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| 1 | Efficacy and safety of a novel anti-HER2 therapeutic antibody RC48 in patients with HER2-overexpressing,locally advanced or metastatic gastric or gastroesophageal junction cancer:a single-arm phase II study显示文摘Background:Current treatment options for human epidermal growth factor receptor 2(HER2)-overexpressing gastric cancer at third-line have shown limited clinical benefit.Further,there is no specific treatment for HER2 immunohistochemistry(IHC)2+and fluorescence in-situ hybridization-negative patients.Here,we report the efficacy and safety of a novel anti-HER2 antibody RC48 for patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer.Methods:Patients with HER2-overexpressing(IHC 2+or 3+),locally advanced or metastatic gastric or gastroesophageal junction cancer who were under at least second-line therapy were eligible and received RC482.5 mg/kg alone every 2 weeks.The primary endpoint was the objective response rate(ORR)assessed by an independent review committee.Secondary endpoints included progressionfree survival(PFS),overall survival(OS),duration of response,time to progression,disease control rate,and safety.Results:Of 179 patients screened,125 were eligible and received RC48 treatment.The ORR was 24.8%(95%confidence interval[CI]:17.5%-33.3%).The median PFS and OS were 4.1 months(95%CI:3.7-4.9 months)and 7.9 months(95%CI:6.7-9.9 months),respectively.The most frequently reported adverse events were decreased white blood cell count(53.6%),asthenia(53.6%),hair loss(53.6%),decreased neutrophil count(52.0%),anemia(49.6%),and increased aspartate aminotransferase level(43.2%).Serious adverse events(SAEs)occurred in 45(36.0%)patients,and RC48-related SAEs were mainly decreased neutrophil count(3.2%).Seven patients had adverse events that led to death were not RC48-related.Conclusions:RC48 showed promising activity with manageable safety,suggesting potential application in patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer who have previously received at least two lines of chemotherapy. | Zhi Peng Tianshu Liu Jia Wei Airong Wang Yifu He Liuzhong Yang Xizhi Zhang Nanfeng Fan Suxia Luo Zhen Li Kangsheng Gu Jianwei Lu Jianming Xu Qingxia Fan Ruihua Xu Liangming Zhang Enxiao Li Yuping Sun Guohua Yu Chunmei Bai Yong Liu Jiangzheng Zeng Jieer Ying Xinjun Liang Nong Xu Chao Gao Yongqian Shu Dong Ma Guanghai Dai Shengmian Li Ting Deng Yuehong Cui Jianmin Fang Yi Ba Lin Shen | 2021 | Cancer Communications2021，41，11： | 29 |
| 2 | 抑制换相失败期间送端电网过电压的控制策略研究显示文摘在受端交流系统发生故障时,基于电网换相换流器的直流输电系统存在换相失败的问题,这会导致直流输送功率中断,送端无功功率过剩将造成送端交流电网过电压,可能会造成风机等新能源设备脱网。因此,提出了一种抑制换相失败期间送端过电压的控制策略,在发生换相失败时快速投入逆变侧旁通对,并根据交流滤波器总输出无功功率计算出故障期间低压限流控制特性(VDCOL)的直流电流指令值。该策略可使直流系统在有功功率中断的运行模式下,保证送端换流阀能够正常换相并维持一定的直流电流,从而避免发生送端交流电网过电压的问题。仿真结果验证了该控制策略的有效性,在不同短路比的强、弱交流系统中均可适用。 | 刘琳 雷霄 孔祥平 林少伯 孙栩 谢国平 ZHOU Yifu | 2019 | 电力工程技术2019，38，3： | 15 |
| 3 | Electrochemical synthesis of nitric acid from air and ammonia through waste utilization显示文摘Commercial nitric acid(HNO3) and ammonia(NH3) are mostly produced through the Ostwald process and the Haber-Bosch process, respectively. However, high energy demand and enormous greenhouse gas accompy these processes. The development of economical and green ways to synthesize HNO3 and NH3 is highly desirable for solving the global energy and environmental crisis. Here, we present two energy-efficient and environmentally friendly strategies to synthesize HNO3 and NH3 at distributed sources, including the electrocatalytic oxidation of N2 in air to HNO3 and the electrocatalytic reduction of residual NO3- contamination in water to NH3. The isotope-labeling studies combined with theoretical calculation reveal the reaction path of the two proposed strategies, confirming the origin of the electrochemical products. Importantly, the electrooxidation-generated NO3- ions may also serve as reactants for the electroreduction synthesis of NH3 in the future. Our work may open avenues for energy-efficient and green production of HNO3 and NH3 at distributed sources. | Yuting Wang Yifu Yu Ranran Jia Chao Zhang Bin Zhang | 2019 | National Science Review2019，6，4： | 10 |
| 4 | Self-template synthesis of double-layered porous nanotubes with spatially separated photoredox surfaces for efficient photocatalytic hydrogen production显示文摘Improving charge carriers separation to achieve high photoconversion efficiency in heterogeneous photocatalysts is highly desirable.Herein,heterostructured ZnS@CdS double-layered porous nanotubes(PNTs),in which the spatially separated reduction and oxidation reaction sites lie on the outer and inner shell,respectively,are fabricated through a robust self-template conversion strategy.After selective photo-deposition of Ni and CoO_x as dual cocatalysts,Ni nanoparticles as electron collectors and reduction reaction sites are loaded on the outer shell,while CoO_x nanoparticles as hole collectors and oxidation reaction sites are loaded on the inner shells.As a result,a novel CoO_x/ZnS@CdS/Ni photocatalyst is obtained and shows high visible-light-driven photocatalytic hydrogen production activity owing to the synergistic effect of self-template-derived thin mesoporous heterojunctions and photo-depositionderived spatially separated dual cocatalysts,which can significantly provide driving force for the ordered transfer of photogenerated electrons and holes toward opposite direction and promote the surface catalytic reaction.Additionally,the facile strategy can be broadened to the preparation of CoO_x/ZnSe@CdSe/NiPNTs with enhanced photocatalytic activity. | Yani Xin Yi Huang Kui Lin Yifu Yu Bin Zhang | 2018 | Science Bulletin2018，63，10： | 9 |
| 5 | "One Belt and One Road" and Free Trade Zones--China's New Opening-up Initiatives显示文摘一条带和带道路和自由贸易地区是策略发展了响应的二瓷器新洞起来改变了国内、国际的情形。这些策略的实现能向中国提供一个更健全的市场经济系统和更好的外部环境。进一步发展成一个高收入国家不能仅仅帮助中国,而且便于另外的发展中的国家的工业化和现代化。 | Justin Yifu Lin | 2015 | Frontiers of Economics in China-Selected Publications from Chinese Universities2015，10，4： | 9 |
| 6 | Hydrogen evolution activity enhancement by tuning the oxygen vacancies in self-supported mesoporous spinel oxide nanowire arrays显示文摘到调子的灵巧的策略的发展在转变金属氧化物(TMO ) 的氧空缺(OV ) 内容是首要的获得便宜、稳定的 electrocatalysts,但是仍然高度质问。拿 NiCo 2 O 4作为一个模型系统,我们试验性地建立了灵巧的锻烧和电气化学的激活( EA )方法论戏剧性地增加 OV 的集中并且提供 OV 的集中怎么向电气化学的氢进化反应影响尖晶石 TMO 的表演的理论卓见(她的)。OV 富有的 NiCo 2 O 4 nanowire 数组被发现更高与更少 OV 比它的对应物在碱的媒介展出她的活动和更好的稳定性。她的活动在对在学习样品的 OV 的增加的集中的好同意的 electrocatalytic。360 妈的大当前的密度?? | Dali Liu Chao Zhang Yifu Yu Yanmei Shi Yu Yu Zhiqiang Niu Bin Zhang | 2018 | Nano Research2018，11，2： | 9 |
| 7 | Dendrite-free all-solid-state lithium batteries with lithium phosphorous oxynitride-modified lithium metal anode and composite solid electrolytes显示文摘Dendrite formation on lithium (Li) metal anode is a key issue which hinders the development of rechargeable Li battery seriously. A novel method for suppress!ng Li dendrites via using Li phosphorous oxynitride (UPON) modified Li anode and Li1.5Al0.5Ge1.5(PO4)3-poly(ethylene oxide)(Li bistrifluoromethane-sulfonimide)(LAGP-PEO(LiTFSI)) composite solid electrolyte in all-solid-state Li battery is proposed, and the effect of the thickness of UPON on Li anode performarice is also studied. LiPON film with a thickness of 500 nm exhibits satisfactory interface property between Li metal anode and the LAGP-PEO(LiTFSI) solid electrolyte. The LiPON film provides a uniform Li^+ flux across the interface and effectively inhibits the formation of Li dendrites in all-solid-state Li batteries. The assembled all-solid-state Li cell Li(LiPON)/LAGP-PEO(LiTFSI)/LiFePO4 delivers an initial discharge capacity of 152.4 mAh·g^-1 and exhibits good cycling stability and rate performanee at 50 ℃. | Chunhua Wang Guoliang Bai Yifu Yang Xingjiang Liu Huixia Shao | 2019 | Nano Research2019，12，1： | 8 |
| 8 | A fundamental theorem for eco-environmental surface modelling and its applications显示文摘We propose a fundamental theorem for eco-environmental surface modelling(FTEEM) in order to apply it into the fields of ecology and environmental science more easily after the fundamental theorem for Earth’s surface system modeling(FTESM). The Beijing-Tianjin-Hebei(BTH) region is taken as a case area to conduct empirical studies of algorithms for spatial upscaling, spatial downscaling, spatial interpolation, data fusion and model-data assimilation, which are based on high accuracy surface modelling(HASM), corresponding with corollaries of FTEEM. The case studies demonstrate how eco-environmental surface modelling is substantially improved when both extrinsic and intrinsic information are used along with an appropriate method of HASM. Compared with classic algorithms, the HASM-based algorithm for spatial upscaling reduced the root-meansquare error of the BTH elevation surface by 9 m. The HASM-based algorithm for spatial downscaling reduced the relative error of future scenarios of annual mean temperature by 16%. The HASM-based algorithm for spatial interpolation reduced the relative error of change trend of annual mean precipitation by 0.2%. The HASM-based algorithm for data fusion reduced the relative error of change trend of annual mean temperature by 70%. The HASM-based algorithm for model-data assimilation reduced the relative error of carbon stocks by 40%. We propose five theoretical challenges and three application problems of HASM that need to be addressed to improve FTEEM. | Tianxiang YUE Na ZHAO Yu LIU Yifu WANG Bin ZHANG Zhengping DU Zemeng FAN Wenjiao SHI Chuanfa CHEN Mingwei ZHAO Dunjiang SONG Shihai WANG Yinjun SONG Changqing YAN Qiquan LI Xiaofang SUN Lili ZHANG Yongzhong TIAN Wei WANG Ying’an WANG Shengnan MA Hongsheng HUANG Yimin LU Qing WANG Chenliang WANG Yuzhu WANG Ming LU Wei ZHOU Yi LIU Xiaozhe YIN Zong WANG Zhengyi BAO Miaomiao ZHAO Yapeng ZHAO Yimeng JIAO Ufra NASEER Bin FAN Saibo LI Yang YANG John PWILSON | 2020 | Science China Earth Sciences2020，63，8： | 7 |
| 9 | Wet-chemistry synthesis of cobalt carbide nanoparticles as highly active and stable electrocatalyst for hydrogen evolution reaction显示文摘转变金属碳化物(TMC ) nanomaterials 正在答应选择到磅,并且广泛地为电气化学的氢进化反应被用作异构的 electrocatalysts (她的) 。在这个工作,综合的导致溴化物的湿化学的策略公司 2 C nanoparticles (NP ) 被开发。如此的 NP 展出了高 electrocatalytic 活动(= 为 j = 的 181 mV 10 | Siwei Li Ce Yang Zhen Yin Hanjun Yang Yifu Chen Lili Lin Mengzhu Li Weizhen Li Gang HU Ding Ma | 2017 | Nano Research2017，10，4： | 7 |
| 10 | Low Cycle Fatigue and Strengthening Mechanism of Cold Extruded Large Diameter Internal Thread of Q460 Steel显示文摘高张力钢(LDITHSS ) 的内部线由传统的方法生产了的大直径总是有低精确性和短生活的问题。与传统的方法相比,冷挤出过程是一个有效工具认识到更高的精确性和长寿。LDITHSS 的低周期的疲劳性质被实验获得,并且疲劳裂缝的开始和繁殖被扫描电子显微镜(SEM ) 观察。基于机械性质,表面微观结构和剩余应力,冷渗出的大直径的加强的机制内部线(LDIT ) 被讨论。结果证明新谷物或亚谷物能在冷挤出期间由于谷物分割和谷物精炼在 LDIT 的表面上被形成。含纤维的结构是伸长并且在渗出的表面上沿着导致剩余的牙齿表面的正常方向优化了压缩应力出现。在冷挤出以后的 LDIT 的最大的紧张压力被发现是 192.55 kN。在低应力骑车下面,线上的收益压力增加,裂缝还原剂的繁殖率,吗疲劳生活因此与减少的表面谷物直径和生活增加到 45.539 的平均疲劳显著地被改进???蟳?寪螥??????蟳??鲢駻?媣??鯣???????????廩?仙哠??????矙璣???吗??????????????????蟳龢駻???????辧????????鲥?????焀?焘?焘?? | MIAO Hong MEI Qing YUAN Jingyun ZHENG Zaixiang JIN Yifu ZUO Dunwen | 2016 | Chinese Journal of Mechanical Engineering2016，29，3： | 7 |
| 11 | Seventy Years of Economic Development: A Review from the Angle of New Structural Economics显示文摘This review paper provides a new narrative by combing through the experiences of structural transformation among developing countries and discussing the roles of government and market in different contexts.Country performance has been influenced by the prevailing development thinking:the structuralism in the 1950s-1970s,which stresses an active government's role to overcome market failures for industrialization,and the neoliberalism in the 1980s-present,which advocates for eliminating government failures to build up a well-functioning market.We find that almost all countries failing by following structuralism in their industrialization and neoliberalism in their transition to a market economy,and the few countries successful in catching up have a few characteristics that go against the prevailing structuralism and neoliberalism.The new structural economics,generated from the experiences of successful East Asian economies and proposing active facilitating roles of government in a market economy to remove market failures,will gain traction and take root. | Justin Yifu Lin Yan Wang | 2020 | China & World Economy2020，28，4： | 7 |
| 12 | Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1显示文摘Multisystem manifestations in myotonic dystrophy type 1(DM1)may be due to dosage reduction in multiple genes induced by aberrant expansion of CTG repeats in DMPK,including DMPK,its neighboring genes(SIX5 or DMWD)and downstream MBNLh However,direct evidence is lacking.Here,we develop a new strategy to generate mice carrying multigene heterozygous mutations to mimic dosage reduction in one step by injection of haploid embryonic stem cells with mutant Dmpk,Six5 and Mbnll into oocytes.The triple heterozygous mutant mice exhibit adult-onset DM1 phenotypes.With the additional mutation in Dmwd,the quadruple heterozygous mutant mice recapitulate many major manifestations in congenital DM1.Moreover,muscle stem cells in both models display reduced sternness,providing a unique model for screening small molecules for treatment of DM1.Our results suggest that the complex symptoms of DM1 result from the reduced dosage of multiple genes. | Qi Yin Hongye Wang Na Li Yifu Ding Zhenfei Xie Lifang Jin Yan Li Qiong Wang Xinyi Liu Liuqing Xu Qing Li Yongjian Ma Yanbo Cheng Kai Wang Cuiqing Zhong Qian Yu Wei Tang Wanjin Chen Wenjun Yang Fan Zhang Chen Ding Lan Bao Bin Zhou Ping Hu Jinsong Li | 2020 | Cell Research2020，30，2： | 7 |
| 13 | Optimization Strategies for Selective CO_(2) Electroreduction to Fuels显示文摘Capturing CO_(2) from the atmosphere and converting it into fuels are an effi cient strategy to stop the deteriorating greenhouse eff ect and alleviate the energy crisis.Among various CO_(2) conversion approaches,electrocatalytic CO_(2) reduction reaction(CO_(2) RR)has received extensive attention because of its mild operating conditions.However,the high onset potential,low selectivity toward multi-carbon products and poor cruising ability of CO_(2) RR impede its development.To regulate product distribution,previous studies performed electrocatalyst modifi cation using several universal methods,including composition manipulation,morphology control,surface modifi cation,and defect engineering.Recent studies have revealed that the cathode and electrolytes infl uence the selectivity of CO_(2) RR via pH changes and ionic eff ects,or by directly participating in the reduction pathway as cocatalysts.This review summarizes the state-of-the-art optimization strategies to effi ciently enhance CO_(2) RR selectivity from two main aspects,namely the cathode electrocatalyst and the electrolyte. | Yangfang Ling Qinglang Ma Yifu Yu Bin Zhang | 2021 | Transactions of Tianjin University2021，27，3： | 6 |
| 14 | Adipose tissue macrophage in immune regulation of metabolism显示文摘The prevalence of obesity and type 2 diabetes is escalating to an epidemic proportion worldwide.Obesity is known to be associated with a state of chronic,low-grade inflammation.Emerging lines of evidence have shown that both innate and adaptive immune responses play crucial roles in the control of metabolic homeostasis.Macrophages in adipose tissues are the essential effector cells in orchestrating metabolic inflammation,which is thought to promote the pathogenic progression of obesity and obesity-related disorders.Here we discuss our current understanding of the distinct modes of activation of adipose tissue macrophages,which can sense the metabolic cues and exert profound effects upon adipose homeostasis.Targeting macrophages in adipose tissues may provide new avenues for developing immunomodulation-based therapeutics against obesity and obesity-associated metabolic diseases. | Yifu Qiu Bo Shan Liu Yang Yong Liu | 2016 | Science China(Life Sciences)2016，59，12： | 6 |
| 15 | Refined chronology of prehistoric cultures and its implication for re-evaluating human-environment relations in the Hexi Corridor,northwest China显示文摘The reconstruction of high-resolution chronologies for prehistoric cultures is a prerequisite for understanding the history of human evolution and its relationship with environmental change, and is valuable for exploring the trajectory of transcontinental cultural exchanges in prehistoric time. The Hexi Corridor of northwest China was one of the earliest centers for long-distance culture exchange in the prehistoric world. The timing and sequence of cultural changes in this area remains poorly understood resulting from the lack of radiometric age control. This paper presents a refined radiocarbon(14 C) chronology to resolve the timing of human occupation and cultural evolution in the Hexi Corridor. Radiocarbon dating of crop remains, which have an annual life cycle, has the advantage of eliminating problems such as the carbon stored in ‘old wood’. As a result,14C dates from crop remains are used to test the validity of the14C dates derived from charcoal, bone and plant remains. The resultant database of ages is modelled using the Bayesian approach. The updated chronology presented in this paper shows generally good agreement with the original dates used to constrain cultural evolution in the Hexi Corridor. However, the occupation of the corridor by the Shajing and Shanma Late Bronze Age-Early Iron Age cultures appears to have taken place ~300 years later than previously thought. On the basis of comparing this updated chronology of cultural evolution with palaeoclimatic and historical records, it is proposed that the collapse of the Shajing and Shanma cultures occurred as a result of geopolitical impact rather than climate change. | Yishi YANG Shanjia ZHANG Chris OLDKNOW Menghan QIU Tingting CHEN Haiming LI Yifu CUI Lele REN Guoke CHEN Hui WANG Guanghui DONG | 2019 | Science China Earth Sciences2019，62，10： | 5 |
| 16 | Spatiotemporal evolution of prehistoric Neolithic-Bronze Age settlements and influencing factors in the Guanting Basin, northeast Tibetan Plateau显示文摘For almost two decades, the relationship between prehistoric natural disasters that struck the Guanting Basin in northeast Tibetan Plateau and the destruction of Lajia, an archeological site, has attracted scholarly attention and been widely discussed. Whereas most studies have focused on the impacts of disasters on a single site within the Guanting Basin, few have examined patterns of spatiotemporal evolution of human settlements from the Neolithic to the Bronze Age. Consequently, there is a lack of clarity on the processes and mechanisms underlying the evolution of prehistoric human-land relationships in the Guanting Basin. We therefore examined spatiotemporal variations in settlements in the Guanting Basin during the period, based on the locations, altitudes, and areas of archaeological sites. We found that four sites were located on the third terrace of the Yellow River during the late Yangshao period(5500–5000 cal yr BP) and distributed within a small area. During the period between the Majiayao and Qijia cultures(5300–3600 cal yr BP), the number of sites evidently increased and the scale and distribution of settlements expanded, with settlements generally shifting toward the lower elevation areas of the Guanting Basin.During the Xindian period(3400–2700 cal yr BP), the number and scale of sites showed a downward trend and the distribution of settlements contracted. The Xindian settlement underwent altitude-based spatial differentiation, with some groups moving to areas at higher altitudes and others remained in lower altitude areas. Moreover, we found that the number, scale, and distribution range of Neolithic and Bronze Age sites in the Guanting Basin were closely related to the evolution and distribution patterns of prehistoric cultures in the regions of Gansu and Qinghai, which were further affected by climate change and agricultural development. Furthermore, there is no evidence that the altitudinal distribution pattern of Neolithic and Bronze Age settlements in the Guanting Basin was influenced by paleofloods rather it was primarily influenced by changes in subsistence strategies. | CUI YiFu LIU YuJia MA MinMin | 2018 | Science China Earth Sciences2018，61，2： | 5 |
| 17 | Effects of 2'-O-methyl nucleotide on ligation capability of T4 DNA ligase显示文摘为了推进,理解结扎机制, T4 DNA 结扎效率上的 2-O-methyl 核苷酸(2 预兆) 的效果被调查。荧光回声精力转移试金被用来由 T4 DNA ligase 监视加入刻痕的进程。结果证明在刻痕的 5 结束和 3 结束的替换减少了在 48.7% | Bin Zhao Zhaoxue Tong Guojie Zhao Runqing Mu Hong Shang Yifu Guan | 2014 | Acta Biochimica et Biophysica Sinica2014，46，9： | 5 |
| 18 | Transition prediction and sensitivity analysis for a natural laminar flow wing glove flight experiment显示文摘Natural laminar flow technology can significantly reduce aircraft aerodynamic drag and has excellent technical appeal for transport aircraft development with high aerodynamic efficiency.Accurately and efficiently predicting the laminar-to-turbulent transition and revealing the maintenance mechanism of laminar flow in a transport aircraft’s flight environment are significant for developing natural laminar flow wings.In this research,we carry out natural laminar flow flight experiments with different Reynolds numbers and angles of attack.The critical N-factor is calibrated as 9.0 using flight experimental data and linear stability theory from a statistical perspective,which makes sure that the relative error of transition location is within 5%.We then implement a simplified e^(N) transition prediction method with a similar accuracy compared with linear stability theory.We compute the sensitivity information for the simplified eN method with an adjointbased method,using the automatic differentiation technique(ADjoint).The impact of Reynolds numbers and pressure distributions on TS waves is analyzed using the sensitivity information.Through the sensitivity analysis,we find that:favorable pressure gradients not only suppress the development of TS waves but also decrease their sensitivity to Reynolds numbers;there exist three special regions which are very sensitive to the pressure distribution,and the sensitivity decreases as the local favorable pressure gradient increases.The proposed sensitivity analysis method enables robust natural laminar flow wings design. | Tihao YANG Hai ZHONG Yifu CHEN Yayun SHI Junqiang BAI Feifei QIN | 2021 | Chinese Journal of Aeronautics2021，34，8： | 5 |
| 19 | 细胞学方法治疗缺血性心脏病的新进展显示文摘尽管缺血性心脏病在防治手段,介入治疗方面有了很大的进展,但是缺血性心脏病仍然是世界上导致患者死亡最多的疾病之一.为了使缺血性心脏病患者心肌梗死部位心肌再生,研究人员尝试了多种物理治疗方法[1-3],如移植乳内动脉到坏死部位的心肌组织[4],或是应用药物治疗,如肝素[2],血管内皮生长因子(VEGF),肝素结合生长因子1和碱性成纤维细胞生长因子[7-10]. | Yifu Zhou Suna Wang Bogdan Kindzelski Keith A Horvath 程斌 黄益民 | 2014 | 心肺血管病杂志2014，33，6： | 4 |
| 20 | Diversity Analysis of Chlorophyll, Flavonoid, Anthocyanin, and Nitrogen Balance Index of Tea Based on Dualex显示文摘The chemical compositions of tea(Camellia sinensis)are affected by numerous factors,such as cultivar,climate,leaf position,and cultivation pattern.However,under the same conditions,the chemical compositions are mainly determined by varieties.Therefore,we investigated the genetic diversity of chemical compositions of tea tree resources in China to screen excellent germplasm resources.Three chemical compositions index(including chlorophyll index,flavonoid index,and anthocyanin index)and the nitrogen balance index of tea leaves were measured in 102 tea germplasms planted in Chinese Tea Plants Improved Variety Germplasm Resources Nursery(CTPIVGRN)by Dualex on April 152019.Results showed that the chlorophyll,flavonoid,and anthocyanin contents and the nitrogen balance index significantly differed between the 102 tea germplasms.The genetic diversity index values were 2.005,2.246,1.599,and 1.838,and the average genetic diversity was 1.922.The 102 tea germplasms can be divided into four categories by cluster analysis under the genetic distance threshold of 11.These results suggest that the genetic diversity of tea germplasm resources in China is rich.This study’s results can serve as a basis for the diversified development and utilization of tea plant. | Yifu Liu Jiazhen Wang Yao Xiao Xiongwen Shi Yixia Zeng | 2021 | Phyton-International Journal of Experimental Botany2021，90，5： | 4 |
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