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| 1 | Enhancement and selective production of avermectin B by recombinants of Streptomyces avermitilis via intraspecific protoplast fusion显示文摘Among eight components of avermectin, B1 fractions have the most effective antiparasitic activities and the lowest level of toxic side-effects and are used widely in veterinary and agricultural fields. In-traspecific protoplast fusion between two strains of Streptomyces avermitilis, one an avermectin high producer (strain 76-05) and the other a genetically engineered strain containing the mutations aveDˉ and olmAˉ (strain 73-12) was performed for enhancement and selective production of avermectin B in the absence of oligomycin. Two recombinant strains (F23 and F29) were isolated and characterized with regards to the parental merits. F23 and F29 produced only the four avermectin B components with high yield and produced no oligomycin. The avermectin production of F23 and F29 was about 84.20% and 103.45% of the parental strain 76-05, respectively, and increased about 2.66-fold and 3.50-fold, re-spectively, compared to that of parental strain 73-12. F23 and F29 were genetically stable prototrophic recombinants and F29 was quite tolerant of fermentation conditions compared to avermectin high producer parental strain 76-05. The ability to produce avermectin B with high yield without the produc-tion of other avermectin components and oligomycin will make F23 and F29 useful strains for aver-mectin production. Strain F29's tolerance of fermentation conditions will also make it suitable for in-dustrial applications. | CHEN Zhi WEN Jia SONG Yuant WEN Ying LI JiLun | 2007 | Chinese Science Bulletin2007，52，5： | 10 |
| 2 | Multi-functional polyethersulfone nanofibrous membranes with ultra-high adsorption capacity and ultra-fast removal rates for dyes and bacteria显示文摘The adsorption technology has been widely applied in water remediation for contamination removal of dyes and bacteria,by virtue of the advantages of adsorption technology including high efficiency,energy conservation and ease of operation.Simultaneous removal of dyes and bacteria has been realized by some reported materials,but to achieve satisfactory adsorption amounts and rates remain an unmet goal for decades.Herein,a poly(methacrylatoethyl trimethyl ammonium chloride-co-methyl methacrylate)copolymer was synthesized,and then blended with polyethersulfone for the fabrication of nanofibrous membranes via electrospinning for the use of fast and massive removal of dyes and bacteria.Owing to the introduction of abundant quaternary ammonium groups,the maximum adsorption amount for methyl orange was up to 909.8 mg g^(-1).In addition,the modified nanofibrous membranes showed good recyclability,broad applications in severe environments,selective adsorption ability,and excellent dynamic removal performance.Especially,thanks to the abundant functional groups,the membranes showed fast adsorption ability for bacteria through electrostatic interaction.It should be noted that the clearance ratio for Staphylococcus aureus or Escherichia coli by 6 min of static adsorption could reach 93%or 90%for each.Additionally,dynamic removal ratio via filtration with the nanofibrous membranes could reach 99.7%for Staphylococcus aureus or 98.7%for Escherichia coli in 90 s.Therefore,the proposed approach towards the quaternary ammonium modified polyethersulfone nanofibrous membranes creates a new route for ultra-high adsorption capacity and ultra-fast removal rates for dyes and bacteria in water remediation. | Jianxu Bao Hang Li Yuanting Xu Shengqiu Chen Zhoujun Wang Chunji Jiang Huilin Li Zhiwei Wei Shudong Sun Weifeng Zhao Changsheng Zhao | 2021 | Journal of Materials Science & Technology2021，，19： | 4 |
| 3 | Transient receptor potential vanilloid I activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel α subunit-mediated sodium reabsorption显示文摘 | Li Li Wang FeiiWei Xing Liang Yi Cui Yuanting Gao Feng Zhong Jian Pu Yunfei Zhao Yu Yan Zhencheng Arendshorst William J Nilius Bemd Chen Jing'Liu Daoyan Zhu Zhiming | 2014 | Hypertension2014，642，： | 1 |
| 4 | A single mutation underlying phenotypic convergence for hypoxia adaptation on the Qinghai-Tibetan Plateau显示文摘Dear Editor,The Qinghai-Tibet Plateau(QTP)is the highest and largest plateau in the world;its altitude exceeds 4500 m on average,posing great physiological challenges such as severe hypoxia for endemic wild mammals on the plateau.1 To cope with such a harsh environment,the phylogenetically distant QTP endemic mammals have independently evolved similar morphological and physiological traits. | Donqming Xu Cuiping Yang Qiushuo Shen Shengkai Pan Zhen Liu Tongzuo Zhang Xin Zhou Menglong Lei Peng Chen Hui Yang Tao Zhang Yuanting Guo Xiangjiang Zhan Yongbin Chen Peng Shi | 2021 | Cell Research2021，31，9： | 1 |
| 5 | Association of a 76 kDa polypeptide with soluble starch synthase I activity in maize (cv B73) endosperm显示文摘 | Chen M Chse Hern YuanT K | 1994 | The Plant Journal1994，6，2： | 1 |
| 6 | Wave-dominated,mesotidal headland-bay beach morphodynamic classsfications of the Shuidong Bay in South China显示文摘Beach morphodynamic classifications have achieved extensive acceptance in foreign coastal geomorphological studies.Three beaches located in different zones of a headland-bay coast are classified according to a dimensionless fall parameter,a relative tide range parameter and a dimensionless embayment scaling parameter.Synchronous data,including wave,tide,sediment and beach morphology,are respectively collected from the tangential beach,the transitional beach and the shadow beach of the Shuidong Bay during each spring tide for 16 successive months.The research results indicate that(1) the beach in the tangential zone falls between two major categories which are low tide terrace beaches with rips and barred beaches;the beach in the transitional zone exhibits two main types which are low tide bar/rip beaches and barred dissipative beaches;and the beach in the shadow zone mainly mirrors dissipative states with presence or absence of bars;and(2) the sequential changes and differences of beach states in different coastal zones reflect spatial and temporal variabilities of the headlandbay coast,totally meeting the actual measured beach morphology changes,showing that studies on wavedominated,meso-macrotidal beaches need to consider the influences of the tides.Meanwhile,the research mainly provides a framework about beach state studies,due to different beach states with different erosion patterns,which requires the need to strengthen the researches in this respect,in order to further enrich theoretical basis for a beach topography evolution,beach morphodynamic processes and beach erosion prevention in China. | YU Jitao DING Yuanting CHENG Huangxin CAI Lailiang CHEN Zishen | 2016 | Acta Oceanologica Sinica2016，35，7： | 1 |
| 7 | Pd catalysts supported on MnCeO x mixed oxides and their catalytic application in solvent-free aerobic oxidation of benzyl alcohol: Support composition and structure sensitivity显示文摘 | Yuanting Chen Huijian Zheng Zhen Guo Chunmei Zhou Chuan Wang Armando Borgna Yanhui Yang | 2011 | Journal of Catalysis2011，，1： | 1 |
| 8 | Time-varying clustering for local lighting and material design显示文摘This paper presents an interactive graphics processing unit (GPU)-based relighting system in which local lighting condition, surface materials and viewing direction can all be changed on the ffy. To sup- port these changes, we simulate the lighting transportation process at run time, which is normally impractical for interactive use due to its huge computational burden. We greatly alleviate this burden by a hierarchical structure named a transportation tree that clusters similar emitting samples together within a perceptually acceptable error bound. Furthermore, by exploiting the coherence in time as well as in space, we incrementally adjust the clusters rather than computing them from scratch in each frame. With a pre-computed visibility map, we are able to efficiently estimate the indirect illumination in parallel on graphics hardware, by simply summing up the radiance shoots from cluster representa- tives, plus a small number of operations of merging and splitting on clusters. With relighting based on the time-varying clusters, interactive update of global illumination effects with multi-bounced indirect lighting is demonstrated in applications to material animation and scene decoration. | HUANG PeiJie GU YuanTing WU XiaoLong CHEN YanYun WU EnHua | 2009 | Science in China(Series F)2009，52，3： | 1 |
| 9 | “1+1>2”:Highly efficient removal of organic pollutants by composite nanofibrous membrane based on the synergistic effect of adsorption and photocatalysis显示文摘Adsorption and photocatalysis are regarded as two desirable technologies for wastewater remediation,but are still unsatisfactory in removal effect,eco-friendly regeneration and facile reusability.In this study,we developed a composite nanofibrous membrane material with excellent removal performance for organic pollutants based on synergistic adsorption and photocatalysis.A novel boron-doped,nitrogen-deficient graphitic carbon nitride(B-C3N4)photocatalyst as well as an amphiphilic copolymer of methyl methacrylate and acrylic acid(p(MMA-AA))were synthesized respectively,and then used to modify polyethersulfone for the fabrication of composite nanofibrous membrane with improved hydrophilicity,negativelycharge property and enhanced visible light response simultaneously.Subsequently,the synergistic effect of adsorption and photocatalytic degradation for organic pollutants were identified especially and resulted in an excellent removal efficiency even superior to the combination of adsorption and photocatalytic degradation,which could be called a“1+1>2”effect.In addition,the regeneration and reusability,the purification ability for multicomponent wastewater,and the photocatalytic mechanism,were investigated and discussed systematically.In this work,we not only prepared the nanofibrous membrane with synergistic effect of adsorption and photocatalysis,but also provided a versatile approach to design dualfunctional support material to ensure the practical applications of powdery photocatalyst in wastewater treatment. | Yuanting Xu Wanting Lin Dandan Yuan Shifan Chen Fang Li Yanping Long Chao He Weifeng Zhao Changsheng Zhao | 2022 | Journal of Materials Science & Technology2022，，29： | 1 |
| 10 | Designing uniform illumination systems by surface-tailored lens and configurations of LED arrays显示文摘 | Whang Allen Jong-Woei Yiyung Chen Yuanting Teng | 2009 | Journal of Display Technology2009，5，3： | 1 |
| 11 | Zerocrossing-based nonuniform sampling to deliver low-frequency fine structure cue for cochlear implant显示文摘 | Chen Fei Zhang Yuanting | 2011 | Digital Signal Processing2011，21，： | 1 |
| 12 | Interfacial engineering of 3D hollow CoSe_(2)@ultrathin MoSe_(2)core@shell heterostructure for efficient pH-universal hydrogen evolution reaction显示文摘Rational design and construction of low-cost and highly efficient electrocatalysts for hydrogen evolution reaction(HER)is meaningful but challenging.Herein,a robust three dimensional(3D)hollow CoSe_(2)@ultrathin MoSe_(2)core@shell heterostructure(CoSe_(2)@MoSe_(2))is proposed as an efficient HER electrocatalyst through interfacial engineering.Benefitting from the abundant heterogeneous interfaces on CoSe_(2)@MoSe_(2),the exposed edge active sites are maximized and the charge transfer at the hetero-interfaces is accelerated,thus facilitating the HER kinetics.It exhibits remarkable performance in pH-universal conditions.Notably,it only needs an overpotential(η10)of 108 mV to reach a current density of 10 mA·cm^(-2)in 1.0 M KOH,outperforming most of the reported transition metal selenides electrocatalysts.Density functional theory(DFT)calculations unveil that the heterointerfaces synergistically optimize the Gibbs free energies of H2O and H^(*)during alkaline HER,accelerating the reaction kinetics.The present work may provide new construction guidance for rational design of high-efficient electrocatalysts. | Lili Zhang Yuanting Lei Danni Zhou Chengli Xiong Zhuoli Jiang Xinyuan Li Huishan Shang Yafei Zhao Wenxing Chen Bing Zhang | 2022 | Nano Research2022，15，4： | 1 |
| 13 | Carbon-supported high-entropy Co-Zn-Cd-Cu-Mn sulfide nanoarrays promise high-performance overall water splitting显示文摘Transition metal sulfides with homogeneous multi-metallic elements promise high catalytic performance for water electrolysis owing to the unique structure and highly tailorable electrochemical property.Most existing synthetic routes require high temperature to ensure the uniform mixing of various elements,making the synthesis highly challenging.Here,for the first-time novel carbon fiber supported high-entropy Co-Zn-Cd-Cu-Mn sulfide(CoZnCdCuMnS@CF)nanoarrays are fabricated by the mild cation exchange strategy.Benefiting from the synergistic effect among multiple metals and the strong interfacial bonding between high-entropy Co-Zn-Cd-Cu-Mn sulfide nanoarrays and the carbon fiber support,CoZnCdCuMnS@CF exhibits superior catalytic activity and stability toward overall water splitting in alkaline medium.Impressively,CoZnCdCuMnS@CF only needs low overpotentials of 173 and 220 mV to reach the current density of 10 mA•cm^(−2),with excellent durability for over 70 and 113 h for hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)respectively.More importantly,the bifunctional electrode(CoZnCdCuMnS@CF||CoZnCdCuMnS@CF)for overall water splitting can deliver a small cell voltage of 1.63 V to afford 10 mA•cm^(−2) and exhibit outstanding stability of negligible decay after 73 h continuous operation.This work provides a viable synthesis route toward advanced high-entropy materials with great potential applications. | Yuanting Lei Lili Zhang Wenjing Xu Chengli Xiong Wenxing Chen Xu Xiang Bing Zhang Huishan Shang | 2022 | Nano Research2022，15，7： | 0 |
| 14 | Clinical features and outcome of 15 patients with recurrent endometrial cancer or atypical endometrial hyperplasia received primary fertility-sparing therapy followed by hysterectomy显示文摘Objective To investigate the clinical features and outcome of recurrent endometrial cancer(EC)or atypical endometrial hyperplasia(AEH)patients who underwent hysterectomy after fertility-sparing therapy.Methods Clinical data was retrospectively collected for 15 recurrent endometrial cancer or atypical endometrial hyperplasia patients who underwent hysterectomy in six hospitals from 2003 to 2019.According to the indicators of hysterectomy,patients were divided into four groups:7 patients who underwent direct hyesterectomy after the first relapse,4 due to re-treatment failure,1 after full term live birth,and 3 because of multiple recurrence.Clinical coexisting conditions,regimen and outcome of fertility-sparing therapy,pre-and post-operative pathological results,and prognosis were analyzed.Results(1)Fertility-spraring treatment was given to a total of 15 eligible patients,including 6 with EC and 9 with AEH.Median time interval from remission to recurrence was 12 months(range 3–92).Oral progestin-based medicine was the main fertility-sparing therapy in both primary treatment and re-treatment after recurrence.Six(6/8)patients received progestin combined with gonadotrophin releasing hormone agonist or metformin in three re-treatment groups.(2)Nine patients underwent hysterectomy and 6 staging surgery.Three patients had pathological upgrade after surgery.Five(5/10)EC patients had superficial myometrial invasion in postoperative pathology.All patients showed no evidence of disease in the median follow-up of 17 months(range 3–118).(3)Among seven patients who failed to re-treatment and had multiple recurrence,six were overweight/obesity and six had insulin resistance.Two of these patients had synchronous ovarian cancer in the postoperative pathology.Conclusion For the patients with recurrent EC or AEH after primary fertility-sparing therapy,overweight/obesity and insulin resistance might be the risk factors for re-treatment failure.Hysterectomy is recommended when patients had re-treatment failure or multiple recurrence;and generally the prognosis is favorable. | Yuanting Li Yiqin Wang Yijiao He Rong Zhou Huiru Tang Lijiang Xu Mian He Weili Li Chunlin Chen Weifeng Zhang Jianliu Wang | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，1： | 0 |
| 15 | 盐摄入通过PPARδ/脂联素介导的SGLT2通路调控糖稳态显示文摘高盐摄入是糖尿病发生高血压的主要危险因素.促进肾脏盐排泄可减少糖尿病的心血管损害,但摄盐与糖稳态的相互作用尚不清楚。 | Yu Zhao Peng Gao Fang Sun Qiang Li Jing Chen Hao Yu Li Li Xing Wei Hongbo He Zongshi Lu Xiao Wei Bin Wang Yuanting Cui Shiqiang Xiong Qianhui Shang Aimin Xu Yu Huang Daoyan Liu 祝之明 | 2017 | 科学新闻2017，19，4： | 0 |
| 16 | The Empirical Study of Board Structure and Firm Performance-Innovative Small Enterprises in China显示文摘This study took small enterprises listed from 2010 to 2015 as the empirical object.The board size,CEO duality,and ratio of independent directors were independent variables.The return on total assets,return on shareholders’equity and earnings per share were taken as the dependent variables,and three hypotheses were tested with SPSS.It is found that the board size was positively correlated with firm performance,but was not significant.There was no significant correlation between the ratio of independent directors and CEO duality on firm performance.This study suggests that optimizing the leadership structure of the board of directors can help improve the firm performance of enterprises. | Liling Yang Yuanting Chen | 2021 | Management Studies2021，9，3： | 0 |
| 17 | 三阴性乳腺癌基因组与转录组全景图:亚型及治疗策略显示文摘文章简介三阴性乳腺癌(triple-negative breast cancer,TNBC)是雌激素受体、孕激素受体和HER-2均为阴性的一群乳腺癌,缺乏有效靶向治疗,预后差,是乳腺癌学界的世界性难题。近年的研究表明TNBC是一个异质性很强的群体,为更全面而深入地认识这类疾病,寻找精准治疗的突破口,研究团队全面分析了465例原发性三阴性乳腺癌(TNBC)队列的临床、基因组学和转录组学数据。 | Yi-Zhou Jiang Ding Ma Chen Suo Jinxiu Shi Mengzhu Xue Xin Hu Yi Xiao Ke-Da Yu Yi-Rong Liu Ying Yu Yuanting Zheng Xiangnan Li Chenhui Zhang Pengchen Hu Jing Zhang Qi Hua Jiyang Zhang Wanwan Hou Luyao Ren Ding Bao Bingying Li Jingcheng Yang Ling Yao Wen-Jia Zuo Shen Zhao Yue Gong Yi-Xing Ren Ya-Xin Zhao Yun-Song Yang Zhenmin Niu Zhi-Gang Cao Daniel G.Stover Claire Verschraegen Virginia Kaklamani Anneleen Daemen John R.Benson Kazuaki Takabe Fan Bai Da-Qiang Li 王鹏 石乐明 黄薇 邵志敏 | 2020 | 科学新闻2020，，2： | 0 |
| 18 | Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol显示文摘Macrophages are critical sentinel cells armed with multiple regulated necrosis pathways,including pyroptosis,apoptosis followed by secondary necrosis,and necroptosis,and are poised to undergo distinct form(s)of necrosis for tackling dangers of pathogenic infection or toxic exposure.The natural BH3-mimetic gossypol is a toxic phytochemical that can induce apoptosis and/or pyroptotic-like cell death,but what exact forms of regulated necrosis are induced remains largely unknown.Here we demonstrated that gossypol induces pyroptotic-like cell death in both unprimed and lipopolysaccharide-primed mouse bone marrow-derived macrophages(BMDMs),as evidenced by membrane swelling and ballooning accompanied by propidium iodide incorporation and lactic acid dehydrogenase release.Notably,gossypol simultaneously induces the activation of both pyroptotic and apoptotic(followed by secondary necrosis)pathways but only weakly activates the necroptosis pathway.Unexpectedly,gossypol-induced necrosis is independent of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3(NLRP3)inflammasome,as neither inhibitor for the NLRP3 pathway nor NLRP3 deficiency protects the macrophages from the necrosis.Furthermore,necrotic inhibitors or even pan-caspase inhibitor alone does not or only partly inhibit such necrosis.Instead,a combination of inhibitors composed of pan-caspase inhibitor IDN-6556,RIPK3 inhibitor GSK′872 and NADPH oxidase inhibitor GKT137831 not only markedly inhibits the necrosis,with all apoptotic and pyroptotic pathways being blocked,but also attenuates gossypol-induced peritonitis in mice.Lastly,the activation of the NLRP3 pathway and apoptotic caspase-3 appears to be independent of each other.Collectively,gossypol simultaneously induces the activation of multiple subroutines of regulated necrosis in macrophages depending on both apoptotic and inflammatory caspases. | Meiyan Zhong Yuanting Huang Bo Zeng Lihui Xu Chunsu Zhong Jiahao Qiu Xunjia Ye Mingye Chen Bo Hu Dongyun Ouyang Xianhui He | 2022 | Acta Biochimica et Biophysica Sinica2022，54，1： | 0 |
| 19 | China Takes Initiative in Relations with Latin America显示文摘NEW trends unfolded in China’s stable relationships with Latin American countries in the year 2012,apparent in more diversified economic and trade cooperation.China’s proactive application of its strategies in the region has brought about greater global interaction.Achieving common trust and understanding,however,entails greater cultural and educational exchanges. | CHEN YUANTING | 2013 | China Today2013，62，1： | 0 |
| 20 | Look at the Direction of US-Latin America Relations from Bush’s Visit to Latin America显示文摘From March 8th to 14th, 2007, US President George W. Bush paid an visit to five Latin American states of Brazil, Uruguay, Colombia, Guatemala and Mexico. This visit, with the largest number of Latin American states visited and the longest duration since Bush came to office, was an important diplomatic move that demonstrates the US's determination to regain its 'backyard' as well as major policy adjustments of the US towards Latin America. | Chen Yuanting Shi Dongmei | 2007 | International Understanding2007，，2： | 0 |
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