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| 1 | Tumor suppressor miR-128-3p inhibits metastasis and epithelial-mesenchymal transition by targeting ZEB1 in esophageal squamous-cell cancer显示文摘MicroRNAs (miRNAs ) 是在 post-transcriptional 层次调整多重生物功能的一些短 RNA,例如 tumorigenic 过程,煽动性的损害和房间 apoptosis。(ZEB1 ) 锌手指电子盒子有约束力的 homeobox 因素 1 是上皮间充质的转变(EMT ) 的一个关键调停人。它包括人的食道的有鳞房间的癌(ESCC ) 导致各种各样的癌症的恶意的前进。在这研究,我们发现 miR-128-3p 由使用 PCR 是在 ESCC 纸巾和房间的 downregulated。而且, miR-128-3p 的下面调整的表示被证明与 ESCC 病人的差的预后被联系并且可能被认为是一个独立预示的因素。然后,我们在 ESCC 房间检验了 miR-128-3p 的角色,并且发现 miR-128-3p 能在 vitro 压制房间迁居和侵略。而且, ZEB1 被证实是由酶记者试金的 miR-128-3p 的一个直接目标。营救实验证明 EMT 被 miR-128-3p 经由 ZEB1 的抑制调整。一起拿所有,我们断定 miR-128-3p 压制 EMT,经由 ZEB1 的转移,和 miR-128-3p 可以是在 ESCC 的一个批评调停人。 | Lili Zhao Rui Li Shanling Xu Yi Li Pei Zhao Wei Dong Zhenjun Liu Qian Zhao Bo Tan | 2018 | Acta Biochimica et Biophysica Sinica2018，50，2： | 21 |
| 2 | Kinematics and dynamics of a particle on a non-simple harmonic vibrating screen显示文摘 | Lijun Wang Zhenjun Ding Shuang Meng Huijun Zhao Huiqiang Song | 2017 | Particuology2017，15，3： | 14 |
| 3 | Saving energy in the heat pump air conditioning system driven by gas engine 显示文摘 | Xu Zhenjun Yang Zhao | 2009 | Energy andBuildings2009，41，2： | 1 |
| 4 | Saving energy in the heat pump air conditioning system driven by gas engine 显示文摘 | Xu Zhenjun Yang Zhao | 2009 | Energy and Buildings2009，41，2： | 1 |
| 5 | In vitro reactivity of penicilloyl and penicillanyl albumin and polylysine conjugates with IgE-antibody显示文摘 | Zhenjun Zhao Michael Batley Claudio D’Ambrosio Brian A Baldo | 2000 | Journal of Immunological Methods2000，，1： | 1 |
| 6 | Tear film break‐up time in rabbits显示文摘 | Xiaojia E Wei Maria Markoulli Zhenjun Zhao Mark DP Willcox | 2012 | Clin Exp Optom2012，，1： | 1 |
| 7 | Effect of Build Direction on Fatigue Performance of L-PBF 316L Stainless Steel显示文摘The microstructure and fatigue and tensile properties of 316 L stainless steel fabricated via laser powder bed fusion(L-PBF)were investigated.Two 316 L stainless steel specimens with different loading directions which are either perpendicular to or parallel to building direction were prepared by L-PBF process.The results of X-ray diffraction tomography showed that there was no significant difference in morphology and size/distribution of the defects in the HB and VB samples.Since long axis of columnar grains is generally parallel to the build direction,the fatigue crack encounters more grain boundaries in VB samples under cyclic loading,which led to enhanced fatigue resistance of VB samples compared with HB sample.In contrast to HB sample,the VB sample has a higher fatigue strength due to a higher resistance to localized plastic deformation under cyclic loading.The differences in fatigue properties of L-PBF 316 L SS with different build directions were predominantly controlled by solidification microstructures. | Chenfan Yu Yuan Zhong Peng Zhang Zhenjun Zhang Congcong Zhao Zhefeng Zhang Zhijian Shen Wei Liu | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，4： | 1 |
| 8 | Toxic effects of enrofloxacin on growth rate and catalase activity in Eisenia fetida显示文摘 | Yuhong Gao Xinsheng Sun Zhenjun Sun Na Zhao Yurong Li | 2008 | Environmental Toxicology and Pharmacology2008，，2： | 1 |
| 9 | Saikosaponin?d suppresses the expression of cyclooxygenase?2 throughthe phospho?signal transducer and activator of transcription 3/hypoxia?induciblefactor?1α pathway in hepatocellular carcinoma cells显示文摘 | Shuixiang He Guifang Lu Helei Hou Zhenjun Zhao Zhanfang Zhu Xinlan Lu Jinghong Chen Zhilun Wang | 2014 | Molecular Medicine Reports2014，，5： | 1 |
| 10 | Toxic effects of enrofloxacin on growth rate and catalase activity in Eisenia fetida显示文摘 | Yuhong Gao Xinsheng Sun Zhenjun Sun Na Zhao Yurong Li | 2008 | Environmental Toxicology and Pharmacology2008，，2： | 1 |
| 11 | Unfolding and Conformational Variations of Thrombin‐Binding DNA Aptamers: Synthesis, Circular Dichroism and Molecular Dynamics Simulations显示文摘 | Lidan Sun Hongwei Jin Xiaoyang Zhao Zhenming Liu Yifu Guan Zhenjun Yang Liangren Zhang Lihe Zhang | 2014 | ChemMedChem2014，，5： | 1 |
| 12 | Dynamics,stability,and control of a four-cable mount system for wind tunnel test显示文摘A four-cable mount system is proposed for full-model wind tunnel flutter tests,which may adjust the pitch and roll attitude of the aircraft scaled model and ensure that the model is not subjected to cable tension.The system provides sufficient support to simulate the free flight of the aircraft by applying appropriate spring stiffness and cable tensions.The proposed fourcable mount system is modeled based on Lagrange mechanics,and its dynamics equations consider aerodynamic effects.The singularity of the system and its bifurcation characteristics under flow conditions are analysed to determine the supercritical bifurcation phenomenon for different tension levels and distances from the front suspension point to the mass centre of the model.The mathematical expressions of the longitudinal flight stability of the cable mount system are derived by linearising the system dynamics equations using small perturbations.The influence of the cable tension,spring stiffness,suspension point position,and other factors on the flight stability of the aircraft are analysed.A feedforward control algorithm is proposed to minimize the total elastic potential energy of the system.The results show that the model is in the level flight state when the elastic potential energy of the four-cable mount system is minimized.A feedback control design method is proposed based on the Lyapunov stability theory to derive the closed-loop stability conditions.The system dynamics model that includes the aircraft rigid body model,flexible cables,pulleys,springs,aerodynamic model,and servo motor control is established using the flexible multibody dynamics method.A multibody dynamics solver and Simulink are used to simulate the attitude adjustment of the model in the wind tunnel and verify the supercritical bifurcation characteristics of the system and the effectiveness of the feedback and feedforward control. | Zhenjun ZHAO Zhanwei ZHAO Yu YAN Kaichun ZENG Xiaojun SHI Han WU | 2023 | Chinese Journal of Aeronautics2023，36，2： | 0 |
| 13 | Distribution Patterns of Synechococcus Indicated Their Environmental Constraints and Related Geochemical Processes in the Yellow Sea显示文摘Synechococcus is a widely distributed photosynthetic pico-phytoplankton,which contributes mainly to carbon fixation and maintains the stability of the marine ecosystem.To investigate its distribution patterns in the Yellow Sea,seawater samples were collected during September 2018.Results of flow cytometry analysis showed that the Synechococcus abundance ranged from 6.36×10^(2) to 4.51×10^(4) cells mL^(−1),which correlated with salinity(P<0.01)and temperature(P<0.05).At deeper off-shore sites,Synecho-coccus showed high abundance at the subsurface thermo-halocline,which was in accordance with chlorophyll a(Chl a)content along the vertical column.Based on the high-throughput sequencing data of rpoC1(partial gene encoding RNA polymerase),two Synechococcus subclusters,S5.1 and S5.2,were found to coexist in the studied area.Several clades of S5.1,including Clades I,II,and III,were the dominant components,accounting for 6.63%,26.11%,and 45.5%of the total genus,respectively.Redundancy analysis(RDA)showed that nitrite was the main environmental factor that explained the genus composition among samples.Fur-thermore,co-occurrence network revealed that the main phyla that coexisted with Synechococcus were Proteobacteria,Bacteroidetes,Actinobacteria,Planctomycetes,and Verrucomicrobia,which were involved in the carbon(C),nitrogen(N),sulfur(S),and manga-nese(Mn)cycles.Overall,Synechococcus exhibited biogeographic distribution correlated with temperature-salinity and nitrite in the Yellow Sea,and their geochemical function showed diverse but should be further verified in the future. | ZHOU Yuting WANG Ting CHEN Xi QIN Song ZHAO Zhenjun GUO Xinyi LI Jialin | 2022 | Journal of Ocean University of China2022，21，2： | 0 |
| 14 | Uniaxial compressive behaviour of a FRP standing support made of mine wastes显示文摘Twenty-seven specimens were tested to investigate the uniaxial compression behaviour of an innovative standing support for underground space applications.The innovative standing support consisted of an external fibre reinforced polymer(FRP)jacket and the infill column made of cementitious grout,tailings and coal wash rejects.Effects of the FRP layers number and water to the cementitious grout(w/g)ratio were evaluated.Test results indicated that lower w/g ratios produced stronger infill columns.With FRP confinement,the standing support demonstrated strain-hardening loading characteristics with a significant improvement in both strength and ductility.The highest strength and strain of the specimens achieved was 58.4 MPa and 11.8%respectively.Compared with the unconfined specimens,the confinement with four FRP layers increased the specimen strength and associated strain up to 3.6 and 27.0 times respectively.A correlation between the compressive strength of the infill material and the ultrasonic pulse velocity was also investigated.Furthermore,a simple design-oriented model was proposed to predict the peak strength and the corresponding strain of the innovative standing support. | Zhenjun Shan Ting Ren Jan Nemcik Guanzheng Wu Liang Zhao | 2023 | International Journal of Mining Science and Technology2023，33，8： | 0 |
| 15 | Summer Monsoon Rainfall Variability in Central China over the Past 4700 Years and Its Possible Link to Solar Activity显示文摘Based on 467 pairs ofδ^(18)O andδ^(13)C records and 8230 Th dates from a stalagmite(BF4)from Xiniu Cave,central China,we present a reconstruction of 9-yr resolution monsoon rainfall record for the past 4700 years.Ourδ^(18)O record shows good coherence with East Asian summer monsoon(EASM)rainfall proxies from adjacent regions during the overlapping intervals,suggesting thatδ^(18)O signal in BF4 can be interpreted as a monsoon rainfall proxy.Theδ^(13) C variations are related to changes in local processes at the cave site,and regional rainfall and temperature changes.Based on theδ18 O record,a series of dry periods can be identified at 4500-4200,3500-3200,2800-2500,1900-1600,1400-1200,700-500,and 400-200 yr BP,while a series of wet periods can be identified at 4200-3600,2400-2200,3200-2800,1100-900,600-400,and 200-100 yr BP.Power spectrum analysis on ourδ^(18) O record reveals significant cycles at 470 and 80 yr,coinciding with the typical solar periodic variations.This result suggests that changes in solar activity play a dominant role in driving centennial-decadal monsoon rainfall variation in central China.Due to minor changes in solar irradiance(less than 1.5 W m^(-2))over the past 4700 years,our record was further compared to the El Nino-Southern Oscillation(ENSO)and Pacific Decadal Oscillation(PDO)proxies,confirming that solar forcing on monsoon rainfall changes might be amplified by the ENSO and PDO variations.From 600 to 150 yr BP(the Little Ice Age,LIA),a positive shift of 2‰can be revealed in both theδ^(18)O andδ^(13)C records,indicating a cold/dry climatic pattern.By comparing ourδ^(18)O andδ^(13)C records with historical documents,we suggest that the climatic deteriorations between 450 and 250 yr BP may have caused serious social unrest at the end of the Ming Dynasty. | Jingwei ZHANG Kan ZHAO Xinggong KONG Yongjin WANG Xianfang WANG Shushuang LIU Zhenjun WANG Hai CHENG R.Lawrence EDWARDS | 2021 | Journal of Meteorological Research2021，35，4： | 0 |
| 16 | 肺淋巴瘤的CT表现与病理对比(英文)显示文摘Objective: The aim of this study was to analyze the CT and pathology features of pulmonary lymphoma and to improve the understanding of this disease. Methods: The CT findings of 23 cases with pulmonary lymphoma were retrospectively analyzed and correlated with histopathology. Results: Of the 23 cases with pulmonary lymphoma, there were Hodgkin lymphoma (5 cases) and non-Hodgkin lymphoma (18 cases). Multiple lesions were assessed in 16 cases and single lesion in 7 cases. The imaging findings were classified into 3 types: lobar and segmental involvement type (9/23 cases, 39.13%), nodular or mass-like involvement type (8/23 cases, 34.78%) and mixed type (6/23 cases, 26.09%). Air bronchogram sign (14/23 cases, 60.8%), CT angiogram sign (12/23 cases, 52.17%), ground glass opacity nodules (3/23 cases, 13.04%) and lesion across pulmonary lobes (4/23,17.39%) were the characteristic features of pulmonary lymphoma. Conclusion: Relative characteristic CT features of pulmonary lymphoma could be revealed, which shows clinical significance in the diagnosis of the disease. | Miaoyu Zeng Zhenjun Zhao Jine Zhang Jinlei Li Yanhui Liu | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，11： | 0 |
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