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| 1 | Urban Construction Land Suitability Evaluation Based on Improved Multi-criteria Evaluation Based on GIS(MCE-GIS): Case of New Hefei City,China显示文摘Urban construction land suitability evaluation(UCLSE)is a complex system engineering and the basis for rational use of the limited urban land resources in China.It has an important practical value on urban construction land use planning and management from the angle of methodology.As a widely used technique,traditional multi-criteria evaluation based on GIS(MCE-GIS),is not suitable for UCLSE.This study develops an improved MCE-GIS method which could be more suitable for UCLSE based on urban complex ecological system theory and the summary of the shortcomings of traditional MCE-GIS.The improvements include three aspects:a composite evaluation index system rather than natural indexes alone,an index weight calculated by using fuzzy Analytic Hierarchy Process(AHP)method rather than the common AHP method,and the integrated overlay rule,which includes selecting the minimum value,weighted linear combination(WLC)and simple summation.The main advantage of this improved technique is that it can make UCLSE more comprehensive,more operational and more reasonable.It can provide a scientific basis for decision making in the planning and management of urban construction land use.The improved MCE-GIS system has been adopted in the New Hefei City,Anhui Province,China.Based on the results of UCLSE in New Hefei,three functional areas including construction-appropriate areas,construction-restricted areas and construction-forbidden areas could be worked out,in which 36.90%of the total study area could be developed as urban construction land and the remaining 63.10%should be protected as reserves land or as ecological land.Furthermore,the results can provide scientific decision support for spatial planning and eco-environment protection in New Hefei. | ZHANG Xiaorui FANG Chuanglin WANG Zhenbo MA Haitao | 2013 | Chinese Geographical Science2013，23，6： | 18 |
| 2 | Generation of B Cell-Deficient Pigs by Highly Efficient CRISPR/Cas9-Mediated Gene Targeting显示文摘Generating B cell-deficient mutant is the first step to produce human antibody repertoires in large animal models. In this study, we applied the clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated(Cas) system to target the JHregion of the pig Ig M heavy chain gene which is crucial for B cell development and differentiation. Transfection of Ig M-targeting Cas9 plasmid in primary porcine fetal fibroblasts(PFFs) enabled inducing gene knock out(KO) in up to 53.3% of colonies analyzed, a quarter of which harbored biallelic modification, which was much higher than that of the traditional homologous recombination(HR). With the aid of somatic cell nuclear transfer(SCNT) technology, three piglets with the biallelic Ig M heavy chain gene mutation were produced. The piglets showed no antibody-producing B cells which indicated that the biallelic mutation of the Ig M heavy chain gene effectively knocked out the function of the Ig M and resulted in a B cell-deficient phenotype. Our study suggests that the CRISPR/Cas9 system combined with SCNT technology is an efficient genome-editing approach in pigs. | Fengjiao Chen Ying Wang Yilin Yuan Wei Zhang Zijian Ren Yong Jin Xiaorui Liu Qiang Xiong Qin Chen Manling Zhang Xiaokang Li Lihua Zhao Ze Li Zhaoqiang Wu Yanfei Zhang Feifei Hu Juan Huang Rongfeng Li Yifan Dai | 2015 | Journal of Genetics and Genomics2015，42，8： | 15 |
| 3 | Physical characteristics of Chinese Hakka显示文摘Using standard and internationally validated methods,86 anthropologic characteristics were determined in 650 male(305 from urban areas and 345 from rural areas) and 704 female(331 from urban areas,373 from rural areas) Chinese Hakka adults living in Guangdong and Jiangxi.The data were used to calculate 24 anthropologic indices,which were analyzed statistically.The physical characteristics of Hakka subjects were analyzed and compared with reference ethnic data.There were four main findings of this study.First,a small proportion of Hakka adults had an eye fold on the upper eyelid,but a large proportion had a mongoloid fold.The eye slits were narrow in most adults,had a medium nasal root height and straight bridges,and most of the external angles were prominent.The nasal base was upturned in most men.The distributions of the three types of nasal base in women were similar.The proportions of subjects with middle and high alae nasi heights were high and similar.Males with a maximum nostril diameter were mostly classified as transverse and oblique,while many women were classified as transverse and had relatively wide alae nasi.The round lobe type was the most common.Upper lip skin height was mostly classified as medium.Lips were classified as thin.The hair was black,eyes were brown,and the skin was yellowish.Second,the head length was long in male Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Meanwhile,head breadth,morphological facial height,nose breadth,mouth breadth,and nose height were similar to those of South-Asian populations.Head length was long in female Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Head breadth,nose breadth,and mouth breadth were similar to those of South-Asian populations.Third,the stature of male and female Hakka in urban and rural areas was classified as medium.The proportions of male and female Hakka classified as mesocephaly(length-breadth index of the head),hypsicephalic type,metriocephalic type(breadth-height index of the head) mesorrhiny,long trunk,subbrachyskelic type,broad shoulder breadth,and narrow distance between iliac crests were higher than those of other types.Finally,principal component analyses showed that the physical characteristics of Hakka were between those of South-Asian and North-Asian ethnic populations,but were generally closer to those of North-Asian populations in China. | ZHENG LianBin LI YongLan LU ShunHua BAO JinPing WANG Yang ZHANG XiaoRui XUE Hong RONG WenGuo | 2013 | Science China(Life Sciences)2013，56，6： | 13 |
| 4 | Mutual effects of nitric oxide and iron on the growth of marine algae显示文摘Experiments on the effects of nitric oxide (NO) and iron on the growth of marine microalgae Skeletonema costatum were conducted. The results are as follows: exogenous NO could increase the growth rate of marine algae and raise the biomass remarkably under iron-deficient conditions. But it was a complicated process that the phytoplankton growth was influenced by NO and iron, which was controlled by the NO concentration, the nutrition level of the culture medium and the iron concentration, etc. Meanwhile, the iron concentration in the medium also has a direct influence on the growth and NO release capacity of the algae. Therefore, the effects of NO and iron on the growth of marine phytoplankton were mutual. | LIU Chunying ZHANG Zhengbin CHEN Xiaorui | 2005 | Acta Oceanologica Sinica2005，24，5： | 11 |
| 5 | Hierarchical assembly of highly efficient visible-light-driven Ag/g-C_(3)N_(4)/kaolinite composite photocatalyst for the degradation of ibuprofen显示文摘A novel Ag/g-C_(3)N_(4)/kaolinite composite photocatalyst was fabricated for the first time through a two-step assembly strategy by employing in situ calcination and a photodeposition process.The synthesized Ag/g-C_(3)N_(4)/kaolinite composite reached a higher degradation rate of ibuprofen(IBP)with a reaction rate constant of 0.0113 min^(-1) at an Ag content of 7% under visible-light irradiation,which was approximately 1.87 times that of the Ag/g-C_(3)N_(4) composite.Based on the physicochemical properties,the enhanced photocatalytic activity was attributed to the stronger adsorption property,wider photoresponse range and more efficient separation and transfer of electron-hole pairs.Furthermore,the incorporation of monodispersed Ag nanoparticles onto the g-C_(3)N_(4)/kaolinite sheets provided more reactive sites for the IBP degradation.In addition,according to the EPR study and trapping experiments,it was demonstrated that holes(h^(+))should be the key reactive species.A possible pathway of IBP degradation was also proposed based on the detected intermediates.Overall,the results of this work may facilitate the design of a novel visible-light-driven photocatalyst with a high efficiency that is derived from a natural mineral for environmental remediation. | Zhiming Sun Xiangwei Zhang Xiongbo Dong Xiaorui Liu Ye Tan Fang Yuan Shuilin Zheng Chunquan Li | 2020 | Journal of Materiomics2020，6，3： | 8 |
| 6 | Analyses of circRNA profiling during the development from pre-receptive to receptive phases in the goat endometrium显示文摘Background: Recent studies have revealed that noncoding RNAs play important regulatory roles in the formation of endometrial receptivity.Circular RNAs(circRNAs) are a universally expressed noncoding RNA species that have been recently proposed to act as miRNA sponges that directly regulate expression of target genes or parental genes.Results: We used Illumina Solexa technology to analyze the expression profiles of circRNAs in the endometrium from three goats at gestational day 5(pre-receptive endometrium,PE) and three goats at gestational day 15(receptive endometrium,RE).Overall,21,813 circRNAs were identified,of which 5,925 circRNAs were specific to the RE and 9,078 were specific to the PE,which suggested high stage-specificity.Further analysis found 334 differentially expressed circRNAs in the RE compared with PE(P < 0.05).The analysis of the circRNA-miRNA interaction network further supported the idea that circRNAs act as miRNA sponges to regulate gene expression.Moreover,some circRNAs were regulated by estrogen(E2)/progesterone(P4) in endometrial epithelium cell lines(EECs) and endometrial stromal cell line(ESCs),and each circRNA molecule exhibited unique regulation characteristics with respect to E2 and P4.Conclusions: These data provide an endometrium circRNA expression atlas corresponding to the biology of the goat receptive endometrium during embryo implantation. | Yuxuan Song Lei Zhang Xiaorui Liu Mengxiao Niu Jiuzeng Cui Sicheng Che Yuexia Liu Xiaopeng An Binyun Cao | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 8 |
| 7 | National 2000' GPS control network of China显示文摘有超过 2500 个车站的一个精确地统一的国家 GPS 网络,说出“国家 2000' GPS 控制 Netweork ”,签署了时代 2000.0,被集成存在建立了中国的六个全国性的 GPS 网络与不同目的由不同部门建立了。这篇论文论述令人激动的 GPS 网络的特征,在 GPS 网络,包括的功能的模型,随机的模型以及调整的综合调整总结策略原则修正。由根据存在 GPS 网络并且在 IGS 车站的支持下面的特征修改调整策略,综合国家 GPS 网络的精确性极大地被改进。在潜水艇网络之中的资料差别消失,系统的错误影响被削弱,并且估计的坐标和他们的变化上的孤立点的效果被控制。为水平部件的平均标准差当时更小,这被显示出 1.0 厘米,垂直部件比 2.0 厘米小,并且三维(3-D ) geocenter 坐标的位置比 3.0 厘米小。为 3-D 位置的外面的检查精确性比 1.0 厘米平均好。 | Yang Yuanxi Tang Yingzhe Chen Chuanlu Wang Min Zhang Peng Wang Xiaorui Song Lijie Zhang Zusheng | 2007 | Progress in Natural Science:Materials International2007，17，8： | 7 |
| 8 | Correlation Research between Turbulent Pressure Pulsation and Internal Sound Field Characteristics of Centrifugal Pump显示文摘In order to study the correlation between the internal flow noise of the centrifugal pump and the turbulent pressure pulsation,a single-stage single-suction centrifugal pump was used as the research object by the combination of numerical calculation and experiment.Based on the RNG k-?model and the N-S equation,the model pump was simulated numerically by CFD.A dipole sound source was extracted by the turbulent pulse action of the volute wall surface according to the FW-H equation.The acoustic field of the model pump was solved on the basis of the boundary element method,and the sound pressure distribution of the internal flow field under the action of the dipole sound source of the volute wall and the frequency response of the inlet and outlet fields were obtained.The results show that the distribution of hydrodynamic noise inside the centrifugal pump is related to the pressure pulsation,presenting obvious dipole distribution and disturbance at the tongue.The sound pressure value of the field is mainly concentrated in the blade passing frequency and double frequency,in which the blade passing frequency is the strongest,and the sound pressure value decreases obviously under other double frequency.The main frequency of hydrodynamic noise is the blade passing frequency. | CHENG Xiaorui WANG Peng ZHANG Shuyan | 2021 | Journal of Thermal Science2021，30，1： | 5 |
| 9 | Novel Wx alleles generated by base editing for improvement of rice grain quality显示文摘Amylose content(AC),which is regulated by the Waxy(Wx)gene,is a major indicator of eating and cooking quality(ECQ)in rice(Oryza sativa).Thus far,only a limited number of mutations in the N-terminal domain of Wx were found to have a major impact on the AC of rice grains and no mutations with such effects were reported for other regions of the Wx protein.Here,nucleotide substitutions in the middle region of Wx were generated by adenine and cytosine base editors.The nucleotide substitutions led to changes in 15 amino acid residues of Wx,and a series of novel Wx alleles with ACs of 0.3%-29.43%(wild type with AC of 19.87%)were obtained.Importantly,the waxy~(abe2)allele showed a'soft rice'AC,improved ECQ,favorable appearance,and no undesirable agronomic traits.The transgenes were removed from the waxy~(abe2)progeny,generating a promising breeding material for improving rice grain quality. | Xiaorui Huang Fei Su Sheng Huang Fating Mei Xiaomu Niu Changle Ma Hui Zhang Xiaoguo Zhu Jian-Kang Zhu Jinshan Zhang | 2021 | Journal of Integrative Plant Biology2021，63，9： | 4 |
| 10 | Speed control strategy for tractor assisted driving based on chassis dynamometer test显示文摘Realizing automation of the chassis dynamometer and the unmanned test workshop is an inevitable trend in the development of new tractor products.The accuracy of the speed control of the test tractor directly affects the accuracy of the test loading force.In order to meet the purpose of precise control of the test tractor speed on the chassis dynamometer,a fuzzy PID control strategy was developed according to the working principle of assisted driving.On the basis of traditional PID control,the parameters of fuzzy inference module were added for real-time adjustment to achieve faster response to tractor speed changes and more precise control of tractor speed.The Matlab-Cruise co-simulation platform was established for simulation,and the experiment was verified by the tractor chassis dynamometer using the NEDC working condition and tractor ploughing working condition.The results show that both PID control and fuzzy PID control can achieve tractor speed following accuracy of±0.5 km/h.Fuzzy PID control has higher tractor speed following accuracy,faster response when speed changes,less tractor speed fluctuation,and overall control effect is better than PID control.The research results can provide a reference for the realization of the chassis dynamometer unmanned test workshop. | Xiaorui Zhang Zhili Zhou | 2021 | International Journal of Agricultural and Biological Engineering2021，14，6： | 4 |
| 11 | Matrix metaHoproteinase-8 inhibitors mitigate sepsis-induced myocardial injury in rats显示文摘 | Zhou Xiaorui Lu Jiakai Chen Dong Wang Wei Cai Qing Li Tongxun Zhang Jinglan | 2014 | Chinese Medical Journal2014，，8： | 3 |
| 12 | Wetting behavior and interfacial characteristic of Sn-Ag-Cu solder alloy on Cu substrate显示文摘Wettability of molten Sn-Ag-Cu alloy on Cu substrate has been determined by sessile drop method, as well as its dependence on time and temperature. It was found that the evolution of contact angle at the alloy’s melting point experienced four different stages. Especially, the contact angle was unstable and fluctuant in stage II, and gradually decreased in stage III mainly due to a chemical reaction between Sn-Ag-Cu alloy and Cu substrate. The contact angle decreased with increasing temperature, but increased slightly at 629 K, for another chemical reaction occurred. Interfacial characteristic has been further investigated by examining the sample’s cross section. Intermetallic compounds of Cu6Sn5 and β-Sn phase were found at the interface of Sn-Ag-Cu/Cu. | ZHANG XiaoRui YUAN ZhangFu ZHAO HongXin ZANG LiKun LI JianQiang | 2010 | Chinese Science Bulletin2010，55，9： | 3 |
| 13 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 14 | Rapid,visual,and equipment-free point-of-care testing for Staphylococcus aureus by direct recombinase polymerase amplification with SYBR GreenΙ显示文摘Food-borne diseases mainly caused by bacterial pathogens and the safety of genetically modified(GM)food have become global concerns[1].As a leading bacterial pathogen,Staphylococcus aureus can not only cause a variety of diseases[2]but also contaminate different kinds of animal food products[3].In addition,GM foods whose impact on human health and the natural environment is still a matter of controversy have gradually entered the commercial markets[4].Therefore,many countries have decided to implement labeling regulations for authorized genetically modified organisms(GMOs)to protect the consumers’right to know[5].Hence,it is critical to develop a rapid,simple,equipment-free,and on-site testing method to detect the GM contents in food samples and pathogen to ensure food safety. | Xiaorui Fan Fangti Han Binan Zhao Yan Xu Xiao Zhao Xinyi Pu Yanan Du Qi Zhang Xiaoxia Zhang Wanjing Zhang Wenjing Wu Zhiwei Chen Kai Zhao | 2021 | Acta Biochimica et Biophysica Sinica2021，53，9： | 3 |
| 15 | Flexible and biocompatible nanopaper-based electrode arrays for neural activity recording显示文摘 | Yichuan Guo Zhiqiang Fang Mingde Du Long Yang Leihou Shao Xiaorui Zhang Li Li Jidong Shi Jinsong Tao Jinfen Wang Hongbian Li Ying Fang | 2018 | Nano Research2018，11，10： | 3 |
| 16 | Evolution and functional analysis of the Pif97 gene of the Pacific oyster Crassostrea gigas显示文摘 | Xiaotong WANG Xiaorui SONG Tong WANG Qihui ZHU Guoying MIAO Yuanxin CHEN Xiaodong FANG Huayong QUE Li LI Guofan ZHANG | 2013 | Current Zoology2013，59，1： | 3 |
| 17 | Enhanced visible-light-assisted peroxymonosulfate activation over MnFe_(2)O_(4) modified g-C_(3)N_(4)/diatomite composite for bisphenol A degradation显示文摘The MnFe_(2) O_(4)/g-C_(3) N_(4)/diatomite composites(Mn/G/D) were prepared via a facile precipitation-calcination method in this study.The Mn/G/D possessed higher specific surface area,lower electron-hole pairs' recombination rate,as well as wider and stronger visible light absorption capacity.Since the synergistic effect between g-C_(3 )N_(4) and MnFe_(2) O_(4),the photogene rated electron could transfer from g-C3 N4 to MnFe_(2) O_(4),which could promote the migration of electrons as well as enhance the photocatalytic activity and peroxymonosulfate(PMS) activation efficiency.Mn/G/D-5% composite displayed the excellent degradation performance of bisphenol A(BPA) with the removal efficiency of 99.9% under PMS/Vis system,which was approximately 2.47 and 63.8 times as high as that of the Mn/G/D-5%/PMS and Mn/G/D-5%/Vis system,respectively.Moreover,negative electricity derived from diatomite surface also promoted the photogenerated carriers' migration,and the degradation rate constant was around 2.4 times higher than that of MnFe_(2) O_(4)/g-C_(3) N_(4)(Mn/G).In addition,quenching experiments showed that both radical pathway(h^(+),·OH,·O_(2)^(-)and SO_(4)·^(-)) and non-radical pathway(^(1) O_(2)) were responsible for the degradation of BPA. | Xiangwei Zhang Chunquan Li Ting Chen Ye Tan Xiaorui Liu Fang Yuan Shuilin Zheng Zhiming Sun | 2021 | International Journal of Mining Science and Technology2021，31，6： | 2 |
| 18 | Overview of the Mars climate station for Tianwen-1 mission显示文摘The background and scientific objectives of the Mars Climate Station(MCS)for Tianwen-1 are introduced,accompanied by a comparative review of the status of related meteorological observation missions and of advanced sensing technologies.As one of the China Tianwen-1 Mission’s principal scientific payloads,the MCS contains four measurement sensors and one electronic processing unit that are specially designed to measure local temperature,pressure,wind,and sound on the Martian surface.The MCS’s measurement principles,technical schemes,ground calibration techniques,and adaptability evaluation to the Mars surface environment of MCS are introduced in details.The conclusion presents measurement performance specifications of the MCS,based on ground test results,that will provide guidance to future research based on data from the Tianwen-1 and later Mars missions. | YongQing Peng LeiBo Zhang ZhiGuo Cai ZhaoGang Wang HaiLong Jiao DongLi Wang XianTao Yang LianGuo Wang Xu Tan Feng Wang Jing Fang ZhouLu Sun HongLiang Feng XiaoRui Huang Yan Zhu Ming Chen LiangHai Li YanHua Li | 2020 | Earth and Planetary Physics2020，4，4： | 2 |
| 19 | Hydrothermal synthesis and visible-light photocatalytic activity of α-Fe 2 O 3 /TiO 2 composite hollow microspheres显示文摘 | Hua Tang Du Zhang Guogang Tang Xiaorui Ji Wenjing Li Changsheng Li Xiaofei Yang | 2013 | Ceramics International2013，，： | 2 |
| 20 | Effects of 5-Aminolevulinic Acid on the Content of Total Flavonoids and Expression of CHS and CHI Genes in Young Apples显示文摘[Objective] This study aimed to investigate the effects of 5-aminolevulinic acid( ALA) on the content of total flavonoids and relative expression levels of chalcone sythase( CHS) and chalcone isomerase( CHI) genes in young apples to determine the appropriate ALA concentration and processing time. [Method]Before thinning,young apples were treated with 0( CK),100,200,300 and 400 mg / L ALA. At 12 d after ALA treatment,the content of total flavonoids in young apples was determined by ultraviolet spectrophotometry. The relative expression levels of CHS and CHI genes in young apples were determined by q PCR. [Result]When ALA concentration was 0- 300 mg / L,the content of total flavonoids and relative expression levels of CHS and CHI genes in young apples were improved with the increase of ALA concentration. As ALA concentration rose to 400 mg / L,various indicators showed a downward trend. Moreover,the content of total flavonoids and relative expression levels of CHS and CHI genes in young apples treated with different concentrations of ALA were improved significantly,which reached the maximum at 9 d and declined since 12 d. [Conclusion] Compared with CK,spraying young apples with 300 mg / L ALA at 6- 9 d before thinning was conducive to improving the content of flavonoids in thinned young apples. | Lei CHEN Yurong GUO Xiaorui ZHANG Ruifang MI | 2015 | Agricultural Biotechnology2015，4，3： | 2 |
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