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| 1 | Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs显示文摘AIM: To evaluate the effects of a portocaval shunt on the decrease of excessive portal flow for the prevention of sinusoidal microcirculatory injury in extremely smallfor-size liver transplantation in pigs.METHODS: The right lateral lobe of pigs, i.e. the 25%of the liver, was transplanted orthotopically. The pigs were divided into two groups: graft without portocaval shunt (n = 11) and graft with portocaval shunt (n=11).Survival rate, portal flow, hepatic arterial flow, and histological findings were investigated.RESULTS: In the group without portocaval shunt, all pigs except one died of liver dysfunction within 24 h after transplantation. In the group with portocaval shunt,eight pigs survived for more than 4 d. The portal flow volumes before and after transplantation in the group without portocaval shunt were 118.2±26.9 mL/min/100 g liver tissue and 270.5±72.9 mL/min/100 g liver tissue,respectively. On the other hand, in the group with portocaval shunt, those volumes were 124.2±27.8 mL/min/100 g liver tissue and 42.7±32.3 mL/min/100 g liver tissue, respectively (P<0.01). As for histological findings in the group without portocaval shunt, destruction of the sinusoidal lining and bleeding in the peri-portal areas were observed after reperfusion, but these findings were not recognized in the group with portocaval shunt.CONCLUSION: These results suggest that excessive portal flow is attributed to post transplant liver dysfunction after extreme small-for-size liver transplantation caused by sinusoidal microcirculatory injury. | Hong-Sheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Takeshi Asakura Hiroo Masuoka Takashi Aiso Keisuke Fukushima Tomohiro Narita Hideyuki Yamaya Atsushi Nakamura Satoshi Sekiguchi Naoki Kawagishi Akira Sato Susumu Satomi | 2005 | World Journal of Gastroenterology2005，11，44： | 8 |
| 2 | Coexistence of esophageal superficial carcinoma and multiple leiomyomas:A case report显示文摘平滑肌瘤是食管的最普通的良性瘤。他们通常作为单个损害或作为二或三个小瘤发生。仅仅包括超过 10 个小瘤的食道的多重平滑肌瘤的二个案例以前被报导了。而且,有食道的有鳞的房间癌覆闷死粘膜下层肿瘤的很少报告。我们描述作为有表面的食道的癌症与二或三个平滑肌瘤小瘤共存被诊断的一个 71 岁的人。在外科期间, 10 或一直不外科手术前地是明显的更多的小瘤在整个食管在粘膜下层和肌层是摸得出的。当食道的癌症的内部转移被怀疑,我们认为另外的淋巴是腺切除术,但是因为病人的严重血缺氧,不得不排除这种选择。显微镜检查表明所有小瘤是平滑肌瘤(20 损害,在直径的多达 3 厘米) ,并且癌房间的那侵略被限制到粘膜下层层 overlying 一个相对大的平滑肌瘤。这是与众多的独居的平滑肌瘤共存的表面的食道的癌症的第一份报告。多重极小的平滑肌瘤经常也在一个癌损害罐头的底作为内部转移,和一个平滑肌瘤被误诊作为肿瘤侵略被误诊。现在的案例证明那精确诊断与共存为病人的管理被要求表面的食道的癌症和多重平滑肌瘤。 | Takeshi Iwaya Chihaya Maesawa Noriyuki Uesugi Toshimoto Kimura Kenichiro Ikeda Yusuke Kimura Shingo Mitomo Kaoru Ishida Nobuhiro Sato Go Wakabayashi | 2006 | World Journal of Gastroenterology2006，12，28： | 7 |
| 3 | Multiple primary malignant neoplasms of three early cancer lesions: a case report显示文摘多重主要的恶意的瘤(MPMN ) 很少被报导,为这些病人给早诊断和合适的治疗是重要的。这里在上面的胃肠的道与伴随物三早阶段癌症损害报导了 62 岁的人的一个案例,所有哪个被内视镜检查法检测。第一是在在内视镜检查法下面的胃的尖部分的 llc 类型损害,它组织学地被证实是区分得好的 adenocarcinoma.The 病人经历了的 mucosal 为在内视镜的治疗的失败以后的损害的标准激进的 gastrectomy。另外的二个瘤在后续期间被观察并且被综合作为早阶段损害显示从内视镜检查法,内视镜的 ultrasonography,计算断层摄影术和活体检视的信息。一个人作为一个 hyperemic 补丁显示了(3cm 吗?? | ZHANG Wan-jun QIAN Xiao-ping SHI Yu PAN Wen-sheng XU Xiang YE Zai-yuan WU Liang-qin Takeshi Terai Nobuhiro Sato Sumio Watanabe | 2011 | Chinese Medical Journal2011，，8： | 4 |
| 4 | Efficacy and adverse events of cold vs hot polypectomy: A meta-analysis显示文摘AIM: To compare previously reported randomized controlled studies(RCTs) of cold and hot polypectomy, we systematically reviewed and clarify the utility of cold polypectomy over hot with respect to efficacy and adverse events.METHODS: A meta-analysis was conducted to evaluate the predominance of cold and hot polypectomy for removing colon polyps. Published articles and abstracts from worldwide conferences were searched using the keywords 'cold polypectomy'. RCTs that compared either or both the effects or adverse events of cold polypectomy with those of hot polypectomy were collected. The patients' demographics, endoscopic procedures, No. of examined lesions, lesion size, macroscopic and histologic findings, rates of incomplete resection, bleeding amount, perforation, and length of procedure were extracted from each study. A forest plot analysis was used to verify the relative strength of the effects and adverse events of each procedure. A funnel plot was generated to assess the possibility of publication bias.RESULTS: Ultimately, six RCTs were selected. No significant differences were noted in the average lesion size(less than 10 mm) between the cold and hot polypectomy groups in each study. Further, the rates of complete resection and adverse events, including delayed bleeding, did not differ markedly between cold and hot polypectomy. The average procedural time in the cold polypectomy group was significantly shorter than in the hot polypectomy group.CONCLUSION: Cold polypectomy is a time-saving procedure for removing small polyps with markedly similar curability and safety to hot polypectomy. | Mikihiro Fujiya Hiroki Sato Nobuhiro Ueno Aki Sakatani Kazuyuki Tanaka Tatsuya Dokoshi Shugo Fujibayashi Yoshiki Nomura Shin Kashima Takuma Gotoh Junpei Sasajima Kentaro Moriichi Jiro Watari Yutaka Kohgo | 2016 | World Journal of Gastroenterology2016，22，23： | 3 |
| 5 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 2 |
| 6 | Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals显示文摘 | Kenichi Ikejima Hajime Honda Mutsuko Yoshikawa Miyoko Hirose Tsuneo Kitamura Yoshiyuki Takei Nobuhiro Sato | 2001 | Hepatology2001，，2： | 2 |
| 7 | Malignant lymphoma in the ileum diagnosed by double-balloon enteroscopy显示文摘A 73-year old man presented with abdominal pain. A tumor with central ulceration was observed in the ileum using double-balloon enteroscopy. Histological findings of the biopsy specimens were consistent with malignant lymphoma. Double-balloon enteroscopy confirmed the diagnosis of a malignant lymphoma tumor which was surgically resected. The patient is still in complete remission now. | Kazuko Beppu Taro Osada Akihito Nagahara Naoto Sakamoto Tomoyoshi Shibuya Masato Kawabe Takeshi Terai Toshifumi Ohkusa Tatsuo Ogihara Nobuhiro Sato Toshiki Kamano Yasuo Hayashida Sumio Watanabe | 2007 | World Journal of Gastroenterology2007，13，24： | 1 |
| 8 | RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules显示文摘 | Koichi Hashimoto Kei Ishibashi Ken Ishioka Dongchi Zhao Masatoki Sato Shinichiro Ohara Yusaku Abe Yukihiko Kawasaki Yuka Sato Shin-ichi Yokota Nobuhiro Fujii Ray Stokes Peebles Mitsuaki Hosoya Tatsuo Suzutani | 2009 | Virology2009，，2： | 1 |
| 9 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 10 | Poor prognosis of recurrent aborters with either maternal or paternal reciprocal translocations显示文摘 | Mayumi Sugiura-Ogasawara Yasuhiko Ozaki Takeshi Sato Nobuhiro Suzumori Kaoru Suzumori | 2004 | Fertility and Sterility2004，，2： | 1 |
| 11 | Development of ferritic stainless steel YUS450 with excellent heat resistance for automotive exhaust systems显示文摘 | Fujita Nobuhiro Ohmura Keiichi Sato Eiji | 1996 | Nippon Steel Technical Report1996，，361： | 1 |
| 12 | microRNA expression is able to predict response to chemoradiotherapyin rectal cancer显示文摘 | Masanori Hotchi Mitsuo Shimada Nobuhiro Kurita Takashi Iwata Hirohiko Sato Shinya Morimoto Kozo Yoshikawa Jun Higashijima Tomohiko Miyatani | 2013 | Molecular and Clinical Oncology2013，，： | 1 |
| 13 | Treatment of functional dyspepsia with antianxiety or antidepressive agents: systematic review显示文摘 | Mariko Hojo Hiroto Miwa Tetsuji Yokoyama Toshifumi Ohkusa Akihito Nagahara Masato Kawabe Daisuke Asaoka Yuko Izumi Nobuhiro Sato | 2005 | Journal of Gastroenterology2005，，11： | 1 |
| 14 | Role of Mitochondria in Liver Pathophysiology 显示文摘 | Shunhei Yamashina Nobuhiro Sato Kazuyoshi Kon | 2009 | Drug Discovery Today : Disease Mechanisms2009，6，14： | 1 |
| 15 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 16 | Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model显示文摘 | Takeshi Asakura Nobuhiro Ohkohchi Takashi Orii Nozomi Koyamada Shigeki Tsukamoto Masahide Sato Yoshitaka Enomoto Masahiro Usuda Susumu Satomi | 2003 | Transplant International2003，，6： | 1 |
| 17 | Chronic effect of intragastric ammonia on gastric mucosal structures in rats显示文摘 | Dr. Sunao Kawano MD Masahiko Tsujii MD Hideyuki Fusamoto MD Nobuhiro Sato MD Takenobu Kamada MD | 1991 | Digestive Diseases and Sciences1991，，1： | 1 |
| 18 | Effect of Antibiotics, Levofloxacin and Fosfomycin, on a Mouse Model with Escherichia coli O157 Infection显示文摘 | Emiko Isogai Hiroshi Isogai Shunji Hayashi Toru Kubota Koichi Kimura Nobuhiro Fujii Tsuyoshi Ohtani Kenichi Sato | 2000 | Microbiology and Immunology2000，，2： | 1 |
| 19 | H. pylori and gastric cancer: the Asian enigma显示文摘 | Hiroto Miwa Mae F Go Nobuhiro Sato | 2002 | The American Journal of Gastroenterology2002，，： | 1 |
| 20 | Endoscopic Subtotal Thyroidectomy for Patients with Graves’ Disease显示文摘 | Masahide Yamamoto Akira Sasaki Hiroshi Asahi Yutaka Shimada Nobuhiro Sato Jun Nakajima Rie Mashima Kazuyoshi Saito | 2001 | Surgery Today2001，，1： | 1 |
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