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| 1 | pORF5 plasmid protein of Chlamydia trachomatis induces MAPK-mediated pro-inflammatory cytokines via TLR2 activation in THP-1 cells显示文摘Infection with Chlamydia trachomatis induces inflammatory pathologies in the urogenital tract that can lead to infertility and ectopic pregnancy.Pathogenesis of infection has been mostly attributed to excessive cytokine production.However,precise mechanisms on how C.trachomatis triggers this production,and which protein(s) stimulate inflammatory cytokines remains unknown.In the present study,the C.trachomatis pORF5 protein induced tumor necrosis factor alpha(TNF-α),interleukin-1 beta(IL-1β) and interleukin-8(IL-8) in dose-and time-dependent manners in the THP-1 human monocyte cell line.We found that intracellular p38/mitogen-activated protein kinase(MAPK) and extracellular signal-regulated kinase(ERK)/MAPK signaling pathways were required for the induction of TNF-α,IL-1β and IL-8.Blockade of toll-like receptor 2(TLR2) signaling reduced induction levels of TNF-α,IL-8 and IL-1β.We concluded that the C.trachomatis pORF5 protein might contribute to the inflammatory processes associated with chlamydial infections. | ZHOU Hui HUANG QiuLin LI ZhongYu WU YiMou XIE XiaoBing MA KangKang CAO WenJuan ZHOU Zhou LU ChunXue ZHONG GuangMing | 2013 | Science China(Life Sciences)2013，56，5： | 26 |
| 2 | CRISPR/Cas9-mediated disruption of TaNP1 genes results in complete male sterility in bread wheat显示文摘Male sterile genes and mutants are valuable resources in hybrid seed production for monoclinous crops.High genetic redundancy due to allohexaploidy makes it difficult to obtain the nuclear recessive male sterile mutants through spontaneous mutation or chemical or physical mutagenesis methods in wheat.The emerging effective genome editing tool,CRISPR/Cas9 system,makes it possible to achieve simultaneous mutagenesis in multiple homoeoalleles.To improve the genome modification efficiency of the CRISPR/Cas9 system in wheat,we compared four different RNA polymerase(Pol)Ⅲpromoters(TaU3 p,TaU6 p,OsU3 p,and OsU6 p)and three types of sgRNA scaffold in the protoplast system.We show that the TaU3 promoter-driven optimized sgRNA scaffold was most effective.The optimized CRISPR/Cas9 system was used to edit three TaNP1 homoeoalleles,whose orthologs,OsNP1 in rice and ZmIPE1 in maize,encode a putative glucose-methanol-choline oxidoreductase and are required for male sterility.Triple homozygous mutations in TaNP1 genes result in complete male sterility.We further demonstrated that anyone wild-type copy of the three TaNP1 genes is sufficient for maintenance of male fertility.Taken together,this study provides an optimized CRISPR/Cas9 vector for wheat genome editing and a complete male sterile mutant for development of a commercially viable hybrid wheat seed production system. | Jian Li Zheng Wang Guangming He Ligeng Ma Xing Wang Deng | 2020 | Journal of Genetics and Genomics2020，47，5： | 12 |
| 3 | Bio-inspired Flow Sensing and Prediction for Fish-like Undulating Locomotion: A CFD-aided Approach显示文摘 | Han Zhou Tianjiang Hu Kin Huat Low Lincheng Shen Zhaowei Ma Guangming Wang Haijun Xu | 2015 | Journal of Bionic Engineering2015，12，3： | 7 |
| 4 | Optical Micro/Nano Fibers Enabled Smart Textiles for Human-Machine Interface显示文摘Wearable human-machine interface(HMI)is an advanced technology that has a wide range of applications from robotics to augmented/virtual reality(AR/VR).In this study,an optically driven wearable human-interactive smart textile is proposed by integrating a polydimethylsiloxane(PDMS)patch embedded with optical micro/nanofibers(MNF)array with a piece of textiles.Enabled by the highly sensitive pressure dependent bending loss of MNF,the smart textile shows high sensitivity(65.5 kPa^(−1))and fast response(25 ms)for touch sensing.Benefiting from the warp and weft structure of the textile,the optical smart textile can feel slight finger slip along the MNF.Furthermore,machine learning is utilized to classify the touch manners,achieving a recognition accuracy as high as 98.1%.As a proof-of-concept,a remote-control robotic hand and a smart interactive doll are demonstrated based on the optical smart textile.This optical smart textile represents an ideal HMI for AR/VR and robotics applications. | Shuqi Ma Xiaoyu Wang Pan Li Ni Yao Jianliang Xiao Haitao Liu Zhang Zhang Longteng Yu Guangming Tao Xiong Li Limin Tong Lei Zhang | 2022 | Advanced Fiber Materials2022，4，5： | 5 |
| 5 | Evaluation of external quality factor of the superconducting cavity using extrapolation method显示文摘The estimation of the external quality factor is important for designing coupling devices for the cavities.A new representation of the external quality factor calculations for single-cell cavity coupled to a coaxial transmission line is derived based on analytic analysis and numeric analysis with the help of 3D electromagnetic code,and verified with experimental measurements at room temperature.In logarithmic scale the results for the external quality factor were quasi-linear over the limited range,and the simulated and measured data could be used and extrapolated to the superconducting case.For the unpolished 1.5 GHz 3rd harmonic superconducting cavity,the discrepancy between the evaluation value and measurement result is less than 25% within an acceptable deviation. | MA Zhenyu MA Guangming HOU Hongtao YU Haibo ZHANG Rui LIU Jianfei | 2009 | Nuclear Science and Techniques2009，20，2： | 2 |
| 6 | In-Fiber Structured Particles and Filament Arrays from the Perspective of Fluid Instabilities显示文摘In-fiber structured particles and filament array have been recently emerging,providing unique advantages of feasible fabrication,diverse structures and sophisticated functionalities.This review will focus on the progress of this topic mainly from the perspective of fluid instabilities.By suppressing the capillary instability,the uniform layered structures down to nanometers are attained with the suitable materials selection.On the other hand,by utilizing capillary instability via post-drawing thermal treatment,the unprecedent structured particles can be designed with multimaterials for multifunctional fiber devices.Moreover,an interesting filamentation instability of a stretching viscous sheet has been identified during thermal drawing,resulting in an array of filaments.This review may inspire more future work to produce versatile devices for fiber electronics,either at a single fiber level or in large-scale fabrics and textiles,simply by manipulating and controlling fluid instabilities. | Bingrui Xu Shuqi Ma Yuanzhuo Xiang Jing Zhang Meifang Zhu Lei Wei Guangming Tao Daosheng Deng | 2020 | Advanced Fiber Materials2020，2，1： | 2 |
| 7 | Molecular analysis of cell-free DNA identifies distinct molecular features in patients with chemosensitive and chemorefractory small cell lung cancer显示文摘Dear Editor,Lung cancer is the predominant cause of cancer-related death worldwide[1].Non-small cell lung cancer accounts for 80%-85%and small cell lung cancer(SCLC)accounts for 15%-20%of all lung cancer cases[2].Patients with SCLC,a highly aggressive and poorly differentiated malignancy,have an alarming average 5-year overall sur-vival rate of less than 10%[3].Most patients with SCLC already show clinically detectable metastases at diag-nosis and have extremely poor prognoses,even when treated with multimodality therapy[4].Before the addi-tion of atezolizumab to chemotherapy became the first-line treatment of extensive-stage SCLC,chemotherapy is the primary treatment of SCLC[5]. | Jie Zhang Chen Tian Fang Lv Jianfei Wang Wenbo Han Jun Nie Ling Dai Weiheng Hu Xiaoling Chen Xiangjuan Ma Guangming Tian Di Wu Sen Han Yang Wang Jieran Long Ziran Zhang Jian Fang Henghui Zhang | 2019 | Cancer Communications2019，39，1： | 2 |
| 8 | WEEE recovery strategies and the WEEE treatment status in China显示文摘 | WENZHI HE GUANGMING LI XINGFA MA ETC | 2006 | Journal of Hazardous Materials2006，136，： | 1 |
| 9 | Uptake and translocation of arsenite and arsenate by Pteris vittata L.: Effects of silicon, boron and mercury显示文摘 | Xin Wang Lena Q. Ma Bala Rathinasabapathi Yunguo Liu Guangming Zeng | 2009 | Environmental and Experimental Botany2009，，2： | 1 |
| 10 | Active canopy sensor-based precision N management strategy for rice显示文摘 | Yinkun Yao Yuxin Miao Shanyu Huang Lei Gao Xiaobo Ma Guangming Zhao Rongfeng Jiang Xinping Chen Fusuo Zhang Kang Yu Martin Gnyp Georg Bareth Cheng Liu Liqin Zhao Wen Yang Huamin Zhu | 2012 | Agronomy for Sustainable Development2012，，4： | 1 |
| 11 | Characteristics and mechanisms of the annual asymmetry of thermospheric mass density显示文摘在这份报纸,全球性平均, thermospheric 总数团密度,在从 1967 ~ 2006 被追踪的 250, 400,和 550 km 源于 5000 个目标的轨道,习惯于份量上学习 thermospheric 质量的年度不对称现象密度和它的机制。结果证明那 thermospheric 团密度有重要年度不对称现象,它从年改变了到年。在三高度的年度不对称现象同时地变化了,它的绝对值与高度增加了。结果建议在被差别在一年以内在在二至和太阳的活动的随机的变化之间的太阳地球远处引起的太阳的 EUV 放射有年度不对称现象。在在在 thermospheric 温度并且这样的一个年度变化的放射结果的这个变化中立气体的规模高度,并且是 thermospheric 质量的年度不对称现象的主要原因密度。因为变化的积累的效果,集体密度的年度不对称现象在垂直方向在中立温度和规模高度与高度增加。 | MA RuiPing XU JiYao WANG WenBin CHEN GuangMing YUAN Wei LEI JiuHou Alan G BURNS JIANG GuoYing | 2015 | Science China Earth Sciences2015，58，4： | 1 |
| 12 | WEEE recovery strategies and the WEEE treatment status in China 显示文摘 | He Wenzhi Li Guangming Ma Xingfa | 2006 | Journal of Hazardous Materials2006，，136： | 1 |
| 13 | WEEE recovery strate- gies and the WEEE treatment status in China 显示文摘 | Wenzhi He Guangming Li Xingfa Ma | 2006 | Journal of Haz- ardous Materials2006，136，3： | 1 |
| 14 | Regulation of NAD(H) pool and NADH/NAD + ratio by overexpression of nicotinic acid phosphoribosyltransferase for succinic acid production in Escherichia coli NZN111显示文摘 | Liya Liang Rongming Liu Guangming Wang Dongmei Gou Jiangfeng Ma Kequan Chen Min Jiang Ping Wei Pingkai Ouyang | 2012 | Enzyme and Microbial Technology2012，，5： | 1 |
| 15 | Characterizing noise correlation and enhancing coherence via qubit motion显示文摘The identification of spacial noise correlation is of critical importance in developing error-corrected quantum devices,but it has barely been studied so far.In this work,we utilize an effective method called qubit motion,to efficiently determine the noise correlations between any pair of qubits in a 7-qubit superconducting quantum system.The noise correlations between the same pairs of qubits are also investigated when the qubits are at distinct operating frequencies.What’s more,in this multi-qubit system with the presence of noise correlations,we demonstrate the enhancing effect of qubit motion on the coherence of logic qubits,and we propose a Motion-CPMG operation sequence to more efficiently protect the logic state from decoherence,which is experimentally demonstrated to extend the coherence time of logic qubits by nearly one order of magnitude. | Jiaxiu Han Zhiyuan Li Jingning Zhang Huikai Xu Kehuan Linghu Yongchao Li Chengyao Li Mo Chen Zhen Yang Junhua Wang Teng Ma Guangming Xue Yirong Jin Haifeng Yu | 2021 | Fundamental Research2021，1，1： | 1 |
| 16 | Influence of ultrasonic field on microcystins produced by bloom-forming algae显示文摘 | Bozhi Ma Yifang Chen Hongwei Hao Minsheng Wu Bo Wang Honggang Lv Guangming Zhang | 2004 | Colloids and Surfaces B: Biointerfaces2004，，2： | 1 |
| 17 | Development of a fine-grained microstructure and the properties of a nugget zone in friction stir welded pure copper 显示文摘 | Xie Guangming Ma Zongyi Geng Lin | 2007 | Scripta Mater2007，57，： | 1 |
| 18 | WEEE recovery strategies and the WEEE treatment status in China显示文摘 | He Wenzhi Li Guangming Ma Xingfa | 2006 | Journal of Hazardous Materials2006，136，3： | 1 |
| 19 | An erbium-doped fibre nonlinear coupler with coupling ratios controlled by pump power 显示文摘 | Li Chunfei Xu Guangming Ma Liansheng | 2005 | Journal of Optics A : Pure and Applied Optics2005，7，10： | 1 |
| 20 | Deformation and mechanism of landslide influenced by the effects of reservoir water and rainfall, Three Gorges, China显示文摘 | XIA Min REN Guangming MA Xinlei | 2013 | Natural Hazards2013，68，2： | 1 |
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