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| 1 | Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells显示文摘Spermatogonial 干细胞(SSC ) 能在移植以后生产众多的男配偶子进接受者睾丸,介绍为基因治疗和修改基因的动物的连续生产的一条珍贵途径。然而, SSC 的成功的基因操作被限制了,部分由于复杂性和当前可得到的基因编辑技术的低效率。这里,我们证明有效基因修正能用 CRISPR-Cas9 系统被介绍进 SSC。我们使用了 CRISPR-Cas9 系统变异在 SCC 的 EGFP transgene 或内长的 Crygc 基因。变异的 SSC 在移植以后经历了精子发生进不肥沃的老鼠睾丸的生精的小管。圆 spermatids 被产生并且在进成熟卵母细胞的注射以后,支持了显示相应变异的显型的异质接合的后代的生产。而且,在 Crygc 的一个引起疾病的变化(在 SSC 先存在的 Crygc −/−) 能乐意地到加入的 CRISPR-Cas9-induced nonhomologous 结束(NHEJ ) 或指导相同的修理(HDR ) 被修理,导致没有是的离开目标修正的证据带改正的基因的 SSC 线由整个染色体的定序出现。用从这些线产生的圆 spermatids 的授精在 100% 的效率与改正的显型产生了后代。我们的结果表明有效基因由 CRISPR-Cas9 系统在老鼠 SSC 编辑,并且提供在 SSC 经由基因修正治好基因疾病的原则的证明。 | Yuxuan Wu Hai Zhou Xiaoying Fan Ying Zhang Man Zhang Yinghua Wang Zhenfei Xie Meizhu Bai Qi Yin Dan Liang Wei Tang Jiaoyang Liao Chikai Zhou Wujuan Liu Ping Zhu Hongshan Guo Hong Pan Chunlian Wu Huijuan Shi Ligang Wu Fuchou Tang Jinsong Li | 2015 | Cell Research2015，25，1： | 37 |
| 2 | Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1显示文摘Multisystem manifestations in myotonic dystrophy type 1(DM1)may be due to dosage reduction in multiple genes induced by aberrant expansion of CTG repeats in DMPK,including DMPK,its neighboring genes(SIX5 or DMWD)and downstream MBNLh However,direct evidence is lacking.Here,we develop a new strategy to generate mice carrying multigene heterozygous mutations to mimic dosage reduction in one step by injection of haploid embryonic stem cells with mutant Dmpk,Six5 and Mbnll into oocytes.The triple heterozygous mutant mice exhibit adult-onset DM1 phenotypes.With the additional mutation in Dmwd,the quadruple heterozygous mutant mice recapitulate many major manifestations in congenital DM1.Moreover,muscle stem cells in both models display reduced sternness,providing a unique model for screening small molecules for treatment of DM1.Our results suggest that the complex symptoms of DM1 result from the reduced dosage of multiple genes. | Qi Yin Hongye Wang Na Li Yifu Ding Zhenfei Xie Lifang Jin Yan Li Qiong Wang Xinyi Liu Liuqing Xu Qing Li Yongjian Ma Yanbo Cheng Kai Wang Cuiqing Zhong Qian Yu Wei Tang Wanjin Chen Wenjun Yang Fan Zhang Chen Ding Lan Bao Bin Zhou Ping Hu Jinsong Li | 2020 | Cell Research2020，30，2： | 7 |
| 3 | Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine显示文摘Mesenchymal stem cell(MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases,but its underlying mechanism has not been fully understood.Dead cells,including apoptotic cells have immunomodulatory properties.It has been repeatedly reported that the proportion of nonviable MSCs in a MSC therapeutic preparation varied from 5-50%in the ongoing clinical trials.It is conceivable that the nonviable cells in a MSC therapeutic preparation may play a role in the therapeutic effects of MSCs.We found that the MSC therapeutic preparation in the present study had about 5%dead MSCs(DMSCs),characterized by apoptotic cells.Namely,1×10^(6) MSCs in the preparation contained about 5×10^(4) DMSCs.We found that the treatment with even 5×10^(4) DMSCs alone had the equal therapeutic effects as with 1×10^(6) MSCs.This protective effect of the dead MSCs alone was confirmed in four mouse models,including concanavalin A(ConA)-and carbon tetrachloride(CCI4)-induced acute liver injury,LPS-induced lung injury and spinal cord injury.We also found that the infused MSCs died by apoptosis in vivo.Furthermore,the therapeutic effect was attributed to the elevated level of phosphatidylserine(PS)upon the injection of MSCs or DMSCs.The direct administration of PS liposomes(PSLs)mimic apoptotic cell fragments also exerted the protective effects as MSCs and DMSCs.The Mer tyrosine kinase(MerTK)deficiency or the knockout of chemokine receptor C-C motif chemokine receptor 2(CCR2)reversed these protective effects of MSCs or DMSCs.These results revealed that DMSCs alone in the therapeutic stem cell preparation or the apoptotic cells induced in vivo may exert the same immunomodulatory property as the'living MSCs preparation'through releasing PS,which was further recognized by MerTK and participated in modulating immune cells. | Xuemei He Weiqi Hong Jingyun Yang Hong Lei Tianqi Lu Cai He Zhenfei Bi Xiangyu Pan Yu Liu Lunzhi Dai Wei Wang Canhua Huang Hongxin Deng Xiawei Wei | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 6 |
| 4 | An Efficient Method for Estimating Capability Curve of Virtual Power Plant显示文摘To incorporate the operating constraints of a virtual power plant(VPP)in transmission-level operation and market clearing,the concept of the VPP capability curve(VPP-CC)is proposed which explicitly characterizes the allowable range of active and reactive power outputs of a VPP.A two-step projection-based calculation framework is proposed to approximate the VPP-CC by the convex hull of critical points on its perimeter.The output of the proposed algorithm is concise and can be easily incorporated in the existing system operation and market clearing.Case studies based on the IEEE 33 and 123 test feeders show the computational efficiency of the proposed method outperforms existing methods by 4~7 times.Additionally,many fewer inequalities are needed to depict the VPP-CC while achieving the comparative approximation accuracy compared to sampling-based methods,which will relieve the communication and computation burden. | Zhenfei Tan Haiwang Zhong Xuanyuan Wang Honghai Tang | 2022 | CSEE Journal of Power and Energy Systems2022，8，3： | 5 |
| 5 | Treatment of Helicobacter pylori-associated gastritis using traditional Chinese medicine显示文摘Helicobacter pylori is a pathogenic bacterium with strong pathogenicity, which can induce chronic gastritis and peptic ulcer in addition to causing gastric mucosal atrophy and intestinal metaplasia after longterm infection. It is even associated closely with the occurrence of gastric cancer and mucosa-associated lymphoid tissue lymphoma. Recently, the incidence of H. pylori-associated gastritis has increased rapidly worldwide, especially in China. The prevention and treatment of H. pylori infection has become an urgent issue to be resolved by the medical community. Traditional Chinese medicine and the combination of traditional Chinese medicine and Western medicine have recently shown unique advantages in the treatment of H. pylori–associated gastritis. The progress in this area is summarized in this review. | Mengjiao Hu Zhenfei Wang | 2018 | 国际感染病学(电子版)2018，7，1： | 4 |
| 6 | Digital Watermarking Algorithm Based on Wavelet Transform and Neural Network显示文摘An effective blind digital watermarking algorithm based on neural networks in the wavelet domain is presented. Firstly, the host image is decomposed through wavelet transform. The significant coefficients of wavelet are selected according to the human visual system (HVS) characteristics. Watermark bits are added to them. And then effectively cooperates neural networks to learn the characteristics of the embedded watermark related to them. Because of the learning and adaptive capabilities of neural networks, the trained neural networks almost exactly recover the watermark from the watermarked image. Experimental results and comparisons with other techniques prove the effectiveness of the new algorithm. | WANG Zhenfei ZHAI Guangqun WANG Nengchao | 2006 | Wuhan University Journal of Natural Sciences2006，11，6： | 4 |
| 7 | Systematic centroid error compensation for the simple Gaussian PSF in an electronic star map simulator显示文摘Simulated star maps serve as convenient inputs for the test of a star sensor, whose standardability mostly depends on the centroid precision of the simulated star image, so it is necessary to accomplish systematic error compensation for the simple Gaussian PSF(or SPSF, in which PSF denotes point spread function). Firstly, the error mechanism of the SPSF is described, the reason of centroid deviations of the simulated star images based on SPSF lies in the unreasonable sampling positions(the centers of the covered pixels) of the Gaussian probability density function. Then in reference to the IPSF simulated star image spots regarded as ideal ones, and by means of normalization and numerical fitting, the pixel center offset function expressions are got, so the systematic centroid error compensation can be executed simply by substituting the pixel central position with the offset position in the SPSF. Finally, the centroid precision tests are conducted for the three big error cases of Gaussian radius r = 0.5, 0.6, 0.671 pixel, and the centroid accuracy with the compensated SPSF(when r = 0.5) is improved to 2.83 times that of the primitive SPSF, reaching a 0.008 pixel error, an equivalent level of the IPSF. Besides its simplicity, the compensated SPSF further increases both the shape similarity and the centroid precision of simulated star images, which helps to improve the image quality and the standardability of the outputs of an electronic star map simulator(ESS). | Wang Haiyong Wang Yonghai Li Zhifeng Song Zhenfei | 2014 | Chinese Journal of Aeronautics2014，27，4： | 3 |
| 8 | Microstructure and Mechanical Behavior of FeNiCoCr and FeNiCoCrMn High-Entropy Alloys Fabricated by Powder Metallurgy显示文摘The present work reports a systematic investigation on phase evolution,microstructure and microstructure-property relationship of two typical face-centered cubic(FCC)structured high-entropy alloys(HEAs),FeNiCoCr and FeNiCoCrMn,prepared via mechanical alloying(MA)followed by spark plasma sintering(SPS).Following 50 h of MA,the two HEAs consisted of a mixture of FCC and body-centered cubic phases.Following SPS,the bulk FeNiCoCr alloy showed a primary FCC phase with a small amount of Cr_(23)C_(6) and Cr_(2)O_(3) contaminants,while the bulk FeNiCoCrMn alloy was composed of a primary FCC phase with some(Cr,Mn)23C6 and MnCr_(2)O_(4) contaminants.The average grain size of the primary FCC phase in the bulk FeNiCoCr alloy was~416 nm,while that of the primary FCC phase in the bulk FeNiCoCrMn alloy was~547 nm.The yield strength,compressive strength and strain-to-failure of the bulk FeNiCoCr alloy are 1525 MPa,1987 MPa and 24.4%,respectively,whereas those of the bulk FeNiCoCrMn alloy are 1329 MPa,1761 MPa and 21.9%,respectively.It suggests that the bulk FeNiCoCrMn exhibited lower strength and plasticity in comparison with the bulk FeNiCoCr alloy.Clearly,the smaller grain size of the primary FCC phase in the FeNiCoCr alloy is mainly responsible for the better mechanical performance. | Chenliang Chu Weiping Chen Zhen Chen Zhenfei Jiang Hao Wang Zhiqiang Fu | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，4： | 3 |
| 9 | The mechanism of HBx protein to promote the initiation and progression of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is the sixth most common malignancy worldwide and the third most common cause of death from cancer, after lung and stomach cancer. Hepatitis B virus(HBV) infection is closely related to HCC and is a major cause of HCC. HBV is a lysogenic virus of the hepadnavirus family. Its genome presents a slack, ring-like, double-chain structure, containing four open reading frames. The X region encodes the product HBV X protein(HBx), which is a multifunctional regulatory protein that plays an important role in intracellular signal transduction, viral genome replication and transcription, cell proliferation and apoptosis, cell cycle progression, protein degradation, and genetic stability of hepatocytes. This article summarizes the recent research on the mechanism of promotion of initiation and progression of HCC by HBx protein. | Muyao Zhang Xing Wei Zhenfei Wang | 2018 | 国际感染病学(电子版)2018，7，1： | 2 |
| 10 | Cloning and characterization of a novel CBL-interacting protein kinase from maize显示文摘 | Jinfeng Zhao Zhenfei Sun Jun Zheng Xiying Guo Zhigang Dong Junling Huai Mingyue Gou Junguang He Yongsheng Jin Jianhua Wang Guoying Wang | 2009 | Plant Molecular Biology2009，，6： | 2 |
| 11 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 12 | Organophosphate esters cause thyroid dysfunction via multiple signaling pathways in zebrafish brain显示文摘Organophosphate esters(OPEs)are widespread in various environmental media,and can disrupt thyroid endocrine signaling pathways.Mechanisms by which OPEs disrupt thyroid hormone(TH)signal transduction are not fully understood.Here,we present in vivo-in vitro-in silico evidence establishing OPEs as environmental THs competitively entering the brain to inhibit growth of zebrafish via multiple signaling pathways.OPEs can bind to transthyretin(TTR)and thyroxine-binding globulin,thereby affecting the transport of TH in the blood,and to the brain by TTR through the blood-brain barrier.When GH3 cells were exposed to OPEs,cell proliferation was significantly inhibited given that OPEs are competitive inhibitors of TH.Cresyl diphenyl phosphate was shown to be an effective antagonist of TH.Chronic exposure to OPEs significantly inhibited the growth of zebrafish by interfering with thyroperoxidase and thyroglobulin to inhibit TH synthesis.Based on comparisons of modulations of gene expression with the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases,signaling pathways related to thyroid endocrine functions,such as receptor-ligand binding and regulation of hormone levels,were identified as being affected by exposure to OPEs.Effects were also associated with the biosynthesis and metabolism of lipids,and neuroactive ligand-receptor interactions.These findings provide a comprehensive understanding of the mechanisms by which OPEs disrupt thyroid pathways in zebrafish. | Zhenfei Yan Chenglian Feng Xiaowei Jin Fangkun Wang Cong Liu Na Li Yu Qiao Yingchen Bai Fengchang Wu John P.Giesy | 2022 | Environmental Science and Ecotechnology2022，，4： | 2 |
| 13 | The properties of cementitions materials superlasticized with two superplasticizers based on aminosulfonate-phenol-formalde- hyde显示文摘 | Meishan Pei Zhenfei Wang Wenwei Li | 2008 | Construction and Building Materials2008，22，： | 1 |
| 14 | A new 5G radio evolution towards 5G-Advanced显示文摘The evolution of the fifth-generation(5G)new radio(NR)has progressed swiftly since the third generation partnership project(3GPP)standardized the first NR version(Release 15)in mid-2018.Nowadays,the world’s leading carriers are competing to provide various commercial services over 5G networks.Looking ahead to 2025 and beyond,it is expected that over 6.5 million 5G base stations will be installed to offer services to over 58%of the world’s population via over 100 billion 5G connections.Following the rapid development of 5G,an increasing number of commercialization use cases will drive the 5G network to continuously improve performance and expand capabilities.Hence,it is the right time to consider a welldefined framework and standardization for 5G NR evolution(5G-Advanced)to support commercialization between 2025 and 2030.First,this study addresses the key driving forces,requirements,usage scenarios,and capabilities of 5G-Advanced;then,it highlights the main technological challenges and introduces the top 10 promising technological directions in detail.Finally,other fascinating technological directions in5G-Advanced are shortly mentioned. | Jiyong PANG Shaobo WANG Zhenfei TANG Yanmin QIN Xiaofeng TAO Xiaohu YOU Jinkang ZHU | 2022 | Science China(Information Sciences)2022，65，9： | 1 |
| 15 | A simple eolori- metric method for determination of hydrogen peroxide in plant tis- sues显示文摘 | ZHOU Biyan WANG Jihua GUO Zhenfei | 2006 | Plant Growth Regulation2006，49，： | 1 |
| 16 | A simple colorimetric method for determination of hydrogen peroxide in plant tissues显示文摘 | ZHOU Biyan WANG Jihua GUO Zhenfei | 2006 | Plant Growth Regulation2006，49，： | 1 |
| 17 | A New Method to Construct Education Knowledge Graph显示文摘Learning from the Internet is becoming more and more convenient and attracting more and more people. How to obtain knowledge from massive data and construct high quality knowledge graph has become a research hot topic. This paper proposes a new method of knowledge graph construction based on crowd-sourcing. Firstly, learners build the subgraphs to acquire knowledge through the crowd-sourcing task; secondly, we put forward the fusion strategy of knowledge subgraph, in which knowledge graph is converted into the adjacency matrix, and the weight of the knowledge relation is calculated by matrix operations, thus knowledge graph is constructed. Finally, experiments conducted on an open platform show that the accuracy and integrity of proposed method of constructing knowledge graph are higher and our new method exists potential value for online learning and self-regulated learning. | Zhiyun Zheng Jianping Wu Zhenfei Wang Zhongyong Wang Liming Wang Dun Li | 2018 | 计算机教育2018，，12： | 1 |
| 18 | Genome-wide profiling of histone H3 lysine 27 trimethylation and its modification in response to chilling stress in grapevine leaves显示文摘Histone H3 lysine 27 trimethylation(H3K27me3) is a histone modification associated with transcriptional repression. However, insights into the genome-wide pattern of H3K27me3 in grapevines are limited. Here, anti-H3K27 chromatin immunoprecipitation(ChIP), high-throughput sequencing, and transcriptome analysis were performed using leaves of Vitis amurensis. The leaves were treated at 4°C for 2 h and 24 h and used to investigate changes in H3K27me3 under chilling treatment. The results show that H3K27me3 is well-distributed both in gene regions(-50%) and in the intergenic region(-50%) in the grapevine genome(Vitis vinifera ‘Pinot Noir PN40024'). H3K27me3 was found to be localized in8 368 annotated gene regions in all detected samples(leaves at normal temperature and under chilling treatments) and mainly enriched in gene bodies with the adjacent promoter and downstream areas. The short-term chilling treatments(4°C for 2 h) induced 2 793 gains and 305losses in H3K27me3 modification. Subsequently, 97.3% of the alterations were restored to original levels after 24 h treatment. The ChIP-qPCR for five differential peaks showed similar results to the data for ChIP-seq, indicating that the chilling-induced H3K27me3 modification is reliable.Integrative analysis of transcriptome and ChIP-seq results showed that the expression of H3K27me3 target genes was significantly lower than those of non-target genes, indicating transcriptional repression of H3K27me3 in grapevine leaves. Furthermore, histone methylation alterations were detected in 82 genes and were related to either repression or activation of their expression during chilling stress. The findings provide the genome-wide H3K27me3 patterns in grapevines and shed light on uncovering its regulation in chilling stress responses. | Zhenfei Zhu Qingyun Li Duncan Kiragu Gichuki Yujun Hou Yuanshuang Liu Huimin Zhou Chen Xu Linchuan Fang Linzhong Gong Beibei Zheng Wei Duan Peige Fan Qingfeng Wang Haiping Xin | 2023 | Horticultural Plant Journal2023，9，3： | 1 |
| 19 | Incidence,genomic diversity,and evolution of strawberry mottle virus in China显示文摘Strawberry mottle virus(SMoV)is one of the most common viruses infecting strawberries,causing losses to fruit yield and quality.In this study,165 strawberry leaf samples were collected from six provinces of China,46 of which tested positive for SMoV.The complete genome sequences of 11 SMoV isolates were obtained from Liaoning(DGHY3,DGHY16-2,DGHY17,DGHY20-2,DGHY21,DGHY26-2),Shandong(SDHY1,SDHY5,SDHY31-2,SDHY33-2),and Beijing(BJMX7).The RNA1 and RNA2 nucleotide identities between the 11 Chinese isolates were 95.4-99.3%and 96.3-99.6%,respectively,and they shared 78.4-96.6%and 84.8-93.5%identities with the available SMoV isolates in GenBank.Recombination analysis revealed that Chinese isolate SDHY33-2 and Canadian isolates Ontario and Simcoe were recombinants,and recombination events frequently occurred in the 3’UTR of SMoV.Phylogenetic analysis showed that in an RNA1 tree,most Chinese isolates clustered into the same group while isolate DGHY17 clustered into another group together with Czech isolate C and three Canadian isolates.In an RNA2 tree,all Chinese isolates clustered into a single group.The phylogenetic analysis based on nucleotide sequences was consistent with the results based on coat protein(CP)and RNA-dependent RNA polymerase(RdRp).Further evolutionary analysis indicated that negative selection drives SMoV evolution,and gene flow plays a major role in genetic differentiation.Additionally,reassortment and recombination also influence the evolution of SMoV.To our knowledge,this is the first report of the complete genome of SMoV isolates from China and a detailed analysis of the SMoV population structure. | LINGJIAO FAN CHENGYONG HE MENGMENG WU DEHANG GAO ZHENFEI DONG SHENGFAN HOU ZEKUN FENG HONGQING WANG | 2021 | BIOCELL2021，45，4： | 1 |
| 20 | Radix Glehniae extract inhibits the migration and invasion abilities of lung cancer cells显示文摘Objective: To investigate the effect of Radix Glehniae on the migration and invasion abilities of lung cancer cells, and to explore the underlying mechanism. Method: Normal human bronchial cell line 16 HBE and lung cancer cell line SK-MES-1 were cultured in vitro. Radix Glehniae extract was prepared to treat the two kinds of cells. The proliferation ability of 16 HBE cells was determined by CCK-8 assay. The migration and invasion abilities of SK-MES-1 cells were determined by Transwell and Matrigel assays, respectively. The expression of TIMP2 m RNA in SK-MES-1 cells was detected by fluorescence quantitative PCR(q-PCR). The secretion level of TIMP2 protein by SK-MES-1 cells was measured by ELISA experiment. Results: Radix Glehniae extract caused no toxic effects on 16 HBE cells at the concentrations of 1 mg/ml to 15 mg/ml. Radix Glehniae extract(from 5 mg/ml to 15 mg/ml) significantly inhibited SK-MES-1 cell migration and invasion abilities, as well as upregulated TIMP2 m RNA expression and enhanced TIMP2 secretion by SK-MES-1 cells. Conclusion: Radix Glehniae can inhibit the migration and invasion behaviors of lung cancer cells by upregulating TIMP2 expression and secretion. | Zhenfei Wang Jingquan Li | 2017 | 国际感染病学(电子版)2017，6，2： | 1 |
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