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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | 外刊拾贝显示文摘1.根据2018年美国糖尿病学会标准诊断中国糖尿病患病率:全国横断面研究目的:评估糖尿病患病率及其危险因素。设计:基于人群的横断面研究。背景:2015-2017年中国大陆31省份全国横断面数据。调查对象:75880名18周岁及以上代表中国大陆人口的成年人样本。主要观察指标:根据2018年美国糖尿病学会和世界卫生组织标准诊断中国成人不同性别、区域和种族的糖尿病患病率。通过问卷的方式记录调查对象的社会人口学信息、生活方式和疾病史。 | 单忠艳 Li Y Teng D Shi X Ba J 王看然 李启富 Wang K Hu J Yang J | 2020 | 国际内分泌代谢杂志2020，40，5： | 42 |
| 3 | Status monitoring and health assessment of Luhuitou fringing reef of Sanya, Hainan, China显示文摘The monitoring survey and health assessment for benthic community were carried out in Luhuitou fringing reef of Sanya, Hainan, China in 2002. Monitoring survey included manta tow, line intercept transect, video transect and digital photograph. The mean live coral cover was 23.40%. Comparison of used monitoring methods showed that video transect can replace line intercept transect, and 50 m transect is better than 20 m transect in uneven coral region. Survey data and comparison with previous research work showed that Luhuitou fringing reef has been damaged severely and has a general declining trend with live coral cover from about 85% in the 1960s down to 20% in 2004, but it still has quite high biodiversity and therefore has special protection value. Main factors of Luhuitou fringing reef declining were human activities including reef rock digging and curios collecting, destructive fishing, sediment and pollutant from coastal land, and recent marine aquaculture. Only strengthening integrated management can reach improvement and restoration of Luhuitou declining coral reef ecosystem. | ZHANG Qiaomin SHI Qi CHEN Gang FONG T C W WONG D C C HUANG Hui WANG Hankui ZHAO Meixia | 2006 | Chinese Science Bulletin2006，51，B12： | 15 |
| 4 | Immunopathogenesis of chronic hepatitis B显示文摘Chronic hepatitis B(CHB) is a widespread infectious disease with unfavorable outcomes and life-threatening consequences for patients, in spite of modern vaccination and antiviral treatment modalities. Cutting-edge experimental approaches have demonstrated key pathways that involve cross-talk between viral particles and host immune cells. All events, including penetration of hepatitis B virus(HBV) particles into host cells, establishing persistence, and chronization of CHB infection, and possibility of complete elimination of HBV particles are controlled by the immune system. Researchers have paid special attention to the replication capacity of HBV in host cells, which is associated with cellular changes that reflect presentation of viral antigens and variability of HBV antigen features. In addition, specific HBV proteins have an immune-modulating ability to initiate molecular mechanisms that 'avoid' control by the immune system. The relationship between immunological shifts and chronic infection stages has been intensively studied since it was recognized that the immune system is a direct participant in the recurrent(cyclic) nature of CHB. Understanding the wide diversity of molecular pathways and the crosstalk between innate and adaptive immune system components will provide fresh insight into CHB immune pathogenesis and the possibilities of developing new treatment strategies for this disease. | Irina P Balmasova Nikolay D Yushchuk Ospan A Mynbaev Nageswara R Alla Elena S Malova Zhongjie Shi Chang-Lu Gao | 2014 | World Journal of Gastroenterology2014，20，39： | 15 |
| 5 | 中国社区健康素养与高血压治疗之间的关系:回顾性队列研究显示文摘健康素养较低与临床预后差相关。健康素养与血压之间的关系研究结果不一致。该研究调查了健康素养的决定因素和健康素养与高血压管理之间的潜在关系。方法:对360例高血压患者进行回顾性队列研究。基于标准方案进行测量、体检和实验室检查。 | 刘莉 叶鹏 Shi D Li J Wang Y Wang S Liu K Shi R Zhang Q Chen X | 2017 | 中华高血压杂志2017，25，5： | 14 |
| 6 | Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and Oseltamivir by suppressing the expression of Carboxylesterases HCE1 and HCE2显示文摘 | Yang,j shi,D Yang,DF Song,XL Yan,BF | 2007 | 南京医科大学学报(自然科学版)2007，27，11： | 9 |
| 7 | Structure and Property of Bamboo Fiber显示文摘The chemical composition, fiber characteristics, crystalline structure, mechanical properties and thermal behavior of the five species of bamboo (Phyllostachys edulis cv.Pachyloe, Bambusa tootisk, Arundinaia amabilis, B.vulgaris cv. Vittata, and Dendrocalamus affinis) were studied with IR, X-ray, DSC and chemical analyses. The results indicated that the benzene-ethanol extractive content of bamboo was higher than that of wood, the content of lignin and the content of pentosan were 19.1% - 25.3% and 14.9% - 22.6%, respectively. Except for Ph. edulis cv. Pachyloe, the cellulose content in the other 4 species was over 50%. The average length of fiber of D. affinis was the longest (1.861 mm). The length/ width ratio of bamboo fiber was also higher than that of wood, and it was the highest for B.tootisk, which reached 142. The results of IR and X-ray confirmed that crystalline structure of bamboo fibers was cellulose, and A. amabilis had the highest crystallinity index. The differential thermal analysis (DSC) can be one of the methods to identify various fiber materials. After steam explosive pretreatment, cellulose content of D. affinis had increased from 50.5% to 69.2%, the crystallinity index had increased and the breaking tenacity of bamboo fibers was suitable for producing textile products, indicating that steam explosion is an useful pretreatment for bamboo fibers made into composite materials and textiles. | JIANG Jianxin1 YANG Zhongkai2 ZHU Liwei1 SHI Limin2 YAN Lijie1 1. College of Materials Science and Technology, Beijing Forestry University, Beijing100083, P. R. China 2 .Beijing Municipal Key Laboratory of Clothing Materials R & D and Assessment, Beijing Institute of Clothing Technology, Beijing 100029, P. R. China. | 2008 | Chinese Forestry Science and Technology2008，7，2： | 8 |
| 8 | Identification of pathologic features associated with “ulcerative colitis-like” Crohn's disease显示文摘AIM: To identify pathologic features associated with this 'ulcerative colitis(UC)-like' subgroup of Crohn's disease(CD).METHODS: Seventeen subjects diagnosed as having UC who underwent proctocolectomy(RPC) from 2003-2007 and subsequently developed CD of the ileal pouch were identified. UC was diagnosed based on preoperative clinical, endoscopic, and pathologic studies. Eighteen patients who underwent RPC for UC within the same time period without subsequently developing CD were randomly selected and used as controls. Pathology reports and histological slides were reviewed for a wide range of gross and microscopic pathological features, as well as extent of disease. The demographics, gross description and histopathology of the resection specimens were reviewed and compared between the two groups. RESULTS: Patients with 'UC-like' CD were on average 13 years younger than those with 'true' UC(P < 0.01). More severe disease in the proximal involved region and active ileitis with/without architectural distortion were observed in 6 of 17(35%) and 7 of 17(41%) 'UC-like' CD cases, respectively, but in none of the 'true' UC cases(P < 0.05). Active appendicitis occurred in 8 of 16(50%) 'UC-like' CD cases but in only two(11%) 'true' UC cases(P < 0.05). Conspicuous lamina propria neutrophils were more specific for 'UClike' CD(76% vs 22%, P < 0.05). In addition, prominent lymphoid aggregates tended to be more common in 'UC-like' CD(P = 0.07). The 'true' UC group contained a greater number of cases with severe activity(78% vs 47%). Therefore, the features more commonly seen in 'UC-like' CD were not due to a more severe disease process. Crohn's granulomas and transmural inflammation in non-ulcerated areas were absent in both groups.CONCLUSION: More severe disease in the proximal involved region, terminal ileum involvement, active appendicitis, and prominent lamina propria neutrophils may be morphological factors associated with 'UC-like' CD. | Samuel D James Paul E Wise Tania Zuluaga-Toro David A Schwartz M Kay Washington Chanjuan Shi | 2014 | World Journal of Gastroenterology2014，20，36： | 4 |
| 9 | Agent-oriented Aid-modeling for the Distributed Activity Network | DENG Gui\|shi\+1,\ LI Wen\|lei\+1,\ O. Moeschlin\+2 1.Institute of Systems Engineering, Dalian University of Technology Dalian 116024, China 2.Department of Mathematics, Fern University in Hagen, D 58084 Germany | 2000 | Systems Science and Systems Engineering2000，10，1： | 4 |
| 10 | The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial显示文摘 | Scott D Solomon Michael Zile Burkert Pieske Adriaan Voors Amil Shah Elisabeth Kraigher-Krainer Victor Shi Toni Bransford Madoka Takeuchi Jianjian Gong Martin Lefkowitz Milton Packer John JV McMurray | 2012 | 2012 (9851)2012，，9851： | 3 |
| 11 | Adjunctive MSCs enhance myelin formation by xenogenic oligodendrocyte precursors transplanted in the retina显示文摘 | Aileen Arriola Mary E Kiel Yufang Shi Randall D McKinnon | 2010 | Cell Research2010，20，6： | 3 |
| 12 | Indoor mite allergen levels, specific IgE prevalence and IgE cross-inhibition pattern among asthmatic children in Haikou, southern China显示文摘 | ZHENG Yi-wu CHEN Shi LAI Xu-xin Birgitte Gjesing ZHONG Nan-shan Michael D Spangfort | 2012 | Chinese Medical Journal2012，，17： | 3 |
| 13 | The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial显示文摘 | Scott D Solomon Michael Zile Burkert Pieske Adriaan Voors Amil Shah Elisabeth Kraigher-Krainer Victor Shi Toni Bransford Madoka Takeuchi Jianjian Gong Martin Lefkowitz Milton Packer John JV McMurray | 2012 | The Lancet2012，，9851： | 2 |
| 14 | Engineering of dendritic dopant-free hole transport molecules:enabling ultrahigh fill factor in perovskite solar cells with optimized dendron construction显示文摘Developing dopant-free hole-transporting materials(HTMs)for high-performance perovskite solar cells(PVSCs)has been a very active research topic in recent years since HTMs play a critical role in optimizing interfacial charge carrier kinetics and in turn determining device performance.Here,a novel dendritic engineering strategy is first utilized to design HTMs with a D-A type molecular framework,and diphenylamine and/or carbazole is selected as the building block for constructing dendrons.All HTMs show good thermal stability and excellent film morphology,and the key optoelectronic properties could be fine-tuned by varying the dendron structure.Among them,MPA-Cz-BTI and MCz-Cz-BTI exhibit an improved interfacial contact with the perovskite active layer,and non-radiative recombination loss and charge transport loss can be effectively suppressed.Consequently,high power conversion efficiencies(PCEs)of 20.8%and 21.35%are achieved for MPA-Cz-BTI and MCz-Cz-BTI based devices,respectively,accompanied by excellent long-term storage stability.More encouragingly,ultrahigh fill factors of 85.2%and 83.5%are recorded for both devices,which are among the highest values reported to date.This work demonstrates the great potential of dendritic materials as a new type of dopant-free HTMs for high-performance PVSCs with excellent FF. | Wei Chen Yang Wang Bin Liu Yajun Gao Ziang Wu Yongqiang Shi Yumin Tang Kun Yang Yujie Zhang Weipeng Sun Xiyuan Feng Frédéric Laquai Han Young Woo Aleksandra B.Djurisic Xugang Guo Zhubing He | 2021 | Science China Chemistry2021，64，1： | 2 |
| 15 | Carbon fiber-rein- forced concrete for traffic monitoring and weighing in motion显示文摘 | Zeng-Qiang Shi Chung D D L | 1999 | Cement and Concrete Research1999，29，： | 1 |
| 16 | Development of a chimacric receptor approach to study signaling by tumour necrosis factor family members 显示文摘 | Xu D Shi Z McDonnald J | 2004 | Biochem J2004，383，4： | 1 |
| 17 | ATP-induced changes in energy status and membrane integrity of harvested litchi fruit and its relation to pathogen resistance 显示文摘 | YI C QU H X JIANG Y M SHI J DUAN X W JOYCE D C LI Y B | 2008 | Journal of Phytopathology2008，156，： | 1 |
| 18 | Microcalcifi cation detection using fuzzy logic and scale space ap proaches显示文摘 | Cheng H D Wang Jingli Shi Xiangjun | 2004 | Pattern Recognition2004，，37： | 1 |
| 19 | Effect of Nanoparticles on the Performance of Thermally Conductive Epoxy Adhesives显示文摘 | Fu J F Shi L Y Zhang D S | 2010 | Polymer Engineering and Science2010，50，9： | 1 |
| 20 | Mammalian N-acetylglutamate synthase显示文摘 | Morizono H Caldovic L Shi D | 2004 | Mol Genet Metab2004，811，： | 1 |
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