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| 1 | Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement显示文摘Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City,China,by January 30,2020,a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in China.Among the confirmed cases,1527 were severe cases,171 had recovered and been discharged at home,and 213 died.And among these cases,a total of 28 children aged from 1 month to 17 years have been reported in China.For standardizing prevention and management of 2019-nCoV infections in children,we called up an experts' committee to formulate this experts' consensus statement.This statement is based on the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (the fourth edition) (National Health Committee) and other previous diagnosis and treatment strategies for pediatric virus infections.The present consensus statement summarizes current strategies on diagnosis,treatment,and prevention of 2019-nCoV infection in children. | Kunling Shen Yonghong Yang Tianyou Wang Dongchi Zhao Yi Jiang Runming Jin Yuejie Zheng Baoping Xu Zhengde Xie Likai Lin Yunxiao Shang Xiaoxia Lu Sainan Shu Yan Bai Jikui Deng Min Lu Leping Ye Xuefeng Wang Yongyan Wang Liwei Gao | 2020 | World Journal of Pediatrics2020,16,3: | 56 |
| 2 | A respiratory syncytial virus persistent-infected cell line system reveals the involvement of SOCS1 in the innate antiviral response显示文摘HEp-2 cells persistently infected with respiratory syncytial virus(RSV) are a heterogeneous mixture of viral antigen-positive and-negative variants; however, the mechanism through which viral replication becomes latent remains unclear. In this study, we investigated the potential mechanism by which RSV escapes from innate immune surveillance. Persistent-infected RSV HEp-2 cells were isolated and cell clones were passaged. The RSV-persistent cells produced viruses at a lower titer, resisted wild-type RSV re-infection, and secreted high levels of interferon-β(IFN-β), macrophage inflammatory protein-1α(Mip-1α), interleukin-8(IL-8), and Rantes. Toll-like receptor 3(TLR3), retinoic acid inducible gene-I(RIG-I), and suppressor of cytokine signaling 1(SOCS1) levels were upregulated in these cells. The silencing of TLR3 m RNA decreased the expression of SOCS1 protein and the secretion of cytokines. RSV-persistent cells are in an inflammatory state; upregulation of SOCS1 is related to the TLR3 signaling pathway, which could be associated with the mechanism of viral persistence. | Junwen Zheng Pu Yang Yan Tang Dongchi Zhao | 2015 | Virologica Sinica2015,30,3: | 1 |
| 3 | RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules显示文摘 | Koichi Hashimoto Kei Ishibashi Ken Ishioka Dongchi Zhao Masatoki Sato Shinichiro Ohara Yusaku Abe Yukihiko Kawasaki Yuka Sato Shin-ichi Yokota Nobuhiro Fujii Ray Stokes Peebles Mitsuaki Hosoya Tatsuo Suzutani | 2009 | Virology2009,,2: | 1 |
| 4 | Internal and external anti-corrosion coating technologyfor high-grade steel mechanical properties of pipelinesteel 显示文摘 | Liu Dongchi Zhang Chenpeng Wang Hong | 2007 | Welded Pipe and Tube2007,30,1: | 1 |
| 5 | AExperimentonthe Effect of Magnetic Field upon Ni002 Leveler显示文摘 | DongChi | 1987 | Crustal Deformation and Earthquake1987,7,3: | 1 |
| 6 | Investigation on the influence of vortex generator on particle resuspension显示文摘The vortex generator(VG)and its well-known effect in flow optimization are widely studied and employed across different engineering sectors.However,while the same working principles of VG may be well suited for the applications on surface-cleaning technologies,such promising potential is hardly,if any,explored in the published literature.Therefore,in the present study,the influence on flow-induced particle resuspension brought by a rectangular vG in a channel flow is investigated with the help of highfidelity computational fluid dynamics simulations.Substantial increases of particle removal forces and resuspension rates are discovered in long,strip-like regions with reduced boundary-layer thickness resulted from the vG-induced vortices,and the enhancement effect is especially significant for configurations with the VG installed at a greater angle of attack.It is also shown that while the resuspension enhancements on the lower and the upper surfaces of the channel exhibit distinct statistical characteristics,having a VG in the channel improves the overall particle-removing capability of the channel flow by introducing higher surface-averaged removal forces and particle resuspension rates.Last but not least,the increase of resuspension rate is especially significant for the smaller,micron-scale particles which are otherwise hardly disturbed by a VG-less channel flow,and such resuspension-enhancement effectgenerally subsides with increasing particle size. | Dongchi Yu Jun-Li Lin Jin-Han Xie | 2024 | Particuology2024,86,3: | 0 |