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| 1 | Mesoproterozoic age for Xiamaling Formation in North China Plate indicated by zircon SHRIMP dating显示文摘Zircon grains of magmatic origin from tuffite layers in the Xiamaling Formation at Zhaojiashan Village, Xuanhua area, Hebei Province, were used for zircon dating with a Sensitive High-Resolution Ion Microprobe (SHRIMP II), which gives a weighted mean 207Pb/206Pb age of 1366±9 Ma. It shows a very similar age (1368±12 Ma) as the zircon dating from the Xiamaling Formation in Western Hill, Beijing. This age proposes that the Xiamaling Formation in the North China plate should be of Mesoproterozoic, instead of Neoproterozoic based on K-Ar, Ar-Ar dating. The new zircon age also indicates the devel- opment of macrofossils algae from the Mesoproterozoic age. | GAO LinZhi ZHANG ChuanHeng SHI XiaoYing SONG Biao WANG ZiQiang LIU YaoMing | 2008 | Chinese Science Bulletin2008，53，17： | 68 |
| 2 | Soybean GmMYB76, GmMYB92, and GmMYB177 genes confer stress tolerance in transgenic Arabidopsis plants显示文摘MYB 类型抄写因素包含保存 MYB 约 50 氨基酸的 DNA 有约束力的领域并且涉及植物生长,开发,新陈代谢和应力的许多方面的规定回答。从大豆植物,我们识别了 156 GmMYB 基因用我们的以前获得了 206 MYB unigenes,并且 48 被发现有全身的开读物的框架。所有这些识别基因的表情被检验,并且我们发现 43 基因的表情与骆驼毛的织物,盐,干旱或冷应力在处理之上被改变。三 GmMYB 基因, GmMYB76, GmMYB92 和 GmMYB177,为进一步的分析被选择。用酵母试金系统, GmMYB76 和 GmMYB92 被发现有 transactivation 活动和罐头形式 homodimers。GmMYB177 不看起来举办 transactivation 活动,但是能与 GmMYB76 形成 heterodimers。酵母一个混血儿试金表明三 GmMYBs 能绑在 cis 元素的所有梭织 AAC GGT TTT TT 和 CCG GAA AAA AGG 在,但是与不同亲密关系,并且 GmMYB92 能也绑在 TCT CAC CTA CC。转基因的 Arabidopsis 植物 overexpressing GmMYB76 或 GmMYB177 在盐和结冰忍耐比 GmMYB92 转基因的植物显示出更好的性能。然而,这些转基因的植物与野类型的植物比较在萌芽舞台展出了减少的敏感到骆驼毛的织物处理。三 GmMYB 基因差别除了他们压力应答的基因的一个普通子集的规定影响了压力应答的基因的一个子集。这些结果显示三 GmMYB 基因可以在压力忍耐起微分作用,可能通过压力应答的基因的规定。 | Yong Liao Hong-Feng Zou Hui-Wen Wang Wan-Ke Zhang Biao Ma Jin-Song Zhang Shou-Yi Chen | 2008 | Cell Research2008，18，10： | 70 |
| 3 | Petrogenesis and dating of the Kangding complex,Sichuan Province显示文摘An analysis of major and trace element geochemistry and SHRIMP U-Pb zircon dating of mafic, intermediate, and felsic rocks from the Mianning metamorphic complex of Si- chuan Province was conducted. One of our conclusions is that a majority of the zircons crystal- lized between 721 and 773 Ma in a magmatic regime. The complexes contain early to late Pa- leo-proterozoic relict zircons from ancient continental crust. The oldest age, 2468 Ma, may rep- resent the basement of the Yangtze block. Overgrowth zircon rims and palingenetic zircons have been observed and dated, and are believed to have formed after crystallization, during Paleozoic and Mesozoic metamorphic-anatexis. We also conclude that depletion of Nb, Ta, HREE, in a spider-diagram normalized to primitive mantle and calc-alkaline association, implies that they formed in island-arc or under-plating settings. | CHEN Yuelong 1 , LUO Zhaohua 1 , ZHAO Junxiang, LI Zhihong, ZHANG Hongfei & SONG Biao 3 1. Faculty of Earth Sciences and Natural Resources, China University of Geosciences, Beijing 100083, China 2. Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074, China 3. Beijing SHRIMP Center, Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037, China | 2005 | Science China Earth Sciences2005，48，5： | 40 |
| 4 | Seismic Sequence in Carbonate Rocks By Vibrational Liquefaction显示文摘On the basis of the records of strong seismic events taking place in soft carbonate sediments, a new seismic sequence system of vibrational liquefaction is established, which consists of a series of units, such as escaped structure of micrite veins and liquefied deformation formed in the period of seismic liquefaction, land subsidence structure after liquefaction, tsunamic hummocky and turbidite produced by seismic events, This sequence is a generalization and summation of field observation in vast areas, which shows the whole process of a strong seismic event and provides an unified theoretical explanation. The pattern of the seismic sequence by vibrational liquefaction provides one of correlation standards for geologists in the field to discriminate events in carbonate sequences. Based on the pattern of seismic sequence, the authors first advance a new conception of the Palaeo-Tanlu (Tancheng-Lujiang) Zone and discuss primarily its geological significations. | Qiao Xiufu, Song Tianrui, Gao Linzhi, Peng Yang, Li Haibing, Gao Mai, Song Biao and Zhang QiaodaInstitute of Geology, Chinese Academy of Geological Sciences, Beijing | 1994 | Acta Geologica Sinica(English Edition)1994，68，3： | 39 |
| 5 | Reclassification of the Meso- and Neoproterozoic Chronostratigraphy of North China by SHRIMP Zircon Ages显示文摘High-quality zircon U-Pb ages acquired from Meso- and Neoproterozoic strata in North China in recent years has provided a high-resolution chronostratigraphic framework for dating. A basis of this high-level chronostratigraphic system provides the foundation for a global Precambrian study and stratigraphic correlation and so recent geological studies have focused attention on systemic SHRIMP zircon dating. A chronology of Meso- and Neoproterozoic strata and the time of origin of the overlying Changcheng System is given on the basis of new SHRIMP zircon dating from the Qianxi Complex and diabase of the Chuanlinggou Formation. A new tectonostratigraphy for a Neoproterozoic chronostratigraphic framework in the southeastern margin of the North China continent is underpinned by the new SHRIMP zircon dating of a Neoproterozoic mafic magma diabase in the Jiao-Liao-Xu-Huai Sub-Province. | GAO Linzhi ZHANG Chuanheng LIU Pengju TANG Feng SONG Biao DING Xiaozhong | 2009 | Acta Geologica Sinica(English Edition)2009，83，6： | 36 |
| 6 | Geochronology of Baogutu porphyry copper deposit in Western Junggar area, Xinjiang of China显示文摘Baogutu copper deposit in Western Junggar area is a mesoscopic porphyry deposit found in recent years. Study on its geochronology will help further understand ore genesis and regional ore-forming pattern. A series of small quartz-diorite and granodiorite stocks outcrop at Baogutu area, numbered I―X according to their size. A detailed exploration on Number V stock confirmed it as a mesoscopic scale copper deposit, and various exploration work has been carried out on other stocks with ore-forming evidence. This paper studies geochronology of Number V stock using zircon SHRIMP U-Pb and single mineral K-Ar method. Twenty-five SHRIMP ages yield two 206Pb/238U weighed mean ages of 335.6 ± 7.8 Ma and 311.4 ± 3.3 Ma respectively. The older date is considered to be inherited zircon from either surrounding rock tuff or deep granitoid batholith, whereas the younger date is the formation age of ore-bearing intrusion. K-Ar ages of ore-forming biotites, 296.0 ± 3.7 Ma and 297.3 ± 3.8 Ma, in combination with Re-Os age of molybdenite, 310 Ma, confirm the ore-forming age of 310-296 Ma. Granophyre and dioritic porphyrite dikes cut Number V stock and their K-Ar ages range from 278 to 240 Ma, which confine the lower boundary of the mineralization. The framework of Baogutu ore-forming geochrono-logy can be established based on these data. | LIU YuLin GUO LiShuang LIU YuDe SONG HuiXia SONG Biao ZHANG Rui XU FaJun ZHANG YunXiao | 2009 | Science China Earth Sciences2009，52，10： | 33 |
| 7 | Early Paleozoic granite in Nujiang River of northwest Yunnan in southwestern China and its tectonic implications显示文摘沿着在西方的云南的中国缅甸边阶的 Nujiang 区域收到了很多注意并且被认为是西藏的高原的向东南的逃跑的重要隧道。这条隧道被红 River-Ailao 山左文字的 strick 滑倒差错在这条隧道以内在西方在东方和英雄传奇 Gaoligong 正确文字的 strick 滑倒差错毗邻,它仍然不对贡尚·布洛克哪个构造单位合适清楚。尽管一些研究人员建议它是 Sundaland 岩层的北方结束,它的构造定义是相当模糊的。这篇论文报导我们 U-Pb 同位素的 geochronological 在贡尚·布洛克以内在 Gudang 片麻岩的花岗石上学习的新锆石。这研究在理解起源和西北的云南的构造环境起一个重要作用。 | SONG ShuGuang JI JianQing WEI ChunJing SU Li ZHENG YaDong SONG Biao ZHANG LiFei | 2007 | Chinese Science Bulletin2007，52，17： | 31 |
| 8 | Terrestrial carbon sinks in China and around the world and their contribution to carbon neutrality显示文摘Enhancing the terrestrial ecosystem carbon sink(referred to as terrestrial C sink) is an important way to slow down the continuous increase in atmospheric carbon dioxide(CO_(2)) concentration and to achieve carbon neutrality target.To better understand the characteristics of terrestrial C sinks and their contribution to carbon neutrality,this review summarizes major progress in terrestrial C budget researches during the past decades,clarifies spatial patterns and drivers of terrestrial C sources and sinks in China and around the world,and examines the role of terrestrial C sinks in achieving carbon neutrality target.According to recent studies,the global terrestrial C sink has been increasing from a source of (-0.2±0.9) Pg C yr^(-1)(1 Pg=1015g)in the 1960s to a sink of (1.9±1.1) Pg C yr^(-1) in the 2010s.By synthesizing the published data,we estimate terrestrial C sink of 0.20–0.25 Pg C yr^(-1) in China during the past decades,and predict it to be 0.15–0.52 Pg C yr^(-1) by 2060.The terrestrial C sinks are mainly located in the mid-and high latitudes of the Northern Hemisphere,while tropical regions act as a weak C sink or source.The C balance differs much among ecosystem types:forest is the major C sink;shrubland,wetland and farmland soil act as C sinks;and whether the grassland functions as C sink or source remains unclear.Desert might be a C sink,but the magnitude and the associated mechanisms are still controversial.Elevated atmospheric CO_(2) concentration,nitrogen deposition,climate change,and land cover change are the main drivers of terrestrial C sinks,while other factors such as fires and aerosols would also affect ecosystem C balance.The driving factors of terrestrial C sink differ among regions.Elevated CO_(2) concentration and climate change are major drivers of the C sinks in North America and Europe,while afforestation and ecological restoration are additionally important forcing factors of terrestrial C sinks in China.For future studies,we recommend the necessity for intensive and long-term ecosystem C monitoring over broad geographic scale to improve terrestrial biosphere models for accurately evaluating terrestrial C budget and its dynamics under various climate change and policy scenarios. | Yuanhe Yang Yue Shi Wenjuan Sun Jinfeng Chang Jianxiao Zhu Leiyi Chen Xin Wang Yanpei Guo Hongtu Zhang Lingfei Yu Shuqing Zhao Kang Xu Jiangling Zhu Haihua Shen Yuanyuan Wang Yunfeng Peng Xia Zhao Xiangping Wang Huifeng Hu Shiping Chen Mei Huang Xuefa Wen Shaopeng Wang Biao Zhu Shuli Niu Zhiyao Tang Lingli Liu Jingyun Fang | 2022 | Science China(Life Sciences)2022，65，5： | 32 |
| 9 | High-entropy ceramics:Present status,challenges,and a look forward显示文摘High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging of this new family of materials has brought new opportunities for material design and property tailoring.Distinct from metals,the diversity in crystal structure and electronic structure of ceramics provides huge space for properties tuning through band structure engineering and phonon engineering.Aside from strengthening,hardening,and low thermal conductivity that have already been found in high-entropy alloys,new properties like colossal dielectric constant,super ionic conductivity,severe anisotropic thermal expansion coefficient,strong electromagnetic wave absorption,etc.,have been discovered in HECs.As a response to the rapid development in this nascent field,this article gives a comprehensive review on the structure features,theoretical methods for stability and property prediction,processing routes,novel properties,and prospective applications of HECs.The challenges on processing,characterization,and property predictions are also emphasized.Finally,future directions for new material exploration,novel processing,fundamental understanding,in-depth characterization,and database assessments are given. | Huimin XIANG Yan XING Fu-zhi DAI Hongjie WANG Lei SU Lei MIAO Guojun ZHANG Yiguang WANG Xiwei QI Lei YAO Hailong WANG Biao ZHAO Jianqiang LI Yanchun ZHOU | 2021 | Journal of Advanced Ceramics2021，10，3： | 28 |
| 10 | Regulating effects of arsenic trioxide on cell death pathways and inflammatory reactions of pancreatic acinar cells in rats显示文摘背景煽动性的 cytokines 在尖锐胰腺炎的发展起一个关键作用,这被接受,那么堵住煽动性的反应的开始可以减轻尖锐胰腺炎的病理学的变化。我们在 vitro 在胰腺的 acinar 房间的 apoptosis 和 oncosis 上学习了砷三氧化物(As2O3 ) 的规章的效果,在尖锐 pancreatitis.Methods 上的 vivo 和它的治疗学的效果,胰腺的 acinar 房间被 collagenase 消化方法孤立。孤立的胰腺的 acinar 房间的 Apoptosis 和 oncosis 与 Hoechst 33258+PI 或 Annexin V+PI 被检测两倍荧光灯的染色。淀粉酶并且喂奶脱氢酶版本被测量。尖锐胰腺炎被 caerulein 的 intraperitoneal 注射在 Wistar 老鼠导致,并且 apoptosis 与把方法标记的终端 dUTP 刻痕结束被检测。肿瘤 necorsis 因素(TNF-) mRNA, myeloperoxidase,原子 factor-B 并且胰腺的损坏的组织学的分级是在那里的 measured.Results 是增加的 apoptosis 但是在有 As2O3 的处理以后的胰腺的 acinar 房间的减少的 oncosis。层次喂奶脱氢酶和淀粉酶版本显著地在在对待的 As2O3 的对待的 group.Myeloperoxidase 内容,TNF- mRNA 水平,原子 factor-B 激活和病理学的分数组织的 As2O3 被减少比在未经治疗的 group.Conclusions As2O3 能导致 apoptosis 和胰腺的 acinar 的还原剂 oncosis 的显著地低房间,因此导致 acinar 房间的 endocellular 酶的减少的版本,减少了煽动性的房间渗入并且减少 inflamma | XUE Dong-bo ZHANG Wei-hui YUN Xiao-guang SONG Chun ZHENG Biao SHI Xing-ye WANG Hai-yang | 2007 | Chinese Medical Journal2007，，8： | 26 |
| 11 | Chinese Trauma Surgeon Association for management guidelines of vacuum sealing drainage application in abdominal surgeries-Update and systematic review显示文摘Vacuum sealing drainage (VSD) is frequently used in abdominal surgeries. However, relevant guidelines are rare. Chin ese Trauma Surge on Associati on orga nized a committee composed of 28 experts across China in July 2017, aiming to provide an evidence-based recommendation for the application of VSD in abdominal surgeries.Eleven questions regarding the use of VSD in abdominal surgeries were addressed:(1) which type of materials should be respectively chosen for the intraperitoneal cavity, retroperitoneal cavity and superficial incisions?(2) Can VSD be preventively used for a high-risk abdominal incision w让h primary suture?(3) Can VSD be used in severely contaminated/infected abdominal surgical sites?(4) Can VSD be used for temporary abdominal cavity closure under some special conditions such as severe abdominal trauma, infection, liver transplantation and intra-abdominal volume increment in abdominal compartment syndrome?(5) Can VSD be used in abdominal organ inflammation, injury, or postoperative drainage?(6) Can VSD be used in the treatment of intestinal fistula and pancreatic fistula?(7) Can VSD be used in the treatment of intra-abdominal and extra-peritoneal abscess?(8) Can VSD be used in the treatment of abdominal wall wounds, wound cavity, and defects?(9) Does VSD in crease the risk of bleeding?(10) Does VSD increase the risk of intestinal wail injury?(11) Does VSD increase the risk of peritoneal adhesion? Focusing on these questions, evidence-based recommendations were given accordingly. VSD was strongly recommended regarding the questions 2-4. Weak recommendations were made regarding questions 1 and 5-11. Proper use of VSD in abdominal surgeries can lower the risk of infection in abdominal incisions with primary suture, treat severely contaminated/infected surgical sites and facilitate temporary abdominal cavity closure. | Yang Li Pei-Yuan Li Shi-Jing Sun Yuan-Zhang Yao Zhan-Fei Li Tao Liu Fan Yang Lian-Yang Zhang Xiang-Jun Bai Jing-Shan Huo Wu-Bing He Jun Ouyang Lei Peng Ping Hu Yan-An Zhu Ping Jin Qi-Feng Shao Yan-Feng Wang Rui-Wu Dai Pei-Yang Hu Hai-Ming Chen Ge-Fei Wang Yong-Gao Wang Hong-Xu Jin Chang-Ju Zhu Qi-Yong Zhang Biao Shao Xi-Guang Sang Chang-Lin Yin | 2019 | Chinese Journal of Traumatology2019，22，1： | 26 |
| 12 | SHRIMP U-Pb Zircon Geochronology of the Xiaotongguanshan and Shatanjiao Intrusions and Its Petrological Implications in the Tongling Area, Anhui显示文摘This paper determines the crystallization ages of the Xiaotongguanshan quartz monzodiorite and Shatanjiao quartz monzonite porphyry from the Tongling area using the SHRIMP zircon U-Pb method. The crystallization age of the former is 142.8±1.8 Ma; that of the latter is 151.8±2.6 Ma. These data indicate that they were formed during the Late Jurassic (142.8 to 151.8 Ma). Zoned magma chamber was formed because of double diffusive convection. Therefore, the intrusive sequence of magma is generally from quartz monzonite through quartz monzodiorite to pyroxene monzodiorite, i.e. an inverted sequence. | DI Yongjun WU Ganguo ZHANG Da SONG Biao ZANG Wenshuan ZHANG Zhongyi LI Jinwen | 2005 | Acta Geologica Sinica(English Edition)2005，79，6： | 22 |
| 13 | Modification mechanism of cerium on the Al-18Si alloy显示文摘在不同扔的状态下面的高级低共熔体的 Al-Si 合金上的稀土元素铈(Ce ) 的效果被光显微镜和量的图象分析学习了。尺寸和在铸造物的主要的硅的数量随 melt 的增加的 Ce 的增加减少,这被发现。好 facetted 形状的从分叉的形状的同时主要的硅变化。尽管在铸造物的最容易溶解的硅上的修正也随 melt 的增加的 Ce 的增加改善,离开主要的硅的最容易溶解的硅上的修正的效果在到主要的硅的最容易溶解的硅结束上是比那更明显的。修正机制借助于扫描详细被分析电子显微镜与精力装备了 X 光检查和热力学分析的散分析,它在反应和反应平衡的标准吉布斯精力在变化上包括了分析。 | ZHANG Henghua DUAN Haili SHAO Guangjie XU Luoping YIN Junlin YAN Biao | 2006 | Rare Metals2006，25，1： | 23 |
| 14 | Long-term results of endovascular therapy for proximal subclavian arterial obstructive lesions显示文摘背景 Endovascular 治疗是为锁骨下的动脉的局部性的吸藏的一种处理选择。在与 59 个病人一起的长期的经验是在1998年6月和2008年9月之间的 presented.Methods 的这份报告,我们使用了 endovascular 治疗在 59 个病人对待 61 锁骨下的动脉的妨碍的损害( 46 男性和 13 女性,有一个平均数的 34-82 岁变老( 61.9 眠瑩?佃?????????????? | WANG Ke-qin WANG Zhong-gao YANG Bao-zhong YUAN Chao ZHANG Wang-de YUAN Biao XING Tong SONG Sheng-han LI Tan LIAO Chuan-jun ZHANG Yang | 2010 | Chinese Medical Journal2010，，1： | 21 |
| 15 | Genome-wide Transcription Factor Gene Prediction and their Expressional Tissue-Specificities in Maize显示文摘Transcription factors (TFs) are important regulators of gene expression. To better understand TF-encoding genes in maize (Zea mays L.), a genome-wide TF prediction was performed using the updated B73 reference genome. A total of 2 298 TF genes were identified, which can be classified into 56 families. The largest family, known as the MYB superfamily, comprises 322 MYB and MYB-related TF genes. The expression patterns of 2014 (87.64%) TF genes were examined using RNA-seq data, which resulted in the identification of a subset of TFs that are specifically expressed in particular tissues (including root, shoot, leaf, ear, tassel and kernel). Similarly, 98 kernel-specific TF genes were further analyzed, and it was observed that 29 of the kernel-specific genes were preferentially expressed in the early kernel developmental stage, while 69 of the genes were expressed in the late kernel developmental stage. Identification of these TFs, particularly the tissue-specific ones, provides important information for the understanding of development and transcriptional regulation of maize. | Yi Jiang Biao Zeng Hainan Zhao Mei Zhang Shaojun Xie Jinsheng Lai | 2012 | Journal of Integrative Plant Biology2012，54，9： | 20 |
| 16 | Forest Ecosystem Services and Their Values in Beijing显示文摘As the most important ecosystem in Beijing, the forest supports a lot of ecosystem services to local and around communities, which plays a key role in the maintenance of urban ecological security.However, the valuation on the forest ecosystem services based on regional scale could not provide precise and reasonable values for forestry sector management.In this study, we estimated the magnitudes and economic values of the forest ecosystem services in Beijing at sublot level.The economic value of forest ecosystem services in Beijing was estimated to be 19 339.71×10 6 yuan(RMB) in 2004.Among all the ecosystem services indicators we estimated in this study, only fruit, timber and part of the recreation(which only include the tourism income from the forest parks and scenic areas, but not include that from other forest types) were measured in the social economic system.As estimated in this study, more than 82.19% of the economic value of forest ecosystem services could not be measured in the socio-economic statistical system.The importance of forest ecosystem services in Beijing to human welfare was underestimated by the socio-economic system.Therefore, the policies about the eco-compensation of forest ecosystem services should be established to maintain the sustainable supply of the forest ecosystem services in Beijing. | XIE Gaodi LI Wenhua XIAO Yu ZHANG Biao LU Chunxia AN Kai WANG Jixing XU Kang WANG Jinzeng | 2010 | Chinese Geographical Science2010，20，1： | 18 |
| 17 | Poverty alleviation through e-commerce:Village involvement and demonstration policies in rural China显示文摘The diffusion of e-commerce has played a significant role in recent rural economic development in China.E-commerce is also considered as an efficient channel to alleviate poverty in rural China.Voluminous studies have investigated the contribution of e-commerce to agricultural development,yet it is lacking empirical evidence as to the effects of e-commerce on rural poverty alleviation.Since the year of 2014,in order to develop rural e-commerce,Chinese government launched the National Rural E-commerce Comprehensive Demonstration Project.This gradual involvement policy offered a natural experiment for evaluation of e-commerce.Based on village-level survey data from rural China and Heckit method,our study finds that rural e-commerce has a significantly positive effect on rural income.Moreover,the effect is inverted U-shaped for the relative-poverty villages.The estimation of the propensity scores matching model confirms that the results are robust.The following policy recommendations are proposed:(1)policy support to rural e-commerce should prioritize the povertystricken villages.By doing so,the marginal income effects of e-commerce will be maximized.(2)Investment in internet infrastructure and establishment of human resources for e-commerce in rural areas will have spillover effects,increasing rural income through the'digital dividend'. | PENG Chao MA Biao ZHANG Chen | 2021 | Journal of Integrative Agriculture2021，20，4： | 18 |
| 18 | Ethylene Signaling in Rice and Arabidopsis: Conserved and Diverged Aspects显示文摘 | Chao Yang Xiang Lu Biao Ma Shou-Yi Chen Jin-Song Zhang | 2015 | Molecular Plant2015，8，4： | 17 |
| 19 | A PP2C-1 Allele Underlying a Quantitative Trait Locus Enhances Soybean l O0-Seed Weight显示文摘栽培大豆可以在驯服期间失去某有用基因 loci。从野大豆的基因的基因渗入能拓宽基因背景并且改进大豆农学的特点。在这研究,通过 recombinant 的整个染色体的定序,生来的线人口源于在野大豆 ZYD7 和栽培大豆 HN44 之间的一个十字,并且为种子重量量的特点 loci 印射,我们发现从野大豆 ZYD7 的磷酸酶 2C-1 ( PP2C-1 )等位基因在种子重量/尺寸贡献增加。PP2C-1 可以由提高覆盖物的房间尺寸并且激活一个子集完成这功能播种特点相关的基因。我们发现 PP2C-1 与 GmBZR1 被联系, Arabidopsis BZR1 的大豆 ortholog,之一在发信号的 brassinosteroid (BR ) 给抄写因素调音,并且便于 dephosphorylated GmBZR1 的累积。相反,有在 N 终点的一些氨基酸的变化的 PP2C-2 等位基因没展出这功能。而且,我们证明 GmBZR1 能在转基因的植物支持种子重量 / 尺寸。通过栽培大豆就职的分析,我们发现 40% 检验就职没有 PP2C-1 等位基因,建议这些就职能被这等位基因的介绍改进。一起拿,我们的学习识别精英等位基因 PP2C-1,它能在由分子帮助繁殖的这等位基因的那操作可以增加的大豆,和针尖提高种子重量或尺寸在大豆的生产和另外的荚 / 庄稼。 | Xiang Lu Qing Xiong Tong Cheng Qing-Tian Li Xin-Lei Liu Ying-Dong Bi Wei Li Wan-Ke Zhang Biao Ma Yong-Cai Lai Wei-Guang Du Wei-Qun Man Shou-Yi Chen Jin-Song Zhang | 2017 | Molecular Plant2017，10，5： | 17 |
| 20 | 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages显示文摘5-Hydroxymethylcytosine (5hmC ) 是被连接了到基因规定和癌症致病的重要哺乳动物的 DNA epigenetic 修正。这里,我们用定序途径的一枝敏感化学基于标签的低输入的猎枪在传播没有房间的 DNA (cfDNA ) 探索了 5hmC 的诊断潜力。我们从七种不同癌症类型的 49 个病人定序没有房间的 5hmC 并且发现了能被用来与高精确性预言癌症类型和阶段的不同特征。明确地,我们发现肺癌症在 cfDNA 导致 5hmC 的进步全球损失,而 hepatocellular 癌和胰腺的癌症在没有房间的 hydroxymethylome 导致疾病特定的变化。我们的 proof-of-principle 结果建议没有房间的 5hmC 签名可以潜在地被使用不仅识别癌症类型而且在一些癌症追踪肿瘤舞台。 | Chun-Xiao Song Senlin Yin Li Ma Amanda Wheeler Yu Chen Yan Zhang Bin Liu Junjie Xiong Weihan Zhang Jiankun Hu Zongguang Zhou Biao Dong Zhiqi Tian Stefanie S Jeffrey Mei-Sze Chua Samuel So Weimin Li Yuquan Wei Jiajie Diao Dan Xie Stephen R Quake | 2017 | Cell Research2017，27，10： | 17 |
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