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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Production of laccase by Coriolus versicolor and its application in decolorization of dyestuffs: (Ⅱ) Decolorization of dyes by laccase containing fermentation broth with or without self-immobilized mycelia显示文摘The capability of decolorization for commercial dyes by Coriolus versicolor fermentation broth containing laccase with or without immobilized mycelium was evaluated. With cell free fermentation broth containing laccase, high decolorization ratio was achieved for acid orange 7, but not for the other dyes concerned. The immobilized mycelium was proved to be more efficient than the cell free system. All the four dyestuffs studied were found being decolourized with certain extent by immobilized mycelium. The repeated batch decolorization was carried out with satisfactory results. The experimental data showed that the continuous decolorization of wastewater from a printing and dyeing industry was possible by using the self immobilized C. Versicolor. | LIN Jian ping, LIAN Wei, XIA Li ming, CEN Pei lin\+* (Department of Chemical Engineering and Bioengineering, Zhejiang University, Hangzhou 310027, China. | 2003 | Journal of Environmental Sciences2003，15，1： | 7 |
| 3 | Effectiveness and Safety of a Novel Approach for Management of Patients with Potential Difficult Mask Ventilation and Tracheal Intubation: A Multi-center Randomized Trial显示文摘 | Ji-Ming Wang Er-Li Ma Qing-Ping Wu Ming Tian Yan-Yan Sun Jing Lin Liang Peng Qiang Xu Wei Wei Hong Tan Cen Yang Xiao-Qiang Li Yun-Xia Zuo Jin Liu | 2018 | Chinese Medical Journal2018，，6： | 3 |
| 4 | Differentially Expressed microRNAs as Potential Markers for Vital Reaction of Burned Skin显示文摘The identification of antemortem burns and postmortem burns is essential in forensic practice.In this study,microRNA(miRNA)microarray analysis was conducted to identify differentially expressed miRNAs in the skin of an experimental burn model.Microarray analysis revealed 24 differentially expressed miRNAs in antemortem burned mice skin,with 19 miRNAs significantly upregulated and 5 downregulated.Based on the intersection predicted using three databases(Targetscan,microRNA.org,and PITA),293 potential miRNA targets were identified.These dysregulated miRNAs and their predicted targets were further analyzed using the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases.Several functional categories and signaling pathways were enriched,including the“fc epsilon ri signaling pathway,”“endometrial cancer,”and“mTOR signaling pathway.”Expression patterns of 10 differentially expressed miRNAs were verified by reverse transcription‑quantitative polymerase chain reaction in mice skins.The results agreed with the results of microarray analysis.These findings suggest that differentially expressed miRNAs revealed by microarray are potential markers for forensic molecular diagnosis of antemortem burns. | Hao‑Pin Lyu Ming Cheng Jin‑Cen Liu Ming‑Yuan Ye Di Xu Jie‑Tao He Xiao‑Li Xie Qi Wang | 2018 | Journal of Forensic Science and Medicine2018，4，3： | 2 |
| 5 | Modeling and Generating Realistic Background Traffic by Hybrid Approach显示文摘One of the key challenges in largescale network simulation is the huge computation demand in fine-grained traffic simulation.Apart from using high-performance computing facilities and parallelism techniques,an alternative is to replace the background traffic by simplified abstract models such as fluid flows.This paper suggests a hybrid modeling approach for background traffic,which combines ON/OFF model with TCP activities.The ON/OFF model is to characterize the application activities,and the ordinary differential equations(ODEs) based on fluid flows is to describe the TCP congestion avoidance functionality.The apparent merits of this approach are(1) to accurately capture the traffic self-similarity at source level,(2) properly reflect the network dynamics,and(3) efficiently decrease the computational complexity.The experimental results show that the approach perfectly makes a proper trade-off between accuracy and complexity in background traffic simulation. | QIAN Yaguan GUAN Xiaohui JIANG Ming CEN Gang | 2015 | China Communications2015，12，10： | 2 |
| 6 | Synthesis and characterization of a sensitive and selective Fe^(3+) fluorescent sensor based on novel sulfonated calix[4]arene-based host-guest complex显示文摘A novel fluorescent sensor was prepared from sulfonated calix[4]arene(SC4A)by the host-guest com-plexation method using the fluorescent dye rhodamine B(RB)as a structure-directing agent.The crystal structure of the host-guest complex(RB@(SC4A)_(3))was confirmed by X-ray diffraction studies while its performance and sensing mechanism for metal ion pollutants were characterized using fluorescence and nuclear magnetic resonance spectroscopies.The results showed that RB@(SC4A)_(3) had a triangular branch structure resulting from host-guest mediation of the interactions between the three SC4A host molecules and the three terminal groups of the guest molecule RB.The host-guest complex exhibited sensitive and selective sensing towards Fe^(3+)ions via a fluorescence quenching mechanism.The results indicated that RB@(SC4A)_(3) could be a promising sensitive and selective fluorescent sensor for metal ion pollutants mon-itoring.It also provided new insights into the synthesis of calixarene-based host-guest complex. | Ran Cen Ming Liu Jihong Lu Weifang Zhang Jingjing Dai Xi Zeng Zhu Tao Xin Xiao | 2022 | Chinese Chemical Letters2022，33，5： | 2 |
| 7 | OPC(OLE for Process Control)based Calibration System for Embedded Controller显示文摘 | Cen Ming Liu Qian Yan Yi | 2012 | Journal of Software2012，7，12： | 1 |
| 8 | Olfactory Dysfunction in Parkinson's Disease Patients with the LRRK2 G2385R Variant显示文摘Olfactory dysfunction has been reported in Parkinson's disease(PD) patients carrying the LRRK2G2019 S variant in Caucasians but rarely in those with die LRRK2 G2385 R variant.In this study,we performed genotyping for the LRRK2 G2385 R variant in PD patients recruited from the Movement Disorder Clinic of Xuanwu Hospital in Beijing and in healthy controls randomly selected from the Beijing Longitudinal Study on Aging cohort.The 'five-odor olfactory detection array',an olfactory threshold test,was used to assess olfactory function.One hundred and eighty-six participants were enrolled,comprising 43 PD patients without(iPD) and 25with(LRRK2-PD) the LRRK2 G2385 R variant,and 118 healthy controls.Our results showed mat the threshold of olfactory identification was significantly worse in PD patients than in controls,but not significantly different between me iPD and LRRK2-PD groups.These findings suggested that although olfactory function in LRRK2-PD patients is impaired,it is similar to that in iPD patients. | Ming Cao Zhu-Qin Gu Yuan Li Hui Zhang Xiao-Juan Dan Shan-Shan Cen Da-Wei Li Piu Chan | 2016 | Neuroscience Bulletin2016，32，6： | 1 |
| 9 | Clinical diagnosis of severe COVID-19:A derivation and validation of a prediction rule显示文摘BACKGROUND The widespread coronavirus disease 2019(COVID-19)has led to high morbidity and mortality.Therefore,early risk identification of critically ill patients remains crucial.AIM To develop predictive rules at the time of admission to identify COVID-19 patients who might require intensive care unit(ICU)care.METHODS This retrospective study included a total of 361 patients with confirmed COVID-19 by reverse transcription-polymerase chain reaction between January 19,2020,and March 14,2020 in Shenzhen Third People’s Hospital.Multivariate logistic regression was applied to develop the predictive model.The performance of the predictive model was externally validated and evaluated based on a dataset involving 126 patients from the Wuhan Asia General Hospital between December 2019 and March 2020,by area under the receiver operating curve(AUROC),goodness-of-fit and the performance matrix including the sensitivity,specificity,and precision.A nomogram was also used to visualize the model.RESULTS Among the patients in the derivation and validation datasets,38 and 9 participants(10.5%and 2.54%,respectively)developed severe COVID-19,respectively.In univariate analysis,21 parameters such as age,sex(male),smoker,body mass index(BMI),time from onset to admission(>5 d),asthenia,dry cough,expectoration,shortness of breath,asthenia,and Rox index<18(pulse oxygen saturation,SpO2)/(FiO2×respiratory rate,RR)showed positive correlations with severe COVID-19.In multivariate logistic regression analysis,only six parameters including BMI[odds ratio(OR)3.939;95%confidence interval(CI):1.409-11.015;P=0.009],time from onset to admission(≥5 d)(OR 7.107;95%CI:1.449-34.849;P=0.016),fever(OR 6.794;95%CI:1.401-32.951;P=0.017),Charlson index(OR 2.917;95%CI:1.279-6.654;P=0.011),PaO2/FiO2 ratio(OR 17.570;95%CI:1.117-276.383;P=0.041),and neutrophil/lymphocyte ratio(OR 3.574;95%CI:1.048-12.191;P=0.042)were found to be independent predictors of COVID-19.These factors were found to be significant risk factors for severe patients confirmed with COVID-19.The AUROC was 0.941(95%CI:0.901-0.981)and 0.936(95%CI:0.886-0.987)in both datasets.The calibration properties were good.CONCLUSION The proposed predictive model had great potential in severity prediction of COVID-19 in the ICU.It assisted the ICU clinicians in making timely decisions for the target population. | Ming Tang Xia-Xia Yu Jia Huang Jun-Ling Gao Fu-Lan Cen Qi Xiao Shou-Zhi Fu Yang Yang Bo Xiong Yong-Jun Pan Ying-Xia Liu Yong-Wen Feng Jin-Xiu Li Yong Liu | 2021 | World Journal of Clinical Cases2021，9，13： | 1 |
| 10 | Optoelectronic parametric oscillator显示文摘Oscillators are one of the key elements in various applications as a signal source to generate periodic oscillations.Among them,an optical parametric oscillator(OPO)is a driven harmonic oscillator based on parametric frequency conversion in an optical cavity,which has been widely investigated as a coherent light source with an extremely wide wavelength tuning range.However,steady oscillation in an OPO is confined by the cavity delay,which leads to difficulty in frequency tuning,and the frequency tuning is discrete with the minimum tuning step determined by the cavity delay.Here,we propose and demonstrate a counterpart of an OPO in the optoelectronic domain,i.e.,an optoelectronic parametric oscillator(OEPO)based on parametric frequency conversion in an optoelectronic cavity to generate microwave signals.Owing to the unique energy-transition process in the optoelectronic cavity,the phase evolution in the OEPO is not linear,leading to steady single-mode oscillation or multimode oscillation that is not bounded by the cavity delay.Furthermore,the multimode oscillation in the OEPO is stable and easy to realize owing to the phase control of the parametric frequency-conversion process in the optoelectronic cavity,while stable multimode oscillation is difficult to achieve in conventional oscillators such as an optoelectronic oscillator(OEO)or an OPO due to the mode-hopping and mode-competition effect.The proposed OEPO has great potential in applications such as microwave signal generation,oscillator-based computation,and radio-frequency phase-stable transfer. | Tengfei Hao Qizhuang Cen Shanhong Guan Wei Li Yitang Dai Ninghua Zhu Ming Li | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 11 | An Application of Necessary and sufficient condition of C-equivalence 显示文摘 | Cen Yan ming | 1989 | Journal of Mathematical Research and Exposition1989，，： | 1 |
| 12 | Inhibition of the Crystal Growth and Aggregation of Calcium Oxalate by Algae Sulfated Polysaccharide In-vitro显示文摘The influence of sulfated polysaccharide (SPS) isolated from marine algae Sargassum fusiforme on the morphology and phase compositions of urinary crystal calcium oxalate was investigated in vitro by means of scanning electron microscopy and X-ray diffraction. SPS maybe is a potential inhibitor to CaOxa urinary stones by inhibiting the growth of calcium oxalate monohydrate (COM), preventing the aggregation of COM, and inducing the formation of calcium oxalate dihydrate (COD) crystals. | Xiu Mei WU Jian Ming OUYANG Sui Ping DENG Ying Zhou CEN | 2006 | Chinese Chemical Letters2006，17，1： | 1 |
| 13 | Production of laccase by Coriolus versicolor and its application in decolorization of dyestuffs: (Ⅰ) Production of laccase by batch and repeated-batch processes显示文摘The production of laccase by Coriolus versicolor was studied. The effect of cultivation conditions on laccase production by Coriolus versicolor was examined to obtain optimal medium and cultivation conditions. Both batch and repeated batch processes were performed for laccase production. In repeated batch fermentation with self immobilized mycelia, total of 14 cycles were performed with laccase activity in the range between 3.4 and 14.8 U/ml. | LIN Jian ping, LIAN Wei, XIA Li ming, CEN Pei lin\+* (Department of Chemical Engineering and Bioengineering, Zhejiang University, Hangzhou 310027, China. | 2003 | Journal of Environmental Sciences2003，15，1： | 1 |
| 14 | Association of Thyroid Nodules with Various Elements in Urine and Blood Serum: A Case-Control Study显示文摘Thyroid nodules are a common clinical problem caused by various factors,including environmental and nutritional factors and genetic background.The environment can modulate and influence not only the risk of thyroid nodules but also the severity of disease in humans[1].The environment is awash with elements,and all mineral elements,including heavy metals and trace elements,are considered potentially toxic.A significantly higher incidence of thyroid cancer has been reported in populations exposed to low doses of metallic elements in volcanic areas over a long period[2].As research on thyroid disorders continues,it is becoming clear that abnormalities in trace elements in the body can affect the development of thyroid-related disorders. | LI Xiang Zhi WU Cai Lian CEN Li Ting HUANG Ming Le HUANG Min Min QIU Mei Ting LU Xiao Ling | 2024 | Biomedical and Environmental Sciences2024，37，3： | 0 |
| 15 | Large-scale coherent Ising machine based on optoelectronic parametric oscillator显示文摘Ising machines based on analog systems have the potential to accelerate the solution of ubiquitous combinatorial optimization problems.Although some artificial spins to support large-scale Ising machines have been reported,e.g.,superconducting qubits in quantum annealers and short optical pulses in coherent Ising machines,the spin stability is fragile due to the ultra-low equivalent temperature or optical phase sensitivity.In this paper,we propose to use short microwave pulses generated from an optoelectronic parametric oscillator as the spins to implement a large-scale Ising machine with high stability.The proposed machine supports 25,600 spins and can operate continuously and stably for hours.Moreover,the proposed Ising machine is highly compatible with high-speed electronic devices for programmability,paving a low-cost,accurate,and easy-to-implement way toward solving real-world optimization problems. | Qizhuang Cen Hao Ding Tengfei Hao Shanhong Guan Zhiqiang Qin Jiaming Lyu Wei Li Ninghua Zhu Kun Xu Yitang Dai Ming Li | 2022 | Light(Science & Applications)2022，11，12： | 0 |
| 16 | Observation of parity-time symmetry in time-division multiplexing pulsed optoelectronic oscillators within a single resonator显示文摘In recent years,parity-time(PT)symmetry in optoelectronic systems has been widely studied,due to its potential applications in lasers,sensors,topological networks,and other fields.In this paper,a time-division multiplexed pulsed optoelectronic oscillator(OEO)is proposed to study the dynamics of a PT symmetry system.Two microwave pulses are used to realize the PT symmetry in a single spatial resonator based on the temporal degrees of freedom.The gain and loss of the microwave pulses and the coupling coefficient between them can then be controlled.We first demonstrate the phase diagram from PT broken to PT symmetry in the OEO system.We theoretically prove that the perturbation of a coupling-induced phase shift larger than(2π)×10^(-2)causes the disappearance of the PT symmetry.In this experiment,the perturbation is less than(2π)×0.5×10^(-2);thus,the phase transition of PT symmetry is observed.In addition,multipairs of PT-symmetry pulses indicate that pulsed OEO could be used to implement complex non-Hermitian Hamilton systems.Therefore,it is confirmed that pulsed OEO is an excellent platform to explore the dynamics of PT symmetry and other non-Hermitian Hamiltonian systems. | HAO DING QIZHUANG CEN KUN XU MING LI YITANG DAI | 2022 | Photonics Research2022，10，8： | 0 |
| 17 | Comparison and development of advanced machine learning tools to predict nonalcoholic fatty liver disease:An extended study显示文摘Background:Nonalcoholic fatty liver disease(NAFLD)is a public health challenge and significant cause of morbidity and mortality worldwide.Early identification is crucial for disease intervention.We recently proposed a nomogram-based NAFLD prediction model from a large population cohort.We aimed to explore machine learning tools in predicting NAFLD.Methods:A retrospective cross-sectional study was performed on 15315 Chinese subjects(10373 training and 4942 testing sets).Selected clinical and biochemical factors were evaluated by different types of machine learning algorithms to develop and validate seven predictive models.Nine evaluation indicators including area under the receiver operating characteristic curve(AUROC),area under the precision-recall curve(AUPRC),accuracy,positive predictive value,sensitivity,F1 score,Matthews correlation coefficient(MCC),specificity and negative prognostic value were applied to compare the performance among the models.The selected clinical and biochemical factors were ranked according to the importance in prediction ability.Results:Totally 4018/10373(38.74%)and 1860/4942(37.64%)subjects had ultrasound-proven NAFLD in the training and testing sets,respectively.Seven machine learning based models were developed and demonstrated good performance in predicting NAFLD.Among these models,the XGBoost model revealed the highest AUROC(0.873),AUPRC(0.810),accuracy(0.795),positive predictive value(0.806),F1 score(0.695),MCC(0.557),specificity(0.909),demonstrating the best prediction ability among the built models.Body mass index was the most valuable indicator to predict NAFLD according to the feature ranking scores.Conclusions:The XGBoost model has the best overall prediction ability for diagnosing NAFLD.The novel machine learning tools provide considerable beneficial potential in NAFLD screening. | Yuan-Xing Liu Xi Liu Chao Cen Xin Li Ji-Min Liu Zhao-Yan Ming Song-Feng Yu Xiao-Feng Tang Lin Zhou Jun Yu Ke-Jie Huang Shu-Sen Zheng | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，5： | 0 |
| 18 | Error-space estimate method for generalized synergic target tracking显示文摘To improve the tracking accuracy and stability of an optic-electronic target tracking system,the concept of generalized synergic target and an algorithm named error-space estimate method is presented.In this algorithm,the motion of target is described by guide data and guide errors,and then the maneuver of the target is separated into guide data and guide errors to reduce the maneuver level.Then state estimate is implemented in target state-space and error-space respectively,and the prediction data of target position are acquired by synthesizing the filtering data from target state-space according to kinematic model and the prediction data from errorspace according to guide error model.Differing from typical multi-model method,the kinematic and guide error models work concurrently rather than switch between models.Experiment results show that the performance of the algorithm is better than Kalman filter and strong tracking filter at the same maneuver level. | Ming CEN Chengyu FU Ke CHEN Xingfa LIU | 2009 | Frontiers of Electrical and Electronic Engineering in China2009，4，1： | 0 |
| 19 | The role of AFAP1-AS1 in mitotic catastrophe and metastasis of triple-negative breast cancer cells by activating the PLK1 signaling pathway显示文摘Triple-negative breast cancer(TNBC)is characterized by fast growth,high metastasis,high invasion,and a lack of therapeutic targets.Mitosis and metastasis of TNBC cells are two important biological behaviors in TNBC malignant progression.It is well known that the long noncoding RNA AFAP1-AS1 plays a crucial role in various tumors,but whether AFAP1-AS1 is involved in the mitosis of TNBC cells remains unknown.In this study,we investigated the functional mechanism of AFAP1-AS1 in targeting Polo-like Kinase 1(PLK1)activation and participating in mitosis of TNBC cells.We detected the expression of AFAP1-AS1 in the TNBC patient cohort and primary cells by in situ hybridization(ISH),northern blot,fluorescent in situ hybridization(FISH)and cell nucleus/cytoplasm RNA fraction isolation.High AFAP1-AS1 expression was negatively correlated with overall survival(OS),disease-free survival(DFS),metastasis-free survival(MFS)and recurrence-free survival(RFS)in TNBC patients.We explored the function of AFAP1-AS1 by transwell,apoptosis,immunofluorescence(IF)and patient-derived xenograft(PDX)models in vitro and in vivo.We found that AFAP1-AS1 promoted TNBC primary cell survival by inhibiting mitotic catastrophe and increased TNBC primary cell growth,migration and invasion.Mechanistically,AFAP1-AS1 activated phosphorylation of the mitosis-associated kinase PLK1 protein.Elevated levels of AFAP1-AS1 in TNBC primary cells increased PLK1 pathway downstream gene expression,such as CDC25C,CDK1,BUB1 and TTK.More importantly,AFAP1-AS1 increased lung metastases in a mouse metastasis model.Taken together,AFAP1-AS1 functions as an oncogene that activates the PLK1 signaling pathway.AFAP1-AS1 could be used as a potential prognostic marker and therapeutic target for TNBC. | SHUIZHONG CEN XIAOJIE PENG JIANWEN DENG HAIYUN JIN ZHINAN DENG XIAOHUA LIN DI ZHU MING JIN YANWEN ZHU PUSHENG ZHANG YUNFENG LUO HONGYAN HUANG | 2023 | Oncology Research2023，31，3： | 0 |
| 20 | Double-cavity nor-seco-cucurbit[10]uril-based supramolecular assembly for selective detection and removal of trinitrophenol显示文摘The effective removal and selective detection of explosive and toxic pollutant trinitrophenol (TNP) is an attractive but challenging field.Herein,a double-cavity nor-seco-cucurbit[10]uril (ns-Q[10])-based supramolecular assembly 8-HQ@ns-Q[10]was fabricated and its structure was characterized by X-ray single crystal diffraction.In this assembly,the stoichiometric ratio of ns-Q[10]and 8-hydroxyquinoline (8-HQ) is 1:2,which is also attributed to the special double-cavity structure of ns-Q[10].The luminescence sensing experiments showed that 8-HQ@ns-Q[10]can be used as a good fluorescence-enhanced sensing material (enhanced 27-fold) for the rapid detection of explosives and the aqueous contaminant TNP,with a limit of detection (LOD) of 2.07×10^(-5)mol/L,without interference from other phenolic compounds.Furthermore,TNP can be efficiently removed in the presence of assembly 8-HQ@ns-Q[10],and the removal efficiency is more than 89%.Therefore,the supramolecular assembly 8-HQ@ns-Q[10],as a fluorescenceenhanced luminescence sensor and adsorption material,has rich research value and potential application prospect when applied to the detection and removal of TNP in aqueous environment. | Ran Cen Ming Liu Jiao He Dingwu Pan Lixia Chen Ying Huang Zhu Tao Xin Xiao | 2023 | Chinese Chemical Letters2023，34，10： | 0 |
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