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| 1 | Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs显示文摘AIM: To evaluate the effects of a portocaval shunt on the decrease of excessive portal flow for the prevention of sinusoidal microcirculatory injury in extremely smallfor-size liver transplantation in pigs.METHODS: The right lateral lobe of pigs, i.e. the 25%of the liver, was transplanted orthotopically. The pigs were divided into two groups: graft without portocaval shunt (n = 11) and graft with portocaval shunt (n=11).Survival rate, portal flow, hepatic arterial flow, and histological findings were investigated.RESULTS: In the group without portocaval shunt, all pigs except one died of liver dysfunction within 24 h after transplantation. In the group with portocaval shunt,eight pigs survived for more than 4 d. The portal flow volumes before and after transplantation in the group without portocaval shunt were 118.2±26.9 mL/min/100 g liver tissue and 270.5±72.9 mL/min/100 g liver tissue,respectively. On the other hand, in the group with portocaval shunt, those volumes were 124.2±27.8 mL/min/100 g liver tissue and 42.7±32.3 mL/min/100 g liver tissue, respectively (P<0.01). As for histological findings in the group without portocaval shunt, destruction of the sinusoidal lining and bleeding in the peri-portal areas were observed after reperfusion, but these findings were not recognized in the group with portocaval shunt.CONCLUSION: These results suggest that excessive portal flow is attributed to post transplant liver dysfunction after extreme small-for-size liver transplantation caused by sinusoidal microcirculatory injury. | Hong-Sheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Takeshi Asakura Hiroo Masuoka Takashi Aiso Keisuke Fukushima Tomohiro Narita Hideyuki Yamaya Atsushi Nakamura Satoshi Sekiguchi Naoki Kawagishi Akira Sato Susumu Satomi | 2005 | World Journal of Gastroenterology2005，11，44： | 8 |
| 2 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 2 |
| 3 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 4 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 5 | Intestinal obstruction caused by colonic metastasis from intrahepatic cholangiocarcinoma 6?years after removal of the primary tumor: report of a case显示文摘 | Kazuaki Tokodai Naoki Kawagishi Shigehito Miyagi Ikuo Takeda Kazushige Sato Yorihiro Akamatsu Satoshi Sekiguchi Kazuyuki Ishida Susumu Satomi | 2012 | Surgery Today2012，，8： | 1 |
| 6 | Conditional gene expression in hepatitis C virus transgenic mice without induction of severe liver injury using a non-inflammatory Cre-expressing adenovirus显示文摘 | Tomoko Chiyo Satoshi Sekiguchi Masahiro Hayashi Yoshimi Tobita Yumi Kanegae Izumu Saito Michinori Kohara | 2011 | Virus Research2011，，1： | 1 |
| 7 | Profile Simulation of SU-8 Thick Film Resist 显示文摘 | Yoshihisa Sensu Sekiguchi Atsushi Mori Satoshi | 2005 | Journal of Photoploymer Science and Technology(S0914-9244)2005，18，1： | 1 |
| 8 | Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract显示文摘 | Dr. Osamu Kawamura MD Toshikazu Sekiguchi MD Zen Itoh MD Satoshi Omura MD | 1993 | Digestive Diseases and Sciences1993，，6： | 1 |
| 9 | Overlay weaver: An overlay construction toolkit显示文摘 | Kazuyuki Shudo Yoshio Tanaka Satoshi Sekiguchi | 2008 | Computer Communications (Special Issue on Foundations of Peer-to-Peer Computing) Elsevier Science2008，31，2： | 1 |
| 10 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 11 | Estimation of point of zero charge for activated carbon treated with stmospheric pressure non-thermal oxygen plasmas 显示文摘 | SATOSHI KODAMA HIDETOSHI SEKIGUCHI | 2006 | Thin Solid Films2006，，： | 1 |
| 12 | Single-Seed Casting Large-Size Monocrystalline Silicon for High-Efflciency and Low-Cost Solar Cells显示文摘To grow high-quality and large-size monocrystalline silicon at low cost, we proposed a single-seed casting technique. To realize this technique, two challenges—polycrystalline nucleation on the crucible wall and dislocation multiplication inside the crystal—needed to be addressed. Numerical analysis was used to develop solutions for these challenges. Based on an optimized furnace structure and operating conditions from numerical analysis, experiments were performed to grow monocrystalline silicon using the single-seed casting technique. The results revealed that this technique is highly superior to the popular high-performance multicrystalline and multiseed casting mono-like techniques. | Bing Gao Satoshi Nakano Hirofumi Harada Yoshiji Miyamura Takashi Sekiguchi Koichi Kakimoto | 2015 | Engineering2015，1，3： | 1 |
| 13 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 14 | Polyarteritis nodosa clinically mimicking nonocclusive mesenteric ischemia显示文摘Here, we present the case of a 74-year-old Japanese man with segmental intestinal necrosis, which developed after treatment with pulsed methylprednisolone for mononeuritis multiplex. The patient was weakly positive for myeloperoxidase (MPO)-anti-neutrophil cytoplasmic antibody (ANCA). Computed tomography and surgical findings were compatible with nonocclusive mesenteric ischemia (NOMI). He underwent small intestinal resection by emergency surgery and an intestinal fistula was made. Pathologically, necrotizing vasculitis with fibrinoid necrosis was present in medium to small-sized arteries, which was equivalent to Arkin's classification Ⅱ-Ⅳ. Most of the arteries had fibrous intimal thickening, which was considered to obstruct the arteries and thus cause segmental intestinal necrosis. A diagnosis of polyarteritis nodosa (PAN) was made, and intravenous cyclophosphamide pulse therapy was added to the therapeutic regimen. This patient was successfully treated with these multidisciplinary therapies and his stoma was finally closed. This is a very rare and indicative case of PAN weakly positive for MPO-ANCA and clinically mimicking NOMI, which occurred even after treatment with pulsed methylprednisolone. | Tsuyoshi Shirai Hiroshi Fujii Shinichiro Saito Tomonori Ishii Hideyuki Yamaya Shigehito Miyagi Satoshi Sekiguchi Naoki Kawagishi Masato Nose Hideo Harigae | 2013 | World Journal of Gastroenterology2013，19，23： | 1 |
| 15 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Hiroo Masuoka Satoshi Sekiguchi Naoki Kawagishi Keisei Fujimori Akira Sato Susumu Satomi | 2006 | World Journal of Surgery2006，，11： | 1 |
| 16 | Late-onset non-islet cell tumor hypoglycemia: A case report显示文摘BACKGROUND Hypoglycemia due to non-insulin-producing tumors is referred to as non-islet cell tumor hypoglycemia(NICTH).As NICTH is a rare lesion,the natural course of NICTH is not well understood.We report a case of NICTH that was observed 30 years before the onset of hypoglycemia.CASE SUMMARY A 50-year-old man was diagnosed with an abnormal right chest shadow during a routine X-ray examination,but no further examination was undertaken because the lesion appeared benign.Thirty years after the tumor discovery,the patient was admitted to the hospital with symptoms of severe hypoglycemia,which was diagnosed as NICTH based on a complete examination.The tumor was resected and found to be a solitary fibrous mass(15.6 cm×13.7 cm×10.4 cm);thereafter,the patient’s blood glucose levels normalized and he completely recovered.CONCLUSION NICTH can have an acute onset,even if the tumor has been present and asymptomatic over a long time period. | Shunichi Matsumoto Eijiro Yamada Yasuyo Nakajima Naoki Yamaguchi Takashi Okamura Toshiki Yajima Satoshi Yoshino Kazuhiko Horiguchi Emi Ishida Masashi Yoshikawa Jun Nagaoka Sho Sekiguchi Mai Sue Shuichi Okada Izumi Fukuda Ken Shirabe Masanobu Yamada | 2021 | World Journal of Clinical Cases2021，9，1： | 0 |
| 17 | Liver cell adenoma showing sequential alteration of radiological findings suggestive of well-differentiated hepatocellular carcinoma显示文摘A liver tumor 35 mm in diameter was found incidentally in a 40-year-old woman who had no history of liver diseases or the use of oral contraceptives.Radiological diagnostics showed the typical findings of liver cell adenoma(LCA).Dynamic computed tomography revealed that the tumor showed a homogenous enhancement in the arterial phase and almost the same enhancement as the surrounding liver parenchyma in the delayed phase.The tumor was found to contain fat on magnetic resonance imaging.A benign fat containing liver tumor was suggested.However,radiological findings altered,which caused us to suspect that a welldifferentiated hepatocellular carcinoma(HCC)containing fat was becoming dedifferentiated.Partial hepatectomy was performed and the pathological findings showed the typical findings of LCA.This case was an extremely rare LCA,which had no background of risk for LCA and developed the sequential alteration of the radiological findings to suspect well-differentiated HCC. | Takayuki Kogure Yoshiyuki Ueno Satoshi Sekiguchi Kazuyuki Ishida Takehiko Igarashi Yuta Wakui Takao Iwasaki Tooru Shimosegawa | 2009 | World Journal of Gastroenterology2009，15，10： | 0 |
| 18 | SIGMA-1数据流巨型机-对新一代巨型机系统的挑战显示文摘SIGMA-1是一种很有前途的、基于数据流体系结构的实用计算机原型。它在性能上超过了传统的冯氏计算机。这种大规模数据流机用于科学技术计算。它正由日本通产省的电子技术实验室进行最后阶段的设计和制造。本文概述了SIGMA-1的系统结构,讨论了最近进行的性能测试,同时还给出了为达到SIGMA-1计划中提出的100MFLOPS性能指标所作的设计决策和有关体系结构的问题。最后简述了SIGMA-1计划的历史。 | KEI HIRAKI KENJI NISHIDA SATOSHI SEKIGUCHI TOSHIO SHIMADA TOSHITSUGU YUBA 黄志毅 | 1989 | 计算机工程与科学1989，11，3： | 0 |
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