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	题名	作者	年代	出处	被引量
1	Cultivation of human liver cell lines with microcarriers acting as biological materials of bioartificial liver显示文摘AIM To improve the Cultivation efficiency and yield of human liver cell line CL--l.METHODS High--density cultivation of CL--l onmicrocarriers was carried out with periodicobservation of their growth and proliferation.The specific functions of human liver cell werealso determined.RESULTS Cells of CL-1 cell line grew well onmicrocarrier Cytodex--3 and on the 7th day thepeak was reached. The amount of CLI cells was2.13 x 10’ and the total amount of albuminsynthesis reached 71 .23 ig, urea synthesis23 .32 mg and diazepam transformation 619 .7 ugrespectively. The yield of CL-l on microcarrierswas 49.3 times that of conventional cultivation.The amounts of albumin synthesis, ureasynthesis and diazepam transformation were39.8 times, 41 .6 times and 33.3 times those ofconventional Cultivation, respectively.CONCLUSION The human liver cell line CL--1 canbe Cultivated to a high density with Cytodex--3and has better biological functions. High-densityCultivation of CLI on microcarriers can act asthe biological material of bioartificial liver.	Gao Y Xu XP Hu HZ Yang JZ	1999	World Journal of Gastroenterology1999，5，3：	13
2	Toxic effects of over-load copper chloride on primary cultured rat asrocytes显示文摘	Hu HL Wang XP Zhao YL	2012	Parkinsonism Relat Disord2012，18，：	1
3	The correlation between mono- cyte chemoattractant protein-1 and the arthritis of systemic lupus erythematosus among Chinese 显示文摘	Ye DQ Hu YS Li XP	2005	Arch Dermatol Res2005，296，8：	1
4	Effects of CYP2C19 genetic polymorphlsm on the pharmacokinetics and pharmacoctynamics of omeprazole in Chinese people显示文摘	HU XP XU JM HU YM	2007	J Clin Pharm Ther2007，32，5：	1
5	Reduction and fixation of the avulsion fracture of the tibial eminence using mi- ni-open technique 显示文摘	Lu XW Hu XP Jin C	2010	Knee Surg Sports Traumatol Arthrosc2010，18，11：	1
6	Reduction and fixation of the avulsion fracture of the tibial eminence using mini-open tech- nique显示文摘	LU XW HU XP JIN C	2010	Knee Surg Sports Traumatol Arthrosc2010，18，11：	1
7	Role of mesohepatectomy with or without transcatheter arterial chemoembolization for large centrally located hepatocellular carcinoma显示文摘	Chen XP Hu DY Zhang ZW		0，，03：	1
8	One-Stage Total or Subtotal Aortic Replacement显示文摘	Hu XP Chang Q Sun LZ	2006	The Annals of Thoracic Surgery2006，82，2：	1
9	Identification and determina- tion of the major triterpcncs in Rhizoma Alismatis by HPLC - e- vaporative light scattering detection and HPLC/clcctrospray ioni- zation - MS' 显示文摘	CHEN LL HU ZF DING XP	2013	J AOAC Int2013，96，2：	1
10	Soluble egg antigen from Schistosoma japonicum modulates the progressionof chronic progressive experimental autoimmune encephalomyelitis viaTh2-shift response显示文摘	Zheng XP Hu XQ Zhou GY	2008	J Neuroimmunol2008，194，：	1
11	Rhizoma Paridisethanol extractselectively inhibits the proliferation of HUVECs comparing toLovo cells and shows anti-angiogenesis effects in a mouse model显示文摘	Qian XP Zhu U Hu J	2012	Journal of Ethnopharmacology2012，143，1：	1
12	Pulmonary function for pectus excavatum at long-term follow-up显示文摘	Jiang XP Hu TZ Liu WY		0，，：	1
13	Plasma thrombomodulin,Fibrinogen,and activity of tissue factor as risk factors for acute cerebral infarction显示文摘	Zhang XP Hu Y Hong M	2007	Am J Clin Pathol2007，128，2：	1
14	Cytochrome P450 1A1 exon 7 polymorphism and susceptibility to lung cancer in the Chinese population: an updated meta-analysis and review 显示文摘	Wei XP Hu J	2015	Onco Targets Ther2015，8，：	1
15	Treatment of complex coarctation and coarctation with cardiac lesions using extra-anatomic aortic bypass显示文摘	Wang R Sun LZ Hu XP	2010	J Vasc Surg2010，51，6：	1
16	Effect of CGRP on proliferation induced by angiotensin 11 in vascular smooth muscle cells 显示文摘	Qin XP Ye F Hu CP et aI	2004	Eur J Pharmaco2004，488，：	1
17	Effect o f CGRP o n proliferation induced by angiotensinII in vascular smooth muscle cells显示文摘	Qin XP Ye F Hu CP		0，，1：	1
18	Expression analysis ofthe ndrg2gene in mouse embryonic and adult tissues显示文摘	Hu XL Liu XP Deng YC	2006	Cell Tissue Res2006，325，1：	1
19	Effects of CYP2C19 genetic polymorphism on the pharmacokinetics and pharmacodynamics of omeprazole in Chinese people显示文摘	Hu XP Xu JM Hu YM	2007	J Clin Pharm Ther2007，32，5：	1
20	Plasma thrombomodulin,fibrinogen,and activity of tissue factor as risk factors for acute cerebral infarction显示文摘	Zhang XP Hu Y Hong M	2007	Am J Clin Pathol2007，128，：	1

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