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| 1 | Life prognosis of sentinel node navigation surgery for early-stage gastric cancer:Outcome of lymphatic basin dissection显示文摘BACKGROUND Lymphatic basin dissection is a sentinel node biopsy method that is specific for gastric cancer.In this method,the dyed lymphatic system is dissected en bloc,and sentinel nodes are identified at the back table(ex vivo).Even with lymphatic basin dissection,blood flow to the residual stomach can be preserved,and functionpreserving curative gastrectomy can be performed.The oncological safety of function-preserving curative gastrectomy combined with lymphatic basin dissection has not yet been fully investigated.We hypothesized that the oncological safety of sentinel node navigation surgery(SNNS)is not inferior to that of the guidelines.AIM To investigate the life prognosis of SNNS for gastric cancer in comparison with guidelines surgery.METHODS This was a retrospective cohort study.Patients were selected from gastric cancer patients who underwent sentinel node biopsy from April 1999 to March 2016.Patients from April 1999 to August 2008 were from the Department of Surgery II,Kanazawa University Hospital,and patients from August 2009 to March 2016 were from the Department of Surgical Oncology,Kanazawa Medical University Hospital.Patients who were diagnosed with gastric cancer,which was preoperatively diagnosed as superficial type(type 0),5 cm or less in length,clinical T1-2 and node negative,and underwent various gastrectomies guided by sentinel node navigation were retrospectively collected.The overall survival(OS)and relapsefree survival(RFS)of these patients(SNNS group)were investigated.Patients with gastric cancer of the same stage and who underwent guidelines gastrectomy with standard nodal dissection were also selected as the control group.RESULTS A total of 239 patients in the SNNS group and 423 patients in the control group were included.Pathological nodal metastasis was observed in 10.5%and 10.4%of the SNNS and control groups,respectively.The diagnostic abilities of sentinel node biopsy were 84%and 98.6%for sensitivity and accuracy,respectively.In the SNNS group,81.6%of patients underwent modified gastrectomy or functionpreserving curative gastrectomy with lymphatic basin dissection,in which the extent of nodal dissection was further reduced compared to the guidelines.The OS rate in the SNNS group was 96.8%at 5 years and was significantly better than 91.3%in the control group(P=0.0014).The RFS rates were equal in both groups.After propensity score matching,there were 231 patients in both groups,and the cumulative recurrence rate was 0.43%at 5 years in the SNNS group and 1.30%in the control group,which was not statistically different.CONCLUSION The oncological safety of patients who undergo gastrectomy guided by sentinel node navigation is not inferior to that of the guidelines surgery. | Shinichi Kinami Naohiko Nakamura Tomoharu Miyashita Hidekazu Kitakata Sachio Fushida Takashi Fujimura Yasuo Iida Noriyuki Inaki Toru Ito Hiroyuki Takamura | 2021 | World Journal of Gastroenterology2021，27，46： | 5 |
| 2 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 2 |
| 3 | Role of MMP-7 in the formation of peritoneal dissemination in gastric cancer显示文摘 | Yutaka Yonemura Yoshio Endou Hideto Fujita Sachio Fushida Etsurou Bandou Keizou Taniguchi Kouichi Miwa Kazuo Sugiyama Takuma Sasaki | 2000 | Gastric Cancer2000，，2： | 2 |
| 4 | PTD classification: proposal for a new classification of gastric cancer location based on physiological lymphatic flow显示文摘 | Shinichi Kinami Takashi Fujimura Eisuke Ojima Sachio Fushida Toshihiko Ojima Hiroshi Funaki Hideto Fujita Hiroyuki Takamura Itasu Ninomiya Genichi Nishimura Masato Kayahara Tetsuo Ohta Zen Yoh | 2008 | International Journal of Clinical Oncology2008，，4： | 2 |
| 5 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 6 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 1 |
| 7 | The role of human peritoneal mesothelial cells in the fibrosis and progressionof gastric cancer显示文摘 | Tomoya Tsukada Sachio Fushida Shinichi Harada Yasumichi Yagi Jun Kinoshita Katsunobu Oyama Hidehiro Tajima Hideto Fujita Itasu Ninomiya Takashi Fujimura Tetsuo Ohta | 2012 | International Journal of Oncology2012，，2： | 1 |
| 8 | The management of a remnant pancreatic stump for preventing the development of postoperative pancreatic fistulas after distal pancreatectomy: current evidence and our strategy显示文摘 | Isamu Makino Hirohisa Kitagawa Hisatoshi Nakagawara Hidehiro Tajima Itasu Ninomiya Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2013 | Surgery Today2013，，6： | 1 |
| 9 | Intraperitoneal hyperthermic treatment for peritoneal dissemination of colorectal cancers显示文摘 | Dr. Akio Yamaguchi M. D. Yuuji Tsukioka M. D. Sachio Fushida M. D. Yoshiyuki Kurosaka M. D. Masahiro Kanno M. D. Yutaka Yonemura M. D. Kouichi Miwa M.D. Itsuo Miyazaki M. D | 1992 | Diseases of the Colon & Rectum1992，，10： | 1 |
| 10 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 11 | Transectional gastrectomy: An old but renewed concept for early gastric cancer显示文摘 | Takashi Fujimura Sachio Fushida Masato Kayahara Tetsuo Ohta Shinichi Kinami Koichi Miwa | 2010 | Surgery Today2010，，5： | 1 |
| 12 | Outcome of ratio of lymph node metastasis in gastric carcinoma显示文摘 | Etsuro Bando MD Yutaka Yonemura MD Keizo Taniguchi MD Sachio Fushida MD Takashi Fujimura MD Koichi Miwa MD | 2002 | Annals of Surgical Oncology2002，，8： | 1 |
| 13 | Outcome of ratio of lymph node metastasis in gastric carcinoma显示文摘 | Etsuro Bando MD Yutaka Yonemura MD Keizo Taniguchi MD Sachio Fushida MD Takashi Fujimura MD Koichi Miwa MD | 2002 | Annals of Surgical Oncology2002，，8： | 1 |
| 14 | Serum cytokeratin 18 as a biomarker for gastric cancer显示文摘 | Katsunobu Oyama Sachio Fushida Jun Kinoshita | 2013 | Clinical and Experimental Medicine2013，13，4： | 1 |
| 15 | Biodistribution of humanized anti-VEGF monoclonal antibody/bevacizumab on peritoneal metastatic models with subcutaneous xenograft of gastric cancer in mice显示文摘 | Yasumichi Yagi Sachio Fushida Shinichi Harada Tomoya Tsukada Jun Kinoshita Katsunobu Oyama Hideto Fujita Itasu Ninomiya Takashi Fujimura Masato Kayahara Seigo Kinuya Masakazu Yashiro Kousei Hirakawa Tetsuo Ohta | 2010 | Cancer Chemotherapy and Pharmacology2010，，4： | 1 |
| 16 | Sivelestat Sodium Hydrate Inhibits Neutrophil Migration to the Vessel Wall and Suppresses Hepatic Ischemia–Reperfusion Injury显示文摘 | Seisho Sakai Hidehiro Tajima Tomoharu Miyashita Shin-ichi Nakanuma Isamu Makino Hironori Hayashi Hisatoshi Nakagawara Hirohisa Kitagawa Sachio Fushida Takashi Fujimura Hidehito Saito Seiichi Munesue Yasuhiko Yamamoto Tetsuo Ohta | 2014 | Digestive Diseases and Sciences2014，，4： | 1 |
| 17 | Neoadjuvant chemotherapy for high-grade advanced gastric cancer显示文摘 | Yutaka Yonemura M.D. Tosiharu Sawa M.D. Kazuo Kinoshita M.D. Nobuo Matsuki M.D. Sachio Fushida M.D. Sigehiro Tanaka M.D. Shigekazu Ohoyama M.D. Tooru Takashima M.D. Hironobu Kimura M.D. Tooru Kamata M.D. Takashi Fujimura M.D. Kazuo Sugiyama M.D. Kouzou Sh | 1993 | World Journal of Surgery1993，，2： | 1 |
| 18 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 19 | Pioglitazone inhibits the proliferation and metastasis of human pancreaticcancer cells显示文摘 | Itasu Ninomiya Keisuke Yamazaki Katsunobu Oyama Hironori Hayashi Hidehiro Tajima Hirohisa Kitagawa Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2014 | Oncology Letters2014，，6： | 1 |
| 20 | Effects of intraoperative chemohyperthermia in patients with gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura Takashi Fujimura Genichi Nishimura Raul Falla Toshiharu Sawa Kanji Katayama Kouichirou Tsugawa Sachio Fushida Itsuo Miyazaki Motohiro Tanaka Yoshio Endou Takuma Sasaki | 1996 | Surgery1996，，4： | 1 |
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