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| 1 | Effectiveness of Sodium Chloride --Based Anti--Icing Filler in Asphalt Mixture显示文摘 | Felice Giuliani Filippo Merusi Giovanni Polacco Sara Filippi Massimo Paci | 2012 | Con- struction and Building Materials2012，，： | 1 |
| 2 | Secondary progressive multiple sclerosis: current knowledge and future challenges显示文摘 | Marco Rovaris Christian Confavreux Roberto Furlan Ludwig Kappos Giancarlo Comi Massimo Filippi | 2006 | Lancet Neurology2006，，4： | 1 |
| 3 | Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis显示文摘 | David Miller Frederik Barkhof Xavier Montalban Alan Thompson Massimo Filippi | 2005 | Lancet Neurology2005，，5： | 1 |
| 4 | Infantile Hemangiomas, Retinopathy of Prematurity and Cancer: A Common Pathogenetic Role of the β‐Adrenergic System显示文摘 | Luca Filippi Massimo Dal Monte Giovanni Casini Marta Daniotti Federica Sereni Paola Bagnoli | 2015 | Med. Res. Rev2015，，： | 1 |
| 5 | Assessment of posterior fossa damage in MS using MRI显示文摘 | Tarek A Yousry Robert I Grossman Massimo Filippi | 2000 | Journal of the Neurological Sciences2000，，： | 1 |
| 6 | Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives显示文摘Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons.Amyotrophic lateral sclerosis is the most common and aggressive form of motor neuron disease with no effective treatment so far.Unfortunately,diagnostic and prognostic biomarkers are lacking in clinical practice.Neurofilaments are fundamental structural components of the axons and neurofilament light chain and phosphorylated neurofilament heavy chain can be measured in both cerebrospinal fluid and serum.Neurofilament light chain and phosphorylated neurofilament heavy chain levels are elevated in amyotrophic lateral sclerosis,reflecting the extensive damage of motor neurons and axons.Hence,neurofilaments are now increasingly recognized as the most promising candidate biomarker in amyotrophic lateral sclerosis.The potential usefulness of neurofilaments regards various aspects,including diagnosis,prognosis,patient stratification in clinical trials and evaluation of treatment response.In this review paper,we review the body of literature about neurofilaments measurement in amyotrophic lateral sclerosis.We also discuss the open issues concerning the use of neurofilaments clinical practice,as no overall guideline exists to date;finally,we address the most recent evidence and future perspectives. | Yuri Matteo Falzone Tommaso Russo Teuta Domi Laura Pozzi Angelo Quattrini Massimo Filippi Nilo Riva | 2021 | Neural Regeneration Research2021，16，10： | 1 |
| 7 | Hepatic Resection for “BCLC Stage A” Hepatocellular Carcinoma. The Prognostic Role of Alpha-Fetoprotein显示文摘 | Roberto Santambrogio MD Enrico Opocher MD Mara Costa MD Matteo Barabino MD Massimo Zuin MD Emanuela Bertolini MD Francesca Filippi MD Savino Bruno MD | 2012 | Annals of Surgical Oncology2012，，2： | 1 |
| 8 | Effect of early interferon treatment on conversion todefinite multiple sclerosis:a randomised study显示文摘 | Giancarlo Comi Massimo Filippi Frederik Barkhof | 2001 | Lancet2001，357，： | 1 |
| 9 | Hepatocellular carcinoma in cirrhotic patients: prospective comparison of US, CT and MR imaging显示文摘 | Michele Martino Gianmaria Filippis Adriano Santis Daniel Geiger Maurizio Monte Concetta Valentina Lombardo Massimo Rossi Stefano Ginanni Corradini Gianluca Mennini Carlo Catalano | 2013 | European Radiology2013，，4： | 1 |
| 10 | Genomic and functional evaluation of TNFSF14 in multiple sclerosis susceptibility显示文摘Among multiple sclerosis(MS)susceptibility genes,the strongest non-human leukocyte antigen(HLA)signal in the Italian population maps to the TNFSF14 gene encoding LIGHT,a glycoprotein involved in dendritic cell(DC)maturation.Through fine-mapping in a large Italian dataset(4,198 patients with MS and3,903 controls),we show that the TNFSF14 intronic SNP rs1077667 is the primarily MS-associated variant in the region.Expression quantitative trait locus(e QTL)analysis indicates that the MS risk allele is significantly associated with reduced TNFSF14 messenger RNA levels in blood cells,which is consistent with the allelic imbalance in RNA-Seq reads(P<0.0001).The MS risk allele is associated with reduced levels of TNFSF14 gene expression(P<0.01)in blood cells from 84 Italian patients with MS and 80 healthy controls(HCs).Interestingly,patients with MS are lower expressors of TNFSF14 compared to HC(P<0.007).Individuals homozygous for the MS risk allele display an increased percentage of LIGHT-positive peripheral blood myeloid DCs(CD11 c+,P=0.035)in 37 HCs,as well as in in vitro monocyte-derived DCs from 22 HCs(P=0.04).Our findings suggest that the intronic variant rs1077667 alters the expression of TNFSF14 in immune cells,which may play a role in MS pathogenesis. | Miriam Zuccala Nadia Barizzone Elena Boggio Luca Gigliotti Melissa Sorosina Chiara Basagni Roberta Bordoni Ferdinando Clarelli Santosh Anand Eleonora Mangano Domizia Vecchio Elena Corsetti Serena Martire Simona Perga Daniela Ferrante Alberto Gajofatto Andrei Ivashynka Claudio Solaro Roberto Cantello Vittorio Martinelli Giancarlo Comi Massimo Filippi Federica Esposito Maurizio Leone Gianluca De Beilis Umberto Dianzani Filippo Martinelli-Boneschi Sandra D’Alfonso | 2021 | Journal of Genetics and Genomics2021，48，6： | 0 |
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