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| 1 | Endocytoscopic narrow-band imaging efficiency for evaluation of inflammatory activity in ulcerative colitis显示文摘AIM:To assess the efficacy of endocytoscopic narrowband imaging(EC-NBI)for evaluating the severity of inflammation in ulcerative colitis(UC).METHODS:This retrospective study was conducted at a single tertiary care referral center.We included UC patients who underwent colonoscopy with endocytoscopy from July 2010 to December 2013.ECNBI was performed,and the images were evaluated by assessing visibility,increased vascularization,and the increased calibers of capillaries and were classified as Obscure,Visible or Dilated.Obscure was indicative of inactive disease,while Visible and Dilated were indicative of acute inflammation.This study received Institutional Review Board approval.The primary outcome measures included the diagnostic ability of EC-NBI to distinguish between active and inactive UC on the basis of histological activity.The conventional endoscopic images were classified according to the Mayo endoscopic score.A score of 0 or 1 indicated inactive disease,whereas a score of 2 indicated active disease.RESULTS:Fifty-two patients were enrolled.There was a strong correlation between the EC-NBI findings and the histological assessment(r=0.871,P<0.01).The sensitivity,specificity,positive predictive value,negative predictive value,and accuracy of EC-NBI for diagnosing acute inflammation were 84.0%,100%,87.1%,100%,and 92.3%,respectively,while those for the Mayo endoscopic score were 100%,40.7%,100%,61.0%,and 69.2%,respectively.Compared with conventional endoscopy,EC-NBI was superior in diagnostic specificity,negative predictive value,and accuracy(P<0.001,P=0.001 and P=0.047,respectively).CONCLUSION:The EC-NBI finding of capillaries in the rectal mucosa was strongly correlated with histological inflammation and aided in the differential diagnosis between active and inactive UC. | Yasuharu Maeda Kazuo Ohtsuka Shin-ei Kudo Kunihiko Wakamura Yuichi Mori Noriyuki Ogata Yoshiki Wada Masashi Misawa Akihiro Yamauchi Seiko Hayashi Toyoki Kudo Takemasa Hayashi Hideyuki Miyachi Fuyuhiko Yamamura Fumio Ishida Haruhiro Inoue Shigeharu Hamatani | 2015 | World Journal of Gastroenterology2015，21，7： | 4 |
| 2 | Efficiency of endocytoscopy in differentiating types of serrated polyps显示文摘 | Makoto Kutsukawa Shin-ei Kudo Nobunao Ikehara Yushi Ogawa Kunihiko Wakamura Yuichi Mori Katsuro Ichimasa Masashi Misawa Toyoki Kudo Yoshiki Wada Takemasa Hayashi Hideyuki Miyachi Haruhiro Inoue Shigeharu Hamatani | 2014 | Gastrointestinal Endoscopy2014，，4： | 3 |
| 3 | Consumption of n-3 Fatty Acids and Fish Reduces Risk of Hepatocellular Carcinoma显示文摘 | Norie Sawada Manami Inoue Motoki Iwasaki Shizuka Sasazuki Taichi Shimazu Taiki Yamaji Ribeka Takachi Yasuhito Tanaka Masashi Mizokami Shoichiro Tsugane | 2012 | Gastroenterology2012，，7： | 2 |
| 4 | Myocardial perfusion and fatty acid metabolism in patients with tako-tsubo-like left ventricular dysfunction显示文摘 | Satoshi Kurisu Ichiro Inoue Takuji Kawagoe Masaharu Ishihara Yuji Shimatani Kenji Nishioka Takashi Umemura Suji Nakamura Masashi Yoshida Hikaru Sato | 2003 | Journal of the American College of Cardiology2003，，： | 2 |
| 5 | Isolated ileal perforation due to cytomegalovirus reactivation during management of terbinafine hypersensitivity显示文摘We report a case of 71-year-old man who developed a hypersensitivity syndrome associated with terbinafine. He was placed on terbinafine (250 mg/d) for the treatment of tinea pedis due to diabetes mellitus. Following the treatment with terbinafine, he developed druginduced hypersensitivity syndrome (DIHS). Systemic corticosteroid led to transient improvement of his clinical manifestations. Three months after disease onset, he presented with panperitonitis due to ileal perforation, and underwent an emergency operation. The affected ileum was resected and ileostomy was performed in the terminal ileum. Cytomegalovirus (CMV)-specific IgG antibodies were significantly increased, high-titer CMV antigenemia was detected, and pathological examination of the resected ileum confirmed CMV infection. Based onthese observations, we strongly recommend that physicians monitor reactivation of the family of herpesvirus other than herpesvirus 6, to manage DIHS properly. | Soichi Sano Hiroki Ueno Keiko Yamagami Yosuke Yakushiji Yoshihiro Isaka Isao Kawasaki Masashi Takemura Takeshi Inoue Masayuki Hosoi | 2010 | World Journal of Gastroenterology2010，16，26： | 2 |
| 6 | Autothermal reforming of methane over Ni catalysts supported over CaO/CeO2/ZrO2 solid solution显示文摘 | Tatsuya Takeguchi Shin-Nosuke Furukawa Masashi Inoue | 2003 | Applied Catalysis A:General2003，240，： | 1 |
| 7 | Synthesis of yttrium alumina garnet by the hydrothermal method显示文摘 | MASASHI Inoue HIROYUKI Otsu HIROSHI Kominami | 1991 | J Am Cerarn Soc1991，74，： | 1 |
| 8 | Monitoring and mathematical modeling of mitochondrial ATP in myotubes at single-cell level reveals two distinct population with different kinetics显示文摘Backgrounds ATP is the major energy source for myotube contraction,and is quickly produced to compensate ATP consumption and to maintain sufficient ATP level.ATP is consumed mainly in cytoplasm and produced in mitochondria during myotube contraction.To understand the mechanism of ATP homeostasis during myotube contraction,it is essential to monitor mitochondrial ATP at single-cell level,and examine how ATP is produced and consumed in mitochondria.Methods:We established C2C12 cell line stably expressing fluorescent probe of mitochondrial ATP,and induced differentiation into myotubes・We gave electric pulse stimulation to the differentiated myotubes,and measured mitochondrial ATP.We constructed mathematical model of mitochondrial ATP at single-cell level,and analyzed kinetic parameters of ATP production and consumption.Results:We performed hierarchical clustering analysis of time course of mitochondrial ATP,which resulted in two clusters.Cluster 1 showed strong transient increase,whereas cluster 2 showed weak transient increase.Mathematical modeling at single-cell level revealed that the ATP production rate of cluster 1 was larger than that of cluster 2,and that both regulatory pathways of ATP production and consumption of cluster 1 were faster than those of cluster 2.Cluster 1 showed larger mitochondrial mass than cluster 2,suggesting that cluster 1 shows the similar property of slow muscle fibers,and cluster 2 shows the similar property of fast muscle fibers.Conclusions Cluster 1 showed the stronger mitochondrial ATP increase by larger ATP production rate,but not smaller consumption.Cluster 1 might reflect the larger oxidative capacity of slow muscle fiber. | Naoki Matsuda Ken-ichi Hironaka Masashi Fujii Takumi Wada Katsuyuki Kunida Haruki Inoue Miki Eto Daisuke Hoshino Yasuro Furuichi Yasuko Manabe Nobuharu LFujii Hiroyuki Noji Hiromi Imamura Shinya Kuroda | 2020 | Quantitative Biology2020，8，3： | 1 |
| 9 | Local Release of C-Reactive Protein From Vulnerable Plaque or Coronary Arterial Wall Injured by Stenting显示文摘 | Teruo Inoue Toru Kato Toshihiko Uchida Masashi Sakuma Atsuko Nakajima Mitsuei Shibazaki Yoshitaka Imoto Masahiko Saito Shigemasa Hashimoto Yutaka Hikichi Koichi Node | 2005 | Journal of the American College of Cardiology2005，，2： | 1 |
| 10 | Marked promotive effect of iron on visible-light-induced photocatalytic activities of Nitrogen-and Silicon-Codoped Titanias显示文摘 | Hirotaka Ozaki Shinji Iwamoto Masashi Inoue | 2007 | J Phys Chem C2007，111，17： | 1 |
| 11 | Linkage of Familial Moyamoya Disease (Spontaneous Occlusion of the Circle of Willis) to Chromosome 17q25显示文摘 | Tohru Yamauchi Mitsuhiro Tada Kiyohiro Houkin Toshihiro Tanaka Yusuke Nakamura Satoshi Kuroda Hiroshi Abe Takuya Inoue Kiyonobu Ikezaki Toshio Matsushima Masashi Fukui | 2000 | Stroke: Journal of the American Heart Association2000，，： | 1 |
| 12 | Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts显示文摘 | Hiroshi Takayanagi Sunhwa Kim Takako Koga Hiroshi Nishina Masashi Isshiki Hiroki Yoshida Akio Saiura Miho Isobe Taeko Yokochi Jun-ichiro Inoue Erwin F. Wagner Tak W. Mak Tatsuhiko Kodama Tadatsugu Taniguchi | 2002 | Developmental Cell2002，，6： | 1 |
| 13 | Branched chain amino acids enhance the maturation and function of myeloid dendritic cells ex vivo in patients with advanced cirrhosis显示文摘 | Eiji Kakazu Yoshiyuki Ueno Yasuteru Kondo Koji Fukushima Masaaki Shiina Jun Inoue Keiichi Tamai Masashi Ninomiya Tooru Shimosegawa | 2009 | Hepatology2009，，6： | 1 |
| 14 | Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model显示文摘 | Munetaka Suzuki Gen Inoue Takefumi Gemba Tomoko Watanabe Toshinori Ito Takana Koshi Kazuyo Yamauchi Masaomi Yamashita Sumihisa Orita Yawara Eguchi Nobuyasu Ochiai Shunji Kishida Masashi Takaso Yasuchika Aoki Kazuhisa Takahashi Seiji Ohtori | 2009 | European Spine Journal2009，，： | 1 |
| 15 | Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts显示文摘 | Kazuki Nabeshima Yoshiya Shimao Teruhiko Inoue Masashi Koono | 2002 | Cancer Letters2002，，1： | 1 |
| 16 | Oral administration of royal jelly inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice显示文摘 | Yoshifumi Taniguchi Keizo Kohno Shin-ichiro Inoue Satomi Koya-Miyata Iwao Okamoto Norie Arai Kanso Iwaki Masao Ikeda Masashi Kurimoto | 2003 | International Immunopharmacology2003，，9： | 1 |
| 17 | Surgical Versus Nonsurgical Treatment of Selected Patients With Discogenic Low Back Pain: A Small-Sized Randomized Trial显示文摘 | Seiji Ohtori Takana Koshi Masaomi Yamashita Kazuyo Yamauchi Gen Inoue Munetaka Suzuki Sumihisa Orita Yawara Eguchi Nobuyasu Ochiai Shunji Kishida Masashi Takaso Kazuki Kuniyoshi Yasuchika Aoki Tetsuhiro Ishikawa Gen Arai Masayuki Miyagi Hiroto Kamoda Miya | 2011 | Spine2011，，5： | 1 |
| 18 | Impact of acute hyperglycemia on left ventricular function after reperfusion therapy in patients with a first anterior wall acute myocardial infarction显示文摘 | Masaharu Ishihara Ichiro Inoue Takuji Kawagoe Yuji Shimatani Satoshi Kurisu Kenji Nishioka Takashi Umemura Shuji Nakamura Masashi Yoshida | 2003 | American Heart Journal2003，，4： | 1 |
| 19 | Synthesis course of the Ni-SAPO-34 catalyst for methanol-to-olefin conversion 显示文摘 | Masashi Inoue Pongtorn Dhupatemiya Suphot Phatanasri | 1999 | Microporous and Mesoporous Materials1999，28，1： | 1 |
| 20 | 显示文摘 | Hirotaka Ozaki Shinji Jwamoto Masashi Inoue | 2007 | Phys Chem C2007，111，17： | 1 |
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