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| 1 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 2 | A review of heavy-duty legged robots显示文摘Heavy-duty legged robots have been regarded as one of the important developments in the field of legged robots because of their high payload-total mass ratio,terrain adaptability,and multitasking.The problems associated with the development and use of heavy-duty legged robots have motivated researchers to conduct many important studies,covering topics related to the mechanical structure,force distribution,control strategy,energy efficiency,etc.Overall,heavy-duty legged robots have three main characteristics:greater body masses,larger body sizes,and higher payload-total mass ratios.Thus,various heavy-duty legged robots and their performances are reviewed here.This review presents the current developments with regard to heavy-duty legged robots.Also,the main characteristics of high-performance heavy-duty legged robots are determined and conclusions are drawn.Furthermore,the current research of key techniques of heavy-duty legged robots,including the mechanical structure,force distribution,control method,and power source,is described.To assess the transportation capacity of heavy-duty legged robots,performance evaluation parameters are proposed.Finally,problems that need further research are addressed. | ZHUANG HongChao GAO HaiBo DENG ZongQuan DING Liang LIU Zhen | 2014 | Science China(Technological Sciences)2014，57，2： | 15 |
| 3 | nterferon alpha (IFNα)-induced TRIM22 interrupts HCV 'eplication by ubiquitinating NS5A显示文摘 | Chen Yang Xinhao Zhao Dakang Sun Leilei Yang Chang Chong Yu Pan Xiumei Chi Yanhang Gao Moli Wang Xiaodong Shi Haibo Sun Juan Lv Yuanda Gao Jin Zhong Junqi Niu Bing Sun | 2016 | Cellular & Molecular Immunology2016，13，1： | 13 |
| 4 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
| 5 | Discovery of Triassic volcanic-sedimentary strata in the basement of Songliao Basin显示文摘In the Songliao Basin, the existence of lower Mesozoic strata remains a debatable issue. Previous studies indicated the absence of Triassic to Lower and Middle Jurassic strata in northeastern China because of uplift and erosion events associated with the return of geo-synclinal folds and orogenic movement during the Late Permian-Early Jurassic. To date, geochronological studies of intrusive and metamorphic rocks in the basement of the Songliao Basin have also confirmed Carboniferous, Permian, and Late Jurassic ages for the basement formations in general [1-4]. In the International Continental Scientific Drilling Project (ICDP) in the Songliao Basin, radiometric dating has been carried out for the entire drilling core of the SK-2 east borehole. As a result, we have discovered Triassic volcanic-sedimentary strata in the basement of the Songliao Basin. | Yongkang Yin Youfeng Gao Pujun Wang Xuejiao Qu Haibo Liu | 2019 | Science Bulletin2019，64，10： | 11 |
| 6 | Method for Analyzing Articulated Torques of Heavy-duty Six-legged Robot显示文摘The accuracy of an articulated torque analysis influences the comprehensive performances of heavy-duty multi-legged robots. Currently, the extremal estimation method and some complex methods are employed to calculate the articulated torques, which results in a large safety margin or a large number of calculations. To quickly obtain accurate articulated torques, an analysis method for the articulated torque is presented for an electrically driven heavy-duty six-legged robot. First, the rearmost leg that experiences the maximum normal contact force is confirmed when the robot transits a slope. Based on the ant-type and crab-type tripod gaits, the formulas of classical mechanics and MATLAB software are employed to theoretically analyze the relevant static torques of the joints. With the changes in the joint angles for the abductor joint, hip joint, and knee joint, variable tendency charts and extreme curves are obtained for the static articulated torques. Meanwhile, the maximum static articulated torques and the corresponding poses of the robot are also obtained. According to the poses of the robot under the maximum static articulated torques, ADAMS software is used to carry out a static simulation analysis. Based on the relevant simulation curves of the articulated torques, the maximum static articulated torques are acquired. A comparative analysis of the maximum static articulated torques shows that the theoretical calculation values are higher than the static simulation values, and the maximum error value is approximately 10%. The proposed method lays a foundation for quickly determining accurate articulated torques to develop heavy-duty six-legged robots. | ZHUANG Hongchao GAO Haibo DING Liang LIU Zhen DENG Zongquan | 2013 | Chinese Journal of Mechanical Engineering2013，26，4： | 9 |
| 7 | Feasibility and advantage of biofilm-electrode reactor for phenol degradation显示文摘The new biofilm-electrode method was used for the phenol degradation,because of its low current requirement.The biofilm-electrode reactor consisted of immobilized degrading bacteria on Ti electrode as cathode and Ti/PbO2 electrode as anode.With the biofilmelectrode reactor in a divided electrolytic cell,the phenol degradation rate could achieve 100%at 18 h which was higher than using traditional methods,such as biological or electrochemical methods.Chemical oxygen demand(COD)removal rate of the biofilmelectrode reactor was also greater than that using biological and electrochemical method,and could reach 80%at 16 h.The results suggested that the biofilm-electrode reactor system can be used to treat wastewater with phenol. | ZHANG Xuena HUANG Weimin WANG Xuan GAO Yu LIN Haibo | 2009 | Journal of Environmental Sciences2009，21，9： | 8 |
| 8 | A potential strategy for treating atherosclerosis: improving endothelial function via AMP-activated protein kinase显示文摘Endothelial dysfunction is caused by many factors, such as dyslipidemia, endoplasmic reticulum(ER) stress, and inflammation.It has been demonstrated that endothelial dysfunction is the initial process of atherosclerosis. AMP-activated protein kinase(AMPK) is an important metabolic switch that plays a crucial role in lipid metabolism and inflammation. However, recent evidence indicates that AMPK could be a target for atherosclerosis by improving endothelial function. For instance, activation of AMPK inhibits the production of reactive oxygen species induced by mitochondrial dysfunction, ER stress, and NADPH oxidase. Moreover, activation of AMPK inhibits the production of pro-inflammatory factors induced by dyslipidemia and hyperglycemia and restrains production of perivascular adipose tissue-released adipokines. AMPK activation prevents endothelial dysfunction by increasing the bioavailability of nitric oxide. Therefore, we focused on the primary risk factors involved in endothelial dysfunction, and summarize the features of AMPK in the protection of endothelial function, by providing signaling pathways thought to be important in the pathological progress of risk factors. | Feng Gao Jiemei Chen Haibo Zhu | 2018 | Science China(Life Sciences)2018，61，9： | 8 |
| 9 | Direct laser writing of volumetric gradient index lenses and waveguides显示文摘Direct laser writing(DLW)has been shown to render 3D polymeric optical components,including lenses,beam expanders,and mirrors,with submicrometer precision.However,these printed structures are limited to the refractive index and dispersive properties of the photopolymer.Here,we present the subsurface controllable refractive index via beam exposure(SCRIBE)method,a lithographic approach that enables the tuning of the refractive index over a range of greater than 0.3 by performing DLW inside photoresist-filled nanoporous silicon and silica scaffolds.Adjusting the laser exposure during printing enables 3D submicron control of the polymer infilling and thus the refractive index and chromatic dispersion.Combining SCRIBE’s unprecedented index range and 3D writing accuracy has realized the world’s smallest(15μm diameter)spherical Luneburg lens operating at visible wavelengths.SCRIBE’s ability to tune the chromatic dispersion alongside the refractive index was leveraged to render achromatic doublets in a single printing step,eliminating the need for multiple photoresins and writing sequences.SCRIBE also has the potential to form multicomponent optics by cascading optical elements within a scaffold.As a demonstration,stacked focusing structures that generate photonic nanojets were fabricated inside porous silicon.Finally,an all-pass ring resonator was coupled to a subsurface 3D waveguide.The measured quality factor of 4600 at 1550 nm suggests the possibility of compact photonic systems with optical interconnects that traverse multiple planes.SCRIBE is uniquely suited for constructing such photonic integrated circuits due to its ability to integrate multiple optical components,including lenses and waveguides,without additional printed supports. | Christian R.Ocier Corey A.Richards Daniel A.Bacon-Brown Qing Ding Raman Kumar Tanner J.Garcia Jorik van de Groep Jung-Hwan Song Austin J.Cyphersmith Andrew Rhode Andrea N.Perry Alexander J.Littlefield Jinlong Zhu Dajie Xie Haibo Gao Jonah F.Messinger Mark L.Brongersma Kimani C.Toussaint Jr Lynford L.Goddard Paul V.Braun | 2020 | Light(Science & Applications)2020，9，1： | 6 |
| 10 | Virtual Simulation System with Path-following Control for Lunar Rovers Moving on Rough Terrain显示文摘Virtual simulation technology is of great importance for the teleoperation of lunar rovers during the exploration phase,as well as the design of locomotion systems,performance evaluation,and control strategy verification during the R&D phase.The currently used simulation methods for lunar rovers have several disadvantages such as poor fidelity for wheel-soil interaction mechanics,difficulty in simulating rough terrains,and high complexity making it difficult to realize mobility control in simulation systems.This paper presents an approach for the construction of a virtual simulation system that integrates the features of 3D modeling,wheel-soil interaction mechanics,dynamics analysis,mobility control,and visualization for lunar rovers.Wheel-soil interaction experiments are carried out to test the forces and moments acted on a lunar rover’s wheel by the soil with a vertical load of 80 N and slip ratios of 0,0.03,0.05,0.1,0.2,0.3,0.4,and 0.6.The experimental results are referenced in order to set the parameters’ values for the PAC2002 tire model of the ADAMS/Tire module.In addition,the rough lunar terrain is simulated with 3DS Max software after analyzing its characteristics,and a data-transfer program is developed with Matlab to simulate the 3D reappearance of a lunar environment in ADAMS.The 3D model of a lunar rover is developed by using Pro/E software and is then imported into ADAMS.Finally,a virtual simulation system for lunar rovers is developed.A path-following control strategy based on slip compensation for a six-wheeled lunar rover prototype is researched.The controller is implemented by using Matlab/Simulink to carry out joint simulations with ADAMS.The designed virtual lunar rover could follow the planned path on a rough terrain.This paper can also provide a reference scheme for virtual simulation and performance analysis of rovers moving on rough lunar terrains. | GAO Haibo DENG Zongquan DING Liang WANG Mengyu | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 5 |
| 11 | Sulfur evolution in chemical looping combustion of coal with MnFe_2O_4 oxygen carrier显示文摘Chemical looping combustion(CLC) of coal has gained increasing attention as a novel combustion technology for its advantages in CO2 capture. Sulfur evolution from coal causes great harm from either the CLC operational or environmental perspective. In this research, a combined MnFe2O4 oxygen carrier(OC) was synthesized and its reaction with a typical Chinese high sulfur coal, Liuzhi(LZ) bituminous coal, was performed in a thermogravimetric analyzer(TGA)-Fourier transform infrared(FT-IR) spectrometer. Evolution of sulfur species during reaction of LZ coal with MnFe2O4 OC was systematically investigated through experimental means combined with thermodynamic simulation. TGA-FTIR analysis of the LZ reaction with MnFe2O4 indicated MnFe2O4 exhibited the desired superior reactivity compared to the single reference oxides Mn3O4 or Fe2O3, and SO2 produced was mainly related to oxidization of H2S by MnFe2O4. Experimental analysis of the LZ coal reaction with MnFe2O4, including X-ray diffraction and X-ray photoelectron spectroscopy analysis, verified that the main reduced counterparts of MnFe2O4 were Fe3O4 and MnO, in good agreement with the related thermodynamic simulation. The obtained MnO was beneficial to stabilize the reduced MnFe2O4 and avoid serious sintering, although the oxygen in MnO was not fully utilized. Meanwhile, most sulfur present in LZ coal was converted to solid MnS during LZ reaction with MnFe2O4, which was further oxidized to MnSO4. Finally, the formation of both MnS and such manganese silicates as Mn2SiO4 and MnSiO3 should be addressed to ensure the full regeneration of the reduced MnFe2O4. | Baowen Wang Chuchang Gao Weishu Wang Haibo Zhao Chuguang Zheng | 2014 | Journal of Environmental Sciences2014，26，5： | 5 |
| 12 | Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics显示文摘Colorectal cancer(CRC), a malignant tumor worldwide consists of microsatellite instability(MSI) and stable(MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, single-cell RNA sequencing wasperformed to explore the role of SHP2 in all cell types of tumor microenvironment(TME) from murine MC38 xenografts. Intratumoral cells were found to be functionally heterogeneous and responded significantly to SHP099, a SHP2 allosteric inhibitor. The malignant evolution of tumor cells was remarkably arrested by SHP099. Mechanistically, STING-TBK1-IRF3-mediated type I interferon signaling was highly activated by SHP099 in infiltrated myeloid cells. Notably, CRC patients with MSS phenotype exhibited greater macrophage infiltration and more potent SHP2 phosphorylation in CD68;macrophages than MSI-high phenotypes, suggesting the potential role of macrophagic SHP2 in TME. Collectively,our data reveals a mechanism of innate immunosuppression mediated by SHP2, suggesting that SHP2 is a promising target for colon cancer immunotherapy. | Jian Gao Zhigui Wu Mingxia Zhao Rui Zhang Manru Li Dongdong Sun Haibo Cheng Xianjia Qi Yuxian Shen Qiang Xu Hongqi Chen Dijun Chen Yang Sun | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 5 |
| 13 | KOH Direct Activation for Preparing Activated Carbon Fiber from Polyacrylonitrile-based Pre-oxidized Fiber显示文摘 | GAO Lili LU Haiyan LIN Haibo SUN Xiuyun XU Jianling LIU Dechen LI Yang | 2014 | Chemical Research in Chinese Universities2014，30，3： | 4 |
| 14 | PtNi-W/C with Atomically Dispersed Tungsten Sites Toward Boosted ORR in Proton Exchange Membrane Fuel Cell Devices显示文摘The performance of proton exchange membrane fuel cells is heavily dependent on the microstructure of electrode catalyst especially at low catalyst loadings.This work shows a hybrid electrocatalyst consisting of PtNi-W alloy nanocrystals loaded on carbon surface with atomically dispersed W sites by a two-step straightforward method.Single-atomic W can be found on the carbon surface,which can form protonic acid sites and establish an extended proton transport network at the catalyst surface.When implemented in membrane electrode assembly as cathode at ultra-low loading of 0.05 mgPt cm^(−2),the peak power density of the cell is enhanced by 64.4%compared to that with the commercial Pt/C catalyst.The theoretical calculation suggests that the single-atomic W possesses a favorable energetics toward the formation of*OOH whereby the intermediates can be efficiently converted and further reduced to water,revealing a interfacial cascade catalysis facilitated by the single-atomic W.This work highlights a novel functional hybrid electrocatalyst design from the atomic level that enables to solve the bottle-neck issues at device level. | Huawei Wang Jialong Gao Changli Chen Wei Zhao Zihou Zhang Dong Li Ying Chen Chenyue Wang Cheng Zhu Xiaoxing Ke Jiajing Pei Juncai Dong Qi Chen Haibo Jin Maorong Chai Yujing Li | 2023 | Nano-Micro Letters2023，15，9： | 3 |
| 15 | Three-layer intelligence of planetary exploration wheeled mobile robots:Robint,virtint,and humint显示文摘The great success of the Sojourner rover in the Mars Pathfinder mission set off a global upsurge of planetary exploration with autonomous wheeled mobile robots(WMRs),or rovers.Planetary WMRs are among the most intelligent space systems that combine robotic intelligence(robint),virtual intelligence(virtint),and human intelligence(humint) synergetically.This article extends the architecture of the three-layer intelligence stemming from successful Mars rovers and related technologies in order to support the R&D of future tele-operated robotic systems.Double-layer human-machine interfaces are suggested to support the integration of humint from scientists and engineers through supervisory(Mars rovers) or three-dimensional(3D) predictive direct tele-operation(lunar rovers).The concept of multilevel autonomy to realize robint,in particular,the Coupled-Layer Architecture for Robotic Autonomy developed for Mars rovers,is introduced.The challenging issues of intelligent perception(proprioception and exteroception),navigation,and motion control of rovers are discussed,where the terrains' mechanical properties and wheel-terrain interaction mechanics are considered to be key.Double-level virtual simulation architecture to realize virtint is proposed.Key technologies of virtint are summarized:virtual planetary terrain modeling,virtual intelligent rover,and wheel-terrain interaction mechanics.This generalized three-layer intelligence framework is also applicable to other systems that require human intervention,such as space robotic arms,robonauts,unmanned deep-sea vehicles,and rescue robots,particularly when there is considerable time delay. | DING Liang GAO HaiBo DENG ZongQuan LI YuanKai LIU GuangJun YANG HuaiGuang YU HaiTao | 2015 | Science China(Technological Sciences)2015，58，8： | 3 |
| 16 | Electrosorption behavior of cations with carbon nanotubes and carbon nanofibres composite film electrodes显示文摘 | Yang Gao Likun Pan HaiBo Li Yanping Zhang Zhejuan Zhang Yiwei Chen Zhuo Sun | 2008 | Thin Solid Films2008，，5： | 2 |
| 17 | Photonic engineering of superbroadband near-infrared emission in nanoglass composites containing hybrid metal and dielectric nanocrystals显示文摘Photonic media containing hybrid noble metal-dielectric nanocrystals(NCs)represent a wonderland of nanophotonics,with a myriad of uncharted optical functions yet to be explored.Capitalizing on the unique phase separation and spontaneous formation of Au-metal NCs in a gallosilicate glass,we fabricated Ni^2+-doped transparent nanoglass composites(GCs)containing Au-metal/γ-Ga2O3-dielectric NCs.Compared with GCs free of Au-metal NCs,the super broadband near-infrared emission of Ni^2+with a full width at half-maximum over280 nm is enhanced twice in the Au-metal/γ-Ga2O3 dual-phase GCs.A comparison is given as to the spontaneous emission(SPE)properties of Ni^2+in the dual-phase GCs when pumped resonantly and off-resonantly with the localized surface plasmon resonance band of the Au-metal NCs.The important role of the Au-metal NCs in the SPE enhancement is revealed by theoretical simulation based on the finite-element method.Combining the photonic engineering effect of hybrid Au-metal/γ-Ga2O3 NCs and the sensitization effect of Yb^3+on Ni^2+,a record-high enhancement factor of over 10 of the Ni^2+NIR emission is achieved,and optical gain is demonstrated in the GCs at the fiber communication wavelength. | ZHIGANG GAO HAIBO ZHU BOCHAO SUN YINGKE JI XIAOSONG LU HAO TIAN JING REN SHU GUO JIANZHONG ZHANG JUN YANG XIANGENG MENG KATSUHISA TANAKA | 2020 | Photonics Research2020，8，5： | 2 |
| 18 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | 2013 (9881)2013，，9881： | 2 |
| 19 | Involvement of the crebellum in sequential finger movement learning:Evidence from functional magnetic resonance imaging显示文摘Whether the cerebellum is involved in volun-tary motor learning or motor performance is the subject of a new debate. Using functional magnetic resonance imaging (fMRI), we examined cerebellar activation in eight volun-teers before and after an extended period of training. Activa-tion volume on both sides of cerebellum after learning was significantly reduced compared to that before learning even under the same motor frequency. Remarkably, while motor frequency for the training sequence was significantly higher than the control sequence after 41 d of learning, activation in the cerebellum for both sequences, with respect to activation loci and volumes, was very similar. These results suggest that the cerebellum was involved in motor learning but not motor performance. Changes of cerebellar activation from training thus appear to be associated with learning but not with im-provement on task performance. | ZHU Yihong DI Haibo YUAN Yi REN Jin'ge YU Wei ZHANG Zhaoqi GAO Jiahong WENG Xuchu CHEN Yizhang | 2005 | Chinese Science Bulletin2005，50，17： | 2 |
| 20 | Generation of transgenic golden Syrian hamsters显示文摘 | Mingming Gao Baoyu Zhang Jinjiao Liu Xin Guo Haibo Li Tao Wang Zifu Zhang Jiawei Liao Nathan Cong Yuhui Wang Liqing Dong Zhao George Liu | 2014 | Cell Research2014，24，3： | 2 |
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