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| 1 | New incompatible pair of TCM:Epimedii Folium combined with Psoraleae Fructus induces idiosyncratic hepatotoxicity under immunological stress conditions显示文摘Epimedii Folium(EF)combined with Psoraleae Fructus(PF)is a common modern preparation,but liver injury caused by Chinese patent medicine preparations containing EF and PF has been frequently reported in recent years.Zhuangguguanjiewan pills(ZGW),which contain EF and PF,could induce immune idiosyncratic liver injury according to clinical case reports and a nonhepatotoxic dose of lipopolysaccharide(LPS)model.This present study evaluated the liver injury induced by EF or PF alone or in combination and investigated the related mechanism by using the LPS model.Liver function indexes and pathological results showed that either EF or PF alone or in combination led to liver injury in normal rats;however,EF or PF alone could lead to liver injury in LPS-treated rats.Moreover,EF combined with PF could induce a greater degree of injury than that caused by EF or PF alone in LPS-treated rats.Furthermore,EF or PF alone or in combination enhanced the LPS-stimulated inflammatory cytokine production,implying that IL-1β,which is processed and released by activating the NLRP3 inflammasome,is a specific indicator of EF-induced immune idiosyncratic hepatotoxicity.Thus,EF may induce liver injury through enhancing the LPS-mediated proinflammatory cytokine production and activating the NLRP3 inflammasome.In addition,the metabolomics analysis results showed that PF affected more metabolites in glycerophospholipid and sphingolipid metabolic pathways compared with EF in LPS model,suggesting that PF increased the responsiveness of the liver to LPS or other inflammatory mediators via modulation of multiple metabolic pathways.Therefore,EF and PF combination indicates traditional Chinese medicine incompatibility,considering that it induces idiosyncratic hepatotoxicity under immunological stress conditions. | Yuan Gao Zhilei Wang Jinfa Tang Xiaoyi Liu Wei Shi Nan Qin Xiaoyan Wang Yu Pang Ruisheng Li Yaming Zhang Jiabo Wang Ming Niu Zhaofang Bai Xiaohe Xiao | 2020 | Frontiers of Medicine2020，14，1： | 32 |
| 2 | Progress in Global Gas Hydrate Development and Production as a New Energy Resource显示文摘Natural gas hydrates have been hailed as a new and promising unconventional alternative energy,especially as fossil fuels approach depletion,energy consumption soars,and fossil fuel prices rise,owing to their extensive distribution,abundance,and high fuel efficiency.Gas hydrate reservoirs are similar to a storage cupboard in the global carbon cycle,containing most of the world's methane and accounting for a third of Earth's mobile organic carbon.We investigated gas hydrate stability zone burial depths from the viewpoint of conditions associated with stable existence of gas hydrates,such as temperature,pressure,and heat flow,based on related data collected by the global drilling programs.Hydrate-related areas are estimated using various biological,geochemical and geophysical tools.Based on a series of previous investigations,we cover the history and status of gas hydrate exploration in the USA,Japan,South Korea,India,Germany,the polar areas,and China.Then,we review the current techniques for hydrate exploration in a global scale.Additionally,we briefly review existing techniques for recovering methane from gas hydrates,including thermal stimulation,depressurization,chemical injection,and CH4-CO2 exchange,as well as corresponding global field trials in Russia,Japan,United States,Canada and China.In particular,unlike diagenetic gas hydrates in coarse sandy sediments in Japan and gravel sediments in the United States and Canada,most gas hydrates in the northem South China Sea are non-diagenetic and exist in fine-grained sediments with a vein-like morphology.Therefore,especially in terms of the offshore production test in gas hydrate reservoirs in the Shenhu area in the north slope of the South China Sea,Chinese scientists have proposed two unprecedented techniques that have been verified during the field trials:solid fluidization and formation fluid extraction.Herein,we introduce the two production techniques,as well as the so-called'fbur-in-one'environmental monitoring system employed during the Shenhu production test.Methane is not currently commercially produced from gas hydrates anywhere in the world;therefore,the objective of field trials is to prove whether existing techniques could be applied as feasible and economic production methods for gas hydrates in deep-water sediments and permafrost zones.Before achieving commercial methane recovery from gas hydrates,it should be necessary to measure the geologic properties of gas hydrate reservoirs to optimize and improve existing production techniques.Herein,we propose horizontal wells,multilateral wells,and cluster wells improved by the vertical and in dividual wells applied during existing field trials.It is noteworthy that relatively pure gas hydrates occur in seafloor mounds,within near-surface sediments,and in gas migration conduits.Their extensive distribution,high saturation,and easy access mean that these types of gas hydrate may attract considerable attention from academia and industry in the future.Herein,we also review the occurrence and development of concentrated shallow hydrate accumulations and briefly introduce exploration and production techniques.In the closing section,we discuss future research needs,key issues,and major challenges related to gas hydrate exploration and production.We believe this review article provides insight on past,present,and future gas hydrate exploration and production to provide guidelines and stimulate new work into the field of gas hydrates. | LIU Liping SUN Zhilei ZHANG Lei WU Nengyou Yichao Qin JIANG Zuzhou GENG Wei CAO Hong ZHANG Xilin ZHAI Bin XU Cuiling SHEN Zhicong JIA Yonggang | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 13 |
| 3 | Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity显示文摘Psoraleae Fructus(PF)is a well-known traditional herbal medicine in China,and it is widely used for osteoporosis,vitiligo,and other diseases in clinical settings.However,liver injury caused by PF and its preparations has been frequently reported in recent years.Our previous studies have demonstrated that PF could cause idiosyncratic drug-induced liver injury(IDILI),but the mechanism underlying its hepatotoxicity remains unclear.This paper reports that bavachin isolated from PF enhances the specific stimuli-induced activation of the NLRP3 inflammasome and leads to hepatotoxicity.Bavachin boosts the secretion of IL-ip and caspase-1 caused by ATP or nigericin but not those induced by poly(I:C),monosodium urate crystal,or intracellular lipopolysaccharide.Bavachin does not affect AIM2 or NLRC4 inflammasome activation.Mechanistically,bavachin specifically increases the production of nigericin-induced mitochondrial reactive oxygen species among the most important upstream events in the activation of the NLRP3 inflammasome.Bavachin increases the levels of aspartate transaminase and alanine aminotransferase in serum and hepatocyte injury accompanied by the secretion of IL-ip via a mouse model of lipopolysaccharide-mediated susceptibility to IDILI.These results suggest that bavachin specifically enhances the ATP-or nigericin-induced activation of the NLRP3 inflammasome.Bavachin also potentially contributes to PF-induced idiosyncratic hepatotoxicity.Moreover,bavachin and PF should be evaded among patients with diseases linked to the ATP-or nigericin-mediated activation of the NLRP3 inflammasome,which may be a dangerous factor for liver injury. | Nan Qin Guang Xu Yan Wang Xiaoyan Zhan Yuan Gao Zhilei Wang Shubin Fu Wei Shi Xiaorong Hou Chunyu Wang Ruisheng Li Yan Liu Jiabo Wang Haiping Zhao Xiaohe Xiao Zhaofang Bai | 2021 | Frontiers of Medicine2021，15，4： | 9 |
| 4 | Characteristics of pantograph‐catenary arc under low air pressure and strong airflow显示文摘Pantograph‐catenary arc fault is the primary factor threatening the stability of the power transmission for high‐speed railway.The motion characteristics of the pantograph‐catenary arc under low air pressure and strong airflow is significantly different from the case under atmospheric pressure.In this paper,an experimental platform of panto-graph‐catenary arc was built to investigate arc root position‐time and arc column lon-gitudinal drift height‐time characteristic curves under different air pressures and airflow velocites.Via analysing the corresponding results,it can be found that there are different arc root-arc column traction mechanisms at different stages of arc development.The arcing time and arc root stagnation time under low air pressure are significantly longer than the case under atmospheric pressure,resulting in more serious electrode ablation.The arc column longitudinal drift velocity and height are greater with the increase of airflow velocity.Two typical irregular arc motion phenomena-arc root jumping and arc reignition are observed.To clarify the internal mechanism of the above phenomenon,a magnetohydrodynamics(MHD)model of the pantograph‐catenary arc was lauched,the influence mechanism of the pantograph‐catenary arc temperature and voltage are studied,and the physical process of arc temperature oscillation is analysed.The research results provide theoretical support for arc protection in high‐altitude areas. | Zhilei Xu Guoqiang Gao Wenfu Wei Zefeng Yang Wenhan Xie Keliang Dong Yaguang Ma Yan Yang Guangning Wu | 2022 | High Voltage2022，7，2： | 7 |
| 5 | Provenance of Central Canyon in Qiongdongnan Basin as evidenced by detrital zircon U-Pb study of Upper Miocene sandstones显示文摘Deep-water canyon systems can provide important sandstone reservoirs for deep-water oil and gas exploration in the South China Sea;however,the sedimentary provenance of the Central Canyon in the Qiongdongnan Basin remains controversial.In this work,detrital zircon grains from three drilling sandstones in the Upper Miocene Huangliu Formation in the western part of the Central Canyon were analysed by LA-ICP-MS for U-Pb ages,in order to constrain their provenance.One hundred and ninety-one zircon grains yield concordant U-Pb ages ranging from 28.6 to 3285 Ma.Most of them show oscillatory or linear zoning in CL-images and high Th/U ratios(>0.1),suggesting that they are magmatic zircons.Three major age clusters at about30 Ma(N=6),220–270 Ma(N=29),and 420–440 Ma(N=13),and five minor age clusters at 70–110 Ma(N=7),150–170 Ma(N=4),800–850 Ma(N=11),1800–2000 Ma(N=16),and 2400–2600 Ma(N=7),can be identified in the age spectrum,which are very similar to those of the Upper Miocene sandstones and modern river sands in the Red River area,but different from those of other nearby regions(e.g.,Hainan Island,the Pearl River area,and the Mekong River area)in Southeast Asia.The major age peak at about 30 Ma in our samples is consistent with the timing of tectonothermal events in the Red River Fault Zone.Therefore,we suggest that the provenance of the western part of the Central Canyon,in the Qiongdongnan Basin,was fed dominantly by the Paleo-Red River system during the Late Miocene. | CHEN Hui XIE XiNong GUO JingLiang SU Ming ZONG KeQing SHANG Fei HUANG Wei WANG Wei SHANG ZhiLei | 2015 | Science China Earth Sciences2015，58，8： | 6 |
| 6 | Phytochrome B interacts with SWC6 and ARP6 to regulate H2A.Z deposition and photomorphogensis in Arabidopsis显示文摘Light serves as a crucial environmental cue which modulates plant growth and development, and which is controlled by multiple photoreceptors including the primary red light photoreceptor,phytochrome B(phyB). The signaling mechanism of phyB involves direct interactions with a group of basic helix-loop-helix(bHLH) transcription factors, PHYTOCHROME-INTERACTING FACTORS(PIFs), and the negative regulators of photomorphogenesis, COP1 and SPAs. H2 A.Z is an evolutionarily conserved H2 A variant which plays essential roles in transcriptional regulation. The replacement of H2 A with H2 A.Z is catalyzed by the SWR1 complex. Here, we show that the Pfr form of phyB physically interacts with the SWR1 complex subunits SWC6 and ARP6. phyB and ARP6 coregulate numerous genes in the same direction,some of which are associated with auxin biosynthesis and response including YUC9, which encodes a rate-limiting enzyme in the tryptophandependent auxin biosynthesis pathway. Moreover,phyB and HY5/HYH act to inhibit hypocotyl elongation partially through repression of auxin biosynthesis. Based on our findings and previous studies, we propose that phyB promotes H2 A.Z deposition at YUC9 to inhibit its expression through direct phyB-SWC6/ARP6 interactions,leading to repression of auxin biosynthesis, and thus inhibition of hypocotyl elongation in red light. | Xuxu Wei Wanting Wang Peng Xu Wenxiu Wang Tongtong Guo Shuang Kou Minqing Liu Yake Niu Hong-Quan Yang Zhilei Mao | 2021 | Journal of Integrative Plant Biology2021，63，6： | 6 |
| 7 | Pantograph-catenary electrical contact system of high-speed railways:recent progress,challenges,and outlooks显示文摘As the unique power entrance,the pantograph-catenary electrical contact system maintains the efficiency and reliability of power transmission for the high-speed train.Along with the fast development of high-speed railways all over the world,some commercialized lines are built for covering the remote places under harsh environment,especially in China;these environmental elements including wind,sand,rain,thunder,ice and snow need to be considered during the design of the pantograph-catenary system.The pantograph-catenary system includes the pantograph,the contact wire and the interface—pantograph slide.As the key component,this pantograph slide plays a critical role in reliable power transmission under dynamic condition.The fundamental material characteristics of the pantograph slide and contact wire such as electrical conductivity,impact resistance,wear resistance,etc.,directly determine the sliding electrical contact performance of the pantograph-catenary system;meanwhile,different detection methods of the pantograph-catenary system are crucial for the reliability of service and maintenance.In addition,the challenges brought from extreme operational conditions are discussed,taking the Sichuan-Tibet Railway currently under construction as a special example with the high-altitude climate.The outlook for developing the ultra-high-speed train equipped with the novel pantograph-catenary system which can address the harsher operational environment is also involved.This paper has provided a comprehensive review of the high-speed railway pantograph-catenary systems,including its progress,challenges,outlooks in the history and future. | Guangning Wu Keliang Dong Zhilei Xu Song Xiao Wenfu Wei Huan Chen Jie Li Zhanglin Huang Jingwei Li Guoqiang Gao Guozheng Kang Chuanjun Tu Xingyi Huang | 2022 | Railway Engineering Science2022，30，4： | 5 |
| 8 | Rare-earth element geochemistry reveals the provenance of sediments on the southwestern margin of the Challenger Deep显示文摘The hadal zone represents one of the last great frontiers in modern marine science,and deciphering the provenance of sediment that is supplied to these trench settings remains a largely unanswered question.Here,we examine the mineralogical and geochemical composition of a sediment core(core CD-1)that was recovered from the southwestern margin of the Challenger Deep within the Mariana Trench.Major element abundances and rare-earth element patterns from these sediments require inputs from both terrigenous dust and locally sourced volcanic debris.We exploit a two-endmember mixing model to demonstrate that locally sourced volcanic material dominates the sediment supply to the Challenger Deep(averaging^72%).The remainder,however,is supplied by aeolian dust(averaging^28%),which is consistent with adjacent studies that utilized Sr-Nd isotopic data.Building on a growing database,we strengthen our understanding of Asian aeolian dust input into the northwestern Pacific,which ultimately improves our appreciation of sedimentation in,and around,the hadal zone. | JIANG Zuzhou SUN Zhilei LIU Zhaoqing CAO Hong GENG Wei XU Haixia WANG Lisheng WANG Libo | 2019 | Journal of Oceanology and Limnology2019，37，3： | 5 |
| 9 | Synthesis of nearly spherical AlN particles by an in-situ nitriding combustion route显示文摘Spherical AlN powders with micrometer size have attracted great attention owing to their good fluidity and dispersity. However, the industrial preparation methods usually require high temperature and long soaking time, which lead to the high cost and limit the wide application of the products. Herein, nearly spherical AlN particles with the average size of 2.5 μm were successfully synthesized via an in-situ combustion synthesis method. The effect of N_(2) pressure, NH_(4)Cl content, and Al particle size on the combustion reaction procedure, phase composition, and microstructure of the products was systematically investigated. The results showed that the decreased N_(2) pressure, increased NH_(4)Cl content, and Al particle size led to the decreasing of combustion temperature and speed, which further affected the morphology of the products. As a result, low N_(2) pressure(0.2 MPa), a small amount of NH4Cl(0.5 wt%), and fine Al particles(~2.5 μm) contributed to a moderate combustion temperature and facilitated the formation of nearly spherical AlN particles. In addition, based on the gas-releasing assisted quenching experiments and thermo-kinetic analysis, a two-step growth mechanism for the nearly spherical AlN particles was rationally proposed. The present method shows the advantages of low cost and high efficiency for preparing nearly spherical AlN particles, which can be used as raw materials for electronic substrates and fillers for packaging materials. | Zhilei Wei Kang Li Bangzhi Ge Chaowei Guo Hongyan Xia Yajie Guo Zhongqi Shi | 2021 | Journal of Advanced Ceramics2021，10，2： | 2 |
| 10 | Preparation of unidirectional porous AlN ceramics via the combination of freeze casting and combustion synthesis显示文摘Unidirectional porous AlN ceramics(UP-AlNs)have attracted great attention for their wide applications in catalyst supports,filters and composite reinforcements.However,traditional fabrication processes usually require high temperature and long production cycle.Herein,UP-AlNs were successfully fabricated via the combination of tertiary butyl alcohol(TBA)-based freeze casting and combustion synthesis route using Al and AlN powders as raw materials.The microstructure,open porosity,thermal conductivity and compressive strength of UP-AlNs can be manipulated by synergistically regulating the AlN diluent content and Al/AlN solid loading of the freezing slurries.The optimal UP-AlNs exhibited controllable structure wavelength(λ)and open porosity in a wide range of 21.1-47.1μm and 54.2%-86.0%,respectively.In addition,the corresponding products also possessed anisotropic thermal conductivity and compressive strength.This novel route for the fabrication of UP-AlNs has the advantages of low cost,energy-saving and high efficiency,which shows significant promise for industrial applications. | Zhilei Wei Zhejian Zhang Xiaoyu Zhang Zhiyuan Li Tao Li Jiabin Hu Shunjian Xu Zhongqi Shi | 2022 | Journal of Materials Science & Technology2022，，5： | 1 |
| 11 | Intravenous and nebulized magnesium sulfate for treating acute asthma in adults and children: A systematic review and meta-analysis显示文摘 | Zhilei Shan Ying Rong Wei Yang Di Wang Ping Yao Jungang Xie Liegang Liu | 2013 | Respiratory Medicine2013，，3： | 1 |
| 12 | Preparation of SiC coated graphite composite powders by nitriding combustion synthesis显示文摘Ceramic-coated graphite powders are considered as effective raw materials to fabricate three-dimensional continuous ceramic skeleton-reinforced graphite matrix composites which can overcome their inherent poor densification and improve their mechanical and antioxidation properties.However,the morphology and thickness regulation of ceramic coatings on graphite particles are still a great challenge.Herein,SiC-coated graphite(graphite@SiC)powders were prepared by nitriding combustion synthesis using Si and graphited mesocarbon microbead(MCMB)as raw powders with polytetrafluoroethylene(PTFE)as a promoter.The effects of the PTFE content and the Si/MCMB molar ratio on the phase composition and coating morphology were investigated.The phase transition and microstructure evolution of a combustion synthesis(CS)process were revealed by a gas-released quenching experiment.When the Si/MCMB molar ratio was 1:3 and the PTFE content was 10 wt%,the thickness of the SiC coating synthesized under 2 MPa N_(2)reached 1.14μm.The corresponding sintered graphite@SiC composite had relative density of 99.2%and flexural strength of 231 MPa,accompanied by a significant improvement in high-temperature antioxidation properties.The as-synthesized graphite@SiC powders with good sinterability and antioxidation properties show great promise for applications in the nuclear industry and other extreme fields. | Biao Zhang Wenqi Xie Huaizhi Lin Zhilei Wei Zhichao Xiao Kai He Zhongqi Shi | 2023 | Journal of Advanced Ceramics2023，12，10： | 0 |
| 13 | Phonon lasing in a hetero optomechanical crystal cavity显示文摘Micro-and nanomechanical resonators have emerged as promising platforms for sensing a broad range of physical properties,such as mass,force,torque,magnetic field,and acceleration.The sensing performance relies critically on the motional mass,mechanical frequency,and linewidth of the mechanical resonator.Herein,we demonstrate a hetero optomechanical crystal(OMC)cavity based on a silicon nanobeam structure.The cavity supports phonon lasing in a fundamental mechanical mode with a frequency of 5.91 GHz,an effective mass of 116 fg,and a mechanical linewidth narrowing in the range from 3.3 MHz to 5.2 kHz,while the optomechanical coupling rate is as high as 1.9 MHz.With this phonon laser,on-chip sensing can be predicted with a resolution of δλ∕λ=1.0×10^(−8).The use of a silicon-based hetero OMC cavity that harnesses phonon lasing could pave the way toward high-precision sensors that allow silicon monolithic integration and offer unprecedented sensitivity for a broad range of physical sensing applications. | KAIYU CUI ZHILEI HUANG NING WU QIANCHENG XU FEI PAN JIAN XIONG XUE FENG FANG LIU WEI ZHANG YIDONG HUANG | 2021 | Photonics Research2021，9，6： | 0 |
| 14 | Continuous SiC skeleton reinforced highly oriented graphite flake composites with high strength and specific thermal conductivity显示文摘Highly oriented graphite-based composites have attracted great attention because of their high thermal conductivity(TC),but the low mechanical properties caused by the inhomogeneous distribution and discontinuity of reinforcements restrict the wide applications.Herein,continuous SiC ceramic skeleton reinforced highly oriented graphite flake(SiC/GF)composites were successfully prepared by combining vacuum filtration and spark plasma sintering.The effect of SiC concentration on the microstructure,flexural strength,and thermophysical properties of the composites was investigated.The GF grains in the composites exhibited high orientation with a Lotgering factor of>88%when the SiC concentration was≤30 wt%,and the SiC skeleton became continuous with the SiC concentration reaching 20 wt%.The formation of continuous SiC skeleton improved the flexural strength of the composites effectively while keeping the TC in a high level.Especially,the composites with 30 wt%SiC exhibited the flexural strength up to 105 MPa,and the specific TC reaching 0.118 W·m^(2)·K^(−1)·kg-1.The composites with excellent flexural strength and thermophysical properties showed significant promise for thermal management applications. | Xiaoyu ZHANG Wenqi XIE Lan SUN Zhilei WEI Zhejian ZHANG Yuanyuan ZHU Jiabin HU Shenghe WANG Zhongqi SHI | 2022 | Journal of Advanced Ceramics2022，11，3： | 0 |
| 15 | Phonon lasing enhanced mass sensor with zeptogram resolution under ambient conditions显示文摘High-sensitivity mass sensors under ambient conditions are essential in various fields such as biological research,gas sensing and environ-mental monitoring.In the current work,a phonon lasing enhanced mass sensor was proposed based on an optomechanical crystal cav-ity under ambient conditions.The phonon lasing was harnessed to achieve ultra-high resolution since it resulted in an extremely nar-row mechanical linewidth(less than 10 kHz).Masses with different weights were deposited on the cavity,it is predicted that the maxi-mum resolution for mass sensing can be 65±19 zg,which approaches the mass order of a protein and an oligonucleotide.This implies the potential application of the proposed method in the biomedical fields such as oligonucleotide drug delivery area and the Human Proteome Project. | Fei Pan Kaiyu Cui Yidong Huang Ziming Chen Ning Wu Guoren Bai Zhilei Huang Xue Feng Fang Liu &Wei Zhang | 2023 | Chip2023，2，3： | 0 |
| 16 | Phonon and photon lasing dynamics in optomechanical cavities显示文摘Lasers differ from other light sources in that they are coherent,and their coherence makes them indispensable to both fundamental research and practical application.In optomechanical cavities,photon and phonon lasing is facilitated by the ability of photons and phonons to interact intensively and excite one another coherently.The lasing linewidths of both phonons and photons are critical for practical application.This study investigates the lasing linewidths of photons and phonons from the underlying dynamics in an optomechanical cavity.We find that the linewidths can be accounted for by two distinct physical mechanisms in two regimes,namely the normal regime and the reversed regime,where the intrinsic optical decay rate is either larger or smaller than the intrinsic mechanical decay rate.In the normal regime,an ultra-narrow spectral linewidth of 5.4 kHz for phonon lasing at 6.22 GHz can be achieved regardless of the linewidth of the pump light,while these results are counterintuitively unattainable for photon lasing in the reversed regime.These results pave the way towards harnessing the coherence of both photons and phonons in silicon photonic devices and reshaping their spectra,potentially opening up new technologies in sensing,metrology,spectroscopy,and signal processing,as well as in applications requiring sources that offer an ultra-high degree of coherence. | Jian Xiong Zhilei Huang Kaiyu Cui Xue Feng Fang Liu Wei Zhang Yidong Huang | 2023 | Fundamental Research2023，3，1： | 0 |
| 17 | Pore-water geochemistry in methane-seep sediments of the Makran accretionary wedge off Pakistan:Possible link to subsurface methane hydrate显示文摘Cold seeps are pervasive along the continental margin worldwide,and are recognized as hotspots for elemental cycling pathway on Earth.In this study,analyses of pore water geochemical compositions of one-400 cm piston core(S3)and the application of a mass balance model are conducted to assess methane-associated biogeochemical reactions and uncover the relationship of methane in shallow sediment with gas hydrate reservoir at the Makran accretionary wedge off Pakistan.The results revealed that approximately 77%of sulfate is consumed by the predominant biogeochemical process of anaerobic oxidation of methane.However,the estimated sulfate-methane interface depth is-400 cm below sea floor with the methane diffusive flux of 0.039 mol/(m^(2)·a),suggesting the activity of methane seepage.Based on the δ^(13)C_(DIC) mass balance model combined with the contribution proportion of different dissolved inorganic carbon sources,this study calculated the δ^(13)C of the exogenous methane to be-57.9‰,indicating that the exogenous methane may be a mixture source,including thermogenic and biogenic methane.The study of pore water geochemistry at Makran accretionary wedge off Pakistan may have considerable implications for understanding the specific details on the dynamics of methane in cold seeps and provide important evidence for the potential occurrence of subsurface gas hydrate in this area. | Xianrong Zhang Jianming Gong Zhilei Sun Jing Liao Bin Zhai Libo Wang Xilin Zhang Cuiling Xu Wei Geng | 2021 | Acta Oceanologica Sinica2021，40，9： | 0 |
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