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| 1 | Application of Next-generation Sequencing Technology in Forensic Science显示文摘Next-generation sequencing(NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multiple loci of forensic interest in different genetic contexts, such as autosomes, mitochondrial and sex chromosomes. Furthermore, NGS technology can also have potential applications in many other aspects of research. These include DNA database construction, ancestry and phenotypic inference,monozygotic twin studies, body fluid and species identification, and forensic animal, plant and microbiological analyses. Here we review the application of NGS technology in the field of forensic science with the aim of providing a reference for future forensics studies and practice. | Yaran Yang Bingbing Xie Jiangwei Yan | 2014 | Genomics, Proteomics & Bioinformatics2014，12，5： | 13 |
| 2 | On-chip erbium-doped lithium niobate microcavity laser显示文摘The commercialization of lithium niobate on insulator(LNOI) wafer has resulted in significant on-chip photonic integration application owing to its remarkable photonic,acousto-optic,electro-optic,and piezoelectric nature.In recent years,a variety of high-performance on-chip LNOI-based photonic devices have been realized.In this study,we developed a 1-mol% erbium-doped lithium niobate crystal and its LNOI on a silicon substrate and fabricated an erbium-doped LNOI microdisk with high quality factor(~1.05×105).C-band laser emission at ~1530 and ~1560 nm(linewidth 0.12 nm) from the high-Q erbium-doped LNOI microdisk was demonstrated with 974-and 1460-nm pumping,with the latter having better thermal stability.This microlaser would play an important role in the photonic integrated circuits of the lithium niobate platform. | YiAn Liu XiongShuo Yan JiangWei Wu Bing Zhu YuPing Chen XianFeng Chen | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，3： | 7 |
| 3 | Characterization of miRNomes in Acute and Chronic Myeloid Leukemia Cell Lines显示文摘Myeloid leukemias are highly diverse diseases and have been shown to be associated with microRNA(miRNA) expression aberrations. The present study involved an in-depth miRNome analysis of two human acute myeloid leukemia(AML) cell lines, HL-60 and THP-1, and one human chronic myeloid leukemia(CML) cell line, K562, via massively parallel signature sequencing. mRNA expression profiles of these cell lines that were established previously in our lab facilitated an integrative analysis of miRNA and mRNA expression patterns. miRNA expression profiling followed by differential expression analysis and target prediction suggested numerous miRNA signatures in AML and CML cell lines. Some miRNAs may act as either tumor suppressors or oncomiRs in AML and CML by targeting key genes in AML and CML pathways. Expression patterns of cell type-specific miRNAs could partially reflect the characteristics of K562, HL-60 and THP-1 cell lines, such as actin filament-based processes, responsiveness to stimulus and phagocytic activity. miRNAs may also regulate myeloid differentiation, since they usually suppress differentiation regulators. Our study provides a resource to further investigate the employment of miRNAs in human leukemia subtyping, leukemogenesis and myeloid development. In addition, the distinctive miRNA signatures may be potential candidates for the clinical diagnosis, prognosis and treatment of myeloid leukemias. | Qian Xiong Yadong Yang Hai Wang Jie Li Shaobin Wang Yanming Li Yaran Yang Kan Cai Xiuyan Ruan Jiangwei Yan Songnian Hu Xiangdong Fang | 2014 | Genomics, Proteomics & Bioinformatics2014，12，2： | 6 |
| 4 | The spatial variation of soil bacterial community assembly processes affects the accuracy of source tracking in ten major Chinese cities显示文摘Urban soils harbor billions of bacterial cells and millions of species.However,the distribution patterns and assembly processes of bacterial communities remain largely uncharacterized in urban soils.It is also unknown if we can use the bacteria to track soil sources to certain cities and districts.Here,Illumina MiSeq sequencing was used to survey soil bacterial communities from 529 random plots spanning 61 districts and 10 major cities in China.Over a 3,000 km range,community similarity declined with increasing geographic distance(Mantel r=0.62),and community composition was clustered by city(R^(2)=0.50).Within cities(<100 km),the aforementioned biogeographic patterns were weakened.Process analysis showed that homogenizing dispersal and dispersal limitation dominated soil bacterial assembly at small and large spatial scales,respectively.Accordingly,the probabilities of accurately tracking random soil sources to certain cities and districts were 90.0% and 66.7%,respectively.When the tested samples originated from cities that were more than 1,265 km apart,the soil sources could be identified with nearly 100% accuracy.Overall,this study demonstrates the strong distance-decay relationship and the clear geographic zoning of urban soil bacterial communities among cities.The varied importance of different community assembly processes at multiple spatial scales strongly affects the accuracy of microbial source tracking. | Teng Yang Yu Shi Jun Zhu Chang Zhao Jianmei Wang Zhiyong Liu Xiao Fu Xu Liu Jiangwei Yan Meiqing Yuan Haiyan Chu | 2021 | Science China(Life Sciences)2021，64，9： | 4 |
| 5 | Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data ReleaseⅠ显示文摘Observing and timing a group of millisecond pulsars with high rotational stability enables the direct detection of gravitational waves(GWs).The GW signals can be identified from the spatial correlations encoded in the times-of-arrival of widely spaced pulsar-pairs.The Chinese Pulsar Timing Array(CPTA)is a collaboration aiming at the direct GW detection with observations carried out using Chinese radio telescopes.This short article serves as a“table of contents”for a forthcoming series of papers related to the CPTA Data Release 1(CPTA DR1)which uses observations from the Five-hundred-meter Aperture Spherical radio Telescope.Here,after summarizing the time span and accuracy of CPTA DR1,we report the key results of our statistical inference finding a correlated signal with amplitude logA_(c)=-14.4_(-2.8)^(+1.0)for spectral index in the range ofα∈[-1.8,1.5]assuming a GW background(GWB)induced quadrupolar correlation.The search for the Hellings–Downs(HD)correlation curve is also presented,where some evidence for the HD correlation has been found that a 4.6σstatistical significance is achieved using the discrete frequency method around the frequency of 14 n Hz.We expect that the future International Pulsar Timing Array data analysis and the next CPTA data release will be more sensitive to the n Hz GWB,which could verify the current results. | Heng Xu Siyuan Chen Yanjun Guo Jinchen Jiang Bojun Wang Jiangwei Xu Zihan Xue RNicolas Caballero Jianping Yuan Yonghua Xu Jingbo Wang Longfei Hao Jingtao Luo Kejia Lee Jinlin Han Peng Jiang Zhiqiang Shen Min Wang Na Wang Renxin Xu Xiangping Wu Richard Manchester Lei Qian Xin Guan Menglin Huang Chun Sun Yan Zhu | 2023 | Research in Astronomy and Astrophysics2023，23，7： | 3 |
| 6 | 6 GHz hyperfast rotation of an optically levitated nanoparticle in vacuum显示文摘We report an experimental observation of a record-breaking ultrahigh rotation frequency about 6 GHz in an optically levitated nanoparticle system. We optically trap a nanoparticle in the gravity direction with a high numerical aperture (NA) objective lens,which shows significant advantages in compensating the influences of the scattering force and the photophoretic force on the trap,especially at intermediate pressure (about100 Pa). This allows us to trap a nanoparticle from atmospheric to low pressure (10^(-3)Pa) without using feedback cooling. We measure a highest rotation frequency about 4.3 GHz of the trapped nanoparticle without feedback cooling and a 6 GHz rotation with feedback cooling,which is the fastest mechanical rotation ever reported to date.Our work provides useful guides for efficiently observing hyperfast rotation in the optical levitation system and may find various applications such as in ultra-sensitive torque detection,probing vacuum friction,and testing unconventional decoherence theories. | YUANBIN JIN JIANGWEI YAN SHAH JEE RAHMAN JIE LI XUDONG YU JING ZHANG | 2021 | Photonics Research2021，9，7： | 3 |
| 7 | Genetic polymorphisms for 17 Y-chromosomal STRs haplotypes in Chinese Hui population 显示文摘 | Guo Hua Yan Jiangwei Jiao Zhangping | 2008 | Legal Medicine2008，10，： | 1 |
| 8 | Genetic polymorphisms of 17 Y-STRs haplotypes in Chinese Han population residing in Shandong province of China 显示文摘 | Yan Jiangwei Tang Hui Liu Yacheng | 2007 | Legal Medicine2007，9，： | 1 |
| 9 | Population genetic analysis of 15 STR loci of Chinese Tu ethnic minority group 显示文摘 | BOFENG ZHU JIANGWEI YAN CHUNMEI SHEN | 2008 | Forensic Science International2008，174，23： | 1 |
| 10 | The structure and magnetic properties of Mn-Zn ferrite thin films fabricated by alternately sputtering显示文摘 | Liu Yan Cao Jiangwei Yang Zheng | 2006 | Mater Sci Eng B2006，127，： | 1 |
| 11 | Chip-scale spontaneous quasi-phase matched second harmonic generation in a micro-racetrack resonator显示文摘In this paper,we demonstrate efficient spontaneous quasi-phase matched(SQPM)second harmonic generation(SHG)in a microracetrack resonator on X-cut thin film lithium niobate.Our approach does not involve poling,but exploits the anisotropy of the crystals to allow the phase-matching condition to be fulfilled spontaneously as the TE-polarized light circulates in a specifically designed racetrack resonator.In experiment,normalized on-chip conversion efficiencies of 1.01×10-4/W and 0.43×10-4/W are achieved by 37th-order and 111th-order SQPM,respectively.The configurable SQPM will benefit the application of nonlinear frequency conversion and quantum source generation in chip-scale integrated photonics compatible with standard CMOS fabrication processes. | Tingge Yuan Jiangwei Wu Yi'an Liu Xiongshuo Yan Haowei Jiang Hao Li Zhaokang Liang Qiang Lin Yuping Chen Xianfeng Chen | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 1 |
| 12 | The torque measurement method and characteristics analysis based on magnetoelasticity显示文摘 | Jiangwei Chu Bingyuan Han Yan Wang | 2011 | Proceedings of the IEEE Instrumentation and Measurement Technology2011，4，： | 1 |
| 13 | The structure and magnetic properties of Mn-Zn ferrite thin films fabricated by alternately sputtering显示文摘 | Yan Liu Jiangwei Cao Zheng Yang | 2006 | Materials Science and Engineering B2006，127，： | 1 |
| 14 | Strain-Assisted Single Pt Sites on High-Curvature MoS_(2)Surface for Ultrasensitive H_(2)S Sensing显示文摘Engineering the local three-dimensional structure of metal sites has an important effect of maximizing the activity and selectivity of single-atom site catalysts.Here,we engineered a strain-assisted single Pt sites structure on a highly curved MoS_(2)surface to enhance its H_(2)S sensor property.By introducing N-methyl-2-pyrrolidone(NMP)as guiding molecules,a multilayer MoS_(2)structure with bending base planes was achieved.This bending behavior could inject not only uniform in-plane strain into the original inert MoS_(2)basal plane but also introduce sufficient accessible sites to anchor Pt monomers.Further experimental and theoretical results showed that the highcurvature MoS_(2)surface endowed 0.8%stretch strain onto the low-coordinated single Pt sites with a unique“tip”effect,which led to more accumulation of electrons around the Pt species,thereby accelerating the electric transfer process between H_(2)S and supports.The final catalyst delivered pronouncedly enhanced H_(2)S sensing response and response speed at room temperature.Our proposed strain-assisted strategy might create a new path to design highly active single-atom site catalysts for gas sensors. | Zhenggang Xue Chun Wang Yujing Tong Muyu Yan Jiangwei Zhang Xiao Han Xun Hong Yafei Li Yuen Wu | 2022 | CCS Chemistry2022，4，12： | 0 |
| 15 | On-demand assembly of optically levitated nanoparticle arrays in vacuum显示文摘Realizing a large-scale fully controllable quantum system is a challenging task in current physical research and has broad applications.In this work,we create a reconfigurable optically levitated nanoparticle array in vacuum.Our optically levitated nanoparticle array allows full control of individual nanoparticles to form an arbitrary pattern and detect their motion.As a concrete example,we choose two nanoparticles without rotation signals from an array to synthesize a nanodumbbell in situ by merging them into one trap.The nanodumbbell synthesized in situ can rotate beyond 1 GHz.Our work provides a platform for studying macroscopic many-body physics and quantum sensing. | JIANGWEI YAN XUDONG YU ZHENG VITTO HAN TONGCANG LI JING ZHANG | 2023 | Photonics Research2023，11，4： | 0 |
| 16 | Cobalt disulfide/carbon nanofibers with mesoporous heterostructure and excellent hydrophilicity for high energy density asymmetric supercapacitor显示文摘Herein,a unique mesoporous heterostructure(average pore size:15 nm)cobalt disulfide/carbon nanofibers(CoS_(2)/PCNFs)composite with excellent hydrophilicity(contact angle:23.5°)is prepared using polyethylene glycol(PEG)as a pore-forming agent.The CoS_(2)/PCNF electrode exhibits excellent cycle stability(95.2%of initial specific capacitance at 10 A·g^(-1)after 8000 cycles),good rate performance(46.5%at 10 A·g^(-1)),and high specific capacity(86.1 mAh·g^(-1)at 1 A·g^(-1),about 688.8 F·g^(-1)at 1 A·g^(-1)).Density functional theory(DFT)simulation elucidates that CoS_(2)tends to transfer substantial charges to CNF.As the center of positive charge,CoS_(2)is more likely to capture negative ions in the electrolyte,thus accelerating the ion diffusion process.The excellent properties of the electrode material can not only accelerate the electrochemical reaction kinetics,but also provide abundant redox-active sites and a high Faradaic capacity for the entire electrode due to the synergistic contributions of CoS_(2)nanoparticles,mesoporous heterostructure of PCNF,and admirable hydrophilicity of the composite material.A CoS_(2)/PCNF-0.25//AC(AC:activated carbon)asymmetric supercapacitor is assembled using CoS_(2)/PCNF-0.25 as the positive electrode and AC as the negative electrode,which possesses a high energy density(35.5 Wh·kg^(-1)at a power density of 824 W·kg^(-1))and superior cycling stability(maintaining over 98%of initial capacitance after 2000 cycles).In addition,the unique CoS_(2)/PCNF electrode is expected to be widely used in other electrochemical energy storage devices,such as lithium-ion batteries,sodium-ion batteries,lithium-sulfur batteries,etc. | Wenjie Liu Fen Qiao Jing Yang Jiaren Yuan Yi Xie Tao Wang Jinzhi Hu Jihua Zheng Rui Ren Xiaomin Kang Yan Zhao Jiangwei Zhang | 2023 | Nano Research2023，16，7： | 0 |
| 17 | Application of Microbiome in Forensics显示文摘Recent advances in next-generation sequencing technologies and improvements in bioinformatics have expanded the scope of microbiome analysis as a forensic tool.Microbiome research is concerned with the study of the compositional profile and diversity of microbial flora as well as the interactions between microbes,hosts,and the environment.It has opened up many new possibilities for forensic analysis.In this review,we discuss various applications of microbiome in forensics,including identification of individuals,geolocation inference,and post-mortem interval(PMI)estimation. | Jun Zhang Wenli Liu Halimureti Simayijiang Ping Hu Jiangwei Yan | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 0 |
| 18 | The Application of Next‑Generation Sequencing to Validate D12S391 Microvariation显示文摘Objective:In a paternity case,the D12S391 locus was reported as a mismatch.To confirm the existence of mutations and mutations come from father or mother.Methods:STR and next-generation sequencing technology were used to validate the sequence.Results:NGS showed the loss of one adenine between the 19.3 allele of the child and allele 20 of the mother.Conclusion:The NGS can be applied in the paternity to validate the mutation. | Qingxia Zhang Jinjie Liu He Ren Shuai Sun Yi Zhao Chong Chen Li Jia Yacheng Liu Jiangwei Yan | 2018 | Journal of Forensic Science and Medicine2018，4，2： | 0 |
| 19 | Identi cation of seed heat tolerance and its correlation with agronomic traits in Brassica napus L.显示文摘To better understand the effect of high temperature on seed viability, artificial aging treatments were implemented on 472 accessions of rapeseed (Brassica napus L.) by constant high temperature at 70℃for 8h. Results showed a remarkable impact of constant heat on seed germination. After heat treatment, considerable variation was found in seed germinability, some genotypes even lost the ability to germinate. The effect of accelerated aging was highly significant. Germination parameters varied among ecotypes. Seed viability varied with different origin, and was significantly and positively correlated with seed yield per plant and dry weight of aboveground parts per plant among 14 agronomic traits. Germination traits were positively correlated with oil contents. | Guizhen Gao Kun Xu Biyun Chen Xi Cheng Guixin Yan Jiangwei Qiao Qian Huang Xiaoming Wu | 2018 | Oil Crop Science2018，3，1： | 0 |
| 20 | Solvent sieving separators implement dual electrolyte for highvoltage lithium-metal batteries显示文摘Lithium-metal batteries(LMBs)based on high-voltage cathodes would deliver high specific energy density to meet the demand of future energy storage.However,developing liquid electrolytes with wide electrochemical window for high-energy LMBs is intrinsically challenging.Herein,we demonstrate metal-organic framework-functionalized separators(PE@MOF)with solvent sieving capability that implement dual electrolyte for LMBs.The capability of PE@MOF separator to block the diffusion of liquid electrolytes has been investigated.The PE@MOF separator notably suppresses solvents shuttling,enabling the independent optimization of cathode-electrolyte and anode-electrolyte interfaces.By adapting commercial carbonate and ether electrolytes on cathode and anode sides,respectively,robust cathode-electrolyte interphase(CEI)and solid electrolyte interface(SEI)have been built on both electrodes.The lifespan of LiCoO_(2)(LCO)|Li full cell has been notably extended when using dual electrolyte and the solvent-sieving PE@MOF separator.This work demonstrates a new strategy to separately optimize the local environments at electrodes and to develop high-energy LMBs using low-cost and commercially available electrolytes. | Yan Liu Qianqian Liu Youran Hong Yifei Xu Zerui Chen Wei Zhao Zhikun Hu Jiangwei Wang Hao Bin Wu | 2023 | Nano Research2023，16，4： | 0 |
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