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| 1 | Characterization of the receptor-binding domain(RBD)of 2019 novel coronavirus:implication for development of RBD protein as a viral attachment inhibitor and vaccine显示文摘The outbreak of Coronavirus Disease 2019(COVID-19)has posed a serious threat to global public health,calling for the development of safe and effective prophylactics and therapeutics against infection of its causative agent,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),also known as 2019 novel coronavirus(2019-nCoV).The CoV spike(S)protein plays the most important roles in viral attachment,fusion and entry,and serves as a target for development of antibodies,entry inhibitors and vaccines.Here,we identified the receptor-binding domain(RBD)in SARS-CoV-2 S protein and found that the RBD protein bound strongly to human and bat angiotensin-converting enzyme 2(ACE2)receptors.SARS-CoV-2 RBD exhibited significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD and could block the binding and,hence,attachment of SARS-CoV-2 RBD and SARS-CoV RBD to ACE2-expressing cells,thus inhibiting their infection to host cells.SARS-CoV RBD-specific antibodies could crossreact with SARS-CoV-2 RBD protein,and SARS-CoV RBD-induced antisera could cross-neutralize SARS-CoV-2,suggesting the potential to develop SARS-CoV RBD-based vaccines for prevention of SARS-CoV-2 and SARS-CoV infection. | Wanbo Tai Lei He Xiujuan Zhang Jing Pu Denis Voronin Shibo Jiang Yusen Zhou Lanying Du | 2020 | Cellular & Molecular Immunology2020，17，6： | 35 |
| 2 | Long-term changes in the fishery ecosystem structure of Laizhou Bay,China显示文摘Laizhou Bay provides a critical spawning and nursery habitat for many fishery species,including commercially important species,such as Fenneropenaeus chinensis and Larimichthys polyactis.The bay is severely stressed due to high fishing pressure and environmental changes.Based on the long-term ecosystem surveys in Laizhou Bay during the main spawning period(May) of most fishery species from 1959 to 2008,the responses of the Laizhou Bay fishery ecosystem were analyzed here,including regime shifts in species composition,biomass,species diversity,zooplankton,phytoplankton,and environmental variables.The dominant species of large-size and high economic value(e.g.Trichiurus haumela,L.polyactis) have been replaced by the short-lived,low-trophic-level planktivorous pelagic species(e.g.Setipinna taty,Engraulis japonicus) since the 1980s,and it is probable that the small-sized pelagic fishes have been recently replaced by invertebrates(e.g.Oratosquilla oratoria,Crangon affinis).The biomass of fishery resources declined continuously from 423.6 kg haul?1 h?1 in 1959 to 164.6 kg haul?1 h?1 in 1982,37.7 kg haul?1 h?1 in 1993,and less than 8 kg haul?1 h?1 in 1998-2008.Moreover,the biomass of zooplankton showed an increasing trend during 1959-2006,but showed a slight decline in 2008.The abundance of phytoplankton increased from 1959 through 1982,decreased substantially in 1993,and increased again until 2004.More recently,however,the phytoplankton abundance was very low.The sea surface temperature(SST) and sea bottom temperature(SBT) in May increased by 0.23°C a?1 and 0.16°C a?1,respectively,during 1982-2008.The salinity in May showed large fluctuations and reached its lowest values in 2004 and 2006.The ratio of dissolved inorganic nitrogen(DIN) to dissolved inorganic phosphate(DIP) increased.However,the dissolved silicon(DSi):DIP and DSi:DIN ratios decreased to a low level during 1959-2008.These changes seriously impacted primary production,and cascade effects then changed the structure and function of the fishery ecosystem.Further analysis indicated that multiple stresses caused the alterations in the structure of the Laizhou Bay fishery ecosystem.The top-down effect was identified as the main influence on the fishery species(at the top of the food chain) over the past five decades due to the increasing fishing pressure,whereas the bottom-up effect increased over the past three decades due to the strong variations in the environment. | JIN XianShi SHAN XiuJuan LI XianSen WANG Jun CUI Yi ZUO Tao | 2013 | Science China Earth Sciences2013，56，3： | 31 |
| 3 | Genome analysis of Taraxacum kok-saghyz Rodin provides new insights into rubber biosynthesis显示文摘The Russian dandelion Taraxacum kok-saghyz Rodin(TKS), a member of the Composite family and a potential alternative source of natural rubber(NR) and inulin, is an ideal model system for studying rubber biosynthesis. Here we present the draft genome of TKS, the first assembled NR-producing weed plant. The draft TKS genome assembly has a length of 1.29 Gb, containing 46 731 predicted protein-coding genes and68.56% repeats, in which the LTR-RT elements predominantly contribute to the genome enlargement. We analyzed the heterozygous regions/genes, suggesting its possible involvement in inbreeding depression.Through comparative studies between rubber-producing and non-rubber-producing plants, we found that enzymes of the mevalonate(MVA) pathway and rubber elongation might be critical for rubber biosynthesis, and several key isoforms have been isolated and shown to be predominantly expressed in the latex, indicating their crucial functions in rubber biosynthesis. Moreover, for two important families in rubber elongation, the CPT/CPTL and REF/SRPP families, diverse evolutionary tracks have been revealed. These results provide valuable resources and new insights into the mechanism of NR biosynthesis,and facilitate the development of alternative NR-producing crops. | Tao Lin Xia Xu Jue Ruan Shizhong Liu Shigang Wu Xiujuan Shao Xiaobo Wang Lin Gan Bi Qin Yushuang Yang Zhukuan Cheng Suhua Yang Zhonghua Zhang Guosheng Xiong Sanwen Huang Hong Yu Jiayang Li | 2018 | National Science Review2018，5，1： | 22 |
| 4 | Disentangling the effects of topography and space on the distributions of dominant species in a subtropical forest显示文摘Topography and space are two important factors determining plant species assemblages in forest communities.Quantification of the contribution of these two factors in determining species distribution helps us to evaluate their relative importance in determining species assemblages.This study aims to disentangle the effect of topography and space on the distributions of 14 dominant species in a subtropical mixed forest.Spearman correlation analysis and the torustranslation test were used to test the species–habitat associations.Variation partitioning was used to quantify the relative contributions of topography and space at three sampling scales and three life stages.Correlation analyses and torus-translation tests showed species abundance was mostly correlated with topographic wetness index,vertical distance from the channel network and convexity.Variation partitioning showed that pure topography,pure space and spatially structured topography explained about 2.1 %,41.2 % and 13.8 %of the variation in species distributions,respectively.For nine species,total topography fractions peaked in 20 m quadrats.For ten species,the pure space fractions peaked in 50 m quadrats.For many species,the total topography fraction andthe pure space fraction were larger for the most abundant life stages,which reflected the importance of sampling effect.However,some cases did not follow this trend suggesting that the effects of ecological processes such as habitat filtering,density dependence or dispersal limitation may exceed the sampling effects.In conclusion,we found that spatially structured topography and pure space primarily shaped the distribution of dominant tree species.Furthermore,their effects were both scale- and life stage-dependent. | Qinggang Wang Yaozhan Xu Zhijun Lu Dachuan Bao Yili Guo Junmeng Lu Kuihan Zhang Haibo Liu Hongjie Meng Xiujuan Qiao Handong Huang Mingxi Jiang | 2014 | Chinese Science Bulletin2014，59，35： | 16 |
| 5 | Density dependence and habitat preference shape seedling survival in a subtropical forest in central China显示文摘Aims seedlings are vulnerable to many kinds of fatal abiotic and biotic agents,and examining the causes of seedling dynamics can help understand mechanisms of species coexistence.To disentangle the relative importance of neighborhood densities,habitat factors and phylogenetic relatedness on focal seedling survival,we monitored the survival of 5306 seedlings of 104 species>15 months.We address the following questions:(i)How do neighborhood densities,habitat variables and phylogenetic relatedness affect seedling survival?What is the relative importance of conspecific densities,habitat variables and phylogenetic relatedness to seedling survival?(ii)Does the importance of the neighborhood densities,habitat variables and phylogenetic relatedness vary among growth forms,leaf habits or dispersal modes?specially,does the conspecific negative density dependence inhibit tree and decidu-ous seedlings more compared with shrub and evergreen species?Does density dependence affect the wind and animal-dispersed species equally?Methods We established 135 census stations to monitor seedling dynamics in a 25-ha subtropical forest plot in central China.Conspecific and heterospecific seedling density in the 1-m2 seedling plot and adult basal area within a 20-m radius provided neighborhood density var-iables.mean elevation,convexity and aspect of every 5-×5-m grid with seedling plots were used to quantify habitat characteristics.We calculated the relative average phylodiversity between focal seed-ling and heterospecific neighbors to quantify the species related-ness in the neighborhood.Eight candidate generalized linear mixed models with binominal error distribution were used to compare the relative importance of these variables to seedling survival.akaike’s information criteria were used to identify the most parsimonious models.Important Findingsat the community level,both the neighborhood densities and phylogenetic relatedness were important to seedling survival.We found negative effects of increasing conspecific seedlings,which suggested the existence of species-specific density-dependent mortality.Phylodiversity of heterospecific neighbors was negatively related to survival of focal seedlings,indicating similar habitat preference shared among phylogenetically closely related species may drive seedling survival.The relative importance of neighborhood densities,habitat variables and phylogenetic relatedness varied among ecological guilds.Conspecific densities had significant negative effect for deciduous and wind-dispersed species,and marginally significant for tree seedlings>10 cm tall and animal-dispersed species.Habitat variables had limited effects on seedling survival,and only elevation was related to the sur-vival of evergreen species in the best-fit model.We conclude that both negative density-dependent mortality and habitat preference reflected by the phylogenetic relatedness shape the species coex-istence at seedling stage in this forest. | Junmeng Lu Daniel J.Johnson Xiujuan Qiao Zhijun Lu Qinggang Wang Mingxi Jiang | 2015 | Journal of Plant Ecology2015，8，6： | 12 |
| 6 | Characteristics of ozone vertical profile observed in the boundary layer around Beijing in autumn显示文摘In the autumn of 2008,the vertical profiles of ozone and meteorological parameters in the low troposphere (0-1000 m) were observed at two sites around Beijing,specifically urban Nanjiao and rural Shangdianzi.At night and early morning,the lower troposphere divided into two stratified layers due to temperature inversion.Ozone in the lower layer showed a large gradient due to the titration of NO.Air flow from the southwest brought ozone-rich air to Beijing,and the ozone profiles were marked by a continuous increase in the residual layer at night.The accumulated ozone in the upper layer played an important role in the next day's surface peak ozone concentration,and caused a rapid increase in surface ozone in the morning.Wind direction shear and wind speed shear exhibited different influences on ozone profiles and resulted in different surface ozone concentrations in Beijing. | Zhiqiang Ma Xiaoling Zhang Jing Xu xiujuan Zhao Wei Meng | 2011 | Journal of Environmental Sciences2011，23，8： | 11 |
| 7 | Biological coupling anti-wear properties of three typical molluscan shells—Scapharca subcrenata, Rapana venosa and Acanthochiton rubrolineatus显示文摘Molluscan shells are fascinating examples of highly ordered hierarchical structure and complex organic-inorganic biocomposite material. However, their anti-wear properties were rarely studied especially in the perspective of biological coupling. So in the current study three typical shells, Scapharca subcrenata, Rapana venosa and Acanthochiton rubrolineatus, were selected as coupling models to further study their anti-wear properties. Stereomicroscope and scanning electron microscopic observations showed that all these three shells had specific surface morphologies and complicated section microstructures. Importantly, a special structure, pore canal tubules, was discovered in the shells of Scapharca subcrenata and Acanthochiton rubrolineatus, which probably contributed most to their anti-wear properties. X-ray diffraction and micro-Vikers hardness tester were further adopted to analyze the phase compositions and micro-hardness of the shells. The measured results demonstrated that aragonite was the most extensive phase present in the shell, and possesed a relatively high micro-hardness. In this paper, the shells were described in details in morphology, structure and material with emphasis on the relationship with anti-wear property. The study revealed that the selected seashells possess distinct anti-wear properties by complicated mechanisms involving the integrated functions of multiple biological coupling elements, and this would provide inspiration to the design of new bionic wear resistance components. | XiMei Tian ZhiWu Han XiuJuan Li ZhaoGuo Pu LuQuan Ren | 2010 | Science China(Technological Sciences)2010，53，11： | 10 |
| 8 | Cesium lead halide perovskite triangular nanorods as high-gain medium and effective cavities for multiphoton- pumped lasing显示文摘基于铯铅卤化物 perovskite, nanostructures 在综合 photonics 为非线性的光学和实际频率 upconversion 设备正在答应的高效的抽 multiphoton 的激光。然而,如此的激光的表演高度依赖于材料和洞的质量,它使他们的制造挑战性。此处,我们表明经由蒸汽方法制作的三角形的 nanorods 能作为抽 multiphoton 的激光的获得媒介和有效的洞服务的那铯铅卤化物 perovskite。我们观察了在刺激的放射激光的模式蓝移动在增加的刺激的 fluence 依赖的放射激光系列驱动充满效果的乐队引起的移动,它与 Burstein 苔藓的动力学适合很好。而且,在 CsPbBr 3 nanorods 放射激光的有效 multiphoton 能在一个宽刺激波长范围(700-1,400 nm ) 被认识到。放射激光的 multiphoton 的动力学被解决时间的光致发光光谱学调查,它显示电子洞血浆负责抽 multiphoton 的放射激光。这个工作能在放射激光的频率 upconversion 为铯铅卤化物 perovskite nanostructures 导致新机会和应用设备并且光互连系统。 | Xiaoxia Wang Hong Zhou Shuangping Yuan Weihao Zheng Ying Jiang Xiujuan Zhuang Hongjun Liu Qinglin Zhang Xiaoli Zhu Xiao Wang Anlian Pan | 2017 | Nano Research2017，10，10： | 10 |
| 9 | Functional characteristics of dragonfly wings and its bionic investigation progress显示文摘Dragonfly is one of the most excellent nature flyers,and its wings exhibit excellent functional characteristics through the coupling and synergy of morphology,configuration,structure and material.The functional characteristics presented by dragonfly wings provide an biological inspiration for the investigation and development of aerospace vehicles and bionics flapping aerocraft flapping-wing micro air vehicles.In resent years,some progresses have been achieved in the researches on the wings' geometric structure,material characteristics,flying mechanism and the controlling mode.In this paper,the functional characteristics of the dragonfly wings including flying,self-cleaning,anti-fatigue,vibration elimination and noise reduction are introduced and the effects of their morphology,configuration,structure and material on the functional characteristics are described.Moreover,the current state of the bionic study on the functional characteristics of dragonfly wings is analyzed and its application prospect is depicted. | REN LuQuan LI XiuJuan | 2013 | Science China(Technological Sciences)2013，56，4： | 10 |
| 10 | Detecting protein complexes from DPINs by density based clustering with Pigeon-Inspired Optimization Algorithm显示文摘Detecting protein complexes is crucial to understand principles of cellular organization. Plenty evidences have indicated that sub-graphs with high density in protein-protein interaction(PPI) network, especially dynamic PPI network(DPIN), usually correspond to protein complexes. As a well-known density-based clustering algorithm, Density-Based Spatial Clustering of Applications with Noise(DBSCAN) has been used in many areas due to its simplicity and the ability to detect clusters of different sizes and shapes. However, one of its limitations is that the performance of DBSCAN depends on two specified parameters ε and Min Pts, where εrepresents the maximum radius of a neighborhood from an observing point while Min Pts means the minimum number of data points contained in such a neighborhood. In this article, we develop a new method named as P-DBSCAN to detect protein complexes in DPIN by using Pigeon-Inspired Optimization(PIO) Algorithm to optimize the parameters ε and Min Pts in DBSCAN. The experiments on DIP and MIPS datasets show that P-DBSCAN outperforms the state-of-the-art methods for protein complex detection in terms of several criteria such as precision, recall and f-measure. | Xiujuan LEI Yulian DING Fang-Xiang WU | 2016 | Science China(Information Sciences)2016，59，7： | 9 |
| 11 | A Cost-Effective Co-precipitation Method for Synthesizing Indium Tin Oxide Nanoparticles without Chlorine Contamination显示文摘Indium tin oxide (ITO) nanoparticles with crystallite size of 12.6 nm and specific surface area of 45.7 m 2 ·g-1 were synthesized by co-precipitation method.The indium solution was obtained by dissolving metal indium in HNO3.The tin solution was obtained by dissolving metal tin in HNO3 and followed by stabilizing with citric acid.The free of chlorine ions in the synthesis process brought several advantages:shortening the synthesis time,decreasing the particle agglomeration,decreasing the chlorine content in the ITO nanoparticles and improving the particle sinterability.This is the first time to report the synthesis of ITO nanoparticles free from chlorine contamination without using the expensive metal alkoxides as starting materials. | Haiwen Wang Xiujuan Xu Jianrong Zhang Chunzhong Li | 2010 | Journal of Materials Science & Technology2010，26，11： | 8 |
| 12 | Mett13-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells显示文摘 | QiJason Yao Lina Sang Minghui Lin Xiujuan Yin Wenjie Dong Yuping Gong Bo O. Zhou | 2018 | Cell Research2018，28，9： | 8 |
| 13 | Sequential use of ultraviolet light and chlorine for reclaimed water disinfection显示文摘Several disinfection processes of ultraviolet (UV),chlorine or UV followed by chlorine were investigated in municipal wastewater according to the inactivation of Escherichia coli,Shigella dysenteriae and toxicity formation.The UV inactivation of the tested pathogenic bacteria was not affected by the quality of water.It was found that the inactivated bacteria were obviously reactivated after one day in dark.Fluorescent light irradiation increased the bacteria repair.The increase of UV dosage could cause more damage to bacteria to inhibit bacteria self-repair.No photoreactivation was detected when the UV dose was up to 80 mJ/cm2 for E.coli DH5α,and 23 mJ/cm2 for S.dysenteriae.Nevertheless,sequential use of 8 mJ/cm2 of UV and low concentration of chlorine (1.5 mg/L) could effectively inhibit the photoreactivation and inactivate E.coli below the detection limits within seven days.Compared to chlorination alone,the sequential disinfection decreased the genotoxicity of treated wastewater,especially for the sample with high NH 3-N concentration. | Xiujuan Wang Xuexiang Hu Chun Hu Dongbin Wei | 2011 | Journal of Environmental Sciences2011，23，10： | 8 |
| 14 | Differentiation potential of bone marrow mesenchymal stem cells in duck显示文摘The bone marrow mesenchymal stem cells(MSCs) are multipotent stem cells which can differentiate into mesenchymal cells in vitro.In this study,MSCs in duck were isolated from bone marrow by density gradient centrifuge separation,purified and expanded in the me-dium.The primary MSCs were expanded for 11 passages.The different-passage MSCs were induced to differentiate into osteoblasts and neuron-like cells.Karyotype analysis indicated that MSCs kept diploid condition and the hereditary feature was stable.The different-passage MSCs expressed CD44,ICAM-1 and SSEA-4,but not CD34,CD45 and SSEA-1 when detected by immunofluorescence staining.There was no significant difference among the positive rates of passages 2,6 and 8(P > 0.05),but a significant difference existed among those of passages 2,6,8 and 11(P < 0.05).After the osteogenic inducement was added,the induced different-passage MSCs expressed high-level alkaline phosphatase(ALP),and are positive for tetracycline staining,Alizarin Red staining and Von Kossa staining.After the neural inducement was added,about 70% cells exhibited typical neuron-like phenotype,the induced different-passage MSCs expressed Nestin,neuron-specific enolase(NSE) and glial fibrillary acidic protein(GFAP) when detected by immunofluorescence staining.There was no significant difference among the positive rates of passages 3,4 and 6(P>0.05),but a significant difference existed among those of passages 3,4,6 and 8(P<0.05).These results suggest that MSCs in duck were capable of differentiating into osteoblasts and neuron-like cells in vitro. | Linfeng Li Xiujuan Bai Xuelian Gong Hongkun Liu Lina Chen Weijun Guan Yuehui Ma | 2009 | Journal of Genetics and Genomics2009，36，3： | 8 |
| 15 | Purification of melibiose-binding lectins from two cultivars of Chinese black soybeans显示文摘一二聚 50 kDa melibiose 有约束力的 lectin 从大豆(Glycine 最大) 的栽培变种的种子被孤立,叫了小光滑的黑大豆。隔离过程在胶化过滤在 Superdex 75 上跟随的 Q Sepharose, SP Sepharose 和单音的 Q 上包括了离子交换层析。lectin 在所有三离子 exchangers 上被吸附,并且它展出了与大豆 lectin 的相同的一个 N 终端序列。测试的所有糖, melibiose 最 potently 禁止了 lectin 的 hemagglutinating 活动,它在 pH 3-12 和 0-70 ° C 之间是稳定的。lectin 唤起了最大的 mitogenic 反应在大约象反对 A 的一样的臼齿的集中。然而,反应弱得多。大豆 lectin 分别地与 2.82 μM, 2.6 μM 和 4.1 μM 的 IC 50 象乳癌 MCF7 房间和 hepatoma HepG2 房间的增长一样禁止了 HIV-1 反向的 transcriptase 的活动。没有抗真菌的活动。另一 lectin 从称为很少黑大豆的大豆的不同栽培变种被孤立。lectin 除了一个更大的子单元实质上类似于小光滑的黑大豆 lectin 分子的质量(31 kDa ) ,一项更多的有势力 mitogenic 活动和更低的 thermostability。结果显示大豆的不同栽培变种生产不在每个方面是相同的 lectins。 | Peng Lin Xiujuan Ye TB Ng | 2008 | Acta Biochimica et Biophysica Sinica2008，40，12： | 7 |
| 16 | Geochronological and geochemical constraints on the Cuonadong leucogranite, eastern Himalaya显示文摘First comprehensive investigations of the Cuonadong leucogranite exposed in North Himalayan gneiss dome of southern Tibet are presented in this study.The SIMS U–Pb ages of oscillatory zircon rims scatter in a wide range from 34.1 to 16.0 Ma, and the Cuonadong leucogranite probably emplaced at 16.0 Ma. High-precision ^(40)Ar/^(39)Ar dating on a muscovite sample yields an essentially flat age spectrum with consistent plateau and isochron ages, indicating that the Cuonadong leucogranite cooled below 450 °C at 14 Ma. Based on the youngest zircon U–Pb age and muscovite^(40)Ar/^(39)Ar age, the Cuonadong leucogranite experienced rapid cooling with a rate of 119 °C/Myr from 16 to 14 Ma. The geochronological data of this undeformed leucogranite also suggest that the ductile extension of the South Tibetan Detachment System in the eastern Himalaya ceased by ca. 14 Ma. Furthermore,the initial Sr–Nd isotopic compositions and Nd model ages demonstrate that the leucogranite was derived from metapelitic source within the Greater Himalayan Crystalline Complex. The distinct Ba depletion with high Rb/Sr ratios and negative Eu anomalies make it clear that the leucogranite melts were generated by breakdown of muscovite under fluid-absent conditions. | Jiajia Xie Huaning Qiu Xiujuan Bai Wanfeng Zhang Qiang Wang Xiaoping Xia | 2018 | Acta Geochimica2018，37，3： | 7 |
| 17 | Highly stable lead-free Cs3Bi2I9 perovskite nanoplates for photodetection applications显示文摘Lead halide perovskites have received tremendous attentions recently for their excellent properties such as high light absorption coefficient and long charge carrier diffusion length. However, the stability issues and the existence of toxic lead cations have largely limited their applications in optoelectronic area. Herein, we report the synthesis and investigation of highly stable and lead-free Cs3Bi2I9 perovskite nanoplates for visible light photodetection applications. The Cs3Bi2I9 nanoplates were synthesized through a facile solution-processed method, which is also applicable to various substrates. The achieved nanoplates present very good crystal quality and exhibit excellent long-term stability even exposed in moist air for several months. Photodetectors were constructed based on these high-quality perovskite nanoplates for the first time, and display a maximum photoresponsivity of 33.1 mA/W under the illumination of 450 nm laser, which is six times higher than the solution-synthesized CH3NH3PbI3 nanowire photodetectors. The specific detectivity of these devices can reach up to 10^10 Jones. Additionally, the devices exhibit fast rise and decay time of 10.2 and 37.2 ms, respectively, and highly stable photoswitching behavior with their photoresponse well retaining under alternating light and darkness. This work opens up a new opportunity for stable and low-toxic perovskite-based optoelectronic applications. | Zhaoyang Qi Xianwei Fu Tiefeng Yang Dong Li Peng Fan Honglai Li Feng Jiang Lihui Li Ziyu Luo Xiujuan Zhuang Anlian Pan | 2019 | Nano Research2019，12，8： | 7 |
| 18 | Study on fire retardant mechanism of nano-LDHs in intumescent system显示文摘This paper investigated the fire-retardant mechanism of the nano-LDHs in the intumescent system by the temperature programmed oxidation (TPO). Researches were also conducted to explore the function of the nano-LDHs in the composite fire-retardant agents in air and nitrogen atmosphere, respectively. The results indicated that the nano-LDHs species were responsible for the catalytic oxidation of the rich-carbon compound in oxygen atmosphere. In addition, the nano-LDHs species and their calcinated products at high temperature could increase the carbonaceous residue-shield of the carbon-rich materials, improve the quality and the graphitization degree of the formed char-layer, and accelerate the intumescence and expansion of the melting carbon-rich materials to a certain degree under the oxygen-free condition, leading to the carbonization and expansion of the intumescent layer. | ZHANG ZeJiang LAN Bin MEI XiuJuan XU ChengHua | 2007 | Science China Chemistry2007，50，3： | 7 |
| 19 | Cryotherapy for cirrhosis-based hepatocellular carcinoma: a single center experience from 1595 treated cases显示文摘Cryoablation 是为 hepatocellular 癌(HCC ) 的不太流行的经皮的夺格的治疗,并且关于它的实用性的当前的证据是有限的。我们在与经皮的 cryoablation 对待 1595 个 HCC 案例关于有效性,安全和这治疗的长期的结果给全面侧面报导我们的经验。从 2003 年 1 月到 2013 年 12 月,有 2313 个 HCC 小瘤的 1595 个病人在我们的中心与 2958 个 cryoablation 会议被切除。完全的脱离与 3.4 朠湥浯捩椠獮慴楢楬祴 ? 畢 ? 的一条吝啬的直径为 1893 个小瘤在 1294 个病人被完成 ?? 潣扭湩摥眠瑩 ??? 瑡整畮瑡摥琠敨攠瑸湥 ? 景朠湥浯捩椠獮慴楢楬祴椠 ? 牰浩牡 ? 塖′畴潭 ? 楴獳敵瑡吗?? | Guanghua Rong Wenlin Bai Zheng Dong Chunping Wang Yinying Lu Zhen Zeng Jianhui Qu Min Lou Hong Wang Xudong Gao Xiujuan Chang Linjing An Yan Chen Yongping Yang | 2015 | Frontiers of Medicine2015，9，1： | 7 |
| 20 | Molecular epidemiology demonstrates that imported and local strains circulated during the 2014 dengue outbreak in Guangzhou, China显示文摘The dengue virus(DENV) is a vital global public health issue. The 2014 dengue epidemic in Guangzhou, China, caused approximately 40,000 cases of infection and five deaths. We carried out a comprehensive investigation aimed at identifying the transmission sources in this dengue epidemic. To analyze the phylogenetics of the 2014 dengue strains, the envelope(E) gene sequences from 17 viral strains isolated from 168 dengue patient serum samples were sequenced and a phylogenetic tree was reconstructed. All 17 strains were serotype Ⅰ strains, including 8genotype Ⅰ and 9 genotype V strains. Additionally, 6 genotype Ⅰ strains that were probably introduced to China from Thailand before 2009 were widely transmitted in the 2013 and 2014 epidemics, and they continued to circulate until 2015, with one affinis strain being found in Singapore. The other 2 genotype Ⅰ strains were introduced from the Malaya Peninsula in 2014. The transmission source of the 9 genotype Ⅴ strains was from Malaysia in 2014. DENVs of different serotypes and genotypes co-circulated in the 2014 dengue outbreak in Guangzhou. Moreover, not only had DENV been imported to Guangzhou, but it had also been gradually exported, as the viruses exhibited an enzootic transmission cycle in Guangzhou. | Geng Li Pan Pan Qiuyan He Xiujuan Kong Kailang Wu Wei Zhang Yuntao Liu Huiting Huang Jianbo Liu Zhongde Zhang De Wu Xiaoping Lai Xiaohong Liu Jianguo Wu | 2017 | Virologica Sinica2017，32，1： | 7 |
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