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| 1 | ZmCOL3, a CCT gene represses flowering in maize by interfering with the circadian clock and activating expression of ZmCCT显示文摘Flowering time is a trait vital to the adaptation of flowering plants to different environments.Here, we report that CCT domain genes play an important role in flowering in maize(Zea mays L.).Among the 53 CCT family genes we identified in maize, 28 were located in flowering time quantitative trait locus regions and 15 were significantly associated with flowering time, based on candidate-gene association mapping analysis.Furthermore, a CCT gene named ZmCOL3 was shown to be a repressor of flowering.Overexpressing ZmCOL3 delayed flowering time by approximately 4 d, in either long-day or short-day conditions.The absence of one cytosine in the ZmCOL3 3'UTR and the presence of a 551 bp fragment in the promoter region are likely the causal polymorphisms contributing to the maize adaptation from tropical to temperate regions.We propose a modified model of the maize photoperiod pathway, wherein ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock. | Minliang Jin Xiangguo Liu Wei Jia Haijun Liu Wenqiang Li Yong Peng Yanfang Du Yuebin Wang Yuejia Yin Xuehai Zhang Qing Liu Min Deng Nan Li Xiyan Cui Dongyun Hao Jianbing Yan | 2018 | Journal of Integrative Plant Biology2018，60，6： | 14 |
| 2 | Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Cervical Cancer—China,2003–2017显示文摘Introduction:This study reported the trends and analyzed the age-period-cohort effects on the incidence and mortality rates of cervical cancer in China.Methods:The age-standardized incidence rate(ASIR)and mortality rate(ASMR)by Segi’s world standard population were calculated using qualified consecutive data from 22 cancer registries from 2003 to 2017 in China.We performed joinpoint analysis to describe the trends and age-period-cohort analysis to estimate the independent effects of age,period and cohort on trends in incidence and mortality rates of cervical cancer.Results:The ASIR and ASMR for cervical cancer in females over 20 years old increased during 2003−2017.For females<50 years,a decreasing trend in ASIR and a stable trend in ASMR were observed in urban areas after 2009.But the ASIR and ASMR kept increasing in rural areas during the whole period.For females>50 years,the ASIR and ASMR increased both in urban and rural areas.Age-period-cohort analysis showed increasing period effects on cervical cancer incidence and mortality during the whole period.The cohort effects exhibited a downward-upwarddownward pattern for the incidence(1918–1938,1938–1963,1963–1993)and mortality rates(1918–1943,1943–1963,1963–1993)in urban areas,a fluctuating pattern for incidence rate and a continuing downward pattern for mortality rate(1918–1993)in rural areas.Conclusions:The increases in cervical cancer incidence and mortality rates can be mostly explained by period effects.We observed decreases in risk for cervical cancer incidence and mortality in young female generations,which were more obvious in urban areas. | Kexin Sun Rongshou Zheng Lin Lei Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen Bingfeng Han Ji Peng Wenqiang Wei Jie He | 2022 | China CDC weekly2022，4，48： | 4 |
| 3 | Experimental and numerical investigation on opposing plasma synthetic jet for drag reduction显示文摘Experimental and numerical studies are carried out to validate the potential of opposing Plasma Synthetic Jet(PSJ)for drag reduction for a hemisphere.Firstly,flow field changes of opposing PSJ are analyzed by comparing the experimental schlieren images and simulation results in a supersonic free stream of Mach number 3.As PSJ is a kind of unsteady pulsed jet,the shock standoff distance increases initially and then decreases under the control of PSJ,which corresponds to the change of the strength of PSJ.Accordingly,the amount of drag reduction of the hemisphere increases initially and then decreases.It is found that there is a short period of“drag rise”during the formation of PSJ before the drag reduction,which is induced by the generation of normal shock waves and the area difference of the cavity wall of PSJ Actuator(PSJA).Secondly,the effects of five parameters,including exit diameter,discharge energy of PSJA,Mach number,static pressure of incoming flow and angle of attack,on drag reduction of opposing PSJ were studied in detail by using numerical method.It is found that the Maximum Pressure Ratio(MPR)has a significant impact on the average drag reduction for a configuration-determined PSJA.For the configuration selected in this study,the flow field of opposing PSJ shows typical Short Penetration Mode(SPM)in a control cycle of PSJ when the MPR is less than 0.89.However,the flow field shows typical Long Penetration Mode(LPM)at some time when the MPR is bigger than 0.89.Relatively better drag reduction is achieved in this case. | Wei XIE Zhenbing LUO Yan ZHOU Wenqiang PENG Qiang LIU Dengpan WANG | 2022 | Chinese Journal of Aeronautics2022，35，8： | 4 |
| 4 | Novel lift enhancement method based on zero-mass-flux jets and its adaptive controlling laws design显示文摘For lessening the weight and volume of flow control system,enlarging the circulation control applying area of angle of attack(AOA),and achieving nice controlling characteristics,a novel lift enhancement method based on dual synthetic jet actuators(DSJAs)and synthetic jet actuator(SJA),and an adaptive proportional integral and differential(PID)algorithm based on radial basis function neural network are introduced.DSJAs are uniformly located along the chord to suppress the separation and trailing-edge SJA is applied to achieve the high circulation.Velocities of actuators are modulated to realize the real speed profile and on–off controlling laws of DSJAs are designed.Numerical simulations show that DSJAs and SJA could suppress the separation completely and move leading-edge stagnation point and trailing-edge separation point downstream even at AOA of 19°,hence achieve the highest lift and nose-down moment augmentation(ΔCl_(max)=0.92,ΔCm_(max)=0.02534),andΔL/D can reach 11.39 at AOA of 18°.Stalling is delayed to more than 19°.Linear lift area and pitch-break angle are both increased to 16°.ΔCl/C_(μ) can reach 76.7,indicating the greatest control efficiency.The results of adaptive PID control,whose controlling effects are proved better than PID,indicate that lift could track the objective with the rise time of 0.0325 s and finally keep steady,suggesting the nice stability and rapidness. | Zhijie Zhao Zhenbing Luo Bin Xu Xiong Deng Yuyan Guo Wenqiang Peng Shiqing Li | 2021 | Acta Mechanica Sinica2021，37，10： | 3 |
| 5 | Moving RNA moves RNA forward显示文摘Cell communication affects all aspects of cell structure and behavior,such as cell proliferation,differentiation,division,and coordination of various physiological functions.The moving RNA in plants and mammalian cells indicates that nucleic acid could be one of the various types of messengers for cell communication.The microvesicle is a critical pathway that mediates RNA moving and keeps moving RNA stable in body fluids.When moving miRNA enters the target cell,it functions by altering the gene expression profile and significantly inhibiting mRNA translation in recipient cells.Thus,moving RNA may act as a long-range modulator during development,organogenesis,and tumor metastasis. | PENG LiNa LI YuJiao ZHANG Lan YU WenQiang | 2013 | Science China(Life Sciences)2013，56，10： | 2 |
| 6 | Hymecromone:a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression显示文摘Currently,there is no effective drugs for treating clinically COVID-19 except dexamethasone.We previously revealed that human identical sequences of SARS-CoV-2 promote the COVID-19 progression by upregulating hyaluronic acid(HA).As the inhibitor of HA synthesis,hymecromone is an approved prescription drug used for treating biliary spasm.Here,we aimed to investigate the relation between HA and COVID-19,and evaluate the therapeutic effects of hymecromone on COVID-19.Firstly,HA was closely relevant to clinical parameters,including lymphocytes(n=158;r=−0.50;P<0.0001),C-reactive protein(n=156;r=0.55;P<0.0001),D-dimer(n=154;r=0.38;P<0.0001),and fibrinogen(n=152;r=0.37;P<0.0001),as well as the mass(n=78;r=0.43;P<0.0001)and volume(n=78;r=0.41;P=0.0002)of ground-glass opacity,the mass(n=78;r=0.48;P<0.0001)and volume(n=78;r=0.47;P<0.0001)of consolidation in patient with low level of hyaluronan(HA<48.43 ng/mL).Furthermore,hyaluronan could directly cause mouse pulmonary lesions.Besides,hymecromone remarkably reduced HA via downregulating HAS2/HAS3 expression.Moreover,89%patients with hymecromone treatment had pulmonary lesion absorption while only 42%patients in control group had pulmonary lesion absorption(P<0.0001).In addition,lymphocytes recovered more quickly in hymecromone-treated patients(n=8)than control group(n=5)(P<0.05).These findings suggest that hymecromone is a promising drug for COVID-19 and deserves our further efforts to determine its effect in a larger cohort. | Shuai Yang Yun Ling Fang Zhao Wei Li Zhigang Song Lu Wang Qiuting Li Mengxing Liu Ying Tong Lu Chen Daoping Ru Tongsheng Zhang Kaicheng Zhou Baolong Zhang Peng Xu Zhicong Yang Wenxuan Li Yuanlin Song Jianqing Xu Tongyu Zhu Fei Shan Wenqiang Yu Hongzhou Lu | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 2 |
| 7 | Rice SPL10 positively regulates trichome development through expression of HL6 and auxin-related genes显示文摘Trichomes function in plant defenses against biotic and abiotic stresses;examination of glabrous lines,which lack trichomes,has revealed key aspects of trichome development and function.Tests of allelism in 51 glabrous rice(Oryza sativa)accessions collected worldwide identified OsSPL10 and OsWOX3B as regulators of trichome development in rice.Here,we report that OsSPL10 acts as a transcriptional regulator controlling trichome development.Haplotype and transient expression analyses revealed that variation in the approximately 700-bp OsSPL10 promoter region is the primary cause of the glabrous phenotype in the indica cultivar WD-17993.Disruption of OsSPL10 by genome editing decreased leaf trichome density and length in the NIL-HL6 background.Plants with genotype OsSPL10^(WD-17993)/HL6 generated by crossing WD-17993 with NIL-HL6 also had fewer trichomes in the glumes.HAIRY LEAF6(HL6)encodes another transcription factor that regulates trichome initiation and elongation,and OsSPL10 directly binds to the HL6 promoter to regulate its expression.Moreover,the transcript levels of auxin-related genes,such as OsYUCCA5 and OsPIN-FORMED1b,were altered in OsSPL10 overexpression and RNAi transgenic lines.Feeding tests using locusts(Locusta migratoria)demonstrated that non-glandular trichomes affect feeding by this herbivore.Our findings provide a molecular framework for trichome development and an ecological perspective on trichome functions. | Jinjie Li Bo Tang Yingxiu Li Chenguang Li Minjie Guo Haiyang Chen Shichen Han Jin Li Qijin Lou Wenqiang Sun Peng Wang Haifeng Guo Wei Ye Zhanying Zhang Hongliang Zhang Sibin Yu Long Zhang Zichao Li | 2021 | Journal of Integrative Plant Biology2021，63，8： | 2 |
| 8 | 2,5-Diformylfuran production by photocatalytic selective oxidation of 5-hydroxymethylfurfural in water using MoS_(2)/CdIn_(2)S_(4) flower-like heterojunctions显示文摘The selective oxidation of 5-hydroxymethylfurfural(HMF) into 2,5-diformylfuran(DFF) is an important reaction for renewable biomass building blocks. Compared with thermal catalytic processes, photocatalytic production of DFF from HMF has attracted tremendous attention. Herein, the MoS_(2)/CdIn_(2)S_(4)(MC)flower-like heterojunctions were prepared and considered as photocatalysts for selective oxidation of HMF into DFF under visible-light irradiation in aqueous solution. Results demonstrated MoS_(2) in MC heterojunction could promote the separation of photoexcited electron-hole pairs, while the amount of MoS_(2) dropping was proved influenced on the photocatalytic performance. 80.93% of DFF selectivity was realized when using 12.5% MC as photocatalyst. In addition, the MC catalyst also showed great potential in transformation of other biomass derived benzyl-and furyl-alcohols. The catalytic mechanism suggested that ·O_(2)^(-) was the decisive active radical for HMF oxidation. Therefore, the MC heterojunction could be applied in photocatalytic conversion of biomass to valuable chemicals under ambient condition. | Qian Zhu Yan Zhuang Hongqing Zhao Peng Zhan Cong Ren Changsheng Su Wenqiang Ren Jiawen Zhang Di Cai Peiyong Qin | 2023 | Chinese Journal of Chemical Engineering2023，54，2： | 2 |
| 9 | Experimental investigation on ice-breaking performance of a novel plasma striker显示文摘Aircraft icing has long been a plague to aviation for its serious threat to flight safety.Recently,researches about a newly proposed deicing method based on Plasma Synthetic Jet Actuator(PSJA)have just started.To meet the requirements of in-flight deicing,structure of PSJA needs to be adjusted.This paper completed the detailed design and experimental validation of a novel plasma striker,which was a modified version of PSJA.Influences of mass of the moving part and rod shapes on the ice-breaking performances were also studied.Besides,a“conical-nosed rod configuration”was proposed.Its purpose was to ensure a good ice-breaking performance of the plasma striker on long ice,by generating a splitting failure.Results show that,though mass of the moving part was just several grams,ice-breaking performance was better when the mass was lighter.The rectangular rod could generate an elliptical circumferential crack,whose major axis was parallel to the direction of the long side of the rectangular rod.And the“conical-nosed rod”concept was verified to be able to generate a splitting crack which can spread completely to the far end of long ice,and the crack direction was parallel to edge line of the cone.In general,the plasma striker has the advantages of simple structure,low energy consumption,little harm to the flow field and the aircraft skin.Simulations will be carried out in future works to study in detail the working process of the plasma striker. | Tianxiang GAO Zhenbing LUO Yan ZHOU Shengke YANG Wenqiang PENG Xiong DENG Pan CHENG | 2022 | Chinese Journal of Aeronautics2022，35，1： | 2 |
| 10 | National Cancer Data Linkage Platform of China:Design,Methods,and Application显示文摘Background:The National Cancer Center(NCC)and China CDC cooperatively designed a National Cancer Data Linkage(NCDL)Platform to fulfill the task of sharing cancer outcome data through an automatic web-based system.Methods:NCC and China CDC established a web-based NCDL Platform to link death information from China CDC with the cancer database from NCC.Overall,76,708 cancer patients’data were analyzed to assess the feasibility and match rate of the NCDL Platform for 7 major cancers.Results:The function of the platform includes a data application and approval system,data linkage module,and results visualization system.Through the platform,38.9%cases were identified as deaths cases from the NCDL Platform in the first 3 years after cancer diagnosis.The linkage rate was highest in liver cancer and lowest in breast cancer.Conclusions:The NCDL Platform provides a powerful and efficient way to link national vital statistics with national cancer programs’data.Expanding cancer outcome data linkage may not only improve data collection efficiency,but also improve data use. | Hongmei Zeng Yunning Liu Lijun Wang Peng Yin Baohua Wang Ruiying Fu Xianhui Ran Rongshou Zheng Siwei Zhang Jiangmei Liu Jinling You Kexin Sun Shaoming Wang Li Li Ru Chen Wenqiang Wei Maigeng Zhou Jing Wu Jie He | 2022 | China CDC weekly2022，4，13： | 1 |
| 11 | Array-level boosting method with spatial extended allocation to improve the accuracy of memristor based computing-in-memory chips显示文摘Memristor based computing-in-memory chips have shown the potentials to accelerate deep neural networks with high energy efficiency. Due to the inherent filament-based conductive mechanism of the memristor, the reading and writing noises are hard to eliminate. Besides, the precision of the large-scale memristor array is still limited. However, when the noise of the memristor is large, the existing training methods to reduce the accuracy loss of memristor based computing-in-memory chips will face challenges.Hence, we proposed the array-level boosting method with spatial extended allocation to reduce the accuracy loss induced by the limited precision and large noises. To optimize the spatial allocation number of each layer in the neural network, the greedy spatial extended allocation algorithm is also proposed. The image processing and classification tasks are demonstrated based on fabricated 32×128 memristor arrays to valid the performance of the proposed method. The chip-in-loop results show that the recovered accuracy of ResNet-34 on CIFAR-10 with array-level boosting method is 92.3%, which is closed to software-based accuracy of 93.2%. | Wenqiang ZHANG Bin GAO Peng YAO Jianshi TANG He QIAN Huaqiang WU | 2021 | Science China(Information Sciences)2021，64，6： | 1 |
| 12 | Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Female Breast Cancer—China,2003-2017显示文摘Introduction:This study reported the trends in female breast cancer incidence and mortality rates in China,and analyzed the corresponding age-periodcohort effects.Methods:Data from 22 population-based cancer registries in China between 2003 and 2017 were analyzed.Age-standardized incidence rates(ASIR)and mortality rates(ASMR)were calculated using Segi’s world standard population.Joinpoint regression was employed to evaluate trends,and age-period-cohort effects were examined using the intrinsic estimator method.Results:The ASIR for female breast cancer exhibited a more rapid increase in rural areas compared to urban areas across all age groups.The most substantial increase was observed in the 20-34 age group in rural areas[annual percent change(APC)=9.0%,95%confidence interval(CI):7.0%-11.0%,P<0.001].The ASMR for females under 50 years old remained stable from 2003 to 2017 in both urban and rural areas.However,the ASMR for females over 50 in rural areas and those over 65 in urban areas demonstrated a significant increase,with the most pronounced increase observed among females over 65 in rural areas(APC=4.9%,95%CI:2.8%-7.0%,P<0.001).Age-period-cohort analysis revealed increasing period effects and decreasing cohort effects for female breast cancer incidence and mortality rates in both urban and rural settings.Notably,the cohort effect for incidence displayed a slight upward trend for females born between 1983 and 1992 in rural areas.Conclusions:Our study revealed a rapid increase in breast cancer incidence among younger generations and an accelerated mortality rate in older populations residing in rural areas.To effectively address the growing burden of female breast cancer in China,it is essential to develop and implement targeted intervention strategies. | Kexin Sun Lin Lei Rongshou Zheng Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen Bingfeng Han Ji Peng Wenqiang Wei Jie He | 2023 | China CDC weekly2023，5，15： | 1 |
| 13 | Experimental demonstration of nonlinear quantum metrology with optimal quantum state显示文摘Nonlinear quantum metrology may exhibit better precision scalings. For example, the uncertainty of an estimated phase may scale as ??∝1/(N^2) under quadratic phase accumulation, which is 1/N times smaller than the linear counterpart, where N is probe number. Here, we experimentally demonstrate the nonlinear quantum metrology by using a spin-I(I > 1/2) nuclear magnetic resonance(NMR) ensemble that can be mapped into a system of N=2I spin-1/2 particles and the quadratic interaction can be utilized for the quadratic phase accumulation. Our experimental results show that the phase uncertainty can scale as ??∝1/(N^2-1)by optimizing the input states, when N is an odd number. In addition, the interferometric measurement with quadratic interaction provides a new way for estimating the quadrupolar coupling strength in an NMR system. Our system may be further extended to exotic nonlinear quantum metrology with higher order many-body interactions. | Xinfang Nie Jiahao Huang Zhaokai Li Wenqiang Zheng Chaohong Lee Xinhua Peng Jiangfeng Du | 2018 | Science Bulletin2018，63，8： | 1 |
| 14 | Effects of Siraitia grosvenorii extracts on high fat diet-induced obese mice:a comparison with artificial sweetener aspartame显示文摘Long-term artificial sweetener intake is linked to increased risk of obesity. In the present study, supplement of natural sweetener from Siraitia grosvenorii(SG)(or Momordica grosvenorii) fruit, compared with the artificial sweetener aspartame(ASM), was evaluated for anti-obesity effects on mice fed with high fat diet(HFD). We found that, in contrary to ASM, SG extracts prevented body weight gain, the insulin resistance and fat mass accumulation in HFD mice. SG extracts treatment inhibited the infiltration of inflammatory macrophages and lowered the levels of the fat inflammatory cytokines(leptin, macrophage chemoattractant protein 1(MCP-1) and tumor necrosis factor-α(TNF-α)) in adipose tissues. In addition, SG extracts supplement counteracted the remodeling of gut microbiota resulted from HFD. However, ASM supplement aggravated the HFD-induced obese performances, fat inflammation and dysregulation of gut microbiota. Taken together, our results indicate that supplement of SG extracts may represent a promising alternation of artificial sweeteners in preventing metabolic diseases. | Ke Lü Xiaowan Song Peng Zhang Wei Zhao Ning Zhang Fan Yang Wenqiang Guan Jianfu Liu He Huang Chi-Tang Ho Rong Di Hui Zhao | 2022 | Food Science and Human Wellness2022，11，4： | 1 |
| 15 | Comparing independent climate-sensitive models of aboveground biomass and diame ter grow th with their compatible simultaneous model system for three larch species in China显示文摘Accurate estimate of tree biomass is essential for forest management.In recent years,several climate-sensitive allometric biomass models with diameter at breast height(D)as a predictor have been proposed for various tree species and climate zones to estimate tree aboveground biomass(AGB).But the allometric models only account for the potential effects of climate on tree biomass and do not simultaneously explain the influence of climate on D growth.In this study,based on the AGB data from 256 destructively sampled trees of three larch species randomly distributed across the five secondary climate zones in northeastern and northern China,we first developed a climate-sensitive AGB base model and a climate-sensitive D growth base model using a nonlinear least square regression separately.A compatible simultaneous model system was then developed with the climate-sensitive AGB and D growth models using a nonlinear seemingly unrelated regression.The potential effects of several temperature and precipitation variables on AGB and D growth were evaluated.The fitting results of climatic sensitive base models were compared against those of their compatible simultaneous model system.It was found that a decreased isothermality([mean of monthly(maximum temperatureminimum temperature)]/(Maximum temperature of the warmest month-Minimum temperature of the coldest month))and total growing season precipitation,and increased annual precipitation significantly increased the values of AGB;an increase of temperature seasonality(a standard deviation of the mean monthly temperature)and precipitation seasonality(a standard deviation of the mean monthly precipitation)could lead to the increase of D.The differences of the model fitting results between the compatible simultaneous system with the consideration of climate effects on both AGB and D growth and its corresponding climate-sensitive AGB and D growth base models were very small and insignificant(p>0.05).Compared to the base models,the inhere nt correlation of AGB with D was taken into account effectively by the proposed compatible model system developed with the climate-sensitive AGB and D grow th models.In addition,the compatible properties of the estimated AGB and D were also addressed substantially in the proposed model system. | Zhigang Gao Qiuyan Wang Zongda Hus Peng Luo Guangshuang Duan Ram PSharma Qiaolin Ye Wenqiang Gao Xinyu Song Liyong Fut | 2019 | International Journal of Biomathematics2019，12，7： | 1 |
| 16 | Erratum to: Algorithmic cooling based on cross-relaxation and decoherence-free subspace [Sci. China-Phys. Mech. Astron. 63, 270311 (2020)]显示文摘In this work,HengYan Wang and Jian Pan contributed equally to this work.The annotation for the contribution was omitted in the original publication of this paper[I].It can be conformed in the submitted PDF version of the manuscript.Hence,the sentence“HengYan Wang and Jian Pan conjtributed equally to this work.”should be added. | HengYan Wang Jian Pan WenQiang Zheng and XinHua Peng | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，8： | 1 |
| 17 | Ultrasmooth surface polishing based on the hydredynamie effect显示文摘 | Wenqiang Peng Chaoliang Guan and Shengyi Li | 2013 | Applied Optics2013，52，25： | 1 |
| 18 | Decorating MXene with tiny ZIF-8 nanoparticles:An effective approach to construct composites for water pollutant removal显示文摘MXenes have attracted increasing research enthusiasm owing to their unique physical and chemical properties.Although MXenes exhibit exciting potential in cations adsorption due to their unique surface groups,the adsorption capacity is limited by the low specific surface area and undeveloped porosity.Our work aims at enhancing the adsorption performance of a well-known MXene,Ti3C2Tx,for methylene blue(MB)by decorating tiny ZIF-8 nanoparticles in the interlayer.After the incorporation of ZIF-8,suitable interspace in the layers resulting from the distribution of tiny ZIF-8 appears.When employing in MB,the adsorption capacity of composites can reach up to 107 mg·g^(-1) while both ZIF-8(3 mg·g^(-1))and Ti_(3)C_(2)Tx(9mg·g^(-1))show nearly no adsorption capacity.The adsorption mechanism was explored,and the good adsorption capacity is caused by the synergistic effect of ZIF-8 and Ti_(3)C_(2)Tx,for neither of them is of suitable interspace or surface groups for MB adsorption.Our work might pave the way for constructing functional materials based on the introduction of nanoparticles into layered materials for various adsorption applications. | Chen Gu Wenqiang Weng Cong Lu Peng Tan Yao Jiang Qiang Zhang Xiaoqin Liu Linbing Sun | 2022 | Chinese Journal of Chemical Engineering2022，35，2： | 1 |
| 19 | Mutually exclusive epigenetic modification on SIX6 with hypermethylation for precancerous stage and metastasis emergence tracing显示文摘Dear Editor,Aberrant DNA methylation gets involved in cancer initiation,progression,and recurrence,which in turn makes it an ideal cancer biomarker.Various methylation markers or their panels have been developed in diverse cancer types.However,the model-constructing based marker mining strategy and incompatibility of application have greatly impeded their ways to clinic.Thus,single methylation marker applicable to all/most cancer types and multiple clinical scenarios is desperately needed.The hope came from the unexpected observation that HIST1H4F was universally hypermethylated in all 17 cancer types;thus,we raised the concept of“Universal Cancer Only Marker(UCOM)”and established a paradigm for discovery and clinical application of UCOM.1 Recently,a novel UCOM,hypermethylated PCDHGB7,was identified and found to advance cervical cancer(CC)screening to the precancerous stage.2 During the screening of UCOM,we discerned a bunch of cancer cell-differentially methylated regions.1 Among them,sine oculis(SIX)homeobox family of transcription factors,which were found to function as tumorigenesis regulator by promoting epithelial-to-mesenchymal transition and metastasis recently in addition to their traditional roles in tissue formation and organogenesis,3 sparked our special attention.Herein,we interrogate whether SIX6 methylation could serve as a novel UCOM and its potential applications. | Shihua Dong Zhicong Yang Peng Xu Wanxiang Zheng Baolong Zhang Fangqiu Fu Zhanrui Mao Jianlin Yuan Haiquan Chen Wenqiang Yu | 2022 | Signal Transduction and Targeted Therapy2022，7，8： | 1 |
| 20 | 4350<ce:hsp sp='0.25'/>W quasi-continuous-wave operation of a diode face-pumped ceramic Nd: YAG slab laser显示文摘 | Junchi Chen Jiang Li Jialin Xu Wenbin Liu Yong Bo Xiqi Feng Yiting Xu Dongliang Jiang Zhongzheng Chen Yubai Pan Yading Guo Biao Yan Chang Guo Lei Yuan Hongtao Yuan Yanyong Lin Yunsheng Xiao Qinjun Peng Wenqiang Lei Dafu Cui Zuyan Xu | 2014 | Optics and Laser Technology2014，，： | 1 |
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