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| 1 | Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBDs) are chronic disorders of modern society, requiring management strategies aimed at prolonging an active life and establishing the exact etiology and pathogenesis.These idiopathic diseases have environmental, genetic,immunologic, inflammatory, and oxidative stress components. On the one hand, recent advances have shown that abnormal immune reactions against the microorganisms of the intestinal flora are responsible for the inflammation in genetically susceptible individuals. On the other hand, in addition to T helper cell-type(Th) 1 and Th2 immune responses,other subsets of T cells, namely regulatory T cells and Th17 maintained by IL-23 are likely to develop IBD. IL-23 acts on innate immune system members and also facilitates the expansion and maintenance of Th17 cells. The IL-17/IL-23 axis is relevant in IBD pathogenesis both in human and experimental studies. Novel biomarkers of IBD could be calprotectin,microRNAs, and serum proinflammatory cytokines.An efficient strategy for IBD therapy is represented by the combination of IL-17 A and IL-17 F in acute IL-17 A knockout TNBS-induced colitis, and also definite decrease of the inflammatory process in IL-17 F knockout, DSS-induced colitis have been observed.Studying the correlation between innate and adaptive immune systems, we hope to obtain a focused reviewin order to facilitate future approaches aimed at elucidating the immunological mechanisms that control gut inflammation. | Cristina-Sorina Cǎanǎ Ioana Berindan Neagoe Vasile Cozma Cristian Magdas Flaviu Tǎbǎan Dan Lucian Dumitrasu | 2015 | World Journal of Gastroenterology2015，21，19： | 37 |
| 2 | 查看详情显示文摘 | Zhang J Chu T S Dong S L Yuan S P Fu A E Dan Y B | | 0，，： | 1 |
| 3 | Mandated data archiving greatly improves access to research data 显示文摘 | Vines T H Andrew R I」 Dan G B | 2013 | FasebJournal2013，27，4： | 1 |
| 4 | An analysis of generalized slotted-Aloha protocols 显示文摘 | RICHARD T B M VISHAL M DAN R | 2009 | IEEE/ACM Transactions on Networ- king2009，17，3： | 1 |
| 5 | Shapley mappings and the cumulative value for n-person games with fuzzy coalitions显示文摘 | Dan B Kroupa T | 2008 | European Journal of Operational Research2008，186，： | 1 |
| 6 | Comparison of intensity-mod- ulated radiotherapy, adaptive radiotherapy, proton radiotherapy, and adaptive proton radiotherapy for treatment of locally advanced head and neck cancer显示文摘 | Simone C B Ly D Dan T D | 2011 | Radiother Oneol2011，101，3： | 1 |
| 7 | Retrofitting from solvent based to waterborne PSAs 显示文摘 | Beth W M Scott W S Dan T B | 1995 | Adhesives Age1995，11，： | 1 |
| 8 | Industry differences in the production of audit services显示文摘 | Michael T Steins Dan A Simunic Terrence B O'Keefe | 1994 | Auditing: A Journal of Practice and Theory1994，13，： | 1 |
| 9 | Comparison of intensity- modulated radiotherapy, adaptive radiotherapy proton radiotherapy, and adaptive proton radiotherapy for treatment of locally advanced head and neck cancer 显示文摘 | Simone C B 2nd Ly D Dan T D | 2011 | Radiother Oncol2011，101，3： | 1 |
| 10 | Use of Lactobacillus probiotics for bacterial geni- tourinary infections in women: A review 显示文摘 | Robert B Dan T | 2008 | Clinical Therapeutics2008，30，3： | 1 |
| 11 | Industry differences in the production of audit services 显示文摘 | Stein Michael T Simunic Dan A O Keefe Terrence B | 1987 | Auditing: A Journal of Practice and Theory1987，，13： | 1 |
| 12 | One-dimensional conducting polymer nanostructures: bulk synthesis and applications 显示文摘 | HENRY D T DAN LI RICHARD B K | 2009 | Adv Mater2009，21，1415： | 1 |
| 13 | Genome sequence of the palaeopolyp|oid soybean 显示文摘 | Jeremy S Steven B C Jessica S Ma J X Therese M William N David L H Qijian S Jay J T Cheng J L Xu D Uffe H Gregory D M Yeisoo Y Tetsuya S Taishi U Madan K B Devinder S Babu V Erika L Myron P David G Shu S Q David G Kerrie B Montona F Brian A Du J C Tian Z Zhu L Navdeep G Trupti J Marc L Anand S Zhang X C Kazuo S Henry T N Rod A Perry C James S Jane G Dan R Gary S Randy C S Scott A J | 2010 | Nature2010，463，： | 1 |
| 14 | 查看详情显示文摘 | Huang X B Yang L B Li J Zhou S T Ren X D Zhang S Q Dan J K Cai H C Duan S C Chen G H Zhang Z W Ouyang K Li J Zhang Z H Zhou R G Wang G L | | 0，，： | 1 |
| 15 | Collective response from a cationic tetrahedral fluorene for label-free DNA detection 显示文摘 | Liu B Dan T T T Bazan G C | 2007 | Adv Funct Mater2007，17，14： | 1 |
| 16 | Theoretical analysis of binaural multimicrophone noise reduction techniques显示文摘 | CORNELIS B DOCLO S VAN DAN BOGAERT T | | 0，，02： | 1 |
| 17 | Still Balancing Improvement and Accountability Developments in External Quality Assuranee in the Nordic Countries 1996-2006显示文摘 | Dan T Stensaker B | 2007 | Quality in Higher Education2007，13，1： | 1 |
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