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| 1 | Trends of foodborne diseases in China: lessons from laboratory- based surveillance since 2011显示文摘Foodborne 疾病是世界范围的最重要的公共健康问题之一。中国在食物链的所有方面面对各种各样、崭新的挑战。从从 2013 ~ 2016 的基于实验室的 foodborne 疾病监视系统的数据,以及不同区域和年龄,能在与多样的特征检测的病原体的模式与差别一起被发现。Vibrio parahaemolyticus 是在中国的传染腹泻的领先的原因,特别在在沿海的区域的成年人之中。沙门氏菌是为实质的社会经济的负担负责的严肃、广泛地分布式的病原体。Shigella 主要在 5 年下面在孩子之中与开发更少的区域在西北中国和内陆省(河南省) 被识别。从从 2011 ~ 2016 报导系统的 foodborne 疾病爆发的数据证明有毒的动物和为大多数死亡负责的植物因素在在西南区域的遥远的区域是有毒的蘑菇(54.7%) 。引起了报导的大多数案例(42.3%) 的生物危险被归因于 V。parahaemolyticus, foodborne 爆发的领先的原因。在这评论,我们在中国总结最近的监视途径到 foodborne 疾病并且在发达国家把结果与那些作比较。 | Jikai Liu Li Bai Weiwei Li Haihong Han Ping Fu Xiaochen Ma Zhenwang Bi Xiaorong Yang Xiuli Zhang Shiqi Zhen Xiaoling Deng Xiumei Liu Yunchang Guo | 2018 | Frontiers of Medicine2018，12，1： | 55 |
| 2 | N_2O Emission from Paddy Field under Different Rice Planting Modes显示文摘Measurements of N2O emissions from conventional rice cultivation (CRC), CRC with straw mulching, system of rice intensification (SRI) and SRI with plastic film mulching were conducted through static chamber/gas-chromatography techniques. The results show that daily fluctuation of N2O emissions in jointing stage are much higher than in others. A type peak of N2O seasonal emission presented between jointing and bearing stages companying with high daily average temperature and low precipitation. Biomass and leaf stomatal conductance were observed. Total quantities of N2O emission were budgeted. The results showed that after jointing stage the average N2O emission flux of SRI with plastic film mulching increased significantly than CRC with straw mulching and SRI, the leaf stomatal conductance of those showed the same trend (p< 0.05 ). Yield and total quantity of N2O emission in CRC with straw mulching enhanced 13.7% and 10.7% compared with those of CRC, respectively. The total quantity of N2O emissions reduced 3.6% in SRI with plastic film mulching compared with CRC, however, the yield increase of that was not significant. | WANG Yuying ZHU Bo WANG Yanqiang GAO Meirong MA Xiumei | 2006 | Wuhan University Journal of Natural Sciences2006，11，4： | 7 |
| 3 | Hierarchically electrospraying a PLGA@chitosan sphere-in-sphere composite microsphere for multi-drug-controlled release显示文摘Sequential administration and controlled release of different drugs are of vital importance for regulating cellular behaviors and tissue regeneration,which usually demands appropriate carriers like microspheres(MS)to control drugs releases.Electrospray has been proven an effective technique to prepare MS with uniform particle size and high drug-loading rate.In this study,we applied electrospray to simply and hierarchically fabricate sphere-in-sphere composite microspheres,with smaller poly(lactic-co-glycolic acid)MS(~8-10 lm in diameter)embedded in a larger chitosan MS(~250-300 lm in diameter).The scanning electron microscopy images revealed highly uniform MS that can be accurately controlled by adjusting the nozzle diameter or voltage.Two kinds of model drugs,bovine serum albumin and chlorhexidine acetate,were encapsulated in the microspheres.The fluorescence-labeled rhodamine-fluoresceine isothiocyanate(Rho-FITC)and ultraviolet(UV)spectrophotometry results suggested that loaded drugs got excellent distribution in microspheres,as well as sustained,slow release in vitro.In addition,far-UV circular dichroism and matrixassisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF-MS)results indicated original secondary structure and molecular weight of drugs after electrospraying.Generally speaking,our research proposed a modified hierarchically electrospraying technique to prepare sphere-in-sphere composite MS with two different drugs loaded,which could be applied in sequential,multi-modality therapy. | Zhu Liu Weilong Ye Jingchuan Zheng Qindong Wang Guowu Ma Huiying Liu Xiumei Wang | 2020 | Regenerative Biomaterials2020，7，4： | 5 |
| 4 | Fargeted elimination of mutant mitochondria DNA in MELAS-iPSCs by mitoTALENs显示文摘 | Yi Yang Han Wu Xiangjin Kang Yanhui Liang Ting Lan Tianjie Li Tao Tan Jiangyun Peng Quanjun Zhang Geng An Yali Liu Qian Yu Zhenglai Ma Ying Lian Boon Seng Soh Qingfeng Chen Ping Liu Yaoyong Chen Xiaofang Sun Rong Li Xiumei Zhen Yang Yu Xiaoping Li Yong Fan | 2018 | Protein & Cell2018，9，3： | 4 |
| 5 | A novel mitochondrial tRNA gene mutation in a chinese family with dilated cardiomyopathy and sensorineural deafness显示文摘Objective: To determine whether a mutation of mitochondrial DNA induces familial dilated cardiomyopathy in Chinese families with cardiomyopathy,and analyzed the correlation between the genotype and phenotype. Methods: Affected members in three Chinese families of the familial dilated cardiomyopathy underwent clinical evaluation and DNA analysis. Polymerase chain reaction and direct DNA sequencing were used to screen for mitochondrial DNA mutation. The type of mtDNA variations and clinical situation were analysed on the patients with mitochondrial DNA mutation. Results: The mitochondrial A3434G mutation was identified in one of the three families,the 3434 th nucleotide A was replaced by G, which led to change of amino acid. No mutations were identified in the clinically unaffected members of the family and all members of the other two families. Conclusion: This study indicates that the mitochondrial A3434G mutation maybe related with familial dilated cardiomyopathy and deafness. | Xianghong Wu Xiumei Xie Guotian Ma Guoju Sun Xiaobin Chen | 2006 | Journal of Nanjing Medical University2006，20，5： | 3 |
| 6 | Development of an antimicrobial peptide-loaded mineralized collagen bone scaffold for infective bone defect repair显示文摘The repair of infective bone defects is a great challenge in clinical work.It is of vital importance to develop a kind of bone scaffold with good osteogenic properties and long-term antibacterial activity for local anti-infection and bone regeneration.A porous mineralized collagen(MC)scaffold containing poly(D,L-lactide-co-glycolic acid)(PLGA)microspheres loaded with two antibacterial synthetic peptides,Pac-525 or KSL-W was developed and characterized via scanning electron microscopy(SEM),porosity measurement,swelling and mechanical tests.The results showed that the MC scaffold embedded with smooth and compact PLGA microspheres had a positive effect on cell growth and also had antibacterial properties.Through toxicity analysis,cell morphology and proliferation analysis and alkaline phosphatase evaluation,the antibacterial scaffolds showed excellent biocompatibility and osteogenic activity.The antibacterial property evaluated with Staphylococcus aureus and Escherichia coli suggested that the sustained release of Pac-525 or KSL-W from the scaffolds could inhibit the bacterial growth aforementioned in the long term.Our results suggest that the antimicrobial peptides-loaded MC bone scaffold has good antibacterial and osteogenic activities,thus providing a great promise for the treatment of infective bone defects. | Yuzhu He Yahui Jin Xiaoxia Ying Qiong Wu Shenglian Yao Yuanyuan Li Huiying Liu Guowu Ma Xiumei Wang | 2020 | Regenerative Biomaterials2020，7，5： | 3 |
| 7 | Synthesis and crystal structure of hydroquinone-β-cyclo-dextrin complex显示文摘The title inclusion complex with the formula [(C42H70O35)2 · (C6O2H6)3 · (H2O)21.2(CH3OH)2] has been crystallized and characterized by single crystal X-ray analysis. The complex crystallizes in the triclinic system, space group P1, with a =1.5500 (1), b =1.5536(1), c = 1.8246(1) nm, α = 113.17(2), β = 99.12(2), γ=103.37(3)? V = 3.7739(4) nm3, Z = 1; Dc =1.343 g/cm3, μ = 0.124 mm-1, F(000) = 1594, R = 0.0795 and S = 0.9639. Two independent molecules of β-cyclodextrin (β-CD) form a 'head-to-head' dimer. The fairly important factor of the position and stability of the guest in the host cavity is the solvation of the polar group of the guest. | Shikun Ma Jinling Wang Aixiu Li Ming Yu Ming Sun Xiumei Su Fangming Miao | 2001 | Chinese Science Bulletin2001，46，5： | 3 |
| 8 | Comparison of diagnostic value of PET using 18- fluoro-2-deoxyglucose, CT and MR1 in detecting skull base invasion of nasopharyngeal carcinomas显示文摘客观我们用 18-fluoro-2-deoxyglucose ( FDG )比较了正电子排放断层摄影术(宠物),提高的计算断层摄影术( CT )和在检测颅骨的磁性的回声成像( MRI )基于鼻咽的癌( NPC )的侵略并且基于鼻咽的癌的侵略在决定颅骨的存在评估这三个方法的价值。方法提高的 CT, MRI 和 PET-CT 扫描的图象,表现在间隔 ≤
到 2007 年 2 月的从 2004 年 7 月的 57 个 NPC 病人上的 20 天,被选择并且考察。比较的端点是敏感,特性,精确性,积极预兆的价值(PPV ) 和提高的 CT, MRI 和 PET-CT 的否定预兆的价值(NPV ) ,基于为至少 6 个月的组织病理学说的调查结果或临床的成像后续。检测 NPC,提高的 CT 的敏感, MRI 和 PET-CT 的颅骨底侵略的结果是 68.18% , 84.09% , 97.67% 分别地;特性是 76.92% , 69.23% , 57.14% 分别地;精确性是 70.18% , 80.7% , 87.72% 分别地;PPV 是 90.9% , 90.24% , 87.5% 分别地;NPV 是 41.67% , 56.25% , 88.89% 分别地。结论 PET-CT 比 CT 在敏感有明显的优点(P <
0.05 ) 并且 MRI,比在精确性和 NPV 的二个方法好并且可能为在检测 NPC 病人的颅骨底侵略的新病人更珍贵。 | Xiumei Ma Ming Ye Taifu Liu Li Li Liyan Dai | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，8： | 3 |
| 9 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
| 10 | Evaluation and Analysis of the Effect of Lignin Amelioration on Loess Collapsibility显示文摘The road subgrade and road surface in collapsible loess area are prone to many engineering diseases such as uneven subgrade settlement,insufficient bearing capacity of soaked foundation,collapse and instability of sub-grade side slope due to the special properties of loess.As an environment-friendly,low-cost soil modifier with good adhesion and chelation properties,lignin has been considered to be used in highway subgrade construction.In order to explore the effect of lignin on loess,the compressive and collapsible properties of modified loess with different lignin contents were analyzed based on consolidation compression test.The improvement mechanism of lignin on loess collapsibility was studied by means of infiltration test and SEM test.The results show that lignin fibers can promote the agglomeration of loose particles and form a network structure in the soil particle pores,enhance the cementation strength between particles and soil skeleton,and reduce the permeability of loess.With the increase of lignin fiber content,the improvement degree of loess collaps ility shows a trend of first increasing and then decreasing.When the lignin fiber content is 2%,the effect is the best,and the improved loess ollapsi-bility is eliminated. | Xiumei Zhong Yuxin Liang Qian Wang Jinlian Ma Shouyun Liang Yan Wang Xiaowei Xu | 2022 | Journal of Renewable Materials2022，10，12： | 2 |
| 11 | In situ TEM revealing the effects of dislocations on lithium-ion migration in transition metal dichalcogenides显示文摘The two-dimensional (2D) structure of layered transition metal dichalcogenides (TMDs) provides unusual physical properties [1,2]and chemical reactivity [3,4], which can be influenced by defects such as dislocations [5,6]. For example, dislocations can act as nucleation sites for the onset of deformation when subjected to stress [7]. | Ruiwen Shao Chengkai Yang Chen Yang Shulin Chen Weikang Dong Bairong Li Xiumei Ma Jing Lu Lixin Dong Peng Gao Dapeng Yu | 2021 | Journal of Energy Chemistry2021，30，7： | 1 |
| 12 | The Design of Intelligent Lighting System in College Classroom显示文摘 | Jiang Luansheng Liu Chunxia Guo Xiumei Ma Chongxiao | 2012 | Energy Procedia2012，，： | 1 |
| 13 | Esterification of glycerol with acetic acid using double SO3 H - function- alized ionic liquids as recoverable catalysts 显示文摘 | Xiumei Liu Huiyuan Ma b Yue Wu | 2011 | Green Chem2011，13，： | 1 |
| 14 | MAS NMR, ESR and TPD studies of Mo/HZSM‐5 catalysts: evidence for the migration of molybdenum species into the zeolitic channels显示文摘 | Ding Ma Weiping Zhang Yuying Shu Xiumei Liu Yide Xu Xinhe Bao | 2000 | Catalysis Letters2000，，3： | 1 |
| 15 | Sinterability of Zirconia Top Coat of Investment Mold for Ti Alloy显示文摘In this paper. zirconia is used as top mold material for Ti investment casting. Top mold samples are made by proper mold building technology. The effect of different sintering temperature on chemical composition, microstructure and residual bending strength of the top mold sample is Studied. The volume and homogeneity of the air holes in the top mold are determined by sintering temperature. and finally determined the residual bending strength of the mold sample was determined. | Yuyong CHEN Xiumei QI Xuezhu MA Huiguang WANG and Jing TIAN School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 1 |
| 16 | Processing of Rhubarb and Determination of Five Free Anthraquinones in Raw Rhubarb and Stewed Rhubarb显示文摘[Objectives]To determine the content of five kinds of free anthraquinones in raw rhubarb and stewed rhubarb by HPLC,and compare their content difference,so as to reveal the change rule of material basis before and after processing of traditional Chinese medicine.[Methods]The content was determined by HPLC with Thermo BDS HYPERSII C18 column(4.6 mm×250 mm,5μm)as chromatographic column and methanol-0.1%phosphoric acid(85∶15)aqueous solution as mobile phase;the detection wavelength was 256 nm,the flow rate was 1.0 mL/min,the column temperature was 30℃,and the injection volume was 10μL.[Results]Aloe-emodin,rhein,emodin,chrysophanol and emodin methyl ether showed a good linear relationship in the linear range of 0.0207-0.414(R2=0.9999),0.1721-3.442(R2=0.9996),0.0203-0.406(R2=0.9999),0.148-2.96(R2=0.9998)and 0.164-3.28(R2=0.9993),respectively;the content of aloe-emodin decreased by about 8.26%,and rhein decreased by about 9.21%;the content of emodin increased by about 16.44%,chrysophanol increased by about 16.12%,and emodin methyl ether increased by about 20.01%,indicating that the processing technology had different effects on the components of rhubarb.[Conclusions]The content of five free anthraquinones in rhubarb was affected to different degrees after processing,and this method could be used as a quality control method for rhubarb and its different processed products. | Huazhen SU Xiumei MA Jiangcun WEI Yong CHEN Shaoyuan HUANG Liqing LIANG Meiyan QIU Fengxian ZHAO Qian HAN | 2020 | Medicinal Plant2020，11，5： | 1 |
| 17 | Purification and characterization of an alkaline protease from the marine aureobasidium pullulans for bioactive peptide production from different sources显示文摘 | Ma Chunling Ni Xiumei Chi Zhenming | 2007 | Marine bioteehnology2007，，9： | 1 |
| 18 | Comparative transcriptome and proteome analysis of lily clones inoculated with Fusarium oxysporum f. sp. lilii显示文摘Basal bulb rot is the major factor restricting the production of lily,caused by Fusarium oxysporum f.sp.lilii.To systematically analyze the transcriptomic and proteomic responses of lily clones to F.oxysporum,we constructed six RNA-seq libraries and four iTRAQ proteomic libraries using lily resistant and susceptible clones sampled at 0,24 and 48 h post-inoculation(hpi)with F.oxysporum respectively.137,715 unigenes were generated,of which 7,667 were differentially expressed.1,679 and 4,051 differentially expressed genes(DEGs)between resistant and susceptible clones were isolated from samples collected at 0 and 48 hpi.Four hundred and thirty three and 155 DEGs were identified in resistant clones sampled at 24 and 48 hpi separately while 550 and 799 DEGs were isolated in the susceptible clones sampled at 24 and 48 hpi respectively.The results of iTRAQ analysis revealed 7,482 proteins in resistant and susceptible clones.Data analysis of transcriptome and proteome indicated that 5,735 proteins corresponded to mRNAs.Three hundred and sixteen and 1,052 DEGs had corresponding DEPs.At 48 hpi,the resistant clones showed 155 DEGs and 108 corresponding DEPs,while the susceptible clones showed 799 DEGs and 316 corresponding DEPs.In general,these results enhance comprehension of the defense response of lily resistant clones to F.oxysporum infection and provide valuable sequence data for studying the resistance mechanism. | Yiping Zhang Xin Wang Chunlian Jin Feng Xu Xiumei Yang Yalian Jiang Lifang Zhang Lihua Wang Yan Su Lulin Ma Jihua Wang | 2022 | Ornamental Plant Research2022，2，1： | 1 |
| 19 | Solid-state MAS NMR studies on the hydrothermal stability of the zeolite catalysts for residual oil selective catalytic cracking显示文摘 | Jianqin Zhuang Ding Ma Gang Yang Zhimin Yan Xiumei Liu Xianchun Liu Xiuwen Han Xinhe Bao Peng Xie Zhongmin Liu | 2004 | Journal of Catalysis2004，，1： | 1 |
| 20 | Corrigendum to:Hierarchically electrospraying a PLGA@chitosan sphere-in-sphere composite microsphere for multi-drug-controlled release显示文摘 | Zhu Liu Weilong Ye Jingchuan Zheng Qindong Wang Guowu Ma Huiying Liu Xiumei Wang | 2020 | Regenerative Biomaterials2020，7，4： | 1 |
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