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| 1 | Omental flaps reduces complications after pancreaticoduodenectomy显示文摘BACKGROUND:Major complications after pancreaticoduodenectomy are usually caused by a leaking pancreaticojejunal anastomosis.Omental flaps around various anastomoses were used to prevent the formation of fistula.METHODS:We reviewed 147 patients who had undergone pancreaticoduodenectomy between March 2006 and March2012.The patients were divided into 2 groups according to the application of omental flaps around various anastomoses:group A(101 patients)who underwent omental wrapping procedure;group B(46 patients)who did not undergo the omental wrapping procedure.Perioperative data of the two groups were reviewed to assess the effectiveness of omental flap procedure in the prevention of pancreatic fistula and other complications.RESULTS:No differences were observed in the clinical characteristics between the 2 groups.The incidences of pancreatic fistula(4.0%vs 17.4%),post-pancreatectomy hemorrhage(0vs 6.5%),biliary fistula(1.0%vs 13.0%),and delayed gastric emptying(4.0%vs 17.4%)were significantly less frequent in group A.The overall morbidity(18.8%vs 47.8%)and hospital stay(8.3 vs 9.6 days)were also significantly lower in group A than in group B.CONCLUSIONS:Omental flaps around various anastomoses after pancreaticoduodenectomy can reduce the incidences of pancreatic fistula,biliary fistula,post-pancreatectomy hemorrhage and delayed gastric emptying.This procedure is simple and effective to reduce the overall morbidity after pancreaticoduodenectomy. | Omar J Shah Sadaf A Bangri Manmohan Singh Reyaz A Lattoo Mohammad Y Bhat | 2015 | Hepatobiliary & Pancreatic Diseases International2015,14,3: | 19 |
| 2 | A selective approach to the surgical management of periampullary cancer patients and its outcome显示文摘BACKGROUND: Pancreaticoduodenectomy is a high risk, complex, technically challenging operation associated with significant perioperative morbidity and mortality. This study on the surgical management of periampullary cancer patients is based on our experience in a period of nearly 13 years.METHODS: The study was conducted on two groups of patients: group A included 42 patients who were treated between January 2000 and September 2005 and group B included 134 patients who were treated between October 2005 to October 2012. Preoperative, intraoperative and postoperative details of all these patients were collected, tabulated and analyzed to assess the impact of the selective approach introduced in the department with effect from October 2005.RESULTS: Intraoperative details revealed highly significant differences in the management of the two groups of patients in respect of operative time (250.4 vs 126.6 minutes; P<0.001), operative blood loss (1070.2 vs 414.9 m L; P<0.001) and intraoperative blood transfusion (1.4 vs 0.2 units; P<0.001). Variations between the two groups in the frequency of complications were found to be statistically insignificant. However, the difference between the two groups in the overall morbidity of patients (47.6% vs 26.1%; P=0.009) and the length of their hospital stay (11.8 vs 7.8 days; P<0.001) were significant.CONCLUSION: A selective approach applied to the surgical management of periampullary cancer patients is a step in the right direction. | Omar J Shah Irfan Robbani Parveen Shah Sadaf A Bangri Irfan J Khan Mohammad Y Bhat Manmohan Singh | 2014 | Hepatobiliary & Pancreatic Diseases International2014,13,6: | 3 |
| 3 | Moving boundary shallow water flow above parabolic bottom topography显示文摘 | Joe Sampson Alan Easton Singh Manmohan | 2006 | ANZIAM Journal2006,47,2005: | 1 |
| 4 | Margaret Atwood' s Oryx and Crake : An Ecocritical Approach 显示文摘 | Bhalla Ambika Jap Preet Kaur Bhangu & Manmohan Singh | 2014 | International Journal of Research2014,10,1: | 1 |
| 5 | Sintered porous cermets based on TiB2-TiC-Mo2C显示文摘 | Manmohan Singh Rai K N | 2001 | Materials Chemistry and Physics2001,67,13: | 1 |
| 6 | Velocity of Pledged Collater-al Analysis and Implications显示文摘 | Singh Manmohan | | 0,,: | 1 |
| 7 | Money and Collateral显示文摘 | Singh Manmohan Peter Stella | | 0,,: | 1 |
| 8 | Migration, Production and Technology in Agriculture: a Case Study in the Indian Punjab 显示文摘 | A S Obera H K Manmohan Singh | 1982 | International Labor Review1982,,3: | 1 |
| 9 | Three-Dimensional Measurement Using a Single Image显示文摘 | William Thompson Manmohan Singh | 1996 | Optical Engineering1996,35,5: | 1 |
| 10 | Isolation, characterization, and EGFP expression in the buffalo ( Bubalus bubalis ) mammary gland epithelial cell line显示文摘 | Ramakant Kaushik Karn Pratap Singh Archana Kumari Manoj Kumar Singh Radhey Shyam Manik Prabhat Palta Suresh Kumar Singla Manmohan Singh Chauhan | 2013 | In Vitro Cellular & Developmental Biology - Animal2013,,1: | 1 |
| 11 | Controlled release of recombinant insulin-like growth factor from a novel formulation of polylactide-co-glycolide microparticles显示文摘 | Manmohan Singh Bret Shirley Kamal Bajwa Emil Samara Maninder Hora Derek O’Hagan | 2001 | Journal of Controlled Release2001,,1: | 1 |
| 12 | Physicochemical characterization of cationic gemini surfactants and their effect on reaction kinetics in ethylene glycol-water medium 显示文摘 | Deepti Tikariha Namrata Singh Manmohan L Satnami | 2012 | Colloids Surf A2012,411,10: | 1 |
| 13 | A cationic sub-micron emulsion (MF59/DOTAP) is an effective deli- very system for DNA vaccines显示文摘 | Gary Ott Manmohan Singh Jina Kazzaz | 2002 | Journal of Controlled Release2002,,79: | 1 |
| 14 | Andrographolide inhibits chikungunya virus infection by up-regulating host innate immune pathways显示文摘Objective: To investigate the therapeutic efficacy of andrographolide, a plant derived compound, against chikungunya virus(CHIKV) infection. Methods: Using flow cytometry and immunoblotting assay, in vitro viral protein expression was studied in THP-1 cells line. In Balb/c mouse neonates, viral RNA copy number was determined by real time PCR. Results:The results showed reduced CHIKV protein expression on andrographolide treatment in CHIKV-infected human peripheral blood mononuclear cells, Vero cells and THP-I cell line.In vivo, andrographolide treatment to CHIKV-infected neonates reduced viral RNA copy number. Further. andrographolide also increased cytotoxic T lymphocytes both in vitro and in vivo. Andrographolide also activated host innate immune pathways, viz., protein kinase R.phosphorylated eukaryotic initiation factor 2 α, retinoic acid inducible gene-Ⅰ and interferon regulatory factor 3/7, thereby increasing IFN-a secretion. CHIKV-induced nuclear factor κlight chain enhancer of activated B cells and tumor necrosis factor-a was also reduced on andrographolide treatment. Conclusion: Andrographolide inhibits CHIKV by suppressing viral protein expression and up-regulating host innate immunity and hence could be an effective therapeutic agent against CHIKV infection. | Swati Gupta Kamla Prasad Mishra Paban Kumar Dash Manmohan Parida Lilly Ganju Shashi Bala Singh | 2018 | Asian Pacific Journal of Tropical Medicine2018,11,3: | 1 |
| 15 | Uncertainty and sensitivity analysis of the basic reproduction number of a vaccinated epidemic model of influenza 显示文摘 | Md Samsuzzoha Manmohan Singh David Lucy | 2013 | Applied mathematical modelling2013,37,3: | 1 |
| 16 | Synthesis and reducing power assay of methyl semicarbazone derivatives显示文摘 | Manmohan Singhal Arindam Paul Hemendra P. Singh | 2011 | Journal of Saudi Chemical Society2011,,: | 1 |
| 17 | Measurement of radon and thoron progeny outdoors in Malout, India, using grab aerosol sampling and beta counting显示文摘 | Kulwant Singh Surinder Singh Rohit Mehra Manmohan Singh H.S. Sahota Z. Papp | 2005 | Radiation Measurements2005,,1: | 1 |
| 18 | Hearing improvement following gamma knife radiosurgery for an intra-canalicular vestibular schwannoma显示文摘 | Amol Raheja Manish Sharma Manmohan Singh Deepak Aggarwal Shashank Kale Bhawani Sharma | 2013 | Neurology India2013,,6: | 1 |
| 19 | Identification of QTLs for Yield and Associated Traits in F_(2) Population of Rice显示文摘Identification of quantitative trait loci(QTLs)controlling yield and yield-related traits in rice was performed in the F_(2) mapping population derived from parental rice genotypes DHMAS and K343.A total of 30 QTLs governing nine different traits were identified using the composite interval mapping(CIM)method.Four QTLs were mapped for number of tillers per plant on chromosomes 1(2 QTLs),2 and 3;three QTLs for panicle number per plant on chromosomes 1(2 QTLs)and 3;four QTLs for plant height on chromosomes 2,4,5 and 6;one QTL for spikelet density on chromosome 5;four QTLs for spikelet fertility percentage(SFP)on chromosomes 2,3 and 5(2 QTLs);two QTLs for grain length on chromosomes 1 and 8;three QTLs for grain width on chromosomes1,3 and 8;three QTLs for 1000-grain weight(TGW)on chromosomes 1,4 and 8 and six QTLs for yield per plant(YPP)on chromosomes 2(3 QTLs),4,6 and 8.Most of the QTLs were detected on chromosome 2,so further studies on chromosome 2 could help unlock some new chapters of QTL for this cross of rice variety.Identified QTLs elucidating high phenotypic variance can be used for marker-assisted selection(MAS)breeding.Further,the exploitation of information regarding molecular markers tightly linked to QTLs governing these traits will facilitate future crop improvement strategies in rice. | Rohini Bhat Anil Kumar Singh Muntazir Mushtaq Romesh Kumar Salgotra Manmohan Sharma Basharat Ahmad Bhat Umer Basu Ibrahim Al-Ashkar Mohammad Anwar Hossain Akihiro Ueda Ayman El Sabagh | 2022 | Phyton-International Journal of Experimental Botany2022,91,11: | 0 |
| 20 | Pancreaticoduodenectomy:A study from India on the impact of evolution from a low to a high volume unit显示文摘AIM To analyse the impact of turning of our department from a low to a high volume provider of pancreaticoduodenectomy(PD) on surgical outcome.METHODS A retrospective collection of data was done for patients who underwent PD.According to the number of PDs undertaken per year,we categorized the volume into low volume(< 10 PDs/year),medium volume(10-24 PDs/year) and high volume(> 25 PDs/year) groups.RESULTS From 2002 to 2013,200 patients underwent PD.The annual number of PD increased from 4 in 2002 to 34 in 2013.The mean operative time,operative blood loss and need for intraoperative blood transfusion decreased considerably over the volume categories(P < 0.001,P < 0.001 and P < 0.001,respectively).Increased procedural volume was associated with a lower morbidity(P = 0.021) and shorter length of hospital stay(P < 0.001).Similarly the rate of mortality dropped from 10% for the low volume group to 2.2% for the medium volume group and 0.0% for the high volume group(P = 0.007).CONCLUSION The transformation from a low volume to a high volume provider of PD resulted in most favourable outcomes favouring the continued centralization of this high risk procedure. | Omar J Shah Manmohan Singh Mohammad R Lattoo Sadaf A Bangri | 2016 | World Journal of Gastrointestinal Surgery2016,8,8: | 0 |