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| 1 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 2 | Theoretical analysis on water-inrush mechanism of concealed collapse pillars in floor显示文摘以便从机械看法学习隐藏的倒塌支柱的水流入机制,为倒塌支柱的水流入的一个机械模型在这份报纸基于有弹性的力学的厚板理论被建立了。在水压力和批评的水压力的表示的行动下面由解决这为抗水的岩石阶层的变丑建模因为倒塌支柱水流入被获得了研究结果显示那:抗水的阶层的边界条件和力量在影响倒塌支柱的水流入起重要作用。批评水流入压力被相对厚度和抗水的阶层的绝对厚度决定。 | Tang Junhua Bai Haibo Yao Banghua WU YU | 2011 | Mining Science and Technology2011，21，1： | 12 |
| 3 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 4 | Numerical simulation on the risk of roof water inrush in Wuyang Coal Mine显示文摘Water-inrush in mine is one of the mine disasters caused by mining.In order to assess the risk of roof water-inrush in Wuyang Coal Mine based on the geological material of the coal mine,we built numerical models for the roof fracture and seepage development rule by using RFPA2D and COMSOL respectively,to analyze the changes in fracture zone,stress,water pressure and seepage vector with the advancement of working face,and compared the results with the field investigated data.The numerical simulation results indicate that:(1) with the advancement of the working faces,the stress relief range and fracture zone in the overlying strata increased rapidly up to about 90 m,and then tended to remain constant,reaching a final height of about 95 m which agrees with the field investigation;(2) the seepage flow constantly increased with a larger flow volume both in the front and rear area,where the stress concentration are the most serious. | Yao Banghua Bai Haibo Zhang Boyang | 2012 | International Journal of Mining Science and Technology2012，22，2： | 11 |
| 5 | Water protection in the western semiarid coal mining regions of China: A case study显示文摘The coal industry in China has been moving from the semiarid eastern to the drier western regions since the beginning of this century.Water protection is of the utmost concern for coal mining in these regions.Lu'an,as one of the state coal mining bases in China,has been seeing increasingly heavier pressure for the protection of water resources.This article considers Lu'an as an example and describes the ways these concerns may be alleviated.High mine-water utilization rates have effectively reduced wasting of water and,consequently,have reduced water demand.Using the top layers of the Ordavician as aquifuge barriers can prevent floor karst water inrush into the longwall face and can protect the regional Ordovician karst water resources at the same time.The strength of the overlying Quaternary clay can protect against roof collapse and has successfully preserved the Quaternary porous water resource. | Huang Hanfu Wang Changshen Bai Haibo Wang Zihe | 2012 | International Journal of Mining Science and Technology2012，22，5： | 5 |
| 6 | A state‑of‑the‑art review on rock seepage mechanism of water inrush disaster in coal mines显示文摘Water inrush is one of the most dangerous disasters in coal mining.Due to the large-scale mining and complicated hydrogeological conditions,thousands of deaths and huge economic losses have been caused by water inrush disasters in China.There are two main factors determining the occurrence of water inrush:water source and water-conducting pathway.Research on the formation mechanism of the water-conducting pathway is the main direction to prevent and control the water inrush,and the seepage mechanism of rock mass during the formation of the water-conducting pathway is the key for the research on the water inrush mechanism.This paper provides a state-of-the-art review of seepage mechanisms during water inrush from three aspects,i.e.,mechanisms of stress-seepage coupling,fow regime transformation and rock erosion.Through numerical methods and experimental analysis,the evolution law of stress and seepage felds in the process of water inrush is fully studied;the fuid movement characteristics under diferent fow regimes are clearly summarized;the law of particle initiation and migration in the process of water inrush is explored,and the efect of rock erosion on hydraulic and mechanical properties of the rock media is also studied.Finally,some limitations of current research are analyzed,and the suggestions for future research on water inrush are proposed in this review. | Dan Ma Hongyu Duan Jixiong Zhang Haibo Bai | 2022 | International Journal of Coal Science & Technology2022，9，4： | 4 |
| 7 | Pore structure characteristics of the relative water-resisting layer on the top of the Ordovician in Longgu Coal Mine显示文摘In order to study the permeability and water-resisting ability of the strata on the top of the Ordovician in Longgu Coal Mine, this paper tested the permeability and porosity of the strata, investigated the fracture and pore structure features of the strata, and identified the main channels which govern the permeability and water-resisting ability of the strata. The permeability of the upper, central and lower strata shows as2.0504 ·10à3–2.782762 · 10à3, 4.1092 ·10à3–7.3387·10à3and 2.0891·10à3–3.2705 ·10à3lm2,respectively, and porosity of that is 0.6786–0.9197%, 0.3109–0.3951% and 0.9829–1.8655%, respectively.The results indicate that:(1) the main channels of the relative water-resisting layer are the pore throats with a diameter more than 6 lm;(2) the major proportion of pore throats in the vertical flow channel and the permeability first increases and then sharply decreases;(3) the fractures occurring from the top to20 m in depth of the strata were filled and there occurred almost no fracture under the depth of 40 m;and(4) the ratio of turning point of the main flow channel in the strata on top of Ordovician can be used to confirm the thickness of filled water-resisting layers. | Rong Huren Bai Haibo | 2014 | International Journal of Mining Science and Technology2014，24，5： | 3 |
| 8 | Seepage characteristics of collapse column fillings显示文摘With concealment and hysteresis,water-inrush from Karst collapse column has become an important security hazard of lower group coal mining in North China.Based on the MTS8 15.02 seepage test system,we analyzed the impact of consolidation pressure,initial moisture content and confining pressure on the permeability of fillings in order to study the seepage characteristics of collapse column fillings.The results show that:(l)The permeability of collapse column fillings is of the order of 10^(-16)-10^(-15) magnitude and decreases with an increase in consolidation pressure and decrease in initial moisture content.(2) The essence of filling seepage law change is the change in porosity,and a power function relationship exists between the permeability ratio and porosity ratio.(3) With increasing confining pressure,the permeability of fillings decreases.However,under low confining pressure(1.2-4 MPa),the change of confining pressure has no obvious influence on the permeability. | Zhang Boyang Bai Haibo Zhang Kai | 2016 | International Journal of Mining Science and Technology2016，26，2： | 2 |
| 9 | Mechanical behavior of groundwater seepage in Karst collapse pil- lars显示文摘 | BAI Haibo MA Dan CHEN Zhanqing | 2013 | Engineering Geology2013，164，： | 1 |
| 10 | Power law and multi-scaling properties of the Chinese stock market显示文摘 | Bai Manying Zhu Haibo | 2010 | Physica A: Statistical Mechanics and its Applications2010，389，9： | 1 |
| 11 | Anengineering application about measuring water flowing fracture zones under a coal seam显示文摘 | YANG Cheng BAI Haibo LI Hailong | 2013 | The Electronic Journal of Geotechnical Engineering2013，18，1： | 1 |
| 12 | An establishment about the floor strata strengthened by grouting system显示文摘 | YANG Cheng BAI Haibo JIAO Yang | 2013 | The Electronic Journal of Geotech- nicalEngineering2013，18，5： | 1 |
| 13 | Two-Dimensional Pnictogen for Field-Effect Transistors显示文摘Two-dimensional(2D)layered materials hold great promise for various future electronic and optoelectronic devices that traditional semiconductors cannot afford.2D pnictogen,group-VA atomic sheet(including phosphorene,arsenene,antimonene,and bismuthene)is believed to be a competitive candidate for next-generation logic devices.This is due to their intriguing physical and chemical properties,such as tunable midrange bandgap and controllable stability.Since the first black phosphorus fieldeffect transistor(FET)demo in 2014,there has been abundant exciting research advancement on the fundamental properties,preparation methods,and related electronic applications of 2D pnictogen.Herein,we review the recent progress in both material and device aspects of 2D pnictogen FETs.This includes a brief survey on the crystal structure,electronic properties and synthesis,or growth experiments.With more device orientation,this review emphasizes experimental fabrication,performance enhancing approaches,and configuration engineering of 2D pnictogen FETs.At the end,this review outlines current challenges and prospects for 2D pnictogen FETs as a potential platform for novel nanoelectronics. | Wenhan Zhou Jiayi Chen Pengxiang Bai Shiying Guo Shengli Zhang Xiufeng Song Li Tao Haibo Zeng | 2019 | Research2019，，1： | 1 |
| 14 | Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation显示文摘One major strategy to generate genetically modified mouse models is gene targeting in mouse embryonic stem(ES)cells,which is used to produce gene-targeted mice for wide applications in biomedicine.However,a major bottleneck in this approach is that the robustness of germiine transmission of gene-targeted ES cells can be significantly reduced by their genetic and epigenetic instability after long-term culturing,which impairs the efficiency and robustness of mouse model generation.Recently,we have established a new type of pluripotent cells termed extended pluripotent stem(EPS)cells,which have superior developmental potency and robust germline competence compared to conventional mouse ES cells.In this study,we demonstrate that mouse EPS cells well maintain developmental potency and genetic stability after long-term passage.Based on gene targeting in mouse EPS cells,we established a new approach to directly and rapidly generate gene-targeted mouse models through tetraploid complementation,Haibo Li and Chaoran Zhao contributed equally to this work.Electronic supplementary material The online version of this article(http://gffzzd3cc09b8251d45dfs0c6vcqqvx0ff6k0u.ffgz.tsg.suse.edu.cn/10.1007/s13238-018-0556-1)contains supplementary material,which is available to authorized users.which could be accomplished in approximately 2 months.Importantly,using this approach,we successfully constructed mouse models in which the human interleukin 3(IL3)or interleukin 6(IL6)gene was knocked into its corresponding locus in the mouse genome.Our study demonstrates the feasibility of using mouse EPS cells to rapidly generate mouse models by gene targeting,which have great application potential in biomedical research. | Haibo Li Chaoran Zhao Jun Xu Yaxing Xu Chunmei Cheng Yinan Liu Ting Wang Yaqin Du Liangfu Xie Jingru Zhao Yanchuang Han Xiaobao Wang Yun Bai Hongkui Deng | 2019 | Protein & Cell2019，10，1： | 1 |
| 15 | The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals显示文摘 | Nailing Zhang Haibo Bai Karen K. David Jixin Dong Yonggang Zheng Jing Cai Marco Giovannini Pentao Liu Robert A. Anders Duojia Pan | 2010 | Developmental Cell2010，，1： | 1 |
| 16 | A Preliminary Report of Penile Transplantation显示文摘 | Weilie Hu Jun Lu Lichao Zhang Wen Wu Haibo Nie Yunsong Zhu Zhixiong Deng Yongbing Zhao Wen Sheng Qiyou Chao Xiaofu Qiu Jinghua Yang Ying Bai | 2006 | European Urology2006，，4： | 1 |
| 17 | The DELLA-ABI4-HY5 module integrates light and gibberellin signals to regulate hypocotyl elongation显示文摘Plant growth is coordinately controlled by various environmental and hormonal signals,of which light and gibberellin(GA)signals are two critical factors with opposite effects on hypocotyl elongation.Although interactions between the light and GA signaling pathways have been studied extensively,the detailed regulatory mechanism of their direct crosstalk in hypocotyl elongation remains to be fully clarified.Previously,we reported that ABA INSENSITIVE 4(ABI4)controls hypocotyl elongation through its regulation of cellelongation-related genes,but whether it is also involved in GA signaling to promote hypocotyl elongation is unknown.In this study,we showthat promotion of hypocotyl elongation by GA is dependent on ABI4 activation.DELLAs interact directly with ABI4 and inhibit its DNA-binding activity.In turn,ABI4 combined with ELONGATED HYPOCOTYL 5(HY5),a key positive factor in light signaling,feedback regulates the expression of the GA2ox GA catabolism genes and thus modulates GA levels.Taken together,our results suggest that the DELLA-ABI4-HY5 module may serve as a molecular link that integrates GA and light signals to control hypocotyl elongation. | Haibo Xiong Dandan Lu Zhiyuan Li Jianghao Wu Xin Ning Weijun Lin Zechen Bai Canhui Zheng Yang Sun Wei Chi Lixin Zhang Xiumei Xu | 2023 | Plant Communications2023，4，5： | 0 |
| 18 | The Calculation of Heating Radius and Determination of Parameters in Heavy Oil Steam Stimulation显示文摘在稠油吞吐过程中,加热半径是热采中的重要指标,对注汽参数和生产制度起到了指导性作用。运用能量守恒原理,从热量注入方面考虑了蒸汽相变释放的气化潜热,从热量损失方面考虑井筒热量损失和顶底盖层热量损失,最终得到了新的加热半径计算公式。计算结果表明,加热半径受注汽参数、焖井时间、储层参数等因素影响,并系统阐述了岩层各物性参数的计算及选择方法。最后通过实例验证了该方法的计算值和试井解释出的值较为相符,为现场实际应用提供了可靠的方法。 | Aiping Zheng Xiujuan Bai Yushu Zhang Haibo Cao Jiaen Lin | 2017 | 石油天然气学报2017，39，3： | 0 |
| 19 | Electronic band structures and optical properties of atomically thin AuSe: first-principle calculations显示文摘As a large family of 2D materials, transition metal dichalcogenides(TMDs) have stimulated numerous works owing to their attractive properties. The replacement of constituent elements could promote the discovery and fabrication of new nanofilm in this family. Using precious metals, such as platinum and palladium, to serve as transition metals combined with chalcogen is a new approach to explore novel TMDs. Also, the proportion between transition metal and chalcogen atoms is found not only to exist in conventional form of 1 : 2. Herein, we reported a comprehensive study of a new 2D precious metal selenide, namely AuSe monolayer. Based on density functional theory, our result indicated that AuSe monolayer is a semiconductor with indirect band-gap of 2.0 eV, which possesses superior dynamic stability and thermodynamic stability with cohesive energy up to–7.87 eV/atom. Moreover, it has been confirmed that ionic bonding predominates in Au–Se bonds and absorption peaks in all directions distribute in the deep ultraviolet region. In addition, both vibration modes dominating marked Raman peaks are parallel to the 2D plane. | Pengxiang Bai Shiying Guo Shengli Zhang Hengze Qu Wenhan Zhou Haibo Zeng | 2019 | Journal of Semiconductors2019，40，6： | 0 |
| 20 | Clinical significance of serum IgM and IgG levels in COVID-19 patients in Hubei Province,China显示文摘Background:There have been many studies about coronavirus disease 2019(COVID-19),but the clinical signifi-cance of quantitative serum severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2)-specific IgM and IgG levels of COVID-19 patients have not been exhaustively analyzed.We aimed to investigate the time profiles of these IgM/IgG levels in COVID-19 patients and their correlations with clinical features.Methods:A multicenter clinical study was conducted from February 20 to March 52020.It involved 179 COVID-19 patients(108 males and 71 females)from five hospitals in Huangshi in Hubei Province,China.To detect SARS-CoV-2-specific IgM/IgG,quantitative antibody assays(two-step indirect immunoassays with direct chemilu-minescence technology)based on the nucleocapsid protein(NP)and spike protein 1(S1)were used.For normally distributed data,means were compared using the t-test,��2-test,or exact probability method.For categorical data,medians were compared using Mann-Whitney U test.Results:The median age was 57(44-69)years(58[38-69]for males and 57[49-68]for females).The median duration of positive nucleic acid test was 22.32(17.34-27.43)days.The mortality rate was relatively low(3/179,1.68%).Serum SARS-CoV-2-specific IgG was detected around week 1 after illness onset,gradually increased until peaking in weeks 4 and 5,and then declined.Serum IgM peaked in weeks 2 and 3,then gradually declined and returned to its normal range by week 7 in all patients.Notably,children had milder respiratory symptoms with lower SARS-CoV-2-specific IgM/IgG levels.The duration of positive nucleic acid test in the chronic obstructive pulmonary disease(COPD)group was 30.36(18.99-34.76)days,which was significantly longer than that in the non-COPD group(21.52[16.75-26.51]days;P=0.025).The peak serum SARS-CoV-2-specific IgG was sig-nificantly positively correlated with the duration of positive nucleic acid test.The incidence rate of severe and critical cases in the IgM hi group(using the median IgM level of 29.95 AU/mL as the cutofffor grouping)was about 38.0%(19/50),which was twice as much as that in the IgM lo group(18.4%;9/49).The patients with positive chest imaging and lymphocytopenia(<1×10^(9)/L)had a higher SARS-CoV-2-specific IgM level.Conclusions: Quantitative SARS-CoV-2-specific IgM and IgG levels are helpful for the diagnosis, severity classifi- cation, and management of COVID-19 patients, and they should be monitored in each stage of this disease. | Zhenjiang Bai Qing Li Qinghui Chen Changming Niu Yu Wei Hanpeng Huang Wei Zhao Nian Chen Xin Yao Qiang Zhang Chuanyong Mu Jian Feng Chuanlong Zhu Zhuo Li Ming Ding Binhui Feng Chaochao Jin Xiang Lu Yi Yang Shuiyan Wu Xiaochen Shu Haibo Qiu YingZi Huang | 2022 | Journal of Intensive Medicine2022，2，1： | 0 |
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