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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | 《日本慢性耳鸣诊治临床实践指南》摘译显示文摘人群中耳鸣的患病率为10%~15%,其中存在临床问题的占20%。在日本,出现耳鸣并深感痛苦的患者大约有300万,一些难治性耳鸣的治疗效果不尽如人意。本指南适用于慢性耳鸣患者,旨在规范耳鸣的循证诊断和治疗,提高耳鸣患者的生活质量。近年来发现,认知行为疗法和声治疗是减少耳鸣患者痛苦的有效方法。在日本医疗机构的医生都有权决定是否进行不同的治疗,并且还确定了治疗耳鸣的设施区域之间的差异。做到耳鸣评价标准化,以及为慢性耳鸣制定循证治疗指南。耳鸣临床实践指南的循证标准化是提高日本耳鸣医学检查水平的重要课题,该指南由小组委员会成员制定,由日本听力学会编辑,并由日本耳鼻喉科学会授权。 | 夏红艳(摘译) 赵立东(摘译) 王秋菊(审校) Ogawa K Sato H Takahashi M | 2021 | 听力学及言语疾病杂志2021，29，1： | 8 |
| 4 | Aclivation of the precursor of gelatinase A/72 KD type Ⅳ colleguenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase and with lymph node metastasis显示文摘 | Tokurku M Sato H Murakami S | 1995 | Int J Cancer1995，，： | 5 |
| 5 | Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts显示文摘 | T Komori H Yagi S Nomura A Yamaguchi K Sasaki K Deguchi Y Shimizu R.T Bronson Y.-H Gao M Inada M Sato R Okamoto Y Kitamura S Yoshiki T Kishimoto | 1997 | Cell1997，，5： | 2 |
| 6 | Drug combinations with amoxycillin reduce selection of clarithromycin resistance during Helicobacter pylori eradication therapy显示文摘 | K Murakami T Fujioka T Okimoto R Sato M Kodama M Nasu | 2002 | International Journal of Antimicrobial Agents2002，，1： | 2 |
| 7 | 采用增强的中间层改进高功率发动机用铝-硅-锡多层轴瓦显示文摘最近高功率车用发动机的紧凑和轻型结构的趋势已迫使对轴瓦的疲劳强度、抗咬合性和顺应性提出了更高的要求。为了满足这些要求,作者分析了铝-硅-锡多层轴瓦的每层性能,并研究了其对轴瓦性能的影响。根据研究结果,对轴承合金和中间粘接层作了改进。因而,这种新改进的轴瓦能提供比传统轴瓦更高的疲劳强度。这样就有可能使它成为当前用于苛刻条件下的发动机的一种轴瓦。 | Sato Y Mizuno Y Sakamoto M 王耀清 | 1996 | 国外内燃机1996，28，2： | 2 |
| 8 | 尿酸是正常高值血压发展为高血压的一个重要危险标志物显示文摘正常高值血压常发展为高血压,是一个与心血管病和脑卒中高死亡率和高发病率相关的事件。然而,正常高值血压发展成高血压的危险因素仍不清楚。研究者采用年龄(52.1±11.0)岁日本成年高血压患者3584例(2081例为男性)的资料进行前瞻性群体研究,研究对象在2004年被发现处于正常高值血压阶段,并在2009年重新进行检查。 | 黄洁 叶鹏 Kuwabara M Hisatome I Niwa K Hara S Roncal-Jimenez CA Bjornstad P Nakagawa T Andres-Hernando A Sato Y Jensen T Garcia G Rodriguez-Iturbe B Ohno M Lanaspa MA Johnson RJ | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 9 | Effect of piracetam on cerebral blood flow and somatosensory evoked potential during normotension and hypotensive ischemia in cats显示文摘 | Sato M Heiss WD | 1985 | Arznein-Forsch/Drug Res1985，35，： | 2 |
| 10 | Treatment of Wastewater from Phenolic Resin Process by Pervaporation显示文摘 | M Kondo H Sato | 1994 | Desalination1994，98，： | 2 |
| 11 | Temporal profile of stem cell division,migration,and differentiation from subventricular zone to olfactory bulb after transient forebrain ischemia in gerbils显示文摘 | Iwai M Sato K Kamada H | 2003 | J Cereb Blood Flow Metab2003，23，： | 2 |
| 12 | Mechanically Induced Avoidance Response of Chloroplasts in Fern Protonemal Cells 显示文摘 | SATO Y KADOTA A WADA M | 1999 | Plant Physiol1999，121，： | 1 |
| 13 | Diacylglycerol production in a packed bed bioreactor显示文摘 | WATANABE T SUGIURA M SATO M | 2005 | Process Biochem2005，40，2： | 1 |
| 14 | Aldosterone breakthrough during angiotensin Ⅱ receptor antagonist therapy in stroke-prone spontaneously hypertensive rats 显示文摘 | Naruse M Tanabe A Sato A | 2002 | Hypertension2002，40，1： | 1 |
| 15 | Rhodium(I)-or ruthenium(II)-catalyzed direct coupling of vinyl ketones with aldehydes and the subsequent reduction to give aldol derivatives anti-selectively显示文摘 | Sato S Matsuda L Shibata M | 1989 | J Organomet Chem1989，377，： | 1 |
| 16 | TAGE ( toxic AGEs) theory in diabetic complications显示文摘 | Sato T Iwaki M Shimogaito N | 2006 | Curr Mol Med2006，6，3： | 1 |
| 17 | Preparation and properties of salt-induced gel of whey protein显示文摘 | NAKAMURA M SATO K KOIZUMI S | 1995 | Journal of Japanese Society of Food Science and Technology1995，42，1： | 1 |
| 18 | Growth factor-induced phosphorylation of sterol regulatory element-bind ing proteins inhibits sumoylation, thereby stimulating the ex pression of their target genes,low density lipoprotein uptake, and lipid synthesis显示文摘 | Arito M Horiba T Hachimura S Inoue J Sato R | 2008 | J Biol Chem2008，283，15： | 1 |
| 19 | Tissue specific induction of metallothionein synthesis by tumor necrosis factor-α显示文摘 | Sasaki M Hoio H | 1992 | Res Comm Chem Path Pharmacol1992，72，： | 1 |
| 20 | Effects of L-carnitine supplementation on cardiac morbidity in hemodialyzed patients显示文摘 | Matsumoto Y Sato M Ohashi H | 2000 | Am J Nephrol2000，20，2： | 1 |
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