|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of the management of high-risk population显示文摘Aim Cerebrovascular disease is the leading cause of death and disability in China,causing a huge burden among patients and their families.Hence,stroke prevention is critical,especially in the high-risk population.Here,we present the evidence-based guideline suitable for the Chinese population.Methods Literature search of PubMed and Cochrane library(from January 1964 to June 2019)was done.After thorough discussion among the writing group members,recommendations were listed and summarised.This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association’s Stroke.Results This evidence-based guideline was written in three parts:controlling the risk factors of stroke,utilisation of antiplatelet agents and assessing the risks of first-ever stroke.All recommendations were listed along with the recommending classes and levels of evidence.Conclusions This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China.Controlling related risk factors,appropriately using antiplatelet agents,assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China. | Yilong Wang Shangrong Han Haiqiang Qin Huaguang Zheng Bin Jiang Yong Cao Yuan Gao Ling Guan Qian Jia Yong Jiang Yuming Jiao Shuya Li Yapeng Li Zixiao Li Wei Liu Xiaojuan Ru Dongling Sun Haixin Sun Penglian Wang Tingting Wang Lixia Zong Lei Guo Xuewei Xie Yuming Xu Yuyuan Xu Xiaomeng Yang Yingying Yang Mengyuan Zhou Wenzhi Wang Chinese Stroke Association Stroke Council Guideline Writing Committee | 2020 | Stroke & Vascular Neurology2020，5，3： | 11 |
| 2 | Relationship between the temporal-spatial distribution of archaeological sites and natural environment from the Paleolithic Age to the Tang and Song Dynasties in the Three Gorges Reservoir of Chongqing area显示文摘The temporal-spatial distribution features including time distribution,horizontal and vertical spatial distribution of archaeological sites from the Paleolithic Age to the Tang and Song Dynasties in the Three Gorges Reservoir of Chongqing area are analyzed based on GIS spatial analysis.The successive pollen record of deposited peat stratum since the Paleolithic Age in the Dajiuhu Basin of Shennongjia is used in combination with the research of the historical environmental evolution to reconstruct the Paleoenvironment in the Three Gorges Reservoir of Chongqing area.Through the comparison of the temporal-spatial distribution of the archaeological sites and the natural environment,the relation between the distribution of the archaeological sites and the natural environment evolution and disaster changes from the Neolithic Age to the Tang and Song Dynasties has been discussed.Study shows that 677 archaeological sites from the Paleolithic Age to the Tang and Song Dynasties in the Three Gorges Reservoir of Chongqing area increase gradually from west to east and from high land to low land.Most of the sites are distributed along the river and aggregated at the confluence.Obviously,the altitudes of archaeological sites in the Paleolithic Age and the Neolithic Age are much higher than those of historical sites.The analysis suggests:(1)the human beings of every times would like to choose the first or the second river terrace as living sites which are nearer to the water source and are easier to with- stand flood.The pre-historical sites of earlier ages are often located at the higher altitude place because of the tectonic uplift and downcutting of rivers since Holocene.(2)Due to the rugged terrain in Chongqing area,most of the sites are located along the river sides,for example,the wide river valley and terrace,which could provide wider living space caused by the lateral erosion and deposition of the river course.(3)The early residents mainly relied on fishing,hunting and agriculture,and the rugged terrain of the mountainous area restricted the development of farming.However,in the confluence region,the fertilized plain provided an ideal location for farming and fishing.(4)The temporal-spatial distribution of archeological sites in this area is significantly affected by the climate condition. | ChaoGui Zheng Cheng Zhu YiShun Zhong PengLian Yin JiuJiang Bai ZhiBin Sun | 2008 | Chinese Science Bulletin2008，53，S1： | 11 |
| 3 | Gastrointestinal bleeding during acute ischaemic stroke hospitalisation increases the risk of stroke recurrence显示文摘Objective Gastrointestinal(GI)bleeding in patients who had a stroke is strongly associated with a higher risk of death and loss of independence.However,it is unknown whether GI bleeding increases risk for recurrence of stroke.In this study,we assess the potential relationship between GI bleeding and stroke recurrence in patients within 12 months of an acute ischaemic stroke(AIS),using the China National Stroke Registry(CNSR).Methods This study included 22216 patients who had an ischaemic stroke included in the CNSR from 2007 to 2008.We analysed baseline patient characteristics,GI bleeding and outcomes of patients who had an AIS,specifically stroke recurrence at 3,6 and 12 months.We used multivariable logistic regression to evaluate a possible association between GI bleeding and stroke recurrence.results Of the 12415 patients included in our study,12.3%,15.5%and 17.7%had a stroke recurrence at 3,6 and 12 months,respectively.GI bleeding was an independent stroke recurrence risk factor in patients after ischaemic stroke at 3 months(adjusted OR 1.481,95%CI 1.118 to 1.962),6 months(adjusted OR 1.448,95%CI 1.106 to 1.896)and 12 months(adjusted OR 1.350;95%CI 1.034 to 1.763).Conclusion GI bleeding was associated with the increased risk of stroke recurrence after an AIS. | Wanliang Du Xingquan Zhao Yilong Wang Yuesong Pan Gaifen Liu Anxin Wang Ruijun Ji Liping Liu Hongqiu Gu Kehui Dong Penglian Wang Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 7 |
| 4 | The efficacy and safety of nimodipine in acute ischemic stroke patients with mild cognitive impairment: a double-blind, randomized,placebo-controlled trial显示文摘Nimodipine might be effective in subcortical vascular dementia(VaD). Its benefit in preventing further cognitive decline in patients with acute ischemic stroke(AIS) and vascular mild cognitive impairment(VaMCI) remains to be established. In this multicenter, double-blind trial, we randomly assigned 654 eligible patients to nimodipine 30 mg three times a day or placebo. The primary outcome was any cognitive decline defined by the changes on the Mini-Mental State Examination(DMMSE à3) or vascular AD assessment scale cognitive subscale(DADAS-cog ! 4) at 6 months. Secondary outcomes included any distribution shift of DADAS-cog, DMMSE or cognitive improvement defined by DADAS-cog à2, or DMMSE ! 0. The primary outcome in the nimodipine group and placebo group were similar for DMMSE à3(4.18% and 7.22%, respectively, P = 0.15) and DADAS-cog ! 4(8.36% and 8.93% respectively,P = 0.88). The distribution shift of DADAS-cog and DMMSE differed significantly between the two groups(P = 0.03 and P = 0.05 respectively). Cognitive improvement occurred in 55.4% in the nimodipine group and 43.6% in the placebo group measured by DADAS-cog à2(Odds Ratio, 1.54; 95% confidence interval[CI] 1.10–2.14, P < 0.01) or 84.0% and 74.6% respectively by DMMSE ! 0(Odds Ratio, 1.79; 95% CI 1.18–2.70, P < 0.01). Nimodipine was associated with better cognitive function in the memory domain. The adverse events rate was similar in two groups. This study is registered with ClinicalTrials.gov,NCT01220622. Nimodipine did not show benefit to prevent cognitive decline in AIS patients with VaMCI, but improved cognition moderately, especially measured in the memory domain. | Huaguang Zheng Yilong Wang Anxin Wang Hao Li David Wang Xingquan Zhao Penglian Wang Haipeng Shen Lijun Zuo Yuesong Pan Zixiao Li Xia Meng Xianwei Wang Weixiong Shi Yi Ju Liping Liu Kehui Dong Chunxue Wang Rubo Sui Rong Xue Xiaoping Pan Xiaoyua Niu Benyan Luo Yi Sui Huali Wang Tao Feng Yongjun Wang | 2019 | Science Bulletin2019，64，2： | 5 |
| 5 | China Antihypertensive Trial in Acute Ischemic Stroke II (CATIS-2): rationale and design显示文摘Backgrounds Increased blood pressure(BP)for patients who had an acute ischaemic stroke is associated with poor functional outcome,however the optimal timing of antihypertensive therapy is unknown.Aims We aim to compare early antihypertensive treatment to delayed antihypertensive treatment for reducing the risk of composite major disability and mortality at 3 months in acute ischaemic stroke.Design The China Antihypertensive Trial in Acute Ischemic Stroke II(CATIS-2)trial is a multicentre,randomised,open-label,blinded-endpoints trial that will be conducted in 100 hospitals in China.The primary outcome is the composite of death and major disability(modified Rankin Scale score≥3)at 3 months of randomisation.Antihypertensive treatment will be received immediately after randomisation in the early treatment group,aimed at average systolic BP by 10%-20%reduction within the first 24 hours,and achieving an average BP level of<140/90 mm Hg within 5 days.Patients in the delayed treatment group will discontinue any antihypertension medications for the first 7 days of randomisation,and will receive antihypertensive therapy achieving a BP goal of<140/90 mm Hg after 7 days.Conclusion The CATIS-2 trial will be testing the hypotheses that early BP lowering leads to improved functional outcome without any other harms,and developing clinical guidelines of the BP management for patients who had an acute ischaemic stroke. | Liping Liu Yilong Wang Xuewei Xie Dacheng Liu Aili Wang Penglian Wang Suwen Shen Chongke Zhong Yufei Wei Tan Xu Yuesong Pan Yong Jiang Xia Meng David Wang Yonghong Zhang Jiang He Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 3 |
| 6 | Interrelationship Among Common Medical Complications After Acute Stroke: Pneumonia Plays an Important Role显示文摘 | Ruijun Ji David Wang Haipeng Shen Yuesong Pan Gaifen Liu Penglian Wang Yilong Wang Hao Li Yongjun Wang | 2013 | Stroke2013，，12： | 1 |
| 7 | Rationale and design of a double-blind,placebo-controlled,randomized trial to evaluate the safety a nd efficacy of nimodipine in preventing cognitive impairment in ischemic cerebrovascular e vents(NICE)显示文摘 | Penglian Wang Yongjun Wang Tao Feng | 2012 | BMC Neurology2012，12，： | 1 |
| 8 | Rationale and design of a double- blind,placebo-controlled,randomized trial to evaluate the safety and efficacy of ni- modipine in preventing cognitive impairment in ischemie eerebmvascular events显示文摘 | Penglian Wang Yongjun Wang Tao Feng | 2012 | (NICE) BMC Neuroh2012，，12： | 1 |
| 9 | Differential Proteomics Analysis on Fluoride-resistant Streptococcus mutans by Label-free Quantitation显示文摘 | ZHAO Hongyan ZHANG Zhimin ZHU Laikuan LI Zhenling LI Penglian LIU Jiabai ZHANG Zhiying | 2014 | Chemical Research in Chinese Universities2014，30，4： | 0 |
| 10 | In- hospital complications affect short- term and long- term mortality in ICH: a prospective cohort study显示文摘Background Medical complications strongly affected the mortality of patients with stroke.However,only limited research has studied the effect of in-hospital medical complications on the mortality of patients with spontaneous intracerebral haemorrhage(ICH)globally.Using the China National Stroke Registry,the effect was prospectively and systematically investigated in patients with spontaneous ICH during their hospitalisation,at 3,6 and 12 months after disease onset.Methods This study collected data on patients over 18 years old with spontaneous ICH from 132 Chinese clinical centres across 32 provinces and four municipalities(Hong Kong included),from September 2007 to August 2008.Data on patient complications,death and other information were acquired through paper-based registry forms.Using multivariable logistic regression,the association of medical complications with stroke outcomes was evaluated.Results Of 3255 patients with spontaneous ICH,878(26.97%)had in-hospital medical complications.In-hospital medical complications were independent risk factors for death during the hospitalisation(adjusted OR 4.41,95% CI 3.18 to 6.12),at 3 months(adjusted OR 2.18,95% CI 1.70 to 2.80),6 months(adjusted OR 1.84,95% CI 1.45 to 2.34)and 12 months(adjusted OR 1.59,95% CI 1.26 to 2.01)after spontaneous ICH.Conclusion The results revealed that the short-term and long-term mortality of patients with spontaneous ICH in China was significantly associated with their in-hospital medical complications. | Yaqing Zhang Yongjun Wang Ruijun Ji Anxin Wang Yilong Wang Zhonghua Yang Liping Liu Penglian Wang Xingquan Zhao | 2021 | Stroke & Vascular Neurology2021，6，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员