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| 1 | Quantitative Trait Loci Mapping for Leaf Length and Leaf Width in Rice cv.IR64 Derived Lines显示文摘The present study was conducted to identify quantitative trait loci(QTLs) for leaf size traits in IR64 introgression lines(INLs).For this purpose,selected F2 populations derived from crosses between recurrent parent IR64 and its derived INLs,unique for leaf length and leaf width,were used to confirm QTLs.A total of eight QTLs,mapped on three chromosomes,were identified for the four leaf size traits in six F2 populations.A QTL for leaf length,qLLnpt-1,in HKL69 was identified around simple sequence repeat(SSR) marker RM3709 on chromosome 1.Two QTLs for flag leaf length,qFLLnpt-2 and qFLLnpt-4,in HFG39 were indentified on chromosomes 2 and 4,respectively.For flag leaf width,a QTL,qFLWnpt-4,in HFG39 was identified around RM17483 on chromosome 4.While another QTL for flag leaf width,qFLWnpt-1,in HFG27 was identified around RM3252 on chromosome 1.A QTL for leaf width,qLWnpt-2,in HKL75 was identified around RM7451 on chromosome 2.For leaf width,two QTLs,qLWnpt-4a,qLWnpt-4b,in HKL48 and HKL99 were identified around RM7208 and RM6909,respectively on chromosome 4.Results from this study suggest the possibilities to use marker-assisted selection and pyramiding these QTLs to improve rice water productivity. | Muhammad Farooq Analiza G.Tagle Rizza E.Santos Leodegario A.Ebron Daisuke Fujita Nobuya Kobayashi | 2010 | Journal of Integrative Plant Biology2010，52，6： | 8 |
| 2 | Characterization of QTL for unique agronomic traits of new-plant-type rice varieties using introgression lines of IR64显示文摘To enhance the yield potential of an elite indica rice cultivar,an introgression(BC_3-derived) line of IR64,YTH288,was developed using a new-plant-type cultivar,IR66215-44-2-3,as a donor parent.YTH288 has agronomically valuable characteristics such as large panicles,few unproductive tillers,and large leaves inherited from NPT.To identify the genetic basis of these traits,we used 167 F_2 plants derived from a cross between IR64 and YTH288 to conduct QTL analysis for five agronomic traits:days to heading(DTH),culm length(CL),flag leaf length(FLL),flag leaf width(FLW),and filled spikelet number per panicle(FSN).Six putative QTL were detected:four on chromosome4(for CL,FLL,FLW,and FSN) and two on chromosome 2(for DTH and FLL).All QTL with the IR66215-44-2-3 allele,except that for FLL on chromosome 2,had positive effects on each trait.To confirm the effects of these putative QTL,we developed NILs with the IR64 genetic background by marker-assisted selection.We observed significant differences in several agronomic traits between IR64 and NILs that carried these QTL on chromosomes2 and 4.Additionally,four IR64-NILs carrying chromosomal segments derived from different NPT varieties on the long arm of chromosome 4 exhibited similar pleiotropic To enhance the yield potential of an elite indica rice cultivar, an introgression(BC3-derived) line of IR64, YTH288, was developed using a new-plant-type cultivar,IR66215-44-2-3, as a donor parent. YTH288 has agronomically valuable characteristics such as large panicles, few unproductive tillers, and large leaves inherited from NPT.To identify the genetic basis of these traits, we used 167 F2 plants derived from a cross between IR64 and YTH288 to conduct QTL analysis for five agronomic traits: days to heading(DTH), culm length(CL), flag leaf length(FLL), flag leaf width(FLW), and filled spikelet number per panicle(FSN). Six putative QTL were detected: four on chromosome4(for CL, FLL, FLW, and FSN) and two on chromosome 2(for DTH and FLL). All QTL with the IR66215-44-2-3 allele, except that for FLL on chromosome 2, had positive effects on each trait. To confirm the effects of these putative QTL, we developed NILs with the IR64 genetic background by marker-assisted selection. We observed significant differences in several agronomic traits between IR64 and NILs that carried these QTL on chromosomes2 and 4. Additionally, four IR64-NILs carrying chromosomal segments derived from different NPT varieties on the long arm of chromosome 4 exhibited similar pleiotropiceffects for unique agronomic traits. These NILs can be used as research materials for studying each trait and as breeding materials for yield improvement of indica rice cultivars. | Analiza G.Tagle Daisuke Fujita Leodegario A.Ebron Mary Jeanie Telebanco-Yanoria Kazuhiro Sasaki Tsutomu Ishimaru Yoshimichi Fukuta Nobuya Kobayashi | 2016 | The Crop Journal2016，4，1： | 2 |
| 3 | Vitamin D receptor expression is associated with colon cancer in ulcerativecolitis显示文摘 | Koji Wada Hiroaki Tanaka Kiyoshi Maeda Toru Inoue Eiji Noda Ryosuke Amano Naoshi Kubo Kazuya Muguruma Nobuya Yamada Masakazu Yashiro Tetsuji Sawada Bunzo Nakata Masaichi Ohira Kosei Hirakawa | 2009 | Oncology Reports2009，，5： | 2 |
| 4 | Sulfonylurea and glinide reduce insulin content, functional expression of K ATP channels, and accelerate apoptotic β-cell death in the chronic phase显示文摘 | Akira Takahashi Kazuaki Nagashima Akihiro Hamasaki Naomitsu Kuwamura Yukiko Kawasaki Hiroki Ikeda Yuichiro Yamada Nobuya Inagaki Yutaka Seino | 2007 | Diabetes Research and Clinical Practice2007，，3： | 2 |
| 5 | Hepatectomy simulation discrepancy between radionuclide receptor imaging and CT volumetry: influence of decreased unilateral portal venous flow显示文摘 | Shiro Akaki Yoshihiro Okumura Nobuya Sasai Shuhei Sato Masatoshi Tsunoda Masahiro Kuroda Susumu Kanazawa Yoshio Hiraki | 2003 | Annals of Nuclear Medicine2003，，1： | 2 |
| 6 | Endoscopic submucosal dissection for cancers of the remnant stomach after distal gastrectomy显示文摘 | Ryuta Takenaka Yoshiro Kawahara Hiroyuki Okada Takao Tsuzuki Satoru Yagi Jun Kato Nobuya Ohara Tadashi Yoshino Atsushi Imagawa Shigeatsu Fujiki Rie Takata Masahiro Nakagawa Motowo Mizuno Tomoki Inaba Tatsuya Toyokawa Kohsaku Sakaguchi | 2008 | Gastrointestinal Endoscopy2008，，2： | 2 |
| 7 | A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings显示文摘Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue. | Katsuyoshi Tamaki Ichiro Shimizu Mari Urata Nao Kohno Hiroshi Fukuno Susumu Ito Nobuya Sano | 2007 | World Journal of Gastroenterology2007，13，19： | 2 |
| 8 | Characteristics of DPOAE audiogram in tinnitus patients显示文摘 | Yosaku Shiomi Jun Tsuji Yasushi Naito Nobuya Fujiki Norio Yamamoto | 1997 | Hearing Research1997，，1： | 1 |
| 9 | Effects of some chinese spices on body weights,plasma lipids,lipid peroxides,and glucose,and liver lipids in mice显示文摘 | YU L Q NOBUYA S HIRAMITSU S | 2007 | Food Sci Technol Res2007，13，2： | 1 |
| 10 | Forecasting system of irri- gation water on paddy field by fuzzy theory显示文摘 | Nobuya Saruwatari Atsushi Yomota | 1995 | Agricultural Wa- ter Managemen1995，68，： | 1 |
| 11 | Increased Incidence of Follicular Lymphoma in the Duodenum显示文摘 | Tadashi Yoshino Kenji Miyake Koichi Ichimura Tomohiko Mannami Nobuya Ohara Shuji Hamazaki Tadaatsu Akagi | 2000 | The American Journal of Surgical Pathology2000，，5： | 1 |
| 12 | Glutamine and arginine metabolism in tumor-bearing rats receiving total parenteral nutrition显示文摘 | Shogo Yoshida Nobuya Ishibashi Toshihiro Noake Yuichirou Shirouzu Toshinori Oka Kazuo Shirouzu | 1997 | Metabolism1997，，4： | 1 |
| 13 | Salicylic acid induces extracellar superoxide generation followed by an increase in cytosolic calcium ion in tobacco suspension culture:the earliest events in salicylic acid signal transductioin显示文摘 | Kawano T Nobuya S Takahashi S | 1999 | Plant Cell Physiology1999，39，7： | 1 |
| 14 | Higher expression of chemokine receptor CXCR7 is linked to early and metastatic rccurrence in pathological stage I non-small cell lung cancer显示文摘 | Shotaro I Nobuya M | 2009 | Cancer2009，9，16： | 1 |
| 15 | Development of introgression lines of an Indica-type rice variety, IR64, for unique agronomic traits and detection of the responsible chromosomal regions显示文摘 | Daisuke Fujita Rizza E. Santos Leodegario A. Ebron Mary J. Telebanco-Yanoria Hiroshi Kato Sohei Kobayashi Yusaku Uga Etsuko Araki Toshiyuki Takai Hiroshi Tsunematsu Tokio Imbe Gurdev S. Khush Darshan S. Brar Yoshimichi Fukuta Nobuya Kobayashi | 2009 | Field Crops Research2009，，2： | 1 |
| 16 | A Note on Credit Risk of Vertical Keiretsu Firms: Preliminary Evidence from the Japanese Automobile Industry显示文摘 | Naoya Takezawa Nobuya Takezawa | 2005 | Asia-Pacific Financial Markets2005，，4： | 1 |
| 17 | Stress Increases Plasma Enzyme Activity in Rats: Differential Effects of Adrenergic and Cholinergic Blockades显示文摘 | Hiroyuki Arakawa Hiroshi Kodama Nobuya Matsuoka | 1997 | J Pharmacol Exp Ther1997，280，3： | 1 |
| 18 | Solidification and abrasion wear of white cast irons alloyed with 20% carbide forming elements显示文摘 | YASUHIRO Matsubara NOBUYA Sasaguri KAZUMICHI Shimizu | 2001 | Wear2001，250，： | 1 |
| 19 | Science parks in Japan and their value-added contributions to new technology-based firms显示文摘 | Nobuya F | 2006 | Internati- onal Journal of Industrial Organization2006，，24： | 1 |
| 20 | Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization显示文摘 | Shin‐ichiro Kiyose Kiyoko Nagura Hong Tao Hisaki Igarashi Hidetaka Yamada Masanori Goto Matsuyoshi Maeda Nobuya Kurabe Masaya Suzuki Masaru Tsuboi Tomoaki Kahyo Kazuya Shinmura Naohiko Hattori Haruhiko Sugimura | 2012 | Pathology International2012，，7： | 1 |
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