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| 1 | Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 A resolution显示文摘 | Shishang Dong Peng Yang Guobang Li Baocheng Liu Wenming Wang Xiang Liu Boran Xia Cheng Yang Zhiyong Lou Yu Guo Zihe Rao | 2015 | Protein & Cell2015,6,5: | 6 |
| 2 | Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘 | Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning | 2014 | Chinese Medical Journal2014,,3: | 3 |
| 3 | Synthesis and Characterization of a Silica-Based Drug Delivery System for Spinal Cord Injury Therapy显示文摘Acute inflammation is a central component in the progression of spinal cord injury(SCI).Anti-inflammatory drugs used in the clinic are often administered systemically at high doses,which can paradoxically increase inflammation and result in drug toxicity.A cluster-like mesoporous silica/arctigenin/CAQK composite(MSN-FC@ARCG)drug delivery system was designed to avoid systemic side effects of high-dose therapy by enabling site-specific drug delivery to the spinal cord.In this nanosystem,mesoporous silica was modified with the FITC fluorescent molecule and CAQK peptides that target brain injury and SCI sites.The size of the nanocarrier was kept at approximately 100 nm to enable penetration of the blood–brain barrier.Arctigenin,a Chinese herbal medicine,was loaded into the nanosystem to reduce inflammation.The in vivo results showed that MSN-FC@ARC-G could attenuate inflammation at the injury site.Behavior and morphology experiments suggested that MSN-FC@ARC-G could diminish local microenvironment damage,especially reducing the expression of interleukin-17(IL-17) and IL-17-related inflammatory factors,inhibiting the activation of astrocytes,thus protecting neurons and accelerating the recovery of SCI.Our study demonstrated that this novel,silica-based drug delivery system has promising potential for clinical application in SCI therapy. | Guodong Sun Shenghui Zeng Xu Liu Haishan Shi Renwen Zhang Baocheng Wang Changren Zhou Tao Yu | 2019 | Nano-Micro Letters2019,11,2: | 1 |
| 4 | Study of silicon wafer cleaning effects using clean solutions containing surfactants and chelates显示文摘 | CAO Baocheng YU Xinhao MA Jin | 2001 | Chinese Journal of Semiconductors2001,22,9: | 1 |
| 5 | Existence and features of the myodural bridge in gentoo penguins:a morphological study显示文摘Recent studies have evidenced that the anatomical structure now known as the myodural bridge(MDB)connects the suboccipital musculature to the cervical spinal dura mater(SDM).In humans,the MDB passes through both the posterior atlanto-occipital and the posterior atlanto-axial interspaces.The existence of the MDB in various mammals,including flying birds(Rock pigeons and Gallus domesticus)has been previously validated.Gentoo penguins are the world's fastest diving birds.The present study was therefore carried out to investigate the existence and characteristics of the MDB in Gentoo penguin,a non-flying,marine bird that can dive.For this study,six Gentoo penguin specimens were dissected to observe the existence and composition of their MDB. | Cheng Chen Yu Shengbo Chi Yanyan Tan Guangyuan Yan Baocheng Zheng Nan Sui Hongjin | 2021 | 解剖学杂志2021,44,S01: | 1 |
| 6 | Powered-descent landing GNC system design and flight results for Tianwen-1 mission显示文摘The powered-descent landing(PDL)phase of the Tianwen-1 mission began with composite backshell–parachute(CBP)separation and ended with landing-rover touchdown.The main tasks of this phase were to reduce the velocity of the lander,perform the avoidance maneuver,and guarantee a soft touchdown.The PDL phase overcame many challenges:performing the divert maneuver to avoid collision with the CBP while simultaneously avoiding large-scale hazards;slowing the descent from approximately 95 to 0 m/s;performing the precise hazard-avoidance maneuver;and placing the lander gently and safely on the surface of Mars.The architecture and algorithms of the guidance,navigation,and control system for the PDL phase were designed;its execution resulted in Tianwen-1’s successful touchdown in the morning of 15 May 2021.Consequently,the Tianwen-1 mission achieved a historic autonomous landing with simultaneous hazard and CBP avoidance. | Xiangyu Huang Chao Xu Jinchang Hu Maodeng Li Minwen Guo Xiaolei Wang Yu Zhao Baocheng Hua Yunpeng Wang | 2022 | Astrodynamics2022,6,1: | 1 |
| 7 | A high-resolution transcriptomic atlas depicting nitrogen fixation and nodule development in soybean显示文摘Although root nodules are essential for biological nitrogen fixation in legumes,the cell types and molecular regulatory mechanisms contributing to nodule development and nitrogen fixation in determinate nodule legumes,such as soybean(Glycine max),remain incompletely understood.Here,we generated a single-nucleus resolution transcriptomic atlas of soybean roots and nodules at 14 days post inoculation(dpi)and annotated 17 major cell types,including six that are specific to nodules.We identified the specific cell types responsible for each step in the ureides synthesis pathway,which enables spatial compartmentalization of biochemical reactions during soybean nitrogen fixation.By utilizing RNA velocity analysis,we reconstructed the differentiation dynamics of soybean nodules,which differs from those of indeterminate nodules in Medicago truncatula.Moreover,we identified several putative regulators of soybean nodulation and two of these genes,GmbHLH93 and GmSCL1,were as-yet uncharacterized in soybean.Overexpression of each gene in soybean hairy root systems validated their respective roles in nodulation.Notably,enrichment for cytokinin-related genes in soybean nodules led to identification of the cytokinin receptor,GmCRE1,as a prominent component of the nodulation pathway.GmCRE1 knockout in soybean resulted in a striking nodule phenotype with decreased nitrogen fixation zone and depletion of leghemoglobins,accompanied by downregulation of nodule-specific gene expression,as well as almost complete abrogation of biological nitrogen fixation.In summary,this study provides a comprehensive perspective of the cellular landscape during soybean nodulation,shedding light on the underlying metabolic and developmental mechanisms of soybean nodule formation. | Baocheng Sun Yu Wang Qun Yang Han Gao Haiyu Niu Yansong Li Qun Ma Qing Huan Wenfeng Qian Bo Ren | 2023 | Journal of Integrative Plant Biology2023,65,6: | 0 |
| 8 | Particle-Wave Dualism in Nanoconfined Space:Ultrafast Substance Flow显示文摘Many researchers,however,found that(1)the flow of both liquid and gas through nanoscale pores is one to even seven orders of magnitude faster than that would be predicted from the classic Newton’s mechanic theories,such as the Hagen-Poiseuille equation,the Bernoulli’s principle,the Knudsen theory;(2)the seeming contradiction that K+channels conduct K+ions at maximal throughput rates while not permeating slightly smaller Na+ions,which have perplexed scientists for decades.Herein we propose a possible explanation for the above phenomena based on the Wave-Particle Dualism.The quantum effect on ultrafast flow could possibly provide a new perspective for studying the nature of the ion and molecule channels,which are the backbones for the biology,and possibly promote the development of new methods for energy conversion,desalination of sea water and even information systems. | GAO Pengcheng MA Qun LIU Rui LOU Xiaoding HUANG Yu ZHANG Baocheng XIA Fan | 2022 | Chemical Research in Chinese Universities2022,38,4: | 0 |
| 9 | Multi-Objective Optimal Design of the Wind-Wave Hybrid Platform with the Coupling Interaction显示文摘An offshore wind-wave hybrid platform could consistently and cost-effectively supply renewable power.A multi-objective optimization process is proposed for a hybrid platform with hydrodynamic coupling interaction.The effects of various critical structural parameters,spacing values,and wave directions are studied for higher energy capture and offshore platform stability.Approximation models of various key parameters are established to optimize the hybrid system,with the objects of the power capture width ratio and the stability index of the platform.The optimization results are affected by the hydrodynamic coupling interaction,with a tendency to affect the higher frequency of hydrodynamic performance in the hybrid system.After the optimization,an appropriate spacing value effectively improves energy capture performance.The optimal array distance D_(Ff),D_(Fp),the optimal structural parameters R_(p),r_(p),d_(f),r_(f),and B_(PTO)are 11.57,12.75,5.1,3.3,1.5,6.5 m,and 80436 Nm s^(-1),respectively.The peak value of the wave energy converter capture width ratio in the hybrid system increases by almost 50%,with a 54%decrease in the stability index. | DENG Ziwei ZHANG Baocheng MIAO Yu ZHAO Bo WANG Qiang ZHANG Kaisheng | 2023 | Journal of Ocean University of China2023,22,5: | 0 |
| 10 | Study on Immobilized Algal Cells for Treatment and Recycle of Refinery Wastewater显示文摘Compared to the algal oxidation pond, treatment of wastewater using the immobilized algal cell technology has excellent effect, which not only can effectively avoid the disadvantage of oxidation pond,but can also remarkably improve the efficiency of treating system and the effluent quality. When the treating system operates under an optimal control conditions, such as a 55% loading rate, an illumination intensity of 2500-3500 lux and a hydraulic residence time of 4 hours, the COD and ammonia nitrogen removal can reach 90%. Water after deep treatment can comply with the requirement of the refinery for the quality of recycled water. | Yu Baocheng Liu Deqi Dong Lihua Li Gang | 2005 | China Petroleum Processing & Petrochemical Technology2005,7,3: | 0 |