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| 1 | Intelligent and connected vehicles: Current status and future perspectives显示文摘Intelligent connected vehicles(ICVs) are believed to change people's life in the near future by making the transportation safer,cleaner and more comfortable. Although many prototypes of ICVs have been developed to prove the concept of autonomous driving and the feasibility of improving traffic efficiency, there still exists a significant gap before achieving mass production of high-level ICVs. The objective of this study is to present an overview of both the state of the art and future perspectives of key technologies that are needed for future ICVs. It is a challenging task to review all related works and predict their future perspectives, especially for such a complex and interdisciplinary area of research. This article is organized to overview the ICV key technologies by answering three questions: what are the milestones in the history of ICVs; what are the electronic components needed for building an ICV platform; and what are the essential algorithms to enable intelligent driving? To answer the first question, the article has reviewed the history and the development milestones of ICVs. For the second question, the recent technology advances in electrical/electronic architecture, sensors, and actuators are presented. For the third question, the article focuses on the algorithms in decision making, as the perception and control algorithm are covered in the development of sensors and actuators. To achieve correct decision-making, there exist two different approaches: the principle-based approach and data-driven approach. The advantages and limitations of both approaches are explained and analyzed. Currently automotive engineers are concerned more with the vehicle platform technology, whereas the academic researchers prefer to focus on theoretical algorithms. However, only by incorporating elements from both worlds can we accelerate the production of high-level ICVs. | YANG DianGe JIANG Kun ZHAO Ding YU ChunLei CAO Zhong XIE ShiChao XIAO ZhongYang JIAO XinYu WANG SiJia ZHANG Kai | 2018 | Science China(Technological Sciences)2018，61，10： | 31 |
| 2 | Efficacy and safety evaluation of icotinib in patients with advanced non-small cell lung cancer显示文摘Objective: To evaluate the efficacy and safety of icotinib hydrochloride in patients with advanced non-small cell lung cancer (NSCLC). Methods: A total of 89 patients with stage ⅢB or IV NSCLC received icotinib at a dose of 125 mg administered 3 times a day. Icotinib treatment was continued until disease progression or development of unacceptable toxicity. Results: A total of 89 patients were assessable. In patients treated with icotinib, the overall response rate (RR) was 36.0% (32/89), and the disease control rate (DCR) was 69.7% (62/89). RR and DCR were significantly improved in patients with adenocarcinoma versus non-adenocarcinoma (P<0.05). The symptom improvement rate was 57.3% (51/89), and the main symptoms improved were cough, pain, chest distress, dyspnea, and Eastern Cooperative Oncology Group performance status. The main toxic effects were rash [30/89 (33.7%)] and diarrhea [15/89 (16.9%)]. The level of toxicity was typically low. Conclusions: The use of icotinib hydrochloride in the treatment of advanced NSCLC is efficacious and safe, and its toxic effects are tolerable. | Aiqin Gu Chunlei Shi Liwen Xiong Tianqing Chu Jun Pei Baohui Han | 2013 | Chinese Journal of Cancer Research2013，25，1： | 22 |
| 3 | Modern stalagmite oxygen isotopic composition and its implications of climatic change from a high-elevation cave in the eastern Qinghai-Tibet Plateau over the past 50 years显示文摘An oxygen isotope record of a stalagmite from Huanglong Cave in the eastern Qinghai-Tibet Plateau dated with 230Th and 210Pb methods provides variations of the Asian monsoon with an average resolu-tion of 1 year over the past 50 years. This study shows that the δ18O of dripwater in the cave represents the annual mean δ18O of local meteoric precipitation and the stalagmites were deposited in isotopic equilibrium. A comparison of the stalagmite δ18O record with instrumentally meteorological data indi-cates that shifts of the δ18O are largely controlled by the amount effect of meteoric precipitation con-veyed through the southwest monsoon(the Indian monsoon) and less affected by temperature. Therefore,the variations of δ18O record reflect the changes in monsoon precipitation on inter-annual time scales under the influence of the southwest monsoon. Like many other stalagmite δ18O records in the Asian monsoon regions,the δ18O record of the stalagmite from Huanglong Cave also reveals a gradually enriched trend during the past 50 years,i.e. relatively enriched in 18O. This trend may indicate the decline of the Asian monsoon intensity which is consistent with the decrease of monsoon indices. The weakening of the modern Asian monsoon well matched with the temperature changes in strato-sphere,which may illustrate that the weakening of the monsoon mainly results from the lowering of solar radiation. | YANG XunLin ZHANG PingZhong CHEN FaHu HUH Chih-an LI HongChun CHENG Hai Kathleen R. JOHNSON LIU JingHua AN ChunLei | 2007 | Chinese Science Bulletin2007，52，9： | 20 |
| 4 | Mechanism-based anti-anxiety effects of polysaccharides extracted from Shudihuang (Radix Rehmanniae Preparata) by two-dimensional electrophoresis analysis in rat hippocampus proteins显示文摘OBJECTIVE: To investigate mechanism-based anti-anxiety effects of Shudihuang (Radix Rehmanniae Preparata) polysaccharides (RRPPs) through two-dimensional electrophoresis (2-DE) analysis with mass spectrometry (MS) of hippocampus proteins in rats treated with monosodium L-glutamate (MSG).METHODS: MSG (4 g/kg) or normal saline (NS) was injected subcutaneously into infant male rats on days 2, 4, 6, 8, 10 after birth. MSG-treated rats at 8 weeks old were given NS, diazepam, or RRPPs daily for seven consecutive days by intragastric administration, while NS-treated rats given the same volume of NS. Elevated plus maze (EPM) and light/ dark transition (LDT) tests were used to observe anti-anxiety effects of RRPPs at 1 h after the last administration. After EPM and LDT tests, hippocampus tissues were excised on ice rapidly from the brains of rats. Thereafter, 2-DE and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) were used for detecting differential proteins in hippocampus of rats so as to explore the potential mechanisms. RESULTS: RRPPs (200, 400 mg/kg) could significantly inhibit MSG-induced decrease of time and entries percentages in open zones in EPM test and numbers of light-dark transition in LDT test. Further analysis of 2-DE and MALDI-TOF/MS indicated that β-synuclein, protein DJ-1, peroxiredoxin-2, peroxiredoxin-6, dimethylarginine dimethylaminohydrolase 1 (DDAH-1) and iron-sulfur proteins were all found to be down-regulated significantly in MSG-treated rats, while such down-regulation was significantly inhibited after treatment with RRPPs. CONCLUSION: RRPPs showed anti-anxiety effects and potential mechanisms might be related to inhibiting MSG-induced down-regulation of β-synuclein, DJ-1, peroxiredoxin-2, peroxiredoxin-6, DDAH-1 and iron-sulfur proteins in hippocampus of rats. | Ying Cui Chunlei Rong Junming Wang Can Cui Li Wang Zhiyi Feng Jing Feng Bing Niu | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 19 |
| 5 | High-speed femtosecond laser plasmonic lithography and reduction of graphene oxide for anisotropic photoresponse显示文摘Micro/nanoprocessing of graphene surfaces has attracted significant interest for both science and applications due to its effective modulation of material properties,which,however,is usually restricted by the disadvantages of the current fabrication methods.Here,by exploiting cylindrical focusing of a femtosecond laser on graphene oxide(GO)films,we successfully produce uniform subwavelength grating structures at high speed along with a simultaneous in situ photoreduction process.Strikingly,the well-defined structures feature orientations parallel to the laser polarization and significant robustness against distinct perturbations.The proposed model and simulations reveal that the structure formation is based on the transverse electric(TE)surface plasmons triggered by the gradient reduction of the GO film from its surface to the interior,which eventually results in interference intensity fringes and spatially periodic interactions.Further experiments prove that such a regular structured surface can cause enhanced optical absorption(>20%)and an anisotropic photoresponse(~0.46 ratio)for the reduced GO film.Our work not only provides new insights into understanding the laser-GO interaction but also lays a solid foundation for practical usage of femtosecond laser plasmonic lithography,with the prospect of expansion to other two-dimensional materials for novel device applications. | Tingting Zou Bo Zhao Wei Xin Ye Wang Bin Wang Xin Zheng Hongbo Xie Zhiyu Zhang Jianjun Yang Chunlei Guo | 2020 | Light(Science & Applications)2020，9，1： | 17 |
| 6 | Assessment of the relative role of climate change and human activities in desertification:显示文摘Climate change and human activities are the two kinds of driving forces in desertification,and assessing their relative role in desertification is of great significance to deeply understanding the driving mechanisms and preventing desertification expansion.This paper has systematically reviewed the progress of the researches on assessing the relative role of climate change and human activities in desertification from qualitative,semi-quantitative and quantitative aspects respectively.The authors found that there were still some problems in the previous researches.For example,the subjectivity in assessment was obvious,the assessment cannot be easily repeated,and the assessment and its results were always based on administrative regions and less taken and expressed in a continuous space.According to the progress of previous researches and the works conducted by the authors recently,we put forward a quantitative approach by selecting NPP as a common indicator to measure the relative role of climate change and human activities in desertification and dividing the ecological process of 'driving force effect-dynamic response of desertified land' into several scenarios.Meanwhile,validation and scale of assessment should be taken into account when quantitative assessment of the relative role of climate change and human activities in desertification are carried out. | XU Duanyang LI Chunlei ZHUANG Dafang PAN Jianjun | 2011 | Journal of Geographical Sciences2011，21，5： | 16 |
| 7 | Simulation of the Interaction between Driver and Seat显示文摘Test is one of methods to acquire human-seat pressure distribution in driving,with the deficiency of being uneasy to obtain the stress information of soft tissue inside human body and the sheer force of interface between human and seat,which can be obtained by simulation.But current simulation method focuses mainly on calculation itself other than combining it with posture prediction and cab packaging parameters,which cause it difficult to acquire accurate pressure calculation results without accurate posture of human body,and make it almost meaningless to design optimization.Therefore,a human body geometric model with posture change capability is built and linked up with Cascade Prediction Model(CPM),which takes cab packaging parameters as inputs.A detailed finite element model of driver human body is constructed and used to conduct the driver-seat interaction simulation between human body and seat.Good accordance of pressure distribution is observed between simulation and test,which validates the simulation.In addition to the distribution pattern,curves on key sections are used to analyze the pressure and shear stress on the seat surface,as well as soft tissue stress inside human body.The simulation shows that the maximum stress of buttocks locates under the ischial tuberosity,and the maximum stress of trunk occurs near the scapula posterior and the lower waist.These are the places where fatigue usually occurs.The maximum pressure of seat appears at the driver-seat contact area corresponding to the driver’s maximum skin tissue stress.In order to guide the seat design and cab packaging and study the influence of posture to pressure distribution,finite element models for different levels of cab packaging parameters are created by using CPM.The pressure distributions are calculated and their tendencies varying with cab packaging parameters are obtained.The method presented provides a new way to accurately simulate the interaction between driver human body and seat,and to guide the seat design and cab packaging so as to improve seating comfort. | DU Xiaoming REN Jindong SANG Chunlei LI Lemeng | 2013 | Chinese Journal of Mechanical Engineering2013，26，6： | 14 |
| 8 | High precision in-situ Pb isotopic analysis of sulfide minerals by femtosecond laser ablation multi-collector inductively coupled plasma mass spectrometry显示文摘An in-situ microanalysis of Pb isotopic compositions in sulfide minerals is carried out by using femtosecond laser-ablation multi-collector inductively coupled plasma mass spectrometry(fs LA-MC-ICP-MS).High-temperature-activated carbon was used to filter Hg contained in the carrier gas,which reduced the Hg background signal by 48%and also lowered the detection limit of the analysis.Fractionation and mass discrimination effects existing in the ICP-MS analytical processes were corrected using an internal reference Tl in conjunction with an external reference NIST SRM 610.The proposed method was used to analyze the Pb isotopic compositions of chalcopyrite,pyrite,and sphalerite from the Dulong Sn-Zn-In polymetallic ore district.The results showed that in this ore district,the sulfide minerals and different grains of the same sulfide mineral show a large variation in Pb content up to 1000-fold.The studied pyrites show relatively higher Pb contents and homogeneous Pb isotopic compositions,whereas the sphalerites have low Pb contents but most variable Pb isotopic compositions.It is suggested that the large variation of Pb isotopic composition may reflect a late hydrothermal superimposition on the primary sulfide formation.In addition,radiogenic Pb accumulated by radioactive decay of trace amounts of U over time in the host minerals may also be one of the causes for the large variation range of Pb content and Pb isotopic composition of those low-Pb sphalerites.Chalcopyrite and sphalerite grains with Pb content greater than 10 ppm presented a consistent Pb isotopic distribution,whereas all the sulfide grains with Pb content greater than 100 ppm had consistent Pb isotopic composition within 2s measurement uncertainties.The in-situ analysis of Pb isotopic composition agreed well with the results obtained by conventional chemical methods within2s measurement uncertainties,indicating that the data obtained by fs LA-MC-ICP-MS are reliable.Additionally,this study indicates that the Pb isotopic composition could truthfully record the source of ore-forming minerals only for sulfide minerals with high Pb content.On the contrary,the Pb isotopic composition of low-Pb sulfide minerals may be affected by trace amounts of U in the host minerals that may lead to a highly radiogenic Pb isotope ratio.Alternatively,it is also possible that late fluid metasomatic overprinting may alter the Pb isotopic compositions. | YUAN HongLin YIN Cong LIU Xu CHEN KaiYun BAO ZhiAn ZONG ChunLei DAI MenNing LAI ShaoCong WANG Rong JIANG ShaoYong | 2015 | Science China Earth Sciences2015，58，10： | 14 |
| 9 | Effect of temperature,salinity and irradiance on growth and photosynthesis of Ulva prolifera显示文摘Intensive Pyropia aquaculture in the coast of southwestern Yellow Sea and its subsequent waste, including disposed Ulva prolifera, was speculated to be one of the major sources for the large-scale green tide proceeding in the Yellow Sea since 2007. It was, however, unclear how the detached U. prolifera responded and resumed growing after they detached from its original habitat. In this study, we investigated the growth and photosynthetic response of the detached U. prolifera to various temperature, salinity and irradiance in the laboratory. The photosynthetic rate of the detached U. prolifera was significantly higher at moderate temperature levels(14–27°C)and high salinity(26–32), with optimum at 23°C and 32. Both low(<14°C) and highest temperature(40°C), as well as low salinity(8) had adverse effects on the photosynthesis. Compared with the other Ulva species, U. prolifera showed higher saturated irradiance and no significant photoinhibition at high irradiance, indicating the great tolerance of U. prolifera to the high irradiance. The dense branch and complex structure of floating mats could help protect the thalli and reduce photoinhibition in field. Furthermore, temperature exerted a stronger influence on the growth rate of the detached U. prolifera compared to salinity. Overall, the high growth rate of this detached U. prolifera(10.6%–16.7% d^(–1)) at a wide range of temperature(5–32°C) and salinity(14–32) implied its blooming tendency with fluctuated salinity and temperature during floating. The environmental parameters in the southwestern Yellow Sea at the beginning of green tide were coincident with the optimal conditions for the detached U. prolifera. | XIAO Jie ZHANG Xiaohong GAO Chunlei JIANG Meijie LI Ruixiang WANG Zongling LI Yan FAN Shiliang ZHANG Xuelei | 2016 | Acta Oceanologica Sinica2016，35，10： | 14 |
| 10 | Changes in cerebral hemodynamics in patients with posttraumatic diffuse brain swelling after external intraventricular drainage显示文摘 | Kefei Chen Jirong Dong Tian Xia Chunlei Zhang Wei Zhao Qinyi Xu Xuejian Cai | 2015 | Chinese Journal of Traumatology2015，18，2： | 13 |
| 11 | A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice显示文摘The transient elevation of cytoplasmic calcium is essential for pathogen-associated molecular pattern(PAMP)-triggered immunity(PTI).However,the calcium channels responsible for this process have remained unknown.Here,we show that rice CDSI(CELL DEATH and SUSCEPTIBLE to BLAST 1)encoding OsCNGC9;a cyclic nucleotide-gated channel protein,positively regulates the resistance to rice blast disease.We show that OsCNGC9 mediates PAMP-induced Ca2+influx and that this event is critical for PAMPs-triggered ROS burst and induction of PTI-related defense gene expression.We further show that a PTI related receptor-lih cytoplasmic kinase OsRLCK185 physically interacts with and phosphorylates OsCNGC9 to activate its channel activity.Our results suggest a signaling cascade linking pattern recognition to calcium channel activation,which is required for initiation of PTI and disease resistance in rice. | Jiachang Wang Xi Liu An Zhang Yulong Ren Fuqing Wu Gang Wang Yang Xu Cailin Lei Shanshan Zhu Tian Pan Yongfei Wang Huan Zhang Fan Wang Yan-Qiu Tan Yupeng Wang Xin Jin Sheng Luo Chunlei Zhou Xiao Zhang Jinling Liu Shuai Wang Lingzhi Meng Yihua Wang Xi Chen Qibing Lin Xin Zhang Xiuping Guo Zhijun Cheng Jiulin Wang Yunlu Tian Shijia Liu Ling Jiang Chuanyin Wu Ertao Wang Jian-Min Zhou Yong-Fei Wang Haiyang Wang Jianmin Wan | 2019 | Cell Research2019，29，10： | 13 |
| 12 | Asian summer monsoon precipitation recorded by stalagmite oxygen isotopic composition in the western Loess Plateau during AD1875―2003 and its linkage with ocean-atmosphere system显示文摘Based on 5 high-precision 230Th dates and 103 stable oxygen isotope ratios (δ18O) obtained from the top 16 mm of a stalagmite collected from Wanxiang Cave,Wudu,Gansu,variation of monsoonal precipita-tion in the modern Asian Monsoon (AM) marginal zone over the past 100 years was reconstructed. Comparison of the speleothem δ18O record with instrumental precipitation data at Wudu in the past 50 years indicates a high parallelism between the two curves,suggesting that the speleothem δ18O is a good proxy for the AM strength and associated precipitation,controlled by 'amount effect' of the pre-cipitation. Variation of the monsoonal precipitation during the past 100 years can be divided into three stages,increasing from AD 1875 to 1900,then decreasing from AD 1901 to 1946,and increasing again thereafter. This variation is quite similar to that of the Drought/Flooding index archived from Chinese historical documents. This speleothem-derived AM record shows a close association with the Pacific Decadal Oscillation (PDO) between AD 1875 and 1977,with higher monsoonal precipitation corre-sponding to cold PDO phase and vice versa at decadal timescale. The monsoonal precipitation varia-tion is out of phase with the PDO after AD 1977,probably resulting from the decadal climate jump in the north Pacific occurring at around AD 1976/77. These results demonstrate a strong linkage between the AM and associated precipitation and the Pacific Ocean via ocean/atmosphere interaction. This rela-tionship will aid to forecast future hydrological cycle for the AM monsoon region,and to improve forecasting potential of climatic model with observation data from cave. | LIU JingHua ZHANG PingZhong CHENG Hai CHEN FaHu YANG XunLin ZHANG DeZhong ZHOU Jing JIA JiHong AN ChunLei SANG WenCui Kathleen R. JOHNSON | 2008 | Chinese Science Bulletin2008，53，13： | 13 |
| 13 | Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma显示文摘很少长期的发炎怎么贡献 hepatocellular 癌(HCC ) 的前进被知道,特别癌症的开始。揭开从长期的发炎的批评转变到在网络水平的 HCC 和分子的机制,我们用我们的动态网络 biomarker (DNB ) 分析了土拨鼠肝炎 virus/c-myc 鼠标和匹配年龄的 wt-C57BL/6 鼠标的时间系列 proteomic 数据模型。DNB 分析显示在转基因的老鼠的出生以后的第 5 月是癌症开始的批评时期,就在批评转变前,它与临床的症状一致。同时,联系 DNB 的网络在批评转变前后显示出蛋白质表示和 coexpression 层次的激烈的倒置。DNB, PLA2G6 和 CYP2C44 的二个成员,与他们的联系差别一起表示了蛋白质,被发现导致 arachidonic 酸新陈代谢的机能障碍,进一步通过短暂受体潜力隧道的煽动性的调停人规定激活煽动性的回答,并且最后导致肝 detoxification 和恶意的转变的缺陷到癌症。作为一个 c-Myc 目标, PLA2G6 断然在表示与 c-Myc 相关,显示出从减少到在 carcinogenesis 期间增加的一个趋势,与在批评转变的最小的点或付小费给的点。相应 PLA2G6 和 c-Myc 的如此的趋势也在人的 hepatocarcinogenesis 期间被观察,与在高级 dysplastic 小瘤(就在 carcinogenesis 前的一个阶段) 的最小的点。我们的学习暗示 PLA2G6 可能在 hepatocarcinogenesis 期间作为象著名 c-Myc 一样的 oncogene 工作,当 PLA2G6 和 c-Myc 的 downregulation 能是显示逼近的 carcinogenesis 的一个警告信号时。 | Meiyi Li Chen Li Wei-Xin Liu Conghui Liu Jingru Cui Qingrun Li Hong Ni Yingcheng Yang Chaochao Wu Chunlei Chen Xing Zhen Tao Zeng Mujun zhao Lei Chen Jiarui Wu Rong Zeng Luonan Chen | 2017 | Journal of Molecular Cell Biology2017，9，6： | 12 |
| 14 | Spatial variability of soil water content and related factors across the Hexi Corridor of China显示文摘Soil water content(SWC) is a key factor limiting ecosystem sustainability in arid and semi-arid areas of the Hexi Corridor of China, which is characterized by an ecological environment that is vulnerable to climate change. However, there is a knowledge gap regarding the large-scale spatial distribution of SWC in this region. The specific objectives of this study were to determine the spatial distribution patterns of SWC across the Hexi Corridor and identify the factors responsible for spatial variation of SWC at a regional scale. This study collected and analyzed SWC in the 0–100 cm soil profile from 109 field sampling sites(farmland, grassland and forestland) across the Hexi Corridor in 2017. We selected 17 factors, including land use, topography(latitude, longitude, elevation, slope gradient, and slope aspect), soil properties(soil clay content, soil silt content, soil bulk density, saturated hydraulic conductivity, field capacity, and soil organic carbon content), climate factors(mean annual precipitation, potential evaporation, and aridity index), plant characteristic(vegetation coverage) and planting pattern(irrigation or rain-fed), as possible environmental variables to analyze their effects on SWC. The results showed that SWC was 0.083(±0.067) g/g in the 0–100 cm soil profile and decreased in the order of farmland, grassland and forestland. The SWC in the upper soil layers(0–20, 20–40 and 40–60 cm) had obvious difference when the mean annual precipitation differed by 200 mm. The SWC decreased from southeast to northwest following the same pattern as precipitation, and had a moderate to strong spatial dependence in a large effective range(75–378 km). The SWC showed a similar distribution and had no significant difference between soil layers in the 0–100 cm soil profile. The principal component analysis showed that the mean annual precipitation, geographical position(longitude and latitude) and soil properties(soil bulk density and soil clay content) were the main factors dominating the variance of environmental variables. A stepwise linear regression equation showed that plant characteristic(vegetation coverage) and soil properties(soil organic carbon content, field capacity and soil clay content) were the optimal factors to predict the variation of SWC. Soil clay content could be better to explain the SWC variation in the deeper soil layers compared with the other factors. | LI Xiangdong SHAO Ming'an ZHAO Chunlei JIA Xiaoxu | 2019 | Journal of Arid Land2019，11，1： | 12 |
| 15 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 16 | Capability of evolutionary cryptosystems against differential cryptanalysis显示文摘The evolutionary cryptosystem is a new cryptosystem.This paper studies its security level resisting against differential cryptanalysis.It is shown that the evolutionary cryptosystem possesses higher resistance than its initial fixed cryptosystem against differential cryptanalysis.On the basis of the relationship among the data complexity,the bit advantage and the success rate of differential cryptanalysis,it is proven that more data is needed for attacking the evolutionary cryptosystem when the bit advantage and success rate are identical.Moreover,it is shown that the time complexity for attacking the evolutionary cryptosystem is higher than that of differential attacking its initial fixed cryptosystem with the same amount of plaintext-ciphertext pairs.The research indicates that the evolutionary cryptosystem is more robust than its initial fixed cryptosystem against differential cryptanalysis. | ZHANG HuanGuo 1,2 ,LI ChunLei 1,2 & TANG Ming 1,2 1 School of Computer,Wuhan University,Wuhan 430072,China 2 Key Laboratory of Aerospace Information Security and Trusted Computing of Ministry of Education,Wuhan University,Wuhan 430072,China | 2011 | Science China(Information Sciences)2011，54，10： | 11 |
| 17 | Joint land-sea seismic survey and research on the deep structures of the Bohai Sea areas显示文摘This paper presents the survey and research work of two land-sea profiles in the Bohai Sea,China,carried out in 2010–2011,including the seismic sources on land and in the sea,the ocean bottom seismographs(OBS)and their recovery,the coupling of OBS and the environment noise in sea area,the data quality of OBSs,and the result of data analysis.We focused on the investigation of crustal structures revealed by the two NE\EW-trending joint land-sea profiles.In combination with the Pn-velocity distribution and gravitymagnetic inversion results in the North China Craton,we propose that the undulation of the Moho interface in the Bohai and surrounding areas is not strong,and the lithospheric thinning is mainly caused by the thinning of its mantle part.The research result indicates that obvious lateral variations of Moho depth and seismic velocity appear nearby all the large-scale faults in Bohai Sea,and there is evidence of underplating and reforming of the lower crust by mantle material in the Bohai area.However,geophysical evidence does not appear to support the'mantle plume'or'delamination'model for the North China Craton destruction.The crustal structure of the Bohai Sea revealed'a relatively normal crust and obviously thinned mantle lid',local velocity anomalies and instability phenomena in the crust.These features may represent a combined effect of North China-Yangtze collision at an early stage and the remote action of Pacific plate subduction at a late stage. | HAO Tianyao YOU Qingyu LIU Lihua LV Chuanchuan XU Ya LI Zhiwei ZHAO Chunlei ZHENG Yanpeng LIU Chenguang HAN Guozhong | 2013 | Acta Oceanologica Sinica2013，32，12： | 11 |
| 18 | Nanopore-based Fourth-generation DNA Sequencing Technology显示文摘Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than $1000, and possibly for even less than $100. The single-molecule techniques used by this technology allow us to further study the interaction between DNA and protein, as well as between protein and protein.Nanopore analysis opens a new door to molecular biology investigation at the single-molecule scale.In this article, we have reviewed academic achievements in nanopore technology from the past as well as the latest advances, including both biological and solid-state nanopores, and discussed their recent and potential applications. | Yanxiao Feng Yuechuan Zhang Cuifeng Ying Deqiang Wang Chunlei Du | 2015 | Genomics, Proteomics & Bioinformatics2015，13，1： | 11 |
| 19 | Performance and mechanism of Cr(Ⅵ)removal by zero-valent iron loaded onto expanded graphite显示文摘Zero-valent iron(ZⅥ) was loaded on expanded graphite(EG) to produce a composite material(EG-ZⅥ) for efficient removal of hexavalent chromium(Cr(Ⅵ)). EG and EG-ZⅥ were characterized by X-ray diffraction(XRD), scanning electron microscopy(SEM),Fourier-transform infrared(FTIR) spectroscopy and Brunauer–Emmett–Teller(BET) analysis. EG-ZⅥ had a high specific surface area and contained sub-micron sized particles of zero-valent iron. Batch experiments were employed to evaluate the Cr(Ⅵ) removal performance. The results showed that the Cr(Ⅵ) removal rate was 98.80% for EG-ZⅥ,which was higher than that for both EG(10.00%) and ZⅥ(29.80%). Furthermore, the removal rate of Cr(Ⅵ) by EG-ZⅥ showed little dependence on solution p H within a p H range of 1–9.Even at pH 11, a Cr(Ⅵ) removal rate of 62.44% was obtained after reaction for 1 hr. EG-ZⅥ could enhance the removal of Cr(Ⅵ) via chemical reduction and physical adsorption,respectively. X-ray photoelectron spectroscopy(XPS) was used to analyze the mechanisms of Cr(Ⅵ) removal, which indicated that the ZⅥ loaded on the surface was oxidized, and the removed Cr(Ⅵ) was immobilized via the formation of Cr(III) hydroxide and Cr(III)–Fe(III)hydroxide/oxyhydroxide on the surface of EG-ZⅥ. | Congbin Xu Wenjie Yang Weijiang Liu Hongliang Sun Chunlei Jiao Ai-jun Lin | 2018 | Journal of Environmental Sciences2018，30，5： | 10 |
| 20 | Transcriptional activation and phosphorylation of OsCNGC9 confer enhanced chilling tolerance in rice显示文摘Low temperature is a major environmental factor that limits plant growth and productivity.Although transient elevation of cytoplasmic calcium has long been recognized as a critical signal for plant cold tolerance,the calcium channels responsible for this process have remained largely elusive.Here we report that OsCNGC9,a cyclic nucleotide-gated channel,positively regulates chilling tolerance by mediating cytoplasmic calcium elevation in rice(Oryza sativa).We showed that the loss-of-function mutant of OsCNGC9 is defective in cold-induced calcium influx and more sensitive to prolonged cold treatment,whereas OsCNGC9 overexpression confers enhanced cold tolerance.Mechanistically,we demonstrated that in response to chilling stress,OsSAPK8,a homolog of Arabidopsis thaliana OST1,phosphorylates and activates OsCNGC9 to trigger Ca2+influx.Moreover,we found that the transcription of OsCNGC9 is activated by a rice dehydration-responsive element-binding transcription factor,OsDREB1A.Taken together,our results suggest that OsCNGC9 enhances chilling tolerance in rice through regulating cold-induced calcium influx and cytoplasmic calcium elevation. | Jiachang Wang Yulong Ren Xi Liu Sheng Luo Xiao Zhang Xin Liu Qibing Lin Shanshan Zhu Hua Wan Yang Yang Yu Zhang Bin Lei Chunlei Zhou Tian Pan Yongfei Wang Mingming Wu Ruonan jing Yang Xu Meng Han Fuqing Wu Cailin Lei Xiuping Guo Zhijun Cheng Xiaoming Zheng Yihua Wang Zhigang Zhao Ling Jiang Xin Zhang Yong-Fei Wang Haiyang Wang Jianmin Wan | 2021 | Molecular Plant2021，14，2： | 10 |
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