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| 1 | Targeting NF-κB pathway for the therapy of diseases:mechanism and clinical study显示文摘NF-κB pathway consists of canonical and non-canonical pathways.The canonical NF-κB is activated by various stimuli,transducing a quick but transient transcriptional activity,to regulate the expression of various proinflammatory genes and also serve as the critical mediator for inflammatory response.Meanwhile,the activation of the non-canonical NF-κB pathway occurs through a handful of TNF receptor superfamily members.Since the activation of this pathway involves protein synthesis,the kinetics of non-canonical NF-κB activation is slow but persistent,in concordance with its biological functions in the development of immune cell and lymphoid organ,immune homeostasis and immune response.The activation of the canonical and non-canonical NF-κB pathway is tightly controlled,highlighting the vital roles of ubiquitination in these pathways.Emerging studies indicate that dysregulated NF-κB activity causes inflammation-related diseases as well as cancers,and NF-κB has been long proposed as the potential target for therapy of diseases.This review attempts to summarize our current knowledge and updates on the mechanisms of NF-κB pathway regulation and the potential therapeutic application of inhibition of NF-κB signaling in cancer and inflammatory diseases. | Hui Yu Liangbin Lin Zhiqiang Zhang Huiyuan Zhang Hongbo Hu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 35 |
| 2 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012，22，3： | 18 |
| 3 | Properties and characterization of Au^(3+)-adsorption by mycelial waste of Streptomyces aureofaciences显示文摘Mycelial waste of Streptomyces aureofaciences procured from the aureomycin fermentation industry is used as biosorbent for Au3+. The properties of Au3+ adsorption by the mycelial waste are studied. The results indicate that the optimum pH value of Au3+ adsorption is 3.5. The biosorption is a rapid and non-temperature-dependent process. The bio-sorptive capacity with 45.6 mg/g and efficiency with 91.2% are achieved under the conditions of pH 3.5 and 30℃ for 45 min, in which the ratio is 50 mg/g dry weight for the concentrations of initial Au3+ and the mycelial waste. The Au3+ ions adsorbed on the mycelial waste can be eluted. The observation in a transmission electron microscope shows that the Au3+ ions can be reduced to Au particles by the mycelial waste and the Au can become gold crystals with differentforms and sizes. X-ray photoelectron spectroscopy analysis further proves that the Au3+ can be reduced to Au0 by the mycelial waste. | LIU Yueying, FU Jinkun, HU Hongbo, TANG Dingliang, Nl Zimian & YU Xinsheng1. Department of Biology, 2. State Key Laboratory for Physical Chemistry of Solid Surface, 3. Center for Analysis & Testing, Xiamen University, Xiamen 361005, China | 2001 | Chinese Science Bulletin2001，46，20： | 15 |
| 4 | Kinematics and Dynamics Analysis of a Quadruped Walking Robot with Parallel Leg Mechanism显示文摘It is desired to require a walking robot for the elderly and the disabled to have large capacity,high stiffness,stability,etc.However,the existing walking robots cannot achieve these requirements because of the weight-payload ratio and simple function.Therefore,Improvement of enhancing capacity and functions of the walking robot is an important research issue.According to walking requirements and combining modularization and reconfigurable ideas,a quadruped/biped reconfigurable walking robot with parallel leg mechanism is proposed.The proposed robot can be used for both a biped and a quadruped walking robot.The kinematics and performance analysis of a 3-UPU parallel mechanism which is the basic leg mechanism of a quadruped walking robot are conducted and the structural parameters are optimized.The results show that performance of the walking robot is optimal when the circumradius R,r of the upper and lower platform of leg mechanism are 161.7 mm,57.7 mm,respectively.Based on the optimal results,the kinematics and dynamics of the quadruped walking robot in the static walking mode are derived with the application of parallel mechanism and influence coefficient theory,and the optimal coordination distribution of the dynamic load for the quadruped walking robot with over-determinate inputs is analyzed,which solves dynamic load coupling caused by the branches' constraint of the robot in the walk process.Besides laying a theoretical foundation for development of the prototype,the kinematics and dynamics studies on the quadruped walking robot also boost the theoretical research of the quadruped walking and the practical applications of parallel mechanism. | WANG Hongbo SANG Lingfeng HU Xing ZHANG Dianfan YU Hongnian | 2013 | Chinese Journal of Mechanical Engineering2013，26，5： | 12 |
| 5 | Recent advances in gecko adhesion and friction mechanisms and development of gecko-inspired dry adhesive surfaces显示文摘The remarkable ability of geckos to climb and run rapidly on walls and ceilings has recently received considerable interest from many researchers.Significant progress has been made in understanding the attachment and detachment mechanisms and the fabrication of articulated gecko-inspired adhesives and structured surfaces.This article reviews the direct experiments that have investigated the properties of gecko hierarchical structures,i.e.,the feet,toes,setae,and spatulae,and the corresponding models to ascertain the mechanical principles involved.Included in this review are reports on gecko-inspired surfaces and structures with strong adhesion forces,high ratios of adhesion and friction forces,anisotropic hierarchical structures that give rise to directional adhesion and friction,and“intelligent”attachment and detachment motions. | Ming ZHOU Noshir PESIKA Hongbo ZENG Yu TIAN Jacob ISRAELACHVILI | 2013 | Friction2013，1，2： | 12 |
| 6 | Detection of a half-microgal coseismic gravity change after the Ms7. 0 Lushan earthquake显示文摘Because only a small near-field coseismic gravity change signal remains after removal of noise from the accuracy of observations and the time and spatial resolution of the earth's surface gravity observation system,it is difficult to verify simulations of dislocation theory.In this study,it is shown that the GS15 gravimeter,located 99.5 km from the epicenter of the Ms7.0 Lushan earthquake on April 20,2013 at 08∶04 UTC+8,showed the influence of the earthquake from 2013-04-16 to 2013-04-26 after a time calibration,tide corrections,drift correction,period correction and relaxation correction were applied to its data.The post-seismic relaxation process of the spring in the gravimeter took approximately 430 minutes and showed a 2.5×10-8ms-2gravity change.After correcting for the relaxation process,it is shown that a coseismic gravity change of approximately+0.59±0.4×10-8ms-2was observed by the GS15 gravimeter;this agrees with the simulated gravity change of approximately 0.31×10-8ms-2.The rate of the coseismic gravity change and the coseismic vertical displacement,as measured by one-second and one-day sampling interval GPS units,is also consistent with the theoretical rate of change.Therefore,the GS15 gravimeter at the Pixian Station observed a coseismic gravity change after the Ms7.0 Lushan earthquake.This and similar measurements could be applied to test and confirm the theory used for these simulations. | Wei Jin Zhao Bin Tan Hongbo Yu Dan Shen Chongyang Li Hui | 2013 | Geodesy and Geodynamics2013，4，3： | 7 |
| 7 | La/Ce-codoped Bi_2O_3 composite photocatalysts with high photocatalytic performance in removal of high concentration dye显示文摘A series of La/Ce-codoped Bi_2O_3 composite photocatalysts were fabricated via hydrothermal–calcination process. The as-prepared products were intensively characterized by some physicochemical characterizations like N_2 physical adsorption, X-ray powder diffraction(XRD), scanning electron microscope(SEM), transmission electron microscope(TEM), UV–Vis diffuse reflectance(UV–Vis DRS), Fourier transform infrared spectroscopy(FT-IR),photoelectrochemical measurements, and photoluminescence(PL) spectroscopy. The characterization results indicated that La and Ce doping induced obvious crystal phase transformation in Bi_2O_3, from monoclinic to tetragonal phase. La and Ce codoping also gave rise to the obvious synergetic effects, e.g., the lattice contraction of Bi_2O_3, the decrease of crystal size and the increase of surface area. The photocatalytic performance of the prepared catalysts was evaluated by removal of dye acid orange II with high concentration under visible light irradiation. Results showed that La/Ce-codoped Bi_2O_3 displayed much higher photocatalytic performance than that of bare Bi_2O_3, single La or Ce doped Bi_2O_3 samples. The superior photocatalytic activity was mainly attributed to the improved texture and surface properties and the synergistic effects of La and Ce codoping on suppressing the recombination of photo-generated electrons(e^-) and holes(h^+). | Shuangshuang Xue Hongbo He Qizhe Fan Changlin Yu Kai Yang Weiya Huang Yang Zhou Yu Xie | 2017 | Journal of Environmental Sciences2017，29，10： | 7 |
| 8 | A novel RHT-TBD approach for weak targets in HPRF radar显示文摘A novel approach, which can handle ambiguous data from weak targets, is proposed within the randomized Hough transform track-before-detect(RHT-TBD) framework. The main idea is that, without the pre-detection and ambiguity resolution step at each time step, the ambiguous measurements are mapped by the multiple hypothesis ranging(MHR) procedure. In this way, all the information, based on the relativity in time and pulse repetition frequency(PRF) domains, can be gathered among different PRFs and integrated over time via a batch procedure. The final step is to perform the RHT with all the extended measurements, and the ambiguous data is unfolded while the detection decision is confirmed at the end of the processing chain.Unlike classic methods, the new approach resolves the problem of range ambiguity and detects the true track for targets. Finally, its application is illustrated to analyze and compare the performance between the proposed approach and the existing approach. Simulation results exhibit the effectiveness of this approach. | Hongbo YU Guohong WANG Wei WU Shuncheng TAN | 2016 | Science China Earth Sciences2016，59，12： | 6 |
| 9 | Oxyvanite V3O5:A new intercalation-type anode for lithium-ion battery显示文摘In the present study,V3O5 microcrystals that synthesized via vacuum calcination are employed as anodes for lithium-ion batteries(LIBs)for the first time.Despite the widely observed sluggish reaction kinetics and poor cycling stability in most microsized transition metal oxides,the V3O5 microcrystals exhibit excellent rate capability(specific capacities of 144 and 125 mAh g^−1 are achieved at extremely high current densities of 20 and 50 A g^−1,respectively)and long-term cycling performance(specific capacity of 117 mAh g^−1 is sustained over 2000 cycles at 50 A g^−1).It is ascribed to the three-dimensional open-framework structure of the V3O5 microcrystals as a major factor in dictating the fast reaction kinetics(lithium diffusion coefficient:~10−9 cm^2 s^−1).In addition,significant insight into the reaction mechanism of the V3O5 microcrystals in concomitant its phase evolution are obtained from ex-situ XRD study,revealing that the V3O5 microcrystals undergo intercalation reaction with insignificant structural change in response to lithiation/delithiation. | Dong Chen Huiteng Tan Xianhong Rui Qi Zhang Yuezhan Feng Hongbo Geng Chengchao Li Shaoming Huang Yan Yu | 2019 | InfoMat2019，1，2： | 6 |
| 10 | Joint range ambiguity resolving and multiple maneuvering targets tracking in clutter via MMPHDF-DA显示文摘It is difficult to track multiple maneuvering targets of which the number is unknown and timevarying,especially when there is range ambiguity.The random finite sets(RFS)based probability hypothesis density filter(PHDF)is an effective solution to the problem of multiple targets tracking.However,when tracking multiple targets via the range ambiguous radar,the problem of range ambiguity has to be solved.In this paper,a multiple model PHDF and data association(MMPHDF-DA)based method is proposed to address multiple maneuvering targets tracking with range ambiguous radar in clutter.Firstly,by introducing the turn rate of target and the discrete pulse interval number(PIN)as components of target state vector,and modeling the incremental variable of the PIN as a three-state Markov chain,the problem of multiple maneuvering targets tracking with range ambiguity is converted into a hybrid state filtering problem.Then,by implementing a novel'track-estimate'oriented association with the filtering results of the hybrid filter,target tracks are provided at each time step.Simulation results demonstrate that the MMPHDF-DA can estimate target state as well as the PIN simultaneously,and succeeds in multiple maneuvering target tracking with range ambiguity in clutter.Simulation results also demonstrate that the MMPHDF-DA can overcome the limitation of the Chinese Remainder Theorem for range ambiguity resolving. | TAN ShunCheng WANG GuoHong WANG Na YU HongBo | 2014 | Science China(Information Sciences)2014，57，8： | 6 |
| 11 | A Fusion Based Particle Filter TBD Algorithm for Dim Targets显示文摘A Fusion based particle filter track-beforedetect algorithm(FPF-TBD) is proposed for dealing with dim targets, in which the importance density function of the Particle filter(PF) is generated by means of a fusion algorithm. In order to construct an accurate approximation to the true proposal distribution, the state at each time scan is predicted according to the Extended Kalman filter algorithm(EKF) and the Unscented Kalman filter(UKF) simultaneously. The information, based on the recursion of the weights, is gathered over multiple scans, and the detection decision is made based on tracking results at the end of the processing chain. By making best use of the recent measurements, this new proposed method can obtain an accurate approximation to the system and as a result, improve the track accuracy and detection performance. Simulation results illustrate the effectiveness of this approach. | YU Hongbo WANG Guohong CAO Qian SUN Yun | 2015 | Chinese Journal of Electronics2015，24，3： | 6 |
| 12 | Comparison and analysis of dislocation density, morphology and evolution in microstructure of low-carbon steel produced using different technologies显示文摘Three kinds of specimens were produced from hot strips of similar composition and same thickness (nominal gauge 4.0mm) but produced using different technologies, and the dislocation density of these strips was quantitatively measured by positron annihilation technique test. The dislocation morphology and evolution in microstructure of each pass for producing the 1.9mm hot strip using CSP (compact strip production) technology were observed under an H-800 transmission electron microscope; its density was also quantitatively measured using the positron annihilation technique test, and the factors influencing the dislocation density during the production process were analyzed. The experimental results show that the dislocation density in the microstructure produced using CSP technology is higher than that in the microstructure produced using conventional technology. This result was discussed and confirmed on the basis of the finite element simulation and the theory relevant to dislocations. | YU Hao~ 1) , KANG Yonglin~ 1) , DONG Hongbo~ 2) 1) Materials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China 2) Jinan Iron & Steel Group Co., Jinan 250101, China | 2006 | 北京科技大学学报2006，28，11： | 5 |
| 13 | Operation and Force Analysis of the Guide Wire in a Minimally Invasive Vascular Interventional Surgery Robot System显示文摘To develop a robot system for minimally invasive surgery is significant,however the existing minimally invasive surgery robots are not applicable in practical operations,due to their limited functioning and weaker perception.A novel wire feeder is proposed for minimally invasive vascular interventional surgery.It is used for assisting surgeons in delivering a guide wire,balloon and stenting into a specific lesion location.By contrasting those existing wire feeders,the motion methods for delivering and rotating the guide wire in blood vessel are described,and their mechanical realization is presented.A new resistant force detecting method is given in details.The change of the resistance force can help the operator feel the block or embolism existing in front of the guide wire.The driving torque for rotating the guide wire is developed at different positions.Using the CT reconstruction image and extracted vessel paths,the path equation of the blood vessel is obtained.Combining the shapes of the guide wire outside the blood vessel,the whole bending equation of the guide wire is obtained.That is a risk criterion in the delivering process.This process can make operations safer and man-machine interaction more reliable.A novel surgery robot for feeding guide wire is designed,and a risk criterion for the system is given. | YANG Xue WANG Hongbo SUN Li YU Hongnian | 2015 | Chinese Journal of Mechanical Engineering2015，28，2： | 5 |
| 14 | Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice显示文摘Oxysophoridine, a new alkaloid extracted from Sophora alopecuroides L., has been shown to have a protective effect against ischemic brain damage. In this study, a focal cerebral ischemia/reperfusion injury model was established using middle cerebral artery occlusion in mice. Both 62.5, 125, and 250 mg/kg oxysophoridine, via intraperitoneal injection, and 6 mg/kg nimodipine, via intragastric administration, were administered daily for 7 days before modeling. After 24 hours of reperfusion, mice were tested for neurological deficit, cerebral infarct size was assessed and brain tissue was collected. Results showed that oxysophoridine at 125, 250 mg/kg and 6 mg/kg nimodipine could reduce neurological deficit scores, cerebral infarct size and brain water content in mice. These results provided evidence that oxysophoridine plays a protective role in cerebral ischemia/reperfusion injury. In addition, oxysophoridine at 62.5, 125, and 250 mg/kg and 6 mg/kg nimodipine increased adenosine-triphosphate content, and decreased malondialdehyde and nitric oxide content. These compounds enhanced the activities of glutathione-peroxidase, superoxide dismutase, catalase, and lactate dehydrogenase, and decreased the activity of nitric oxide synthase. Protein and mRNA expression levels of N-methyl-D-aspartate receptor subunit NR1 were markedly inhibited in the presence of 250 mg/kg oxysophoridine and 6 mg/kg nimodipine. Our experimental findings indicated that oxysophoridine has a neuroprotective effect against cerebral ischemia/reperfusion injury in mice, and that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1. | Hongbo Wang Yuxiang Li Ning Jiang Xiaoping Chen Yi Zhang Kuai Zhang Tengfei Wang Yinju Hao Lin Ma Chengjun Zhao Yanrong Wang Tao Sun Jianqiang Yu | 2013 | Neural Regeneration Research2013，8，15： | 5 |
| 15 | Experimental research on rotating detonation with liquid hypergolic propellants显示文摘This paper describes experimental research into the initiation and propagation of rotating detonation for liquid Nitrogen TetrOxide(NTO) and liquid MonoMethylHydrazine(MMH).An annular rocket-type combustor without nozzle was designed to investigate detonation combustion. The propellants were injected through unlike impingement injectors. The combustion flame fronts and pressure waves were detected using optical diagnostics and dynamic pressure sensors,respectively. The propagation of rotating detonation was established spontaneously by increasing the mass flow rate of propellants. The velocity of propagation of the flame fronts and pressure waves was nearly equal and reaches supersonic speed. Two different detonation combustion patterns are present, single wave mode and double waves mode. And in double waves mode, the two detonation waves are always counter-rotating. The possibility of rotating detonation initiation in a combustor with nozzle was also checked. Stable rotating detonation can be initialized and sustained at similar operating conditions. | Shuaijie XUE Hongjun LIU Lixin ZHOU Weidong YANG Hongbo HU Yu YAN | 2018 | Chinese Journal of Aeronautics2018，31，12： | 5 |
| 16 | Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts显示文摘Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,which even result in dysfunction and death.Vascular regeneration or artificial vascular graft,as the conventional treatment modality,has received keen attentions.However,small-diameter(diameter<4 mm)vascular grafts have a high risk of thrombosis and intimal hyperplasia(IH),which makes long-term lumen patency challengeable.Endothelial cells(ECs)form the inner endothelium layer,and are crucial for anti-coagulation and thrombogenesis.Thus,promoting in situ endothelialization in vascular graft remodeling takes top priority,which requires recruitment of endothelia progenitor cells(EPCs),migration,adhesion,proliferation and activation of EPCs and ECs.Chemotaxis aimed at ligands on EPC surface can be utilized for EPC homing,while nanofibrous structure,biocompatible surface and cell-capturing molecules on graft surface can be applied for cell adhesion.Moreover,cell orientation can be regulated by topography of scaffold,and cell bioactivity can be modulated by growth factors and therapeutic genes.Additionally,surface modification can also reduce thrombogenesis,and some drug release can inhibit IH.Considering the influence of macrophages on ECs and smooth muscle cells(SMCs),scaffolds loaded with drugs that can promote M2 polarization are alternative strategies.In conclusion,the advanced strategies for enhanced long-term lumen patency of vascular grafts are summarized in this review.Strategies for recruitment of EPCs,adhesion,proliferation and activation of EPCs and ECs,anti-thrombogenesis,anti-IH,and immunomodulation are discussed.Ideal vascular grafts with appropriate surface modification,loading and fabrication strategies are required in further studies. | Yu Zhuang Chenglong Zhang Mengjia Cheng Jinyang Huang Qingcheng Liu Guangyin Yuan Kaili Lin Hongbo Yu | 2021 | Bioactive Materials2021，6，6： | 5 |
| 17 | A Joint Learning Framework for the CCKS-2020 Financial Event Extraction Task显示文摘This paper presents a winning solution for the CCKS-2020 financial event extraction task, where the goal is to identify event types, triggers and arguments in sentences across multiple event types. In this task, we focus on resolving two challenging problems(i.e., low resources and element overlapping) by proposing a joint learning framework, named SaltyFishes. We first formulate the event extraction task as a joint probability model. By sharing parameters in the model across different types, we can learn to adapt to low-resource events based on high-resource events. We further address the element overlapping problems by a mechanism of Conditional Layer Normalization, achieving even better extraction accuracy. The overall approach achieves an F1-score of 87.8% which ranks the first place in the competition. | Jiawei Sheng Qian Li Yiming Hei Shu Guo Bowen Yu Lihong Wang Min He Tingwen Liu Hongbo Xu | 2021 | Data Intelligence2021，3，3： | 4 |
| 18 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 19 | Virtual network function scheduling via multilayer encoding genetic algorithm with distributed bandwidth allocation显示文摘Network function virtualization represents a revolutionary approach to network service deployment. This software-oriented approach for virtual network functions(VNFs) deployment enables more flexible and dynamic network services to meet diversified demands. To minimize the execution time of all VNFs in service function chains, VNF scheduling must be addressed. In this paper, we improve upon the flexible job-shop model by introducing the process of bandwidth allocation. First, we propose a multilayer encoding genetic algorithm to solve the VNF scheduling model. In addition, we design a distributed method for bandwidth allocation based on the Nash bargaining solution. Finally, by combining the genetic algorithm with distributed bandwidth allocation, we present a heuristic algorithm that solves the VNF scheduling problem in one stage. Using a multilayer encoding genetic algorithm, we simplify the constraints of the VNF scheduling problem and reduce its time complexity. At the same time, our Nash game solution refines the granularity of bandwidth allocation to further reduce the transmission delay between VNFs. The effectiveness of our proposed heuristic algorithm is verified through numerical evaluation. Compared with existing approaches,our method exhibits shorter scheduling time and reduces CPU time by 45% in simulated scenarios. | Quan YUAN Hongbo TANG Wei YOU Xiaolei WANG Yu ZHAO | 2018 | Science China(Information Sciences)2018，61，9： | 4 |
| 20 | Evaluate the security margins of SHA-512, SHA-256and DHA-256 against the boomerang attack显示文摘For an n-bit random permutation, there are three types of boomerang distinguishers, denoted as Type I, II and III, with generic complexities 2~n, 2^(n/3) and 2^(n/2) respectively. In this paper, we try to evaluate the security margins of three hash functions namely SHA-512, SHA-256 and DHA-256 against the boomerang attack.Firstly, we give a boomerang attack on 48-step SHA-512 with a practical complexity of 2^(51). The correctness of this attack is verified by providing a Type III boomerang quartet. Then, we extend the existing differential characteristics of the three hash functions to more rounds. We deduce the sufficient conditions and give thorough evaluations to the security margins as follows: Type I boomerang method can attack 54-step SHA-512, 51-step SHA-256 and 46-step DHA-256 with complexities 2^(480), 2^(218) and 2^(236) respectively. Type II boomerang method can attack 51-step SHA-512, 49-step SHA-256 and 43-step DHA-256 with complexities 2^(158.50), 2^(72.91) and 2^(74.50) respectively. Type III boomerang method can attack 52-step SHA-512, 50-step SHA-256 and 44-step DHA-256 with complexities 2^(223.80), 2^(123.63) and 2^(99.85) respectively. | Hongbo YU Yonglin HAO Dongxia BAI | 2016 | Science China(Information Sciences)2016，59，5： | 3 |
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