 | Journal of Otology2015，10，4： | 9 |
| 5 | Comparative study on skin temperature response to menstruation at acupuncture points in healthy volunteers and primary dysmenorrhea patients显示文摘OBJECTIVE:To assess skin temperature response to menstruation at acupuncture points in primary dysmenorrhea(PD) patients and healthy volunteers so as to explore acupuncture point specificity in reflecting diseases in the light of skin temperature.METHODS:Fifty-two PD patients and 49 healthy volunteers were recruited.Skin temperature measurements were performed with a skin temperature assessment device at 10 points.Absolute difference between skin temperature of the same point on the left and right side is used as main outcome measure.RESULTS:On the first day of menstruation, when menstrual pain attacking in PD patients, a significant increase in skin temperature difference was detected at Taixi(KI 3) compared with the healthy group(P < 0.01).A significant reduction in skin temperature difference was detected at Taixi(KI 3) in the first day of menstruation compared with those values in the third day after menstruation(P < 0.01)in the healthy group.On the third day after menstruation, a significant reduction in skin temperature difference was found at Zhongdu(LR 6) in PD group compared with the healthy group(P < 0.05).No significant differences of skin temperature were detected at other points(P > 0.05).CONCLUSION:The skin temperature difference at menstruation-relevant points in PD patients did not all change significantly more than those in women without PD.Significant difference was only found in Taixi(KI 3), the Yuan-source point of Kidney meridian. | She Yanfen Ma Liangxiao Zhu Jiang Qi Conghui Wang Yanxia Tang Ling Li Chunhua Yuan Hongwen Liu Yuqi Song Jiashan | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 8 |
| 6 | Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry显示文摘A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer(GC-MS/MS) for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans(PCDD/Fs) and dioxin-like polychlorinated biphenyls(DL-PCBs) in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level(10 pg mL^(-1) for 2,3,7,8-TCDD/F), as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5–200 ng mL^(-1) for PeCDD/F and 0.2–2000 ng mL^(-1) for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018–0.17 pg g^(-1) to 0.13–0.36 pg g^(-1), respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation. | Huizhong Sun Pu Wang Honghua Li Yingming Li Shucheng Zheng Julius Matsiko Yanfen Hao Weiwei Zhang Dou Wang Qinghua Zhang | 2017 | Science China Chemistry2017，60，5： | 6 |
| 7 | PKM2 promotes reductive glutamine metabolism显示文摘Objective:Pyruvate kinases M(PKM),including the PKM1 and PKM2 isoforms,are critical factors in glucose metabolism.PKM2promotes aerobic glycolysis,a phenomenon known as'the Warburg effect'.The purpose of this study was to identify the roles of PKM2 in regulating cellular metabolism.Methods:The CRISPR/Cas9 system was used to generate the PKM-knockout cell model to evaluate the role of PKM in cellular metabolism.Lactate levels were measured by the Vitros LAC slide method on an autoanalyzer and glucose levels were measured by the autoanalyzer AU5800.The metabolism of ^(13)C_6-glucose or ^(13)C_5-glutamine was evaluated by liquid chromatography/mass spectrometry analyses.The effects of PKM on tumor growth were detected in vivo in a tumor-bearing mouse model.Results:We found that both PKM1 and PKM2 enabled aerobic glycolysis,but PKM2 converted glucose to lactate much more efficiently than PKM1.As a result,PKM2 reduced glucose levels reserved for intracellular utilization,particularly for the production of citrate,and thus increased theα-ketoglutarate/citrate ratio to promote the generation of glutamine-derived acetylcoenzyme A through the reductive pathway.Furthermore,reductive glutamine metabolism facilitated cell proliferation under hypoxia conditions,which supports in vivo tumor growth.In addition,PKM-deletion induced a reverse Warburg effect in tumorassociated stromal cells.Conclusions:PKM2 plays a critical role in promoting reductive glutamine metabolism and maintaining proton homeostasis.This study is helpful to increase the understanding of the physiological role of PKM2 in cancer cells. | Miao Liu Yuanyuan Wang Yuxia Ruan Changsen Bai Li Qiu Yanfen Cui Guoguang Ying Binghui Li | 2018 | Cancer Biology & Medicine2018，15，4： | 6 |
| 8 | Immobilization of acetylcholinesterase on one-dimensional gold nanoparticles for detection of organophosphorous insecticides显示文摘This paper reports a simple method for immobilization of acetylcholinesterase (AChE) on one-dimensional (1D) gold (Au) nanoparticles for detection of organophosphorous (OP) insecticides. 1D Au nanoparticles were prepared by electrodeposition in the pores of an alumina template which was subsequently removed by 2.0 M NaOH solution. They were characterized by XRD and FESEM. The immobilized AChE retained its biological activity and catalyzed the hydrolysis of acetylthiocholine to form thiocholine, which was subsequently oxidized to produce detectable signals. Based on the inhibition toward the enzymatic activity of AChE by OP insecticides, sensitive detection of methamidophos (an OP insecticide) was performed. Under optimal conditions, the sensors could be used for the determination of methamidophos ranging from 0.004 to 24 μg/mL with the detection limit of 0.001 μg/mL. The developed OP insecticide biosensors exhibited satisfactory stability and reproducibility. This work demonstrated that 1D Au nanoparticles could serve as an ideal carrier for immobilization of AChE to fabricate the corresponding biosensor. | LI YanRong, GAN ZhiYong, LI YanFen, Liu Qian, BAO JianChun, DAI ZhiHui & HAN Min Jiangsu Key Laboratory of Biofunctional Materials College of Chemistry and Environmental Science, Nanjing Normal University, Nanjing 210097, China | 2010 | Science China Chemistry2010，53，4： | 6 |
| 9 | Diversity of methanotrophs in Zoige wetland soils under both anaerobic and aerobic conditions显示文摘Zoige wetland is one of the most important methane emission centers in China. The oxidation of methane in the wetland affects global warming, soil ecology and atmospheric chemistry. Despite their global significance, microorganisms that consume methane in Zoige wetland remain poorly characterized. In this study, we investigated methanotrophs diversity in soil samples from both anaerobic site and aerobic site in Zoige wetland using pmoA gene as a molecular marker. The cloning library was constructed according to the pmoA sequences detected. Four clusters of methanotrophs were detected. The phylogenetic tree showed that all four clusters detected were affiliated to type I methanotrophs. Two novel clusters (cluster 1, cluster 2) were found to relate to none of the recognized genera of methanotrophs. These clusters have no cultured representatives and reveal an ecological adaptation of particular uncultured methanotrophs in Zoige wetland. Two clusters were belonging to Methylobacter and Methylococcus separately. Denaturing gradient gel electrophoresis gel bands pattern retrieved from these two samples revealed that the community compositions of anaerobic soil and aerobic soil were different from each other while anaerobic soil showed a higher metanotrophs diversity. Real-time PCR assays of the two samples demonstrated that aerobic soil sample in Zoige wetland was 1.5 times as much copy numbers as anaerobic soil. These data illustrated that methanotrophs are a group of microorganisms influence the methane consumption in Zoige wetland. | Juanli Yun Anzhou Ma Yaoming Li Guoqiang Zhuang Yanfen Wang Hongxun Zhang | 2010 | Journal of Environmental Sciences2010，22，8： | 6 |
| 10 | Pore Structure Regulation of Carboxyethylated Microfibrillated Cellulose Films显示文摘Carboxyethylation is a recent chemical pretreatment for preparation of microfibrillated cellulose(MFC).The carboxyethylated MFC film prepared by coating method has compact structure and high mechanical properties.In order to expand its application,three approaches including using organic solvents,different drying methods and cationic additives,have been adopted in this paper to enrich and regulate the pore structure of MFC film.The results show that all the approaches can improve the pore structure but decrease the mechanical properties of MFC film.When organic solvents such as ethanol,isopropanol and n-butanol were used to replace the water in MFC suspension or pre-dried MFC film,the pore structure of films were increased.Additionally,the film obtained by freeze-drying or air-drying after freezing in liquid nitrogen or freezer has high porosity but poor strength.The best drying process is to rewet dry MFC film,freeze in liquid nitrogen and then freeze-dry.Moreover,the addition of cationic polyelectrolytes or alkene ketone dimer(AKD)in MFC suspension can also significantly increase the film's porosity.Through the above approaches,the porosity of carboxyethylated MFC film can be regulated between 20% and 90%. | Meican Li Jinghuan Chen Jingang Liu Zehong Xu Yanqun Su Ruijuan Zhang Yanfen Du | 2020 | Paper And Biomaterials2020，5，2： | 5 |
| 11 | Green and efficient degradation of cefoperazone sodium by Bi_(4)O_(5)Br_(2) leading to the production of non-toxic products:Performance and degradation pathway显示文摘Photocatalytic process represents a promising approach to overcome the pollution challenge associated with the antibiotics-containing wastewater.This study provides a green,efficient and novel approach to remove cephalosporins,particularly cefoperazone sodium(CFP).Bi_(4)O_(5)Br_(2) was chosen for the first time to systematically study its degradation for CFP,including the analysis of material structure,degradation performance,the structure and toxicity of the transformation products,etc.The degradation rate results indicated that Bi_(4)O_(5)Br_(2) had an excellent catalytic activity leading to 78%CFP removal compared with the pure BiOBr(38%)within 120 min of visible light irradiation.In addition,the Bi_(4)O_(5)Br_(2) presents high stability and good organic carbon removal efficiency.The effects of the solution p H(3.12-8.75)on catalytic activity revealed that CFP was mainly photocatalyzed under acidic conditions and hydrolyzed under alkaline conditions.Combined with active species and degradation product identification,the photocatalytic degradation pathways of CFP by Bi_(4)O_(5)Br_(2) was proposed,including hydrolysis,oxidation,reduction and decarboxylation.Most importantly,the identified products were all hydrolysis rather than oxidation byproducts transformed from the intermediate ofβ-lactam bond cleavage in CFP molecule,quite different from the mostly previous studies.Furthermore,the final products were demonstrated to be less toxic through the toxicity analysis.Overall,this study illustrates the detailed mechanism of CFP degradation by Bi_(4)O_(5)Br_(2) and confirms Bi_(4)O_(5)Br_(2) to be a promising material for the photodegradation of CFP. | Yingying Chen Ruiping Li Yan Gu Hailin Tian Yingping Huang Junsong Chen Yanfen Fang Changying Yang | 2021 | Journal of Environmental Sciences2021，33，2： | 4 |
| 12 | A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy显示文摘The combination of Ce6,an acknowledged photosensitizer,and TPL,a natural anticancer agent,has been demonstrated as a useful strategy to reinforce the tumor growth suppression,as well as decrease the systemic side effects compared with their monotherapy.However,in view of the optimal chemo-photodynamic combination efficiency,there is still short of the feasible nanovehicle to steadily co-deliver Ce6 and TPL,and stimuli-responsively burst release drugs in tumor site.Herein,we described the synergistic antitumor performance of a pH-sensitive supramolecular nanosystem,mediated by the host–guest complexing betweenβ-CD and acid pH-responsive amphiphilic co-polymer mPEG-PBAE-mPEG,showing the shell–core structural micelles with the tightβ-CD layer coating.Both Ce6 and TPLwere facilely co-loaded into the spherical supramolecular NPs(TPL+Ce6/NPs)by one-step nanoprecipitation method,with an ideal particle size(156.0 nm),acid pH-responsive drug release profile,and enhanced cellular internalization capacity.In view of the combination benefit of photodynamic therapy and chemotherapy,as well as co-encapsulation in the fabricated pH-sensitive supramolecular NPs,TPL+Ce6/NPs exhibited significant efficacy to suppress cellular proliferation,boost ROS level,lower MMP,and promote cellular apoptosis in vitro.Particularly,fluorescence imaging revealed that TPL+Ce6/NPs preferentially accumulated in the tumor tissue area,with higher intensity than that of free Ce6.As expected,upon 650-nm laser irradiation,TPL+Ce6/NPs exhibited a cascade of amplified synergistic chemo-photodynamic therapeutic benefits to suppress tumor progression in both hepatoma H22 tumor-bearingmice and B16 tumor-bearingmice.More importantly,lower systemic toxicitywas found in the tumor-bearingmice treated with TPL+Ce6/NPs.Overall,the designed supramolecular TPL+Ce6/NPs provided a promising alternative approach for chemo-photodynamic therapy in tumor treatment. | Yihan Wu Jingjing Li Xuemei Zhong Jinfeng Shi Yanfen Cheng Chenglin He Jiaxin Li Liang Zou Chaomei Fu Meiwan Chen Jinming Zhang Huile Gao | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，2： | 4 |
| 13 | Kinetic investigation of in situ growth of CdMoO_4 nano-octahedra显示文摘CdMoO4 nano-octahedra were grown in situ at room temperature by reverse-microemulsion.Energy evolution from this growth process was monitored using microcalorimetry.The microcalorimetric heat flow (MCHF) curve showed a characteristic endothermic peak for the initial reaction,and double discontinuous exothermic peaks for the subsequent crystal growth.Combined with complementary characterization techniques,the evolution of morphology and size of the CdMoO4 nano-octahedra were correlated with the MCHF peaks.Calculations based on the microcalorimetric results at 298.15 K provided rate constants of 7.56×10–5 s–1 for the reaction and nucleation process and 1.59×10–4 s–1 for the crystallization process. | LI YanFen JIANG JunYing FAN GaoChao MA YuJie HUANG ZaiYin | 2011 | Chinese Science Bulletin2011，56，3： | 3 |
| 14 | Eco-friendly PVA/Kaolin Clay Coating for Barrier Paper显示文摘The resistance of wood-fiber paper to water, grease, and water vapor is usually attained by immersing the base paper in hydrophobic oil, laminating with a plastic or metal film, or the application of a barrier coating. Oil impregnation and the addition of films may make the paper difficult to recycle or persistent in the environment owing to their strong binding force and nondegradability. Environmental concerns have attracted worldwide attention to eco-friendly barrier coatings. In this study, degradable polyvinyl alcohol(PVA) and kaolin clay pigment were used to prepare coatings that were applied to a base paper. By measuring the barrier properties of the coated paper, including the water absorptiveness(Cobb60 value), Hercules sizing degree, oil resistance(Kit rating), and water vapor transmission rate(WVTR), an optimal coating formulation and process were proposed. To examine the barrier mechanism of the PVA/kaolin clay coating, we characterized the coating microstructures using a scanning electron microscopy(SEM) and a mercury porosimeter. The results showed that the Cobb60 value and water vapor transmission rate of the coated paper decreased by 61.4% and 98.6%, respectively, compared with the base paper, for a pre-coating weight of 0.98 g/m^2 and a top-coating weight of about 3.23 g/m^2. Furthermore, the Hercules sizing degree rose by a factor of 337.2, while the oil resistance(Kit rating) increased from 0 to 12. The optimum drying temperature for a wet coating layer was found to be 170℃, and the optimum weight ratio of PVA to kaolin clay in the coating was determined to be 50∶50. It was assumed that the PVA/kaolin clay coating improved the smoothness of the paper considerably and decreased the pore size by filling the pores on the paper surface and forming an even film, thus enhancing the paper barrier performance. The coated paper also exhibited good repulpability. | YanFen Du JinGang Liu JiaFu Wang YanQun Su HongCai Li BiSong wang RuiJuan Zhang | 2017 | Paper And Biomaterials2017，2，2： | 3 |
| 15 | Vascularized bone regeneration accelerated by 3D-printed nanosilicate-functionalized polycaprolactone scaffold显示文摘Critical oral-maxillofacial bone defects,damaged by trauma and tumors,not only affect the physiological functions and mental health of patients but are also highly challenging to reconstruct.Personalized biomaterials customized by 3D printing technology have the potential to match oralmaxillofacial bone repair and regeneration requirements.Laponite(LAP)nanosilicates have been added to biomaterials to achieve biofunctional modification owing to their excellent biocompatibility and bioactivity.Herein,porous nanosilicate-functionalized polycaprolactone(PCL/LAP)was fabricated by 3D printing technology,and its bioactivities in bone regeneration were investigated in vitro and in vivo.In vitro experiments demonstrated that PCL/LAP exhibited good cytocompatibility and enhanced the viability of bone marrow mesenchymal stem cells(BMSCs).PCL/LAP functioned to stimulate osteogenic differentiation of BMSCs at the mRNA and protein levels and elevated angiogenic gene expression and cytokine secretion.Moreover,BMSCs cultured on PCL/LAP promoted the angiogenesis potential of endothelial cells by angiogenic cytokine secretion.Then,PCL/LAP scaffolds were implanted into the calvarial defect model.Toxicological safety of PCL/LAP was confirmed,and significant enhancement of vascularized bone formation was observed.Taken together,3D-printed PCL/LAP scaffolds with brilliant osteogenesis to enhance bone regeneration could be envisaged as an outstanding bone substitute for a promising change in oral-maxillofacial bone defect reconstruction. | Xiongcheng Xu Long Xiao Yanmei Xu Jin Zhuo Xue Yang Li Li Nianqi Xiao Jing Tao Quan Zhong Yanfen Li Yuling Chen Zhibin Du Kai Luo | 2021 | Regenerative Biomaterials2021，8，6： | 3 |
| 16 | The Progress of CDIO Engineering Education Reform in Several China Universities: A Review显示文摘 | Bai Jianfeng Lei Hu Yanfen Li Zhen Tian Lili Xie Lijun Wang Mingyuan Zhou Jie Guan Huaqing Xie | 2013 | Procedia - Social and Behavioral Sciences2013，，： | 3 |
| 17 | Determination of glucose deficiency-induced cell death by mitochondrial ATP generation-driven proton homeostasis显示文摘 | Yanfen Cui Yuanyuan Wang Miao Liu Li Qiu Pan Xing Xin Wang Guoguang Ying Binghui Li | 2017 | Journal of Molecular Cell Biology2017，9，5： | 3 |
| 18 | Atmospheric levels and distribution of Dechlorane Plus in an E-waste dismantling region of East China显示文摘Atmospheric concentrations of Dechlorane Plus(DP)were investigated in Taizhou,an electronic-waste(E-waste)dismantling region in East China.Passive air samplers with polyurethane foam(PUF)disks were deployed every three months during the sampling period of September 2009-August 2010.The total DP(syn-and anti-DP)concentrations in air ranged from not detected to 277 pg/m^3,with a mean concentration of 53.9 pg/m^3.A generally declining trend of DP levels was found from the E-waste dismantling region to the peripheral areas.The median values of total DP concentrations in autumn,winter,spring and summer were 52.2,28.8,39.7 and 30.1 pg/m^3,respectively.The seasonal variations of DP concentrations were mainly associated with the intensity of E-waste dismantling activities and meteorological conditions.The mean value of anti-DP fractional abundance(f_(anti))was 0.74±0.08,which was consistent with those in the commercial DP products.This study confirmed a significant emission source related to the distribution of atmospheric DP in the E-waste dismantling area and supplied information for the seasonal variation of DP in the atmosphere. | Huizhong Sun Yingming Li Pu Wang Shucheng Zheng Julius Matsiko Dou Wang Weiwei Zhang Yanfen Hao Qinghua Zhang Guibin Jiang | 2017 | Science China Chemistry2017，60，2： | 2 |
| 19 | Outcomes of peripheral blood stem cell transplantation in patients from human leukocyte antigen matched or mismatched unrelated donors显示文摘 | Cao Tingting Li Yanfen Wang Quanshun Li Honghua Bo Jian Zhao Yu Jing Yu Wang Shuhong Zhu Haiyan Dou Liping Jia Bojun Gao Chunji Yu Li Huang Wenrong | 2014 | Chinese Medical Journal2014，，14： | 2 |
| 20 | The chemistry of heavy haze over Urumqi, Central Asia显示文摘 | Juan Li Guoshun Zhuang Kan Huang Yanfen Lin Qiongzhen Wang Yuhong Guo Jinghua Guo Shulong Yu Caixia Cui Joshua S. Fu | 2008 | Journal of Atmospheric Chemistry2008，，1： | 2 |
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