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| 1 | Coronary thrombus in patients undergoing primary PCI for STEMI:Prognostic significance and management显示文摘Acute ST-elevation myocardial infarction(STEMI) usually results from coronary atherosclerotic plaque disruption with superimposed thrombus formation. Detection of coronary thrombi is a poor prognostic indicator,which is mostly proportional to their size and composition. Particularly,intracoronary thrombi impair both epicardial blood flow and myocardial perfusion,by occluding major coronary arteries and causing distal embolization,respectively. Thus,although primary percutaneous coronary intervention is the preferred treatement strategy in STEMI setting,the associated use of adjunctive antithrombotic drugs and/or percutaneous thrombectomy is crucial to optimize therapy of STEMI patients,by improving either angiographical and clinical outcomes. This review article will focus on the prognostic significance of intracoronary thrombi and on current antithrombotic pharmacological and interventional strategies used inthe setting of STEMI to manage thrombotic lesions. | Sabine Vecchio Elisabetta Varani Tania Chechi Marco Balducelli Giuseppe Vecchi Matteo Aquilina Giulia Ricci Lucchi Alessro Dal Monte Massimo Margheri | 2014 | World Journal of Cardiology2014，6，6： | 18 |
| 2 | Water-immersion Technique During Standard Upper Endoscopy May Be Useful to Drive the Biopsy Sampling of Duodenal Mucosa in Children With Celiac Disease显示文摘 | Giovanni Cammarota Alessia Cazzato Orazio Genovese Adriano Pantanella Gianluca Ianiro Valentina Giorgio Massimo Montalto Fabio M Vecchio Luigi M Larocca Giovanni Gasbarrini Carlo Fundarò | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，4： | 2 |
| 3 | Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease显示文摘 | Luca Miele Venanzio Valenza Giuseppe La Torre Massimo Montalto Giovanni Cammarota Riccardo Ricci Roberta Mascianà Alessandra Forgione Maria L. Gabrieli Germano Perotti Fabio M. Vecchio Gianlodovico Rapaccini Giovanni Gasbarrini Chris P. Day Antonio Grieco | 2009 | Hepatology2009，，6： | 2 |
| 4 | Reducing Power Consumption in Wireless Sensor Networks Using a Novel Approach to Data Aggregation显示文摘 | Silvio Croce Francesco Marcelloni Massimo Vecchio | 2008 | The Computer Journal2008，51，2： | 1 |
| 5 | Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia显示文摘 | Giovanni Cammarota Giuseppe A. Pirozzi Antonio Martino Giuseppe Zuccalà Rossella Cianci Lucio Cuoco Veronica Ojetti Matteo Landriscina Massimo Montalto Fabio M. Vecchio Giovanni Gasbarrini Antonio Gasbarrini | 2004 | Gastrointestinal Endoscopy2004，，2： | 1 |
| 6 | Solving the node localization problem in WSNs by a two-objec- tive evolutionary algorithm and local descent 显示文摘 | Massimo Vecchio Roberto Lopez-Valcarce Francesco Marcello- hi | 2010 | IEEE Signal Processing Mag2010，22，4： | 1 |
| 7 | Direct visualization of intestinal villi by high-resolution magnifying upper endoscopy: a validation study显示文摘 | Giovanni Cammarota Antonio Martino Giuseppe A. Pirozzi Rossella Cianci Filippo Cremonini Giuseppe Zuccalà Lucio Cuoco Veronica Ojetti Massimo Montalto Fabio M. Vecchio Antonio Gasbarrini Giovanni Gasbarrini | 2004 | Gastrointestinal Endoscopy2004，，5： | 1 |
| 8 | Prognosis of Asymptomatic Patients With Hypertrophic Cardiomyopathy and Nonsustained Ventricular Tachycardia显示文摘 | Paolo Spirito Claudio Rapezzi Camillo Autore Paolo Bruzzi Pietro Bellone Paolo Ortolani Pietro V. Fragola Franco Chiarella Massimo Zoni-Berisso Angelo Branzi Dario Cannata Bruno Magnani Carlo Vecchio | 1994 | Circulation1994，，6： | 1 |
| 9 | Reverse time-dependent effect of alphafetoprotein and disease control on survival of patients with Barcelona Clinic Liver Cancer stage C hepatocellular carcinoma显示文摘AIM To characterize the survival of cirrhotic patients with Barcelona Clinic Liver Cancer(BCLC) stage C hepatocellular carcinoma(HCC) and to ascertain the factors predicting the achievement of disease control(DC).METHODS The cirrhotic patients with BCLC stage C HCC evaluated by the Hepatocatt multidisciplinary group were subjected to the investigation. Demographic, clinical and tumor features, along with the best tumor response and overall survival were recorded. RESULTS One hundred and ten BCLC stage C patients were included in the analysis; the median overall survival was 13.4 mo(95%CI: 10.6-17.0). Only alphafetoprotein(AFP) serum level > 200 ng/m L and DC could independently predict survival but in a time dependent manner, the former was significantly associated with increased risk of mortality within the first 6 mo of follow-up(HR = 5.073, 95%CI: 2.159-11.916, P = 0.0002), whereas the latter showed a protective effect against death after one year(HR = 0.110, 95%CI: 0.038-0.314, P < 0.0001). Only patients showing microvascular invasion and/or extrahepatic spread recorded lower chances of achieving DC(OR = 0.263, 95%CI: 0.111-0.622, P = 0.002).CONCLUSION The BCLC stage C HCC includes a wide heterogeneous group of cirrhotic patients suitable for potentially curative treatments. The reverse and time dependent effect of AFP serum level and DC on patients' survival confers them as useful predictive tools for treatment management and clinical decisions. | Francesca Romana Ponziani Irene Spinelli Emanuele Rinninella Lucia Cerrito Antonio Saviano Alfonso Wolfango Avolio Michele Basso Luca Miele Laura Riccardi Maria Assunta Zocco Brigida Eleonora Annicchiarico Matteo Garcovich Marco Biolato Giuseppe Marrone Anna Maria De Gaetano Roberto Iezzi Felice Giuliante Fabio Maria Vecchio Salvatore Agnes Giovanni Addolorato Massimo Siciliano Gian Lodovico Rapaccini Antonio Grieco Antonio Gasbarrini Maurizio Pompili | 2017 | World Journal of Hepatology2017，9，36： | 1 |
| 10 | Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia显示文摘 | Giovanni Cammarota Giuseppe A. Pirozzi Antonio Martino Giuseppe Zuccalà Rossella Cianci Lucio Cuoco Veronica Ojetti Matteo Landriscina Massimo Montalto Fabio M. Vecchio Giovanni Gasbarrini Antonio Gasbarrini | 2004 | Gastrointestinal Endoscopy2004，，2： | 1 |
| 11 | Direct visualization of intestinal villi by high-resolution magnifying upper endoscopy: a validation study显示文摘 | Giovanni Cammarota Antonio Martino Giuseppe A. Pirozzi Rossella Cianci Filippo Cremonini Giuseppe Zuccalà Lucio Cuoco Veronica Ojetti Massimo Montalto Fabio M. Vecchio Antonio Gasbarrini Giovanni Gasbarrini | 2004 | Gastrointestinal Endoscopy2004，，5： | 1 |
| 12 | Safety of etanercept in patients with psoriasis and hepatitis C virus assessed by liver histopathology: Preliminary data显示文摘 | Andrea Paradisi Giacomo Caldarola Rodolfo Capizzi Massimo Siciliano Eleonora Annichiarico Fabio Maria Vecchio Pier Luigi Amerio Clara De Simone | 2009 | Journal of the American Academy of Dermatology2009，，6： | 1 |
| 13 | Safety of etanercept in patients with psoriasis and hepatitis C virus assessed by liver histopathology: Preliminary data显示文摘 | Andrea Paradisi Giacomo Caldarola Rodolfo Capizzi Massimo Siciliano Eleonora Annichiarico Fabio Maria Vecchio Pier Luigi Amerio Clara De Simone | 2009 | Journal of the American Academy of Dermatology2009，，6： | 1 |
| 14 | Enabling Energy-Efficient and Lossy-Aware Data Compression in Wireless Sensor Networks by Multi-Objective Evolutionary Optimization显示文摘 | FRANCESCO MARCELLONI MASSIMO VECCHIO | 2010 | Information Sciences2010，180，10： | 1 |
| 15 | Water-immersion Technique During Standard Upper Endoscopy May Be Useful to Drive the Biopsy Sampling of Duodenal Mucosa in Children With Celiac Disease显示文摘 | Giovanni Cammarota Alessia Cazzato Orazio Genovese Adriano Pantanella Gianluca Ianiro Valentina Giorgio Massimo Montalto Fabio M Vecchio Luigi M Larocca Giovanni Gasbarrini Carlo Fundarò | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，4： | 1 |
| 16 | Genomic and functional evaluation of TNFSF14 in multiple sclerosis susceptibility显示文摘Among multiple sclerosis(MS)susceptibility genes,the strongest non-human leukocyte antigen(HLA)signal in the Italian population maps to the TNFSF14 gene encoding LIGHT,a glycoprotein involved in dendritic cell(DC)maturation.Through fine-mapping in a large Italian dataset(4,198 patients with MS and3,903 controls),we show that the TNFSF14 intronic SNP rs1077667 is the primarily MS-associated variant in the region.Expression quantitative trait locus(e QTL)analysis indicates that the MS risk allele is significantly associated with reduced TNFSF14 messenger RNA levels in blood cells,which is consistent with the allelic imbalance in RNA-Seq reads(P<0.0001).The MS risk allele is associated with reduced levels of TNFSF14 gene expression(P<0.01)in blood cells from 84 Italian patients with MS and 80 healthy controls(HCs).Interestingly,patients with MS are lower expressors of TNFSF14 compared to HC(P<0.007).Individuals homozygous for the MS risk allele display an increased percentage of LIGHT-positive peripheral blood myeloid DCs(CD11 c+,P=0.035)in 37 HCs,as well as in in vitro monocyte-derived DCs from 22 HCs(P=0.04).Our findings suggest that the intronic variant rs1077667 alters the expression of TNFSF14 in immune cells,which may play a role in MS pathogenesis. | Miriam Zuccala Nadia Barizzone Elena Boggio Luca Gigliotti Melissa Sorosina Chiara Basagni Roberta Bordoni Ferdinando Clarelli Santosh Anand Eleonora Mangano Domizia Vecchio Elena Corsetti Serena Martire Simona Perga Daniela Ferrante Alberto Gajofatto Andrei Ivashynka Claudio Solaro Roberto Cantello Vittorio Martinelli Giancarlo Comi Massimo Filippi Federica Esposito Maurizio Leone Gianluca De Beilis Umberto Dianzani Filippo Martinelli-Boneschi Sandra D’Alfonso | 2021 | Journal of Genetics and Genomics2021，48，6： | 0 |
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