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| 1 | Spatial and temporal distribution of Neolithic sites in coastal China:Sea level changes, geomorphic evolution and human adaption显示文摘The East China coastal plain is one of the most important Neolithic culture areas in China, where rich archaeological sites including those producing the earliest domesticated rice are observed. It is also a place where landscape has experienced dramatic evolution during the Holocene when both sea level and climate changed, such that it is an ideal place for studying human-environment interaction. This study investigated over 2000 sites of pre-history and Shang and Zhou Dynasties, with 655 of which being Neolithic ages, by using DEM and GIS methods. The results suggest that the spatial and temporal distribution of Neolithic sites has largely been controlled by landscape evolution(particularly changes in coastal line), which ultimately governed by sea level changes. During early Holocene, Neolithic sites sparsely distributed in the intermountain basins of east Zhejiang Province, far from the influence of ocean. Over the period of 9–7 ka, the coastal plain(including the shelf) was largely submerged,only the feet of low hills to the south and southwest of the study area, and islands protruding the estuary, cradled limited number of settlements with characteristic 'maritime components'. At about 7 ka, sea level rise decelerated prominently, while sediments supply in the drainage remained high value, the combination of which led to land formation and propagation. Vast space during this period facilitated the growth of settlements in both size and number. In the mean time, however, the coastal plain was vulnerable to extreme environmental events such as storms and flooding owning to its geomorphic nature, which exerted great influence on the rise and fall of Neolithic culture. | ZHENG HongBo ZHOU YouSheng YANG Qing HU ZhuJun LING GuangJiu ZHANG JuZhong GU ChunGuang WANG YingYing CAO YeTing HUANG XianRong CHENG Yue ZHANG XiaoYu WU WenXiang | 2018 | Science China Earth Sciences2018，61，2： | 7 |
| 2 | Quantificational indexes for design and evaluation of copper staves for blast furnaces显示文摘The quantificational and normative design is the precondition of improving the design of copper staves for blast furnaces. Based on a 3-dimensional temperature field calculation model,from the view point of heat transfer and long campaigns note with the core of forming accretion,the forming-accretion-ability(FAA)and the rib hot surface maximum temperature difference(ΔT_(max))as quantificational indexes to direct and evaluate the design of copper staves for blast furnaces were presented.The application of the two indexes in design essentially embodies the new long campaigns in the stage of design.With the application of the two indexes, good results can be obtained.Firstly,it was suggested that the rib height of a copper stave can be reduced to 15 mm,which is a new method and theory for the reduction of copper staves.Secondly,the influence of insert on FAA andΔT_(max)is decided by the volume of insert.According to this,the principle of design for the hot surface geometry of copper staves was put forward that the ratio of the rib hot surface to the copper stave hot surface(abbreviated as the ratio of rib to stave)must be maintained in the range of 45% to 55%; for the present copper stave with a 35-40 mm thick rib,the ratio of rib to stave in the range of 50% to 55% can optimize the design of copper staves;for the copper stave with a smaller rib thickness,for example 15 mm,the ratio of rib to stave in the range of 45% to 50% can optimize the design of copper staves.It can be summarized that the thicker the rib thickness,the larger is the ratio of rib to stave. | Liang Qian Susen Cheng Hongbo Zhao | 2008 | Journal of University of Science and Technology Beijing2008，15，1： | 6 |
| 3 | Straw strip mulching in a semiarid rainfed agroecosystem achieves winter wheat yields similar to those of full plastic mulching by optimizing the soil hydrothermal regime显示文摘Straw strip mulching(SM)is a new mulching technology.From 2012 to 2018,SM’s effects on soil moisture and temperature and production performances were compared with other mulching practices,using three treatments:full-cover plastic mulch(PM),no mulch with wheat sown in rows as the control(CK),and SM with 50%to 59%of the field area mulched.Compared with CK,on average over six growing seasons,SM and PM increased grain yield by 27.0%and 21.7%,straw yield by 21.6%and 22.6%,kernels ha;by 26.6%and 19.0%,net income by 29.8%and-25.0%,soil temperature at 5 cm by-1.5°C and 0.2°C from overwintering to maturity,and soil water storage at 0–200 cm by 25 and 22 mm,respectively.The increase in soil moisture in SM and PM was greater in the early period(overwintering to jointing)than in the later period(booting to maturity)and at 0 to 120 cm than at 120–200 cm in the early period.Although the mean evapotranspiration of whole growth period across six seasons was similar among treatments,SM and PM increased water consumption during the key formation period of yield components after overwintering by 16 and 32 mm,respectively,while reducing it before overwintering.Compared with CK,SM and PM had the effects of warming during overwintering and cooling after jointing.By increasing water consumption after overwintering and ratio of transpiration to evapotranspiration and providing favorable soil temperature for multiple growth stages and more sufficient soil moisture,SM and PM promoted vegetative growth and increased kernels ha^(-1),the main mechanisms by which SM and PM increased grain yield relative to CK.Relative to PM,SM is a more economically beneficial and environment-friendly technology for dryland wheat production. | Yuwei Chai Qiang Chai Rui Li Yawei Li Changgang Yang Hongbo Cheng Lei Chang Shouxi Chai | 2022 | The Crop Journal2022，10，3： | 6 |
| 4 | Core-shell structured MoS_2@S spherical cathode with improved electrochemical performance for lithium-sulfur batteries显示文摘To suppress shuttling effect and improve electrochemical performance of the sulfur cathode for lithiumsulfur batteries, core-shell structured MoS_2 @S spherical cathode has been synthesized through a chemical route using MnC03 as template. The MoS_2 shells consist of MoS_2 nanosheets. For comparison, MoS_2/S cathode has also been synthesized through melting and diffusion of sulfur to commercial MoS_2 powders. The electrochemical performance of the MoS_2@S and MoS_2/S cathodes have been evaluated using cyclic voltammetry, discharge/charge cycling, electrochemical impedance spectroscopy coupled with impedance fitting. The electrochemical performance of the MoS_2@S spherical cathode has been much improved compared with that of MoS_2/S. The capacity of the MoS_2@S spheres can reach 1185.7 mAhg-1 at 0.2 C and 955.1 mAhg^(-1) at 1 C with initial-cycle coulombic efficiency of 90%. The capacity fading of each cycle is 0.1 % during 200 lithiation/delithiation cycles. The MoS_2@S spherical cathode with high cyclic capacity and stability is promising cathode candidate for lithium-sulfur batteries. | Songpu Cheng Xiaohong Xia Hongbo Liu Yuxi Chen | 2018 | Journal of Materials Science & Technology2018，34，10： | 5 |
| 5 | Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts显示文摘Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,which even result in dysfunction and death.Vascular regeneration or artificial vascular graft,as the conventional treatment modality,has received keen attentions.However,small-diameter(diameter<4 mm)vascular grafts have a high risk of thrombosis and intimal hyperplasia(IH),which makes long-term lumen patency challengeable.Endothelial cells(ECs)form the inner endothelium layer,and are crucial for anti-coagulation and thrombogenesis.Thus,promoting in situ endothelialization in vascular graft remodeling takes top priority,which requires recruitment of endothelia progenitor cells(EPCs),migration,adhesion,proliferation and activation of EPCs and ECs.Chemotaxis aimed at ligands on EPC surface can be utilized for EPC homing,while nanofibrous structure,biocompatible surface and cell-capturing molecules on graft surface can be applied for cell adhesion.Moreover,cell orientation can be regulated by topography of scaffold,and cell bioactivity can be modulated by growth factors and therapeutic genes.Additionally,surface modification can also reduce thrombogenesis,and some drug release can inhibit IH.Considering the influence of macrophages on ECs and smooth muscle cells(SMCs),scaffolds loaded with drugs that can promote M2 polarization are alternative strategies.In conclusion,the advanced strategies for enhanced long-term lumen patency of vascular grafts are summarized in this review.Strategies for recruitment of EPCs,adhesion,proliferation and activation of EPCs and ECs,anti-thrombogenesis,anti-IH,and immunomodulation are discussed.Ideal vascular grafts with appropriate surface modification,loading and fabrication strategies are required in further studies. | Yu Zhuang Chenglong Zhang Mengjia Cheng Jinyang Huang Qingcheng Liu Guangyin Yuan Kaili Lin Hongbo Yu | 2021 | Bioactive Materials2021，6，6： | 5 |
| 6 | Genome architecture and tetrasomic inheritance of autotetraploid potato显示文摘Potato(Solanum tuberosum)is the most consumed non-cereal food crop.Most commercial potato cultivars are autotetraploids with highly heterozygous genomes,severely hampering genetic analyses and improvement.By leveraging the state-of-the-art sequencing technologies and polyploid graph binning,we achieved a chromosome-scale,haplotype-resolved genome assembly of a cultivated potato,Cooperation-88(C88).lntra-haplotype comparative analyses revealed extensive sequence and expression differences in this tetraploid genome.We identified haplotype-specific pericentromeres on chromosomes,suggesting a distinct evolutionary trajectory of potato homologous centromeres.Furthermore,we detected double reduction events that are unevenly distributed on haplotypes in 1021 of 1034 selfing progeny,a feature of autopolyploid inheritance.By distinguishing maternal and paternal haplotype sets in C88,we simulated the origin of heterosis in cultivated tetraploid with a survey of 3110 tetra-allelic loci with deleterious mutations,which were masked in the heterozygous condition bytwo parents.This study provides insights into the genomic architecture of autopolyploids and will guide their breeding. | Zhigui Bao Canhui Li Guangcun Li Pei Wang Zhen Peng Lin Cheng Hongbo Li Zhiyang Zhang Yuying Li Wu Huang Mingwang Ye Daofeng Dong Zhukuan Cheng Peter VanderZaag Evert Jacobsen Christian W.B.Bachem Suomeng Dong Chunzhi Zhang Sanwen Huang Qian Zhou | 2022 | Molecular Plant2022，15，7： | 4 |
| 7 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 8 | Speech recognition algorithm based on neural network and hidden Markov model显示文摘This study proposes a hybrid model of speech recognition parallel algorithm based on hidden Markov model( HMM) and artificial neural network( ANN). First,the algorithm uses HMM for time-series modeling of speech signals and calculates the voice to the HMM of the output probability score. Second,with the probability score as input to the neural network,the algorithm gets information for classification and recognition and makes a decision based on the hybrid model. Finally,Matlab software is used to train and test sample data. Simulation results show that using the strong time-series modeling ability of HMM and the classification features of the neural network,the proposed algorithm possesses stronger noise immunity than the traditional HMM. Moreover,the hybrid model corrects the individual flaws of the HMM and the neural network,and greatly improves the speed and performance of speech recognition. | Zhao Jianhui Gao Hongbo Liu Yuchao Cheng Bo | 2018 | The Journal of China Universities of Posts and Telecommunications2018，25，4： | 4 |
| 9 | Autonomous parking control for intelligent vehicles based on a novel algorithm显示文摘Along with the increasing number of vehicles, parking space becomes narrow gradually, safety parking puts forward higher requirements on the driver's driving technology. How to safely, quickly and accurately park the vehiclo to parking space right? This paper presents an automatic parking scheme based on trajectory planning, which analyzing the mechanical model of the vehicle, establishing vehicle steering model and parking model, coming to the conclusion that it is the turning radius is independent of the vehicle speed at low speed. The Matlab simulation environment verifies the correctness and effectiveness of the proposed algorithm for parking. A class of the automatic parking problem of intelligent vehicles is solved. | Gao Hongbo Xie Guotao Zhang Xinyu Cheng Bo | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，4： | 3 |
| 10 | Energy-Performance Tradeoffs in laaS Cloud with Virtual Machine Scheduling显示文摘In the cloud data centers,how to map virtual machines(VMs) on physical machines(PMs) to reduce the energy consumption is becoming one of the major issues,and the existing VM scheduling schemes are mostly to reduce energy consumption by optimizing the utilization of physical servers or network elements.However,the aggressive consolidation of these resources may lead to network performance degradation.In view of this,this paper proposes a two-stage VM scheduling scheme:(1) We propose a static VM placement scheme to minimize the number of activating PMs and network elements to reduce the energy consumption;(2) In the premise of minimizing the migration costs,we propose a dynamic VM migration scheme to minimize the maximum link utilization to improve the network performance.This scheme makes a tradeoff between energy efficiency and network performance.We design a new twostage heuristic algorithm for a solution,and the simulations show that our solution achieves good results. | DONG Jiankang WANG Hongbo CHENG Shiduan | 2015 | China Communications2015，12，2： | 3 |
| 11 | Comprehensive profiling of EBV gene expression in nasopharyn- geal carcinoma through paired-end transcriptome sequencing显示文摘在鼻咽的癌(NPC ) 的 Epstein-Barr 病毒(EBV ) 基因的潜伏的表示模式广泛地被调查了,并且在 NPC 的几 lysin 的基因的表示被报导了。然而,通过在 NPC 的 EBV transcriptome 分析的全面信息是有限的。我们执行了对结束 RNA-seq 到系统地并且包括地在 NPC 织物和 C666-1 NPC 房间线描绘 EBV 基因的表示,它一致地带 EBV。除了限制打 II 潜伏感染,类型 III 潜伏 EBNA3s 基因和lysin 的基因的一个实质的数字的抄本,例如 BZLF1 , BRLF1 ,和 BMRF1 ,通过 RNA-seq 被检测并且进一步通过也执行的实时 PCR.We 在 C666-1 房间和 NPC 织物被验证聚类分析以 EBV 基因表示分类 NPC 耐心的组,它介绍了 NPC 样品的二种子类型。结果在 NPC 病人揭示了 EBV 基因表示的有趣的模式。这个聚类与 heterotrimeric G 蛋白质发信号有关与许多发信号的小径被相关,例如那些,发炎由 chemokine 并且 cytokine 发信号调停了,核糖体,蛋白质新陈代谢,流行性感冒感染,和 ECM 受体相互作用。我们的联合调查结果建议在 NPC 的 EBV 基因的表示被限制不仅打 II 潜伏基因而且打 III 潜伏和 lysin 的基因。这研究在 NPC 的发展提供了进一步的卓见进 EBV 的潜在的角色。 | Lijuan Hu Zhirui Lin YanhengWu Juqin Dong Bo Zhao Yanbing Cheng Peiyu Huang Lihua Xu Tianliang Xia Dan Xiong Hongbo Wang Manzhi Li Ling Guo Elliott Kieff YixinZeng | 2016 | Frontiers of Medicine2016，10，1： | 3 |
| 12 | Single-cell transcriptomic landscape of human blood cells显示文摘High throughput single-cell RNA-seq has been successfully implemented to dissect the cellular and molecular features underlying hematopoiesis.However,an elaborate and comprehensive transcriptome reference of the whole blood system is lacking.Here,we profiled the transcriptomes of 7551 human blood cells representing 32 immunophenotypic cell types,including hematopoietic stem cells,progenitors and mature blood cells derived from 21 healthy donors.With high sequencing depth and coverage,we constructed a single-cell transcriptional atlas of blood cells(ABC) on the basis of both protein-coding genes and long noncoding RNAs(lncRNAs),and showed a high consistence between them.Notably,putative lncRNAs and transcription factors regulating hematopoietic cell differentiation were identified.While common transcription factor regulatory networks were activated in neutrophils and monocytes,lymphoid cells dramatically changed their regulatory networks during differentiation.Furthermore,we showed a subset of nucleated erythrocytes actively expressing immune signals,suggesting the existence of erythroid precursors with immune functions.Finally,a web portal offering transcriptome browsing and blood cell type prediction has been established.Thus,our work provides a transcriptional map of human blood cells at single-cell resolution,thereby offering a comprehensive reference for the exploration of physiological and pathological hematopoiesis. | Xiaowei Xie Mengyao Liu Yawen Zhang Bingrui Wang Caiying Zhu Chenchen Wang Qing Li Yingying Huo Jiaojiao Guo Changlu Xu Linping Hu Aiming Pang Shihui Ma Una Wang Wenbin Cao Shulian Chen Qiuling Li Sudong Zhang Xueying Zhao Wen Zhou Hongbo Luo Guoguang Zheng Erlie Jiang Sizhou Feng Lixiang Chen Lihong Shi Hui Cheng Sha Hao Ping Zhu Tao Cheng | 2021 | National Science Review2021，8，3： | 3 |
| 13 | Establishment of a rhesus monkey model of middle cerebral artery ischemia and reperfusion using a microcatheter embolization method显示文摘Nonhuman primates are closest to humans in terms of lineage,and middle cerebral artery ischemia/reperfusion responses of nonhuman primates are most similar to ischemic stroke in humans.Therefore,nonhuman primates could be utilized to simulate the process of ischemic stroke in the human.Few studies,however,have reported the use of endovascular technology to establish a rhesus monkey stroke model.In the present study,seven adult,male,rhesus monkeys were selected and,following anesthesia,a microcatheter was inserted into one side of the middle cerebral artery via the femoral artery to block blood flow,thereby resulting in middle cerebral artery occlusion.After 2 hours,the microcatheter was withdrawn to restore the middle cerebral artery blood flow and to establish ischemia/reperfusion.Results from angiography and magnetic resonance angiography confirmed occlusion and reopening of the middle cerebral artery.Magnetic resonance imaging revealed the existence of ischemic brain lesions,and neurological examination showed sustained functional deficits following surgery.The rhesus monkey middle cerebral artery ischemia/reperfusion models established by microcatheter embolization had the advantage of non-craniotomy invasion and reproducibility.The scope and degree of ischemic damage using this model was controllable.Therefore,this nonhuman primate model is an ideal model for cerebral ischemia and reperfusion. | Jie Yang Jian Guo Hongbo Zheng Muke Zhou Li He Wenying Cao Li Xiao Jiachuan Duan Qiyong Gong Xiaoqi Huang Hongxia Li Li Wang Jingqiu Cheng | 2010 | Neural Regeneration Research2010，5，15： | 2 |
| 14 | Modulating intestinal mucus barrier for nanoparticles penetration by surfactants显示文摘Improving peroral delivery efficiency is always a persistent goal for both small-molecule and macromolecular drug development. However,intestinal mucus barrier which greatly impedes drug-loaded nanoparticles penetration is commonly overlooked. Therefore,in this study,taking fluorescent labeled PLGA(poly(lactic-co-glycolic acid)) nanoparticles as a tool,the influence of anionic and nonionic surfactants on mucus penetration ability of nanoparticles and their mucus barrier regulating ability were studied. The movement of PLGA nanoparticles in mucus was tracked by multiple particles tracking method(MPT).Alteration of mucus properties by addition of surfactants was evaluated by rheology and morphology study. Rat intestinal villus penetration study was used to further evaluate penetration enhancement of nanoparticles. The effective diffusivities of the nanoparticles in surfactants pretreated mucus were increased by 2–3 times and the mucus barrier regulating capacity was also surfactant type dependent. Sodium dodecyl sulfate(SDS) increased the complex viscosity and viscoelastic properties of mucus,but poloxamer presented a decreased trend. Tween 80 maintained the rheological property of the mucus. With the mucus barrier regulated by surfactants,the penetration of nanoparticles in intestinal villus was obviously increased. In summary,the mucus penetration ability of nanoparticles could be enhanced by altering mucus microenvironment with surfactants. Tween 80 which largely retains the original mucus rheology and morphology properties may be a promising candidate for facilitating nanoparticle penetration through the mucus barrier with good safety profile. | Xin Zhang Wei Dong Hongbo Cheng Meixia Zhang Yongqiang Kou Jian Guan Qiaoyu Liu Mingyue Gao Xiuhua Wang ShiruiMao | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，5： | 2 |
| 15 | Lipidomic and transcriptomic analysis reveals reallocation of carbon flux from cuticular wax into plastid membrane lipids in a glossy“Newhall”navel orange mutant显示文摘Both cuticle and membrane lipids play essential roles in quality maintenance and disease resistance in fresh fruits.Many reports have indicated the modification of alternative branch pathways in epicuticular wax mutants;however,the specific alterations concerning lipids have not been clarified thus far.Here,we conducted a comprehensive,timeresolved lipidomic,and transcriptomic analysis on the“Newhall”navel orange(WT)and its glossy mutant(MT)“Gannan No.1”.The results revealed severely suppressed wax formation accompanied by significantly elevated production of 36-carbon plastid lipids with increasing fruit maturation in MT.Transcriptomics analysis further identified a series of key functional enzymes and transcription factors putatively involved in the biosynthesis pathways of wax and membrane lipids.Moreover,the high accumulation of jasmonic acid(JA)in MT was possibly due to the need to maintain plastid lipid homeostasis,as the expression levels of two significantly upregulated lipases(CsDAD1 and CsDALL2)were positively correlated with plastid lipids and characterized to hydrolyze plastid lipids to increase the JA content.Our results will provide new insights into the molecular mechanisms underlying the natural variation of plant lipids to lay a foundation for the quality improvement of citrus fruit. | Haoliang Wan Hongbo Liu Jingyu Zhang Yi Lyu Zhuoran Li Yizhong He Xiaoliang Zhang Xiuxin Deng Yariv Brotman Alisdair RFernie Yunjiang Cheng Weiwei Wen | 2020 | Horticulture Research2020，7，1： | 2 |
| 16 | Learning an identity distinguishable space for large scale face recognition显示文摘Implementing face recognition efficiently to real world large scale dataset presents great challenges to existing approaches. The method in this paper was proposed to learn an identity distinguishable space for large scale face recognition in MSR-Bing image recognition challenge( IRC). Firstly,a deep convolutional neural network( CNN)was used to optimize a 128 B embedding for large scale face retrieval. The embedding was trained via using triplets of aligned face patches from Face Scrub and CASIA-Web Face datasets. Secondly,the evaluation of MSR-Bing IRC was conducted according to a cross-domain retrieval scheme. The real-time retrieval in this paper was benefited from the K-means clustering performed on the feature space of training data. Furthermore,a large scale similarity learning( LSSL) was applied on the relevant face images for learning a better identity space. A novel method for selecting similar pairs was proposed for LSSL. Compared with many existing networks of face recognition,the proposed model was lightweight and the retrieval method was promising as well. | Yue Ting Wang Hongbo Cheng Shiduan | 2018 | The Journal of China Universities of Posts and Telecommunications2018，25，1： | 2 |
| 17 | Mesh Smoothing Method Based on Local Wave Analysis显示文摘As the mesh models usually contain noise data,it is necessary to eliminate the noises and smooth the mesh.But existed methods always lose geometric features during the smoothing process.Hence,the noise is considered as a kind of random signal with high frequency,and then the mesh model smoothing is operated with signal processing theory.Local wave analysis is used to deal with geometric signal,and then a novel mesh smoothing method based on the local wave is proposed.The proposed method includes following steps:Firstly,analyze the principle of local wave decomposition for 1D signal,and expand it to 2D signal and 3D spherical surface signal processing;Secondly,map the mesh to the spherical surface with parameterization,resample the spherical mesh and decompose the spherical signals by local wave analysis;Thirdly,propose the coordinate smoothing and radical radius smoothing methods,the former filters the mesh points' coordinates by local wave,and the latter filters the radical radius from their geometric center to mesh points by local wave;Finally,remove the high-frequency component of spherical signal,and obtain the smooth mesh model with inversely mapping from the spherical signal.Several mesh models with Gaussian noise are processed by local wave based method and other compared methods.The results show that local wave based method can obtain better smoothing performance,and reserve more original geometric features at the same time. | QIN Xujia ZHENG Hongbo CHENG Shiwei LIU Shishuang XU Xiaogang | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 2 |
| 18 | Virtual Machine Scheduling for Improving Energy Efficiency in laaS Cloud显示文摘In IaaS Cloud,different mapping relationships between virtual machines(VMs) and physical machines(PMs) cause different resource utilization,so how to place VMs on PMs to reduce energy consumption is becoming one of the major concerns for cloud providers.The existing VM scheduling schemes propose optimize PMs or network resources utilization,but few of them attempt to improve the energy efficiency of these two kinds of resources simultaneously.This paper proposes a VM scheduling scheme meeting multiple resource constraints,such as the physical server size(CPU,memory,storage,bandwidth,etc.) and network link capacity to reduce both the numbers of active PMs and network elements so as to finally reduce energy consumption.Since VM scheduling problem is abstracted as a combination of bin packing problem and quadratic assignment problem,which is also known as a classic combinatorial optimization and NP-hard problem.Accordingly,we design a twostage heuristic algorithm to solve the issue,and the simulations show that our solution outperforms the existing PM- or network-only optimization solutions. | DONG Jiankang WANG Hongbo LIYangyang CHENG Shiduan | 2014 | China Communications2014，11，3： | 2 |
| 19 | Optimization for the structure of BF hearth bottom and the arrangement of thermal couples显示文摘The hearth of “heat transfer method” and the ceramic cup synthetic hearth bottom of “heart isolation method” are two most popular designs for blast furnace (BF). Although there are successful real examples, some disadvantages, for instance large heat loss and high cost, still exist for these designs. According to the theory of heat transfer, based on the calculation of temperature distribution of the hearth bottom, it is elucidated that all brick layers at the hearth bottom may not be considered as the only reason why different structures exhibited different temperature distributions although total heat resistance is the same, and then based on the effect of hot metal and cold water on different temperature distribution ranges, the concepts of “heat resistance” and “cooling enhancement” are put forth. Based on this, the disadvantages and the factors affecting temperature distribution, of the two types of hearth bottoms were illustrated. On the basis of these analyses, a novel structure for BF hearth bottom designing that can easily form “self-protecting” slag layer stably, called “the method of gradient brick layout that has an optimum combination of cooling enhancement and heat resistance” was proposed; it can not only prolong the hearth bottom longevity but also reduce the cost and heat loss. Also, the optimum arrangement of thermal couples in hearth bottom was suggested based on the previous studies on erosion prediction carried out by the author. | ZHAO Hongbo CHENG Shusen | 2006 | 北京科技大学学报2006，28，12： | 2 |
| 20 | The ZBTB24-CDCA7 axis regulates HELLS enrichment at centromeric satellite repeats to facilitate DNA methylation显示文摘Dear Editor,Immunodeficiency,centromeric instability,and facial anomalies(ICF)syndrome is a rare autosomal recessive disorder characterized by antibody deficiency,facial dysmorphism,failure to thrive,and mental retardation.Patients with ICF syndrome suffer from recurrent and often fatal infections in early childhood.A hallmark of ICF syndrome is loss of DNA methylation in special genomic regions,most notably satellite repeats at centromeric regions,which leads to heterochromatin decondensation and chromosomal abnormalities in lymphocytes(Ehrlich et al.,2008). | Swanand Hardikar Zhengzhou Ying Yang Zeng Hongbo Zhao Bigang Liu Nicolas Veland Kevin McBride Xiaodong Cheng Taiping Chen | 2020 | Protein & Cell2020，11，3： | 2 |
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