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| 1 | Trends and Challenges for Population and Health During Population Aging——China,2015-2050显示文摘Summary What is already known about this topic?As the largest country in the world,China experienced a demographic transition at a historic scale during the past 50 years with extraordinarily associated changes in the age structure of the population,declining fertility rates,accelerating process of population aging,and growing population scale. | Yanan Luo Binbin Su Xiaoying Zheng | 2021 | China CDC weekly2021，3，28： | 61 |
| 2 | Study of Furoxan Derivatives for Energetic Applications显示文摘二新奇精力充沛的混合物, 3,4 二度(1,2,4-triazole-3-yl ) furoxan (BTAF ) 和 3,4 二度(1-nitro-1,2,4-triazole-3-yl ) furoxan (BNTAF ) ,被准备,他们的结构被红外, 1H NMR, 13C NMR, MS 技术和元素的分析描绘。BTAF 和 BNTAF 的性质被估计。BTAF 的预言的性能数据如下:密度(测量) 是 1.75 g/cm3,氮内容 50.9% ,形成 +419.7 kJ/mol 的爆炸速度 7277 m/s,爆炸压力 20.1 GPa 和热含量。BNTAF 的预言的表演数据如下:密度是 1.84 g/cm3,氮内容 45.2% ,形成 +841.5 kJ/mol,爆炸速度 8490 m/s 和爆炸压力的热含量 32.4 GPa。BTAF 和 BNTAF 的主要 themal 性质被 DSC 和 TG 技术分析,结果证明 BTAF 在 188.8 攠桸扩瑩摥栠杩 ? 敳敬瑣癩瑩 ? 湡 ? 湡楴楤瑳牵慢据 ? 潦 ? 敆 ? 愠潭杮攠癮物湯敭瑮污祬爠汥癥湡 ? 敭慴? 潩獮椠 ? 煡敵畯 ? 与伴随物分解融化敭楤? 吠敨洠瑥潨 ? 景 ? 扯猧瀠潬 ? 湩楤慣整 ? 桴 ? 潦浲瑡潩 ? 景ㄠ呼挠浯汰硥戠瑥敷湥 ? 愠摮吗?? | Yanan Li Zhizhong Zhang Zhongxue Ge BozhouWang Weipeng Lai Yifen Luo | 2013 | Chinese Journal of Chemistry2013，31，4： | 10 |
| 3 | TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness显示文摘TGF-β-induced factor homeobox 2(TGIF2)is a transcription regulator that plays essential roles in the regulation of development and cell fate decisions.Aberrant expression of TGIF family proteins has been observed in several cancers,including ovarian,esophageal,and colorectal cancers.Here,we report that TGIF2 mediates the EGFR–RAS–ERK signaling pathway to enhance the stemness of lung adenocarcinoma(LUAD)cells and,therefore,promote the progression and metastasis of LUAD.We found that high TGIF2 expression was closely correlated with tumor growth,lymph node metastasis,and survival of patients with LUAD.Mice bearing TGIF2-silenced H1299 xenografts developed smaller tumors and fewer lung metastases.Importantly,silencing TGIF2 decreased the cancer stem cell(CSC)-like properties in A549 and H1299 cells.Furthermore,we identified that TGIF2 binding to the OCT4 promoter promotes its expression.In both LUAD cells and in vivo LUAD mouse models,we revealed that EGFR–RAS–ERK signaling phosphorylated TGIF2 and increased its stability,which was important for TGIF2-promoted LUAD stemness since phosphorylation-deficient TGIF2 mutants lost these functions.Thus,our study revealed that an important factor,TGIF2,bridges EGFR signaling to the CSC characteristics of LUAD cells,which can be utilized as an effective target for LUAD therapy. | Renle Du Wenzhi Shen Yi Liu Wenjuan Gao Wei Zhou Jun Li Shuangtao Zhao Chong Chen Yanan Chen Yanhua Liu Peiqing Sun Rong Xiang Yi Shi Yunping Luo | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 7 |
| 4 | Orthogonal design to sift the optimal parameter of Neiguan acupuncture for cerebral infarction显示文摘The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture,but have also affected the specificity of acupoints.The present study used instruments to control needle depth,lifting and thrusting frequency,and the duration of acupuncture.Effects of the quantified acupuncture were observed at Neiguan(PC6)with different stimulation parameters.A frequency of 1,2,or 3 Hz and duration of 5,60,or 180 seconds were used to observe cerebral blood flow and ratio of infarct volume recovery.Results showed that stimulation at Neiguan with a frequency of 1 Hz and long duration of 180 seconds or 2/3 Hz and long duration of 5/60seconds significantly increased cerebral blood flow and decreased the ratio of infarct volume.Interactions between frequency and duration play a critical role in quantified acupuncture therapy. | Yanan Zhang Sha Yang Xiaonong Fan Shu Wang Nina He Lingxin Li Ding Luo Xuemin Shi | 2013 | Neural Regeneration Research2013，8，28： | 7 |
| 5 | Micro RNA profiles and potential regulatory pattern during the early stage of spermatogenesis in mice显示文摘Spermatogenesis is a complicated and poorly understood process that relies on the precise regulation of the self-renewal and differentiation of spermatogonia. In many organisms, micro RNAs(mi RNAs) are involved in multiple developmental processes as critical regulators of transcriptional and post-transcriptional gene silencing. This study investigated the expression pattern of mi RNAs in type B spermatogonia cells(BSc) and primary spermatocytes(PSc) of mice, using a high-throughput small RNA sequencing system. The results revealed that the expression levels of Let-7 family mi RNAs were remarkably high in both cell types. Furthermore, the expression levels of mi R-21, mi R-140-3p, mi R-103, mi R-30 a, mi R-101 b and mi R-99 b were decreased during the transformation from BSc to PSc. These mi RNAs target vital genes that participate in apoptosis, cell proliferation and differentiation, junction assembly and cell cycle regulation. These results highlight the indispensable role of mi RNAs in spermatogenesis. | LUO MengMeng HAO LiLi HU Fen DONG YaNan GOU LiXia ZHANG WenDian WANG Xin ZHAO YuHui JIA MengChun HU SongNian ZHANG XiuJun | 2015 | Science China(Life Sciences)2015，58，5： | 6 |
| 6 | Synthesis, Structure and Properties of Two New Coordination Polymers Based on 4-[(8-Hydroxy-5-quinolinyl)azo]-benzenesulfonic Acid显示文摘 | LUO Yanan XU Xianzhu SUN Fuxing YU Xiaoyang ZHANG Xiao ZHANG Ting YU Liying | 2014 | Chemical Research in Chinese Universities2014，30，1： | 4 |
| 7 | A 5.4mW and 6.1% efficiency fixed-tuned 214GHz frequency doubler with Schottky barrier diodes显示文摘A Y-band frequency doubler is analyzed and designed with GaAs planar Schottky diode,which is flip-chip solded into a 50|xm thick quartz substrate.Diode embedding impedance is found by fullwave analysis with lumped port to model the nonlinear junction for impedance matching without the need of diode equivalent circuit model.All the matching circuit is designed 'on-chip' and the multiplier is self-biasing.To the doubler,a conversion efficiency of 6.1%and output power of 5.4mW are measured at 214 GHz with input power of 88 mW,and the typical measured efficiency is 4.5%in200~225GHz. | 姚常飞 Zhou Ming Luo Yunsheng Kou Yanan Li Jiao | 2015 | High Technology Letters2015，21，1： | 4 |
| 8 | Developmental Gerontology and Active Population Aging in China显示文摘Population aging is an irreversible process in the development of modern society,which brings challenges to comprehensive modernized social governance.Population aging is a“dualistic”development issue that not only leads to aging of the labor force structure but also creates new demographic dividends.This study describes the core thoughts of developmental gerontology(DG),which provides new insight into the relationship between active aging and comprehensive governance for modernized society.The development of DG will provide a feasible and sustainable path to integrate and coordinate the relationship between population aging,society,and economy. | Xiaoying Zheng Yanan Luo Binbin Su Ping He Chao Guo Yaohua Tian Shasha Han Chen Chen Yiran Wang Jufen Liu Jun Li | 2023 | China CDC weekly2023，5，8： | 4 |
| 9 | Comprehensive strategy of conduit guidance combined with VEGF producing Schwann cells accelerates peripheral nerve repair显示文摘Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment.Since local delivery of VEGF-A in peripheral nerve repair is expected to promote angiogenesis in the microenvironment and Schwann cells(SCs)play critical role in nerve repair,combination of VEGF and Schwann cells may lead to efficient peripheral nerve regeneration.VEGF-A overexpressing Schwann cells were established and loaded into the inner wall of hydroxyethyl cellulose/soy protein isolate/polyaniline sponge(HSPS)conduits.When HSPS is mechanically distorted,it still has high durability of strain strength,thus,can accommodate unexpected strain of nerve tissues in motion.A 10 mm nerve defect rat model was used to test the repair performance of the HSPS-SC(VEGF)conduits,meanwhile the HSPS,HSPS-SC,HSPS-VEGF conduits and autografts were worked as controls.The immunofluorescent co-staining of GFP/VEGF-A,Ki67 and MBP showed that the VEGF-A overexpressing Schwann cells could promote the proliferation,migration and differentiation of Schwann cells as the VEGF-A was secreted from the VEGF-A overexpressing Schwann cells.The nerve repair performance of the multifunctional and flexible conduits was examined though rat behavioristics,electrophysiology,nerve innervation to gastrocnemius muscle(GM),toluidine blue(TB)staining,transmission electron microscopy(TEM)and NF200/S100 double staining in the regenerated nerve.The results displayed that the effects on the repair of peripheral nerves in HSPS-SC(VEGF)group was the best among the conduits groups and closed to autografts.HSPS-SC(VEGF)group exhibited notably increased CD31+endothelial cells and activation of VEGFR2/ERK signaling pathway in the regenerated nerve tissues,which probably contributed to the improved nerve regeneration.Altogether,the comprehensive strategy including VEGF overexpressing Schwann cells-mediated and HSPS conduit-guided peripheral nerve repair provides a new avenue for nerve tissue engineering. | Ping Wu Zan Tong Lihua Luo Yanan Zhao Feixiang Chen Yinping Li Céline Huselstein Qifa Ye Qingsong Ye Yun Chen | 2021 | Bioactive Materials2021，6，10： | 4 |
| 10 | Changes of intracellular Ca2+ in quercetin-inducec autophagy progression显示文摘 | Xiaodong Cui Yanan Luo Chen Li Yuying Li Zhuanhua Wang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，11： | 3 |
| 11 | Dual-metal atoms embedded into two-dimensional covalent organic framework as efficient electrocatalysts for oxygen evolution reaction:A DFT study显示文摘The electrochemical oxygen evolution reaction(OER)is a half-reaction of water-splitting for hydrogen generation,yet suffers from its sluggish kinetics and large overpotential.It is highly desirable to develop efficient and stable OER electrocatalysts for the advancement of water-splitting.Herein,by means of density functional theory(DFT)calculations,we systematically investigated a series of two-dimensional(2D)dual-atom catalysts(DACs)on a novel synthesized covalent organic framework(COF)material as potential efficient catalysts toward the OER.The designed 6 homonuclear(2TM-COF)and 15 heteronuclear(TM1TM2-COF)DACs all exhibit good stability.There is a strong scaling relationship between the adsorption Gibbs free energies of HO*and HOO*intermediates,and the OER overpotential(η^(OER))volcano curve can be plotted as a function ofΔGO*−ΔGHO*.RhIr-COF shows the best OER catalytic activity with aη^(OER)value of 0.29 V,followed by CoNi-COF(0.33 V),RuRh-COF(0.34 V),and NiIrCOF(0.37 V).These four OER DACs exhibit lower onset potential and higher current density than that of the IrO2(110)benchmark catalyst.Aided by the descriptor identification study,the Bader charge that correlated with the Pauling electronegativity of the embedded dual-metal atoms was found to be the most important factor governing the catalytic activity of the OER.Our work highlights a potentially efficient class of 2D COF-based DACs toward the OER. | Yanan Zhou Lanlan Chen Li Sheng Qiquan Luo Wenhua Zhang Jinlong Yang | 2022 | Nano Research2022，15，9： | 2 |
| 12 | Layered Double Hydroxides Derived ZnO-Al2O3 Supported Pd-Ag Catalysts for Selective Hydrogenation of Acetylene显示文摘ZnO-Al 2 从分层的双氢氧化物(ZnAl-LDH ) 导出的 O 3 成功地被申请为到乙烯和 Pd-Ag/ZnO-Al 2 O 3 催化剂在准备样品之中显示出最好的催化表演。这被发现 ZnO-Al 2 O 3 金属氧化物导出形式 ZnAl-LDH 能显著地压制乙炔的在加氢上获得乙烯的相对更高的选择。因为 oligomerization 反应, Ag 的介绍高效地限制了焦炭的形成,它被热 gravimetric 分析进一步证实。向乙烯的选择在 Pd-Ag/ZnO-Al 2 O 3> Pd/ZnO-Al 2 O 3> Pd-Ag/Al 2 O 3> Pd/Al 2 在高变换水平的 O 3 。作为热 gravimetric 和揭示的微分温度分析(TG-DTA ) , ZnO-Al 2 O 3 支持显示出更少的焦炭形成。 | Xiaoping Gao Yanan Zhou Fangli Jing Jingjie Luo Qingsong Huang Wei Chu | 2017 | Chinese Journal of Chemistry2017，35，6： | 2 |
| 13 | Trends and Challenges for Population Health and Migration-China,2015−2050显示文摘What is already known about this topic?Along with the quick change of society and health transformation,as well as the continued expansion of urbanization,the health risk and its variation of migrants in China would became more complicated.What is added by this report?Although a decreasing net migration flow trend was presented from 2015 to 2050,an increasing pace of aging and younger-age trend of migrants would pose serious challenges for population health in China.Deepening aging trend of migrants contributes to the increment of the disease burden of non-communicable diseases(NCDs)and disabilities,and the upward trend of young-age migrant patients with infectious diseases remain a threat to the future intervention and prevention of infectious diseases.What are the implications for public health practice?Health policies to eliminate the adverse effects of migration on population health should pay more attention to meet the health care demands of highly vulnerable migrant populations,such as very older and very young migrants. | Yanan Luo Chao Guo Yiran Wang Xiaoying Zheng | 2020 | China CDC weekly2020，2，28： | 2 |
| 14 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 15 | Effect of agitation on the characteristics of air dense medium fluidization显示文摘In order to study the effect of agitation on the characteristics of air dense medium fluidization, we designed and constructed an agitation device. Analyses were then conducted on the fluidization characteristics curves, the bed density stability and the average bubble rise velocity Uaunder different agitation conditions. The results indicated that a lower bed pressure drop(without considering lower gas velocity in a fixed bed stage) and higher minimum fluidized velocity are achieved with increasing agitation speed.The height d(distance between the lower blades and air distribution plate) at which the agitation paddle was located had a considerable effect on the stability of the bed density at 9.36 cm/s < U < 10.70 cm/s. The higher the value of d, the better the stability, and the standard deviation of the bed density fluctuation r dropped to 0.0364 g/cm^3 at the ideal condition of d = 40 mm. The agitation speed also had a significant influence on the fluidization performance, and r was only 0.0286 g/cm^3 at an agitation speed of N = 75 r/min. The average bubble rise velocity decreased significantly with increasing agitation speed under the operating condition of 1.50 cm/s < U–U_(mf)< 3.50 cm/s. This shows that appropriate agitation contributes to a significant improvement in the fluidization quality in a fluidized bed, and enhances the separation performance of a fluidized bed. | Wang Yanan Luo Zhenfu Huang Ge Ren Baojin | 2016 | International Journal of Mining Science and Technology2016，26，3： | 2 |
| 16 | Catalyst-Free In Situ Carbon Nanotube Growth in Confined Space via High Temperature Gradient显示文摘Carbonaceous materials,such as graphite,carbon nanotubes(CNTs),and graphene,are in high demand for a broad range of applications,including batteries,capacitors,and composite materials.Studies on the transformation between diferent types of carbon,especially from abundant and low-cost carbon to high-end carbon allotropes,have received surging interest.Here,we report that,without a catalyst or an external carbon source,biomass-derived amorphous carbon and defective reduced graphene oxide(RGO)can be quickly transformed into CNTs in highly confned spaces by high temperature Joule heating.Combined with experimental measurements and molecular dynamics simulations,we propose that Joule heating induces a high local temperature at defect sites due to the corresponding high local resistance.Te resultant temperature gradient in amorphous carbon or RGO drives the migration of carbon atoms and promotes the growth of CNTs without using a catalyst or external carbon source.Our fndings on the growth of CNTs in confned spaces by fast high temperature Joule heating shed light on the controlled transition between diferent carbon allotropes,which can be extended to the growth of other high aspect ratio nanomaterials. | Chaoji Chen Yanan Chen Shuze Zhu Jiaqi Dai Glenn Pastel Yonggang Yao Dapeng Liu Yanbin Wang Jiayu Wan Teng Li Wei Luo Liangbing Hu | 2018 | Research2018，，1： | 2 |
| 17 | Recycle spent graphite to defect-engineered,high-power graphite anode显示文摘Graphite is a dominant anode material for lithium-ion batteries(LIBs)due to its outstanding electrochemical performance.However,slow lithium ion(Li+)kinetics of graphite anode restricts its further application.Herein,we report that high-temperature shock(HTS)can drive spent graphite(SG)into defect-rich recycled graphite(DRG)which is ideal for high-rate anode.The DRG exhibits the charging specific capacity of 323 mAh/g at a high current density of 2 C,which outperforms commercial graphite(CG,120 mAh/g).The eminent electrochemical performance of DRG can be attributed to the recovery of layered structure and partial remaining defects of SG during ultrafast heating and cooling process,which can effectively reduce total strain energy,accelerate the phase transition in thermodynamics and improve the Li+diffusion.This study provides a facile strategy to guide the re-graphitization of SG and design high performance battery electrode materials by defect engineering from the atomic level. | Jiawei Luo Jingchao Zhang Zhaoxin Guo Zhedong Liu Shuming Dou Wei-Di Liu Yanan Chen Wenbin Hu | 2023 | Nano Research2023，16，4： | 2 |
| 18 | Nucleon-pair shell model : The effects of the SD pair structure on collectivity of low-lying states显示文摘 | Chen Jianquan Luo Yanan | 1998 | Nucl Phys A1998，639，： | 1 |
| 19 | Preparation techniques of metal clad fibres for corrosion monitoring of steel materials显示文摘 | Peng Gangding Luo Yanan | 2007 | Smart Materials and Structure2007，16，3： | 1 |
| 20 | Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice显示文摘-secretase 建筑群催化淀粉的蛋白质先锋应用软件的最后的劈开步产生淀粉的 A 肽,在 Alzheimer 的疾病广告病人的大脑的老年的匾的一个病原的部件。最近的研究显示出那 presenilin enhancer-2 1 是的 Pen-2, presenilin PS,包括的 PS1 和 PS2, nicastrin,和前面的咽有缺陷者 -secretase 的必要部件。在 vitro 的 Pen-2 的结构和功能是明确的。然而,很少在广告模型老鼠的中央神经系统 CNS 对 Pen-2 的神经解剖学的分发和表示被知道。我们这里报导,用象染色的 immunohistochemical 和 immunoblotting 那样的各种各样的方法,那 Pen-2 广泛地在广告模型老鼠在主要区域的特定的 neuronal 房间被表示包括嗅觉的灯泡,基础前脑, striatum ,外皮,马头鱼尾的怪兽,杏仁之类,丘脑,视下丘,小脑, brainstem ,并且针的绳索。它在老鼠大脑在特定的 neuronal 房间与 PS1 被共同表示。Pen-2 比细胞外的淀粉的存款广泛地更分布式,建议在局部性的淀粉的免职的另外的因素的重要性。Pen-2 在成年广告鼠标在房间膜和 cytoplasma 主要是局部性的,但是仅仅在控制在房间膜散布。在出生后的开发的早阶段, Pen-2 的表达式水平在 CNS 相对高,但是在成年鼠标逐渐地衰退。现在的学习作为一个关键部件为 Pen-2 提供一个解剖基础在发展和成年老鼠的大脑复杂的 -secretase,和 Pen-2 可能是仔细与在老化的负担有关神经系统。 | Yanan Chu Xuehua Peng Zhiming Long Kejian Wang Shifang Luo Akhilesh Sharma Guiqiong He | 2015 | Acta Biochimica et Biophysica Sinica2015，47，4： | 1 |
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