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| 1 | Prognosis following transcatheter arterial embolization for 121 patients with unresectable hepatocellular carcinoma with or without a history of treatment显示文摘瞄准:回顾地为 HCC 后面的 transcatheter 与肝细胞癌(HCC ) 评估病人的预后与或没有治疗的历史动脉的 embolization (TAE ) 。方法:有在我们的医院里从 1992 ~ 2004 与 TAE 对待的 HCC 的 121 个病人在这研究被注册。84 个病人为 HCC 有治疗的历史,当时 37。在入口,有额外肝的转移的病人,门静脉肿瘤血栓,或孩子呸班的时候, C 被排除。当 HCC 的复发被提高的肿瘤标记,或 ultrasonography 或动态计算断层摄影术调查结果诊断时, TAE 被重复。结果:肿瘤尺寸更大,没有过去的治疗(P<0.01 ) ,肿瘤的数字是在病人的少数。然而,在节点转移(TNM ) 舞台或幸存在 2 个组之间评估的肿瘤没有差别。一个双性人 alpha-fetoprotein (法新社)(>100 ng/mL ) 的小叶片的肿瘤和高水平是与在有 HCC 的历史的病人的差的预后有关的因素。结论:预后追随者 TAE 在有或没有过去的治疗的 HCC 病人之间是类似的。在到一堂重复 TAE 功课的入口能改进预后以前, HCC 或周期性的 HCC 和获得的好本地人的早诊断对 HCC 控制。 | Atsushi Hiraoka Teru Kumagi Masashi Hirooka Takahide Uehara Kiyotaka Kurose Hidehito luchi Yoichi Hiasa Bunzo Matsuura Kojiro Michitaka Seishi Kumano Hiroaki Tanaka Yoshimasa Yamashita Norio Horiike Teruhito Mochizuki Morikazu Onji | 2006 | World Journal of Gastroenterology2006，12，13： | 9 |
| 2 | Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma显示文摘AIM To elucidate the effect of expression of doublecortin and Ca M kinase-like-1(DCLK1) in patients with pancreatic ductal adenocarcinoma(PDAC). METHODS Tumor specimens were obtained from 136 patients with pancreatic cancer who had undergone resection without preoperative therapy between January 2000 and December 2013 at the Department of Surgical Oncology, Osaka City University. The resected specimens were analyzed for associations with clinicopathological data, including DCLK1 expression, epithelial mesenchymal transition(EMT) marker expression, and cancer stem cell(CSC) marker expression. Univariate and multivariate survival analyses were performed and we assessed the association between DCLK1 expression and clinicopathological factors, including the EMT marker and CSC marker.RESULTS In total, 48.5%(66/136) of the pancreatic cancer samples were positive for DCLK1. Patients with DCLK1-positive tumors had significantly shorter survival times than those with DCLK1-negative tumors(median, 18.7 mo vs 49.5 mo, respectively; P < 0.0001). Positive DCLK1 expression correlated with histological grade(P = 0.0290), preoperative CA19-9 level(P = 0.0060), epithelial cell adhesion molecule(Ep CAM) expression(P = 0.0235), and the triple-positive expression of CD44/CD24/Ep CAM(P = 0.0139). On univariate survival analysis, five factors were significantly associated with worse overall survival: histological grade of G2 to G4(P = 0.0091), high preoperative serum SPan-1 level(P = 0.0034), R1/2(P < 0.0001), positive expression of DCLK1(P < 0.0001) or CD44(P = 0.0245). On multivariate survival analysis, R1/2 [odds ratio(OR) = 2.019, 95% confidence interval(CI): 1.380-2.933; P = 0.0004] and positive DCLK1 expression(OR = 1.848, 95%CI: 1.2854-2.661; P = 0.0009) were independent prognostic factors. CONCLUSION DCLK1 expression was found to be an independent prognostic factor and it may play a crucial prognostic role by promoting acquisition of stemness. | Kohei Nishio Kenjiro Kimura Ryosuke Amano Bunzo Nakata Sadaaki Yamazoe Go Ohira Kotaro Miura Naoki Kametani Hiroaki Tanaka Kazuya Muguruma Kosei Hirakawa Masaichi Ohira | 2017 | World Journal of Gastroenterology2017，23，31： | 3 |
| 3 | Vitamin D receptor expression is associated with colon cancer in ulcerativecolitis显示文摘 | Koji Wada Hiroaki Tanaka Kiyoshi Maeda Toru Inoue Eiji Noda Ryosuke Amano Naoshi Kubo Kazuya Muguruma Nobuya Yamada Masakazu Yashiro Tetsuji Sawada Bunzo Nakata Masaichi Ohira Kosei Hirakawa | 2009 | Oncology Reports2009，，5： | 2 |
| 4 | Participation of adrenomedullin and its relation with vascular endothelial growth factorin androgen regulation of prostatic blood flow in vivo显示文摘 | Yasuhiro S Bunzo K Seiji A | | 0，，05： | 1 |
| 5 | Diagnostic usefulness of FDG PET for pancreatic mass lesions显示文摘 | Koichi Koyama Terue Okamura Joji Kawabe Bunzo Nakata Kosei Hirakawa-Y. S. Chung Hironobu Ochi Ryusaku Yamada | 2001 | Annals of Nuclear Medicine2001，，3： | 1 |
| 6 | Non‐alcoholic fatty liver disease: Factors associated with its presence and onset显示文摘 | Teruki Miyake Teru Kumagi Shinya Furukawa Yoshio Tokumoto Masashi Hirooka Masanori Abe Yoichi Hiasa Bunzo Matsuura Morikazu Onji | 2013 | J Gastroenterol Hepatol2013，，： | 1 |
| 7 | Cloing of a human dopamine D4 receptor gene with high affinity for the antipsychotic clozapine 显示文摘 | Van Tol HH Bunzoe JR Guan HC | 1991 | Nature1991，，： | 1 |
| 8 | Crystal Structure of Glycoside Hydrolase Family 78 α- L -Rhamnosidase from Bacillus sp. GL1显示文摘 | Zhongli Cui Yukie Maruyama Bunzo Mikami Wataru Hashimoto Kousaku Murata | 2007 | Journal of Molecular Biology2007，，2： | 1 |
| 9 | Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract显示文摘 | Eiji Takeshita Bunzo Matsuura Maoqing Dong Laurence J. Miller Hidetaka Matsui Morikazu Onji | 2006 | Journal of Gastroenterology2006，，3： | 1 |
| 10 | Dietary habits and nutrient intake in non-alcoholic steatohepatitis显示文摘 | Kumiko Toshimitsu Bunzo Matsuura Ikuko Ohkubo Tetsuji Niiya Shinya Furukawa Yoichi Hiasa Mieko Kawamura Kiyoshi Ebihara Morikazu Onji | 2007 | Nutrition2007，，1： | 1 |
| 11 | Crystal Structure of Pullulanase: Evidence for Parallel Binding of Oligosaccharides in the Active Site显示文摘 | Bunzo Mikami Hiroyuki Iwamoto Dominggus Malle Hye-Jin Yoon Elif Demirkan-Sarikaya Yoshihiro Mezaki Yoshio Katsuya | 2006 | Journal of Molecular Biology2006，，3： | 1 |
| 12 | Molecular Design of Seed Storage Proteins for Enhanced Food Physicochemical Properties显示文摘 | Mary Rose G. Tandang-Silvas Evelyn Mae Tecson-Mendoza Bunzo Mikami Shigeru Utsumi Nobuyuki Maruyama | 2011 | Annual Review of Food Science and Technology2011，，： | 1 |
| 13 | α-Amylase from B. amyloliquefaciens : purification, characterization, raw starch degradation and expression in E. coli显示文摘 | Elif Sarikaya Demirkan Bunzo Mikami Motoyasu Adachi Takahiko Higasa Shigeru Utsumi | 2004 | Process Biochemistry2004，，8： | 1 |
| 14 | Recent clinical features of Wilson’s disease with hepatic presentation显示文摘 | Teru Kumagi Norio Horiike Kojiro Michitaka Aki Hasebe Keiko Kawai Yoshio Tokumoto Seiji Nakanishi Shinya Furukawa Yoichi Hiasa Hidetaka Matsui Kiyotaka Kurose Bunzo Matsuura Morikazu Onji | 2004 | Journal of Gastroenterology2004，，12： | 1 |
| 15 | On the corrosion resistance of plasma-sprayed ceramic coats in neutral solution显示文摘 | BUNZO T SUNAO M NOBUYA I | | 0，，01： | 1 |
| 16 | Chemokine receptor CCR7 expression correlates with lymph node metastasis in pancreatic cancer显示文摘 | Bunzo Nakata | 2008 | Clinical translation research2008，78，： | 1 |
| 17 | Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease显示文摘 | Teruki Miyake Sheikh Mohammad Fazle Akbar Osamu Yoshida Shiyi Chen Yoichi Hiasa Bunzo Matsuura Masanori Abe Morikazu Onji | 2010 | Journal of Gastroenterology2010，，8： | 1 |
| 18 | Change in the crystal packing of soybean β-amylase mutants substit uted at a few surface amino acid residue显示文摘 | YOU-NA KANG MOTOYASU ADACHI BUNZO MIKAMI | 2003 | Protein Engineering2003，16，11： | 1 |
| 19 | Dietary habits and nutrient intake in non-alcoholic steatohepatitis显示文摘 | Kumiko Toshimitsu Bunzo Matsuura Ikuko Ohkubo Tetsuji Niiya Shinya Furukawa Yoichi Hiasa Mieko Kawamura Kiyoshi Ebihara Morikazu Onji | 2007 | Nutrition2007，，： | 1 |
| 20 | Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract显示文摘 | Eiji T Bunzo M Maoqing D | 2006 | J Gastroenterol2006，41，3： | 1 |
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