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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Recompression in new levels after percutaneous vertebroplasty and kyphoplasty compared with conservative treatment显示文摘 | Xiaodong Yi Hailin Lu Fei Tian Yu Wang Chunde Li Hong Liu Xianyi Liu Hong Li | 2014 | Archives of Orthopaedic and Trauma Surgery2014，，1： | 1 |
| 3 | Difunctional Pluronic copolymer micelles for paclitaxel delivery: Synergistic effect of folate-mediated targeting and Pluronic-mediated overcoming multidrug resistance in tumor cell lines显示文摘 | Yongzhong Wang Li Yu Limei Han Xianyi Sha Xiaoling Fang | 2007 | International Journal of Pharmaceutics2007，，1： | 1 |
| 4 | Theoretical perspective on synthetic man-made life:Learning from the origin of life显示文摘Creating a man-made life in the laboratory is one of life science's most intriguing yet challenging problems.Advances in synthetic biology and related theories,particularly those related to the origin of life,have laid the groundwork for further exploration and understanding in this field of artificial life or man-made life.But there remains a wealth of quantitative mathematical models and tools that have yet to be applied to this area.In this paper,we review the two main approaches often employed in the field of man-made life:the top-down approach that reduces the complexity of extant and existing living systems and the bottom-up approach that integrates welldefined components,by introducing the theoretical basis,recent advances,and their limitations.We then argue for another possible approach,namely'bottom-up from the origin of life':Starting with the establishment of autocatalytic chemical reaction networks that employ physical boundaries as the initial compartments,then designing directed evolutionary systems,with the expectation that independent compartments will eventually emerge so that the system becomes free-living.This approach is actually analogous to the process of how life originated.With this paper,we aim to stimulate the interest of synthetic biologists and experimentalists to consider a more theoretical perspective,and to promote the communication between the origin of life community and the synthetic man-made life community. | Lu Peng Zecheng Zhang Xianyi Wang Weiyi Qiu Liqian Zhou Hui Xiao Chunxiuzi Liu Shaohua Tang Zhiwei Qin Jiakun Jiang Zengru Di Yu Liu | 2023 | Quantitative Biology2023，11，4： | 0 |
| 5 | Privacy-Preserving Multi-Keyword Fuzzy Adjacency Search Strategy for Encrypted Graph in Cloud Environment显示文摘In a cloud environment,outsourced graph data is widely used in companies,enterprises,medical institutions,and so on.Data owners and users can save costs and improve efficiency by storing large amounts of graph data on cloud servers.Servers on cloud platforms usually have some subjective or objective attacks,which make the outsourced graph data in an insecure state.The issue of privacy data protection has become an important obstacle to data sharing and usage.How to query outsourcing graph data safely and effectively has become the focus of research.Adjacency query is a basic and frequently used operation in graph,and it will effectively promote the query range and query ability if multi-keyword fuzzy search can be supported at the same time.This work proposes to protect the privacy information of outsourcing graph data by encryption,mainly studies the problem of multi-keyword fuzzy adjacency query,and puts forward a solution.In our scheme,we use the Bloom filter and encryption mechanism to build a secure index and query token,and adjacency queries are implemented through indexes and query tokens on the cloud server.Our proposed scheme is proved by formal analysis,and the performance and effectiveness of the scheme are illustrated by experimental analysis.The research results of this work will provide solid theoretical and technical support for the further popularization and application of encrypted graph data processing technology. | Bin Wu Xianyi Chen Jinzhou Huang Caicai Zhang Jing Wang Jing Yu Zhiqiang Zhao Zhuolin Mei | 2024 | Computers, Materials & Continua2024，78，3： | 0 |
| 6 | Effects of Microbial Fertilizers in Improving Acidic Tobacco-planting Soil and Tobacco Leaf Quality显示文摘[Objectives]This study was conducted to improve acidic soil and enhance the quality of tobacco leaves.[Methods]The effects of different microbial fertilizers on improving acidic tobacco-planting soil and tobacco leaf quality were investigated through plot experiments.[Results]The application of microbial fertilizers could improve the pH value of acidic soil,and composite microbial agent A showed the best application effect.The application of bio-organic fertilizer was beneficial to improving the contents of available phosphorus and available boron in acidic soil.The application of composite microbial agent A was beneficial to improving the contents of available phosphorus and available potassium in acidic soil,and could promote the growth of tobacco plants and improve the economic traits of flue-cured tobacco and the coordination of chemical components in tobacco leaves.The application of composite microbial agent B led to a downward trend in the content of available boron in acidic soil.The application of composite microbial agent B could promote the absorption of nutrients by tobacco plants,and improve their disease resistance and the quality of tobacco leaves.Due to the differences in functional microorganisms contained,the application effects of different microbial fertilizers in improving acidic tobacco-planting soil and improving tobacco leaf quality varied.Overall,the application of microbial fertilizers could increase soil pH,activate soil nutrients,promote tobacco growth,enhance disease resistance,increase tobacco output value,and improve tobacco quality.Microbial fertilizers have good application prospects in improving acidic soil and improving tobacco quality.[Conclusions]The application of microbial fertilizers to improve acidic tobacco-planting soil can ensure the normal growth and development of tobacco plants and the improvement of tobacco leaf quality,achieving high-quality and sustainable development of Zhaotong tobacco. | Xia NI Shungang SHEN Xianyi ZENG Dewen LI Yeming FU Min CHEN Chaokai YU Libing QI Ying-guo RUAN Changchong ZI Haohan GONG Guangjun HU Mengsheng ZHANG Xu ZHANG Shu PENG Hongbing LI | 2023 | Agricultural Biotechnology2023，12，2： | 0 |
| 7 | Effects of Different Chemical Fertilizer Reduction Techniques on Flue-cured Tobacco Production显示文摘[Objectives]This study was conducted to find out the most suitable special formula fertilizer for flue-cured tobacco production in tobacco-growing areas of Zhaotong City,so as to provide a basis for scientific fertilization and reduced application of inorganic fertilizers with improved efficiency in tobacco production in Zhaotong City.[Methods]Different formulas of special base fertilizer and special topdressing for tobacco were designed by optimizing and adjusting the application amounts and proportions of nitrogen,phosphorus,potassium and medium trace elements in fertilizer formulas,and the formulas of special base fertilizer and special topdressing for flue-cured tobacco production were selected through a field plot experiment.[Results]The combination of special base fertilizer and special topdressing was conducive to the early growth and rapid growth of tobacco plants under the condition of reduced fertilizer application,and the treatment using organic-inorganic compound fertilizer as the special base fertilizer was the most obvious,with an average growth period of two days increased.Compared with conventional fertilization,the yield,output value,average price,proportion of superior tobacco and proportion of medium and superior tobacco increased in the organic-inorganic compound fertilizer treatment,with the yield increasing by 5.96%,the output value increasing by 17.08%,the average price increasing by 10.49%,the proportion of superior tobacco increasing by 4.63%,and the proportion of medium and superior tobacco increasing by 2.44%.It was concluded from indexes including growth period,agronomic traits,disease incidence and economic traits,the fertilization mode of organic-inorganic compound fertilizer with the addition of trace elements(boron,magnesium and zinc)applied as the base fertilizer and nitrogen and potassium topdressing was most efficient and economic.[Conclusions]This study provides a basis for scientific fertilization and reduced application of inorganic fertilizers with improved efficiency in tobacco production in Zhaotong City. | Longfeng GUI Lei XIA Jing YANG Wei YAN Yu ZHOU Yuzhong ZHOU Haohan GONG Mengsheng ZHANG Yeming FU Xianyi ZENG Xia NI | 2023 | Agricultural Biotechnology2023，12，6： | 0 |
| 8 | Long-term exercise training inhibits inflammation by suppressing hippocampal NLRP3 in APP/PS1 mice显示文摘Behavioral experiments have demonstrated that long-term physical exercise can be beneficial for learning and memory dysfunction caused by neuroinflammation in Alzheimer's disease(AD).However,the molecular mechanism remains poorly understood due to a lack of sufficient pertinent biochemical evidence.We investigated the potential effect of long-term physical exercise on cognition and hippocampal gene and protein expression changes in a transgenic AD mouse model.Following twenty weeks of treadmill exercise,transgenic AD mice showed improvement in cognitive functions and downregulation of Nod-like receptor protein 3(NLRP3)(p<0.01),interleukin-1beta(IL-1β)(p<0.05),and amyloid-β1-42(Aβ1-42)(p<0.05)expression levels.In addition,we observed significant reductions of microglial activation and hippocampal neuronal damage in the exercised AD mice(p<0.01),which might be a result of the downregulation of NLRP3-mediated signaling and neuroinflammatory responses.As neuronal damage due to inflammation might be a likely cause of AD-associated cognitive dysfunction.Our results suggested that the anti-inflammatory effects of exercise training involved downregulating the expression of key inflammatory factors and might play an important role in protecting hippocampal neurons against damage during the course of AD. | Xue Li Yu Jin Xianyi Ding Tongyang Zhu Changling Wei Li Yao | 2023 | Sports Medicine and Health Science2023，5，4： | 0 |
| 9 | Optimal time of acute kidney injury microenvironment for proliferation and differentiation of mesenchymal stem cells显示文摘Objective To investigate the optimal timing of acute kidney injury environment for proliferation and differentiation of mesenchymal stem cells(MSCs).Methods MSCs were co-cultured with kidney homogenate at different ischemia/reperfusion(I/R)time points.The proliferation was reflected by CCK-8assay and cell number counting.The differentiation was reflected by cell shape and CK-18RNA expression.Results After 15dculture,shape of MSCs cultured with kidney homogenate at 72htime point was much more round and ellipsoidal,and the cells had a cobble like appearance.Cell number,CCK-8and CK-18level of MSCs cultured with kidney homogenate at 72htime point was significantly higher comparing with other time points.Conclusions 72hpost I/R was the optimal timing for proliferation and differentiation of MSCs. | Wu Chen Zhang Yixiong Tang Xianyi Jiang Yu Zou Lianhong | 2020 | 实用休克杂志(中英文)2020，4，2： | 0 |
| 10 | Preparation of High Quality p-Type Diamond Thin Films by Thermal Chemical Vapor Deposition显示文摘P-type semiconducting polycrystalline diamond thin films doped with boron were synthesized on single crystalline silicon substrate by thermal chemical vapor deposition from a tungsten filament and placing boron-contained substance(boron nitride or elemental boron)on sample holder.The films were determined to be the high quality diamond by Raman spectroscopy,X-ray diffraction and scanning electron microscope measurements.The doping properties of boron were measured by Hall method and infrared absorption. | YU San JIN Zengsun LÜ Xianyi ZOU Guangtian | 1991 | Chinese Physics Letters1991，8，4： | 0 |
| 11 | A Dual Model Watermarking Framework for Copyright Protection in Image Processing Networks显示文摘Image processing networks have gained great success in many fields,and thus the issue of copyright protection for image processing networks hasbecome a focus of attention. Model watermarking techniques are widely usedin model copyright protection, but there are two challenges: (1) designinguniversal trigger sample watermarking for different network models is stilla challenge;(2) existing methods of copyright protection based on trigger swatermarking are difficult to resist forgery attacks. In this work, we propose adual model watermarking framework for copyright protection in image processingnetworks. The trigger sample watermark is embedded in the trainingprocess of the model, which can effectively verify the model copyright. And wedesign a common method for generating trigger sample watermarks based ongenerative adversarial networks, adaptively generating trigger sample watermarksaccording to different models. The spatial watermark is embedded intothe model output. When an attacker steals model copyright using a forgedtrigger sample watermark, which can be correctly extracted to distinguishbetween the piratical and the protected model. The experiments show that theproposed framework has good performance in different image segmentationnetworks of UNET, UNET++, and FCN (fully convolutional network), andeffectively resists forgery attacks. | Yuhang Meng Xianyi Chen Xingming Sun Yu Liu Guo Wei | 2023 | Computers, Materials & Continua2023，，4： | 0 |
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