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| 1 | Effects of adacolumn selective leukocytapheresis on plasma cytokines during active disease in patients with active ulcerative colitis显示文摘瞄准:调查在临床的活动索引的 ulcerative (UC )( 蔡) 和 IL-1ra, IL-10, IL-6 和 IL-18 的传播层次之间的关系。方法:IL-1ra, IL-10, IL-6 和 IL-18 的血层次与活跃 UC 在 31 个病人被测量,吝啬的蔡是 11.1,从 5-25 ;并且是的 12 个健康个人控制。病人们与 Adacolumn 被给粒细胞和单核白血球 adsorptive 词首字母的脱落(GMA ) 。忍受 FcgammaR 并且补充受体的白细胞被吸附到列 leucocytapheresis 搬运人。每个病人能在 8 wk 上收到多达 11 个 GMA 会议。结果:我们发现了在蔡和 IL-10 之间的强壮的关联(r = 0.827, P <
0.001 ) , IL-6 (r = 0.785, P <
0.001 ) 并且 IL-18 (r = 0.791, P <
0.001 ) 。IL-1ra 没与蔡一起被相关。后面的 GMA 治疗, 31 个病人中的 24 个完成了宽恕,所有 4 cytokines 的层次掉在健康控制里到层次。进一步, IL-1ra 和 IL-10 的血层次在从遵守了搬运人的白细胞建议版本的 60 min 在列流出和流入增加了。 | Hiroyuki Hanai Takayuki Iida Masami Yamada Yoshihiko Sato Ken Takeuchi Tatsuo Tanaka Kenji Kondo Masataka Kikuyama Yasuhiko Maruyama Yasushi Iwaoka Akiko Nakamura Kazuhisa Hirayama Abby R Saniabadi Fumitoshi Watanabe | 2006 | World Journal of Gastroenterology2006，12，21： | 8 |
| 2 | 吸烟状况与急性缺血性脑卒中后功能结局的关系显示文摘吸烟是脑卒中的既定危险因素;然而,脑卒中前吸烟状态是否会影响急性缺血性脑卒中的临床预后尚不确定。该研究旨在阐明吸烟状态与急性缺血性脑卒中后功能预后的关系。研究者获取一项基于日本多中心医院的脑卒中登记资料,调查了2007年7-12月期间住院的10825例急性缺血性脑卒中患者,这些患者在脑卒中发作之前生活能够自理。吸烟状况分为从未吸烟者(不吸烟者),曾经吸烟者和现在吸烟者。临床结局包括3个月时功能转归不良(改良的Rankin量表评分≥2)和功能性依赖(改良的Rankin量表评分2~5)。 | 刘青(译) 刘莉(摘、审校) Matsuo R Ago T Kiyuna F Sato N Nakamura K Kuroda J Wakisaka Y Kitazono T | 2020 | 中华高血压杂志2020，28，2： | 4 |
| 3 | In vivo gastric mucosal histopathology using endocytoscopy显示文摘AIM:To study the ability of endocytoscopy to identify normal gastric mucosa and to exclude Helicobacter pylori(H.pylori) infection.METHODS:Endocytoscopic examination of the gastric corpus and antrum was performed in 70 consecutive patients.Target biopsy specimens were also obtained from the assessed region and multiple H.pylori tests were performed.The normal endocytoscopy patterns of the corpus and antrum were divided into the normal pit-dominant type(n-Pit) or the normal papilladominant type(n-Pap), respectively characterized as either regular pits with capillary networks or round, smooth papillary structures with spiral capillaries.On the other hand, normal mucosa was defined as mucosa not demonstrating histological abnormalities, including inflammation and atrophy.RESULTS:The sensitivity and specificity of n-Pit for normal mucosa in the gastric corpus were 94.4%and 97.1%,respectively,whereas those of n-Pap for normal mucosa in the antrum were 92.0%and 86.7%,respectively.The positive predictive values of n-Pit and n-Pap for H.pylori-negative tissue were 88.6%and 93.1%,respectively,and their negative predictive values for H.pylori-negative tissues were 42.9%and41.5%,respectively.The inter-observer agreement for determining n-Pit and n-Pap for normal mucosa were0.857 and 0.769,respectively,which is considered reliable.CONCLUSION:N-Pit and n-Pap,seen using EC,are considered useful predictors of normal mucosa and theabsence of H.pylori infection. | Hiroki Sato Haruhiro Inoue Haruo Ikeda Chiaki Sato Chainarong Phlanusittepha Bu'Hussain Hayee Esperanza Grace R Santi Yasutoshi Kobayashi Shin-ei Kudo | 2015 | World Journal of Gastroenterology2015，21，16： | 3 |
| 4 | Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts显示文摘 | T Komori H Yagi S Nomura A Yamaguchi K Sasaki K Deguchi Y Shimizu R.T Bronson Y.-H Gao M Inada M Sato R Okamoto Y Kitamura S Yoshiki T Kishimoto | 1997 | Cell1997，，5： | 2 |
| 5 | Drug combinations with amoxycillin reduce selection of clarithromycin resistance during Helicobacter pylori eradication therapy显示文摘 | K Murakami T Fujioka T Okimoto R Sato M Kodama M Nasu | 2002 | International Journal of Antimicrobial Agents2002，，1： | 2 |
| 6 | Ketonization of carboxylic acids over CeO2-based composite oxides显示文摘 | Nagashima O Sato S Takahashi R | 2005 | Journal of Molecular Catalysis A: Chemical2005，227，12： | 1 |
| 7 | Visible-light sensitization of TiO2 photocatalysts by wet-method n doping显示文摘 | Sato S Nakamura R Abe S | 2005 | Appl Catal A2005，284，： | 1 |
| 8 | Growth factor-induced phosphorylation of sterol regulatory element-bind ing proteins inhibits sumoylation, thereby stimulating the ex pression of their target genes,low density lipoprotein uptake, and lipid synthesis显示文摘 | Arito M Horiba T Hachimura S Inoue J Sato R | 2008 | J Biol Chem2008，283，15： | 1 |
| 9 | Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA显示文摘 | MARCHESI J R SATO T A WEIGHTMAN J | 1998 | Applied and Environmental Microbiology1998，64，： | 1 |
| 10 | The carbon monoxide-binding pigment of liver microsomes 显示文摘 | OMURA T SATO R | 1964 | J Biol Chem1964，239，： | 1 |
| 11 | Visible-light sensitization of TiO2 photocatalysts by wet-method N doping 显示文摘 | Sato S Nakamura R Abe S | 2005 | Appl Catal A2005，284，： | 1 |
| 12 | Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells显示文摘 | Sato T Haimovici R Kao R | 2002 | Diabetes2002，51，： | 1 |
| 13 | Cervical spondylotic myelopathy associated with kyphosis or sagittal sigmoid alignment :outcome after anterior or posterior decompression 显示文摘 | Uchida K Nakajima H Sato R | 2009 | J Neurosurg Spine2009，11，5： | 1 |
| 14 | Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and inva- sion of pancreatic ductal adenocarcinoma显示文摘 | Sato N Parker A R Fukushima N | 2005 | Oncogene2005，24，5： | 1 |
| 15 | A Green Route to Adipic Acid:Direct Oxidation of Cyclohexenes with 30 Percent Hydrogen Peroxide显示文摘 | Sato K Aoki M Noyori R | 1998 | Science1998，281，： | 1 |
| 16 | Tumor angiogenesis, hepatocyte growth factor, and c-Met expression in endometrial carcinoma 显示文摘 | Wagatsuma S Konno R Sato S | 1998 | Cancer1998，82，3： | 1 |
| 17 | Seroprevalence of Helicobacter pylori infection in patients with connective tissue diseases显示文摘 | Showji Y Nozawa R Sato K | 1996 | Microbiol Immunol1996，40，7： | 1 |
| 18 | Increased serum levels of vascular endothelial growth factor in patients with renal cell carcinoma显示文摘 | Sato K Tsuchiya N Sasaki R | 1999 | Jpn J Cancer Res1999，90，8： | 1 |
| 19 | Study of Clara cell 16, KL-6, and surfactant protein-D in serum as disease markers in pulmonary sarcoidosis 显示文摘 | Janssen R Sato H Grutters J | 2003 | Chest2003，124，： | 1 |
| 20 | The mammalian Mediator complex and its role in transcriptional regula- tion显示文摘 | CONAWAY R C SATO S TOMOMORI SATO C | 2005 | Trends Biochem2005，30，5： | 1 |
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