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| 1 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 2 | Comparative effect of electroacupuncture and moxibustion on the expression of substance P and vasoactive intestinal peptide in patients with irritable bowel syndrome显示文摘OBJECTIVE: To compare the impacts of electroacupuncture(EA) and moxibustion(Mox) on the primary gastrointestinal symptoms and the expressions of colonic mucosa-associated neuropeptide substance P(SP) and vasoactive intestinal peptide(VIP)in patients with either diarrhea-predominant or constipation-predominant irritable bowel syndrome(IBS-D and IBS-C,respectively).METHODS: Eighty-five IBS patients were randomly allocated to the EA and Mox groups. Zusanli(ST 36)and Shangjuxu(ST 37) were selected as acupoints for electroacupuncture or warm moxibustion treatment once a day for 14 consecutive days. Before and after the treatment sessions,a Visual Analog Pain Scale and the Bristol Stool Form Scale were used to evaluate gastrointestinal symptoms. There were four dropout cases,leaving 81 participants(41 with IBS-D and 40 with IBS-C) who volunteered to undergo colonoscopy before and after the treatment sessions. During colonoscopy,sigmoid mucosa were collected to detect SP and VIP expression using immunohistochemistry assay.RESULTS: Both EA and Mox treatments were effective at relieving abdominal pain in IBS-D and IBS-C patients. However,Mox was more effective at reducing diarrhea in IBS-D patients,whereas EA was more effective at improving constipation in IBS-C patients. EA and Mox treatments both down-regulated the abnormally increased SP and VIP expression in the colonic mucosa,with no significant difference shown between the two treatments.CONCLUSION: Both EA and Mox treatments are effective at ameliorating gastrointestinal symptoms by reducing SP and VIP expression in the colonic mucosa of IBS patients. | Lu Zhenzhong Yin Xiaojun Teng Weijun Chen Yuehua Sun Jie Zhao Jimeng Wang Anqi Bao Chunhui Shi Yin | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 24 |
| 3 | Geographical characteristics of China’s wetlands derived from remotely sensed data显示文摘In this paper, we report the first wetland mapping of the entire China using Landsat enhanced thematic mapper plus (ETM+) data. These data were obtained from the Global Land Cover Facility at the University of Maryland spanning from 1999 to 2002. A total of 597 scenes of Landsat images were georeferenced and mosaiced. Manual image interpretation of satellite images was aided with elevation data, soil data, land cover/land use data and Google Earth. The minimum mapping unit is 10 pixel × 10 pixel, equivalent to 9 ha. The aim of our first round of mapping was only targeted at the boundary delineation of any type of wetland except those wetlands that are under agricultural use (i.e., paddy fields), which has already been well mapped by others. Our interpretation results indicate that a total of 359478 km2 of wetlands are of non-agricultural use. Among our preliminarily mapped wetland, 339353 km2 are inland wetland, 2786 km2 are non-agricultural artificial wetland, and 17609 km2 are coastal wetland. Because low-tide is rarely captured in satellite images, an under-estimation of coastal wetland is inevitable. We conducted some statistics based on our mapped wetlands and compared them with those previously obtained from a number of sources including a land cover/land use map made with satellite images during the late 1990s and early 2000s, a marshland map developed in approximately the same period, survey data of coastal wetland in early 1980s, and area data for approximately 400 larger patches of marshland in China compiled in 1996. Because some inconsistencies exist in the guidelines of those different wetland surveys, difference in area is expected. Some further comparison indicates that the wetland distributions derived from the preliminary wetland map are reasonable and more objective than other sources. The mapping process also indicated that the method adopted by us was efficient and cost-effective. We also found that in order to ensure comparability of the wetland maps developed at different times, a set of standard guidelines on the wetland categories to be mapped, and the mapping methods to be used must be well conceived, developed and effectively employed. We carried out some initial geographical analysis on the distribution of wetlands. | NIU ZhenGuo GONG Peng CHENG Xiao GUO JianHong WANG Lin HUANG HuaBing SHEN ShaoQing WU YunZhao WANG XiaoFeng WANG XianWei YING Qing LIANG Lu ZHANG LiNa WANG Lei YAO Qian YANG ZhenZhong GUO ZiQi DAI YongJiu | 2009 | Science China Earth Sciences2009，52，6： | 15 |
| 4 | Liquefaction macrophenomena in the great Wenchuan earthquake显示文摘On May 12,2008 at 14:28,a catastrophic magnitude Ms 8.0 earthquake struck the Sichuan Province of China.The epicenter was located at Wenchuan(31.00oN,103.40oE).Liquefaction macrophenomena and corresponding destruction was observed throughout a vast area of 500 km long and 200 km wide following the earthquake.This paper illustrates the geographic distribution of the liquefaction and the relationship between liquefaction behavior and seismic intensity,and summarizes the liquefaction macrophenomena,including sandboils and waterspouts,ground subsidence,ground fi ssures etc.,and relevant liquefaction features.A brief summary of the structural damage caused by liquefaction is presented and discussed.Based on comparisons with liquefaction phenomena observed in the 1976 Tangshan and 1975 Haicheng earthquakes,preliminary analyses were performed,which revealed some new features of liquefaction behavior and associated issues arising from this event.The site investigation indicated that the spatial non-uniformity of liquefaction distribution was obvious and most of the liquefi ed sites were located in regions of seismic intensity VIII.However,liquefaction phenomena at ten different sites in regions of seismic intensity VI were also observed for the fi rst time in China mainland.Sandboils and waterspouts ranged from centimeters to tens of meters,with most between 1 m to 3 m.Dramatically high water/sand ejections,e.g.,more than 10 m,were observed at four different sites.The sand ejections included silty sand,fi ne sand,medium sand,course sand and gravel,but the ejected sand amount was less than that in the 1976 Tangshan earthquake.Possible liquefaction of natural gravel soils was observed for the fi rst time in China mainland. | Chen Longwei Yuan Xiaoming Cao Zhenzhong Hou Longqing Sun Rui Dong Lin Wang Weiming Meng Fanchao Chen Hongjuan | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 14 |
| 5 | Effect of spinal manipulation on degenerative scoliosis显示文摘OBJECTIVE:To investigate the effect of spinal manipulation(SM)on degenerative scoliosis by evaluating patients’visual analog scale(VAS)scores,Cobb angles,sagittal vertical axis(SVA),and apical vertebral rotation(AVR)and to explore factors that influence treatment effect.METHODS:A total of 55 patients with degenerative scoliosis received 4 weeks of SM.After treatment,patients were divided into two groups:the remission group(VAS score<40 mm)and the non-remission group(VAS score≥40 mm).Pre-versus post-treatment VAS scores,Cobb angles,SVA,and AVR were compared in each group and in the total population.Baseline data(sex,age,symptom characteristics,duration of symptoms,VAS score,Cobb angle,SVA,and AVR)were compared between groups.Factors influencing the post-treatment VAS score were explored with multiple linear regression analysis.RESULTS:No changes were found in the Cobb angle(P=0.722)or AVR(P=0.424)after intervention in the overall population.However,the SVA(P<0.001)and VAS score(P=0.000)changed significantly after treatment.Similar changes were observed in the remission group(n=29).Multiple linear regression revealed that the only factors influencing treatment effect were symptom characteristics,SVA,and VAS score.CONCLUSION:SM relieved pain and improved sagittal imbalance in patients with degenerative scoliosis.It did not lessen the severity of coronal curvature or vertebral rotation.Factors influencing the effect of SM included symptom characteristics,VAS score,and SVA.A larger randomized trial is needed to further confirm our results. | Sun Wu Gao Jinghua Zhu Liguo Wang Baojian Xiao Wei Wang Zhenzhong Yang Kexin | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 8 |
| 6 | Wheat powdery mildew resistance gene Pm64 derived from wild emmer (Triticum turgidum var.dicoccoides) is tightly linked in repulsion with stripe rust resistance gene Yr5显示文摘Stripe rust and powdery mildew are both devastating diseases for durum and common wheat.Pyramiding of genes conferring resistance to one or more diseases in a single cultivar is an important breeding approach to provide broader spectra of resistances in wheat improvement. A new powdery mildew resistance gene originating from wild emmer(Triticum turgidum var.dicoccoides) backcrossed into common wheat(T. aestivum) line WE35 was identified. It conferred an intermediate level of resistance to Blumeria graminis f. sp. tritici isolate E09 at the seedling stage and a high level of resistance at the adult plant stage. Genetic analysis showed that the powdery mildew resistance in WE35 was controlled by a dominant gene designated Pm64. Bulked segregant analysis(BSA) and molecular mapping indicated that Pm64 was located in chromosome bin 2 BL4-0.50–0.89. Polymorphic markers were developed from the corresponding genomic regions of Chinese Spring wheat and wild emmer accession Zavitan to delimit Pm64 to a 0.55 cM genetic interval between markers WGGBH1364 and WGGBH612, corresponding to a 15 Mb genomic region on Chinese Spring and Zavitan 2 BL, respectively. The genetic linkage map of Pm64 is critical for fine mapping and cloning. Pm64 was completely linked in repulsion with stripe rust resistance gene Yr5. Analysis of a larger segregating population might identify a recombinant line with both genes as a valuable resource in breeding for resistance to powdery mildew and stripe rust. | Deyun Zhang Keyu Zhu Lingli Dong Yong Liang Genqiao Li Tilin Fang Guanghao Guo Qiuhong Wu Jingzhong Xie Yongxing Chen Ping Lu Miaomiao Li Huaizhi Zhang Zhenzhong Wang Yan Zhang Qixin Sun Zhiyong Liu | 2019 | The Crop Journal2019，7，6： | 8 |
| 7 | A MITE insertion into the 3′-UTR regulates the transcription of TaHSP16.9 in common wheat显示文摘Miniature inverted-repeat transposable elements(MITEs) are a type of DNA transposon frequently inserted into promoters, untranslated regions(UTR), introns, or coding sequences of genes. We found a 276-bp tourist-like MITE insertion in the 3′-UTR of a 16.9 k Da small heat shock protein gene(TaH SP16.9-3A) on chromosome 3A of common wheat. Haplotype analysis revealed two haplotypes, s HSP-W(wild type without MITE insertion) and s HSP-M(mutant with MITE insertion), present in wheat germplasm. Both semiquantitative PCR and quantitative real-time PCR analyses showed increased transcription levels of TaH SP16.9-3A in s HSP-M compared with those of s HSP-W after heat treatment at 42 °C. It appeared that the MITE insertion into the 3′-UTR enhances the transcription of TaH SP16.9-3A. | Jingting Li Zhenzhong Wang Huiru Peng Zhiyong Liu | 2014 | The Crop Journal2014，2，6： | 5 |
| 8 | Petroleum geological characteristics of Kela-2 gas field显示文摘The Kela-2 gas field is located in the center ofKelasu structural belt in Kuqa Depression. This trap is oneof a series of traps in the folded belts which are distributed ina string of pearls in the dual structure. The primary gas-bearing layers are sandstone of Lower Cretaceous K1bswhile the secondary layers are dolomite member and gluten-ite member of Lower Tertiary E1-2km and sandstone ofLower Cretaceous K1b. The main component of natural gasis methane whose content is higher than 97%. It is charac-terized by dry gas whose source rock is Jurassic coal meas-ure. The Kela-2 structural trap was formed during the Xiyuperiod and then became a reservoir in the late time. The res-ervoir formed late and the thick seal rock of Lower Tertiarygipsmantle are the avail reason why the giant Kela-2 gasfield has been well kept. The abnormal high pressure of theKela-2 gas field results from the strong structural compres-sion in the northern part during the Xiyu period. | JIA Chengzao ZHOU Xinyuan WANG Zhaoming LI Qiming PI Xuejun CAI Zhenzhong HU Xiaoyong | 2002 | Chinese Science Bulletin2002，47，S1： | 4 |
| 9 | Sum-frequency generation in on-chip lithium niobate microdisk resonators显示文摘We report the first observation, to the best of our knowledge, of sum-frequency generation in on-chip lithium niobate microdisk resonators. The sum-frequency signal in the 780 nm band, distinct in wavelength from secondharmonic signals, was obtained in lithium niobate microresonators under the pump of two individual 1550 nm band lasers. The sum-frequency conversion efficiency was measured to be 1.4 × 10^(-7) mW^(-1). The dependence of the intensities of the nonlinear signals on the total pump power and the wavelength of one pump laser was investigated while fixing the wavelength of the other. This work paves the way for applications of on-chip lithium niobate microdisk resonators ranging from infrared single-photon detection to infrared spectroscopy. | ZHENZHONG HAO JIE WANG SHUQIONG MA WENBO MAO FANG BO FENG GAO GUOQUAN ZHANG JINGJUN XU | 2017 | Photonics Research2017，5，6： | 3 |
| 10 | Chemical Fingerprint for Identification and Quality Control of Saccharides in Danhong Injection Based on HPLC-ELSD with Chemometrics显示文摘Chemical fingerprinting has been widely used for the quality control of complex natural products including traditional Chinese medicines and botanical drugs. However, there is still lack of appropriate method to monitor the batch-to-batch consistency of hydrophilic constituents, such as saccharides and oligosaccharides. In the present study, we developed a novel approach based on high performance liquid chromatography with evaporative light scattering detector(HPLC-ELSD) for establishing saccharide fingerprinting of Danhong Injection(DHI), which is a widely used botanical drug for treating cardiovascular diseases. Major saccharides in DHI were isolated and four compounds including fructose, glucose and two oligosaccharides were identified. The structures of two novel saccharides named glycerol-1-O-galactfpyranosyl-(1→4)-O-arabmofuranoside, and glycerol-1-O-galactpyranosyl-(1→4)[O-arabmfuranosyl-(1→3)]-O-arabinofuranoside were confirmed by NMR, HR-ESI-MS and GC-MS for the first time. The establishment approach was successfully applied to distinguishing 12 batches of DHI from other botanical drugs with the aid of principle component analysis as well as to evaluating batch-to-batch consistency with the help of calculating similarity of tmgerprints. Our findings indicate that the chemical fingerprint of saccharides can be a useful tool for the quality control of complex natural products. | LI Hao YANG Zhenzhong WANG Jiaojiao AN Yun WANG Chenchen GUO Xiaoguang WANG Yi | 2019 | Chemical Research in Chinese Universities2019，35，5： | 3 |
| 11 | Hollow Gradient-Structured Iron-Anchored Carbon Nanospheres for Enhanced Electromagnetic Wave Absorption显示文摘In the present paper,a microwave absorber with nanoscale gradient structure was proposed for enhancing the electromagnetic absorption performance.The inorganic-organic competitive coating strategy was employed,which can effectively adjust the thermodynamic and kinetic reactions of iron ions during the solvothermal process.As a result,Fe nanoparticles can be gradually decreased from the inner side to the surface across the hollow carbon shell.The results reveal that it offers an outstanding reflection loss value in combination with broadband wave absorption and flexible adjustment ability,which is superior to other relative graded distribution structures and satisfied with the requirements of lightweight equipment.In addition,this work elucidates the intrinsic microwave regulation mechanism of the multiscale hybrid electromagnetic wave absorber.The excellent impedance matching and moderate dielectric parameters are exhibited to be the dominative factors for the promotion of microwave absorption performance of the optimized materials.This strategy to prepare gradient-distributed microwave absorbing materials initiates a new way for designing and fabricating wave absorber with excellent impedance matching property in practical applications. | Cao Wu Jing Wang Xiaohang Zhang Lixing Kang Xun Cao Yongyi Zhang Yutao Niu Yingying Yu Huili Fu Zongjie Shen Kunjie Wu Zhenzhong Yong Jingyun Zou Bin Wang Zhou Chen Zhengpeng Yang Qingwen Li | 2023 | Nano-Micro Letters2023，15，1： | 2 |
| 12 | Off-design Characteristics of IGCC System Based on Two-stage Coal-slurry Gasification Technology显示文摘整体煤气化联合循环(integrated gasification combinedcycle,IGCC)机组在一定情况下处于非设计工况运行。为了研究IGCC系统变工况特性,采用ThermoFlex软件建立基于两段式水煤浆气化技术的200 MW级整体煤气化联合循环系统模型,主要考查燃气轮机负荷、整体空分系数Xas、大气温度、大气压力对系统性能的影响。研究结果表明,降低燃气轮机负荷或者提高大气温度系统效率均呈先升高而后降低的趋势。整体空分系数Xas增加,机组发电效率降低。大气压力对系统效率影响较小。上述条件下采用两段水煤浆气化技术,系统性能可以得到有效改善。研究结果可为采用两段式水煤浆气化技术的IGCC系统的设计、运行提供参考。 | LIU gaoxin WU Shaohua LI Zhenzhong WANG Yang | 2012 | 中国电机工程学报2012，32，14： | 2 |
| 13 | Information theory in nonlinear error growth dynamics and its application to predictability:Taking the Lorenz system as an example显示文摘In nonlinear error growth dynamics,the initial error cannot be accurately determined,and the forecast error,which is also uncertain,can be considered to be a random variable.Entropy in information theory is a natural measure of the uncertainty of a random variable associated with a probability distribution.This paper effectively combines statistical information theory and nonlinear error growth dynamics,and introduces some fundamental concepts of entropy in information theory for nonlinear error growth dynamics.Entropy based on nonlinear error can be divided into time entropy and space entropy,which are used to estimate the predictabilities of the whole dynamical system and each of its variables.This is not only applicable for investigating the dependence between any two variables of a multivariable system,but also for measuring the influence of each variable on the predictability of the whole system.Taking the Lorenz system as an example,the entropy of nonlinear error is applied to estimate predictability.The time and space entropies are used to investigate the spatial distribution of predictability of the whole Lorenz system.The results show that when moving around two chaotic attractors or near the edge of system space,a Lorenz system with lower sensitivity to the initial field behaves with higher predictability and a longer predictability limit.The example analysis of predictability of the Lorenz system demonstrates that the predictability estimated by the entropy of nonlinear error is feasible and effective,especially for estimation of predictability of the whole system.This provides a theoretical foundation for further work in estimating real atmospheric multivariable joint predictability. | LI AiBing ZHANG LiFeng WANG QiuLiang LI Bo LI ZhenZhong WANG YiQing | 2013 | Science China Earth Sciences2013，56，8： | 2 |
| 14 | A mobile application framework of the BIM-based facility management system under the cross-platform structure显示文摘The building information model/modeling(BIM) technology is currently applied in a broad range of applications and research for facility management,while the BIM-based mobile FM is difficult owing to various factors and environments.For example,the mobile applications usually require frequent cross-equipment compatibility.This paper proposes a reasonable BIM-based FM cross-platform framework and develops a mobile application on the basis of an existing BIM-based FM system.The developed mobile application is applied in a case study of a metro station project in Guangzhou to verify its effectiveness in FM practice.It helps maintenance staff in viewing BIMs,accessing related information,and updating maintenance records in a unique platform.The test results demonstrate that the proposed BIM-based cross-platform framework meet the FM application requirements and supports the extension of FM functions. | Xiao Yaqi Hu Zhenzhong Wang Wei Chen Xiangxiang | 2016 | Computer Aided Drafting,Design and Manufacturing2016，26，1： | 2 |
| 15 | Synthesis of 3-D ordered macroporous silicate using the template formed from monodispersed polystyrene latex显示文摘Based on the template formed from monodispersed polystyrene (PS) latex, a modified fast sol-gel process was employed to synthesize a three-dimensional ( 3-D ) ordered macroporous silica material after removing the template by calcination at high temperature. It was indicated that there existed highly ordered packed pores within the whole silica material by SEM morphology observation. It was also found that the pores were interconnected. The pore size could be controlled mainly by varying the particle size of the latex ranging from 101 to 102 nm. The formation process of the ordered pores was also preliminarily discussed. | Ql Kai YANG Zhenzhong WANG Lijun LIU Zhengping ZHAO Delu | 2000 | Chinese Science Bulletin2000，45，11： | 2 |
| 16 | In situ TEM studies of oxygen vacancy migration for electrically induced resistance change effect in cerium oxides显示文摘 | Peng Gao Zhenzhong Wang Wangyang Fu Zhaoliang Liao Kaihui Liu Wenlong Wang Xuedong Bai Enge Wang | 2009 | Micron2009，，4： | 2 |
| 17 | Realizing ranged performance in SnTe through integrating bands convergence and DOS distortion显示文摘As a typical IV-VI compound,SnTe has aroused widely attentions in the thermoelectric community due its similar crystal and band structures with PbTe.However,both the large number of inherent Sn vacancies and high thermal conductivity result in inferior thermoelectric performance in intrinsic SnTe over a broad temperature.In this work,we successfully improved those disadvantages of SnTe via stepwisely Pb heavily alloying and then In doping.A significantly wide fraction of Pb into SnTe(0-50%)achieves multiple effects:(a)the carrier concentration of SnTe is reduced through decreasing Sn vacancies via alloying high solution Pb atoms in the matrix;(b)the band structure is optimized through promoting the convergence of the two valence bands,simultaneously enhancing the Seebeck coefficient;(c)HAADF-STEM coupled with EDS results illustrate that guest Pb atoms randomly and uniformly occupied Sn atomic sites in the matrix,concurrently strengthening the phonon scattering.Furthermore,we introduced indium into Sn_(0.6)Pb_(0.4)Te system to create resonant states further enlarging the power factors at low-medium temperature.The integration of bands convergence and DOS distortion achieves a considerably high ZT_(ave) of~0.67 over the wide temperature range of 300-823 K in(Sn_(0.6)Pb_(0.4))_(0.995)In_(0.005)Te sample. | Huimei Pang Xiuxiu Zhang Dongyang Wang Rong Huang Zhenzhong Yang Xiao Zhang Yuting Qiu Li-Dong Zhao | 2022 | Journal of Materiomics2022，8，1： | 2 |
| 18 | Validation of different personalized risk models of chemotherapy-induced nausea and vomiting:results of a randomized,double-blind,phase III trial of fosaprepitant for cancer patients treated with high-dose cisplatin显示文摘Background:Highly emetogenic chemotherapy induces emesis in cancer patients without prophylaxis.The purpose of this study was to evaluate the efficacy and safety of a fosaprepitant-based triple antiemetic regimen for the prevention of chemotherapy-induced nausea and vomiting(CINV)in patients with solid malignant tumors,determine risk factors and externally validate different personalized risk models for CINV.Methods:This phase III trial was designed to test the non-inferiority of fosaprepitant toward aprepitant in cancer patients who were to receive the first cycle of single-day cisplatin chemotherapy.The primary endpoint was complete response(CR)during the overall phase(OP)with a non-inferiority margin of 10.0%.Logistic regression modelswere used to assess the risk factors ofCRand no nausea.To validate the personalized risk models,the accuracy of the risk scoring systems was determined by measuring the specificity,sensitivity and area under the receiver operating characteristic(ROC)curve(AUC),while the predictive accuracy of the nomogram was measured using concordance index(C-index).Results:A total of 720 patients were randomly assigned.CR during the OP in the fosaprepitant group was not inferior to that in the aprepitant group(78.1%vs.77.7%,P=0.765)with a between-group difference of 0.4%(95%CI,-5.7%to 6.6%).Female sex,higher cisplatin dose(≥70 mg/m2),no history of drinking and larger body surface area(BSA)were significantly associated with nausea.The AUC for the acute and delayed CINV risk indexes was 0.68(95%CI:0.66-0.71)and 0.66(95%CI:0.61-0.70),respectively,and the C-index for nomogram CINV prediction was 0.59(95%CI,0.54-0.64).Using appropriate cutoff points,the three models could stratify patients with high-or low-risk CINV.No nausea and CR rate were significantly higher in the low-risk group than in the high-risk group(P<0.001).Conclusions:Fosaprepitant-based triple prophylaxis demonstrated non-inferior control for preventing CINV in patients treated with cisplatin-base chemotherapy.Female cancer patients without a history of alcohol consumption,with larger BSA and received high-dose cisplatin might be more vulnerable to CINV.Three personalized prediction models were well-validated and could be used to optimize antiemetic therapy for individual patients. | Yuanyuan Zhao Bing Zhao Gang Chen Yinlan Chen Zijun Liao Haiming Zhang Weineng Feng Yinyin Li Heng Weng Weidong Li Yuefen Zhou Biyong Ren Yanda Lu Jianhua Chen Zhenteng Liu Zhenzhong Su Wenliang Wang Li Zhang | 2023 | Cancer Communications2023，43，2： | 2 |
| 19 | The pest status of Bemisia tabaci in China and non- chemical control strategies 显示文摘 | Ren Shunxiang Wang Zhenzhong Qiu Baoli | 2001 | Entomologica Sinica2001，18，： | 1 |
| 20 | Knowledge sharing in Chinese eonstruclion project teams and its affecting factors: an empirical study显示文摘 | ZHENZHONG MA LIYUN QI KEYI WANG | 2008 | Chinese Management Studies2008，2，2： | 1 |
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