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| 1 | Maternal vitamin D level and vitamin D receptor gene polymorphism as a risk factor for congenital heart diseases in offspring;An Egyptian case-control study显示文摘Vitamin D&vitamin D receptor(VDR)signaling play a very crucial role in early embryonic heart development.We construct this case-control study to investigate the association between maternal serum vitamin D level&VDR gene Fok1 polymorphism and risk of congenital heart defects(CHD)in offspring.Fifty mothers who had term neonates with CHD were considered as cases.Fifty age-comparable healthy mothers who had neonates without CHD were contemplated as controls.Maternal serum 25 hydroxyvitamin D[25(OH)D]level was tested using ELISA.Maternal VDR gene Fok1 polymorphism was analyzed using PCR-based RFLP-assay.There was a significant decrease in maternal vitamin D level(P=0.002)and a significant increase in vitamin D deficient status(P=0.007)among cases when compared to controls.VDR gene Fok1 genotypes distribution frequency were in accordance with Hardy Weinberg equilibrium(HW)among controls.A significant increase in VDR gene Fok1 F/f&f/f genotypes and f allele were observed in cases compared to controls with estimated odds ratio(95%confidence interval)&P-value of 3(1e8)&P=0.006,11(1e97)&P=0.01 and 3(2e6)&P=0.001 respectively.There was a significant decrease in maternal vitamin D level in neonates with cyanotic CHD(P=0.000)compared to those with a cyanotic CHD while there was no significant difference in VDR Fok1 genotype(P=0.18)&allele(P=0.05)distribution between two groups.We concluded that maternal vitamin D deficiency and VDR gene Fok1 F/f,f/f genotype and f allele were associated with increased risk of CHD in offspring. | Wesam A.Mokhtar Amal Fawzy Reem M.Allam Rania M.Amer Mona S.Hamed | 2019 | Genes & Diseases2019,6,2: | 2 |
| 2 | Numerical analysis of an over-boarding operation for a subsea template显示文摘Subsea templates are normally transported to the installation site on the deck of a crane vessel.After being lifted off from the deck,the template is 1)over-boarded from the initial location to the target position by the side of the vessel;2)lowered through the splash zone;3)further lowered down to the seabed and 4)finally positioned and landed.All the mentioned phases should be evaluated.Usually,the splash zone crossing phase is taken as the critical phase and analyzed to define the installation weather criterion.The over-boarding phase has not been the focus of analysis due to a large involvement of human actions and little involvement of hydrodynamic effects.During offshore operations,the offshore manager may decide to decrease the defined installation weather criterion if the risk of the personnel safety on deck during over-boarding phase is considered high.Thus,it is of great need to quantify the operational criterion for such operation.The objective of this paper is to perform numerical analyses and define the allowable sea states for a safe over-boarding operation.The numerical analyses using time-domain simulations have been performed in various sea states.Tugger lines have been modelled to control the motions of the template during the operation.The pendulum motions of the subsea template are considered as the critical responses for the assessment of the allowable sea states. | Lin Li Adham M.Amer Xinying Zhu | 2021 | Journal of Ocean Engineering and Science2021,6,2: | 2 |
| 3 | Viral kinetic of HCV genotype‐4 during pegylated interferon alpha 2a: ribavirin therapy显示文摘 | M. F.Derbala N. Z.El Dweik S. R.Al Kaabi A. D.Al‐Marri F.Pasic A. B.Bener F. M.Shebl A. M.Amer M. T.Butt R.Yakoob A.John M.Al Mohanadi M. A.Al Khinji | 2008 | Journal of Viral Hepatitis2008,,8: | 1 |
| 4 | New Antenna Array Beamforming Techniques Based on Hybrid Convolution/Genetic Algorithm for 5G and Beyond Communications显示文摘Side lobe level reduction(SLL)of antenna arrays significantly enhances the signal-to-interference ratio and improves the quality of service(QOS)in recent and future wireless communication systems starting from 5G up to 7G.Furthermore,it improves the array gain and directivity,increasing the detection range and angular resolution of radar systems.This study proposes two highly efficient SLL reduction techniques.These techniques are based on the hybridization between either the single convolution or the double convolution algorithms and the genetic algorithm(GA)to develop the Conv/GA andDConv/GA,respectively.The convolution process determines the element’s excitations while the GA optimizes the element spacing.For M elements linear antenna array(LAA),the convolution of the excitation coefficients vector by itself provides a new vector of excitations of length N=(2M−1).This new vector is divided into three different sets of excitations including the odd excitations,even excitations,and middle excitations of lengths M,M−1,andM,respectively.When the same element spacing as the original LAA is used,it is noticed that the odd and even excitations provide a much lower SLL than that of the LAA but with amuch wider half-power beamwidth(HPBW).While the middle excitations give the same HPBWas the original LAA with a relatively higher SLL.Tomitigate the increased HPBWof the odd and even excitations,the element spacing is optimized using the GA.Thereby,the synthesized arrays have the same HPBW as the original LAA with a two-fold reduction in the SLL.Furthermore,for extreme SLL reduction,the DConv/GA is introduced.In this technique,the same procedure of the aforementioned Conv/GA technique is performed on the resultant even and odd excitation vectors.It provides a relatively wider HPBWthan the original LAA with about quad-fold reduction in the SLL. | Shimaa M.Amer Ashraf A.M.Khalaf Amr H.Hussein Salman A.Alqahtani Mostafa H.Dahshan Hossam M.Kassem | 2024 | Computer Modeling in Engineering & Sciences2024,138,3: | 0 |
| 5 | Dynamic Analysis of Splash-zone Crossing Operation for a Subsea Template显示文摘Subsea templates are steel structures used to support subsea well components.Normally,offshore crane vessels are employed to install them to the target location on the seabed.Crossing the splash-zone during the lowering of a subsea template is considered the most critical phase during the installation due to slamming loads and needs to be studied to provide the operational weather criterion during the planning phase.In this study,dynamic response analysis has been carried out to evaluate the allowable sea states for the plash-zone crossing phase of the subsea templates.The numerical model of the lifting system,including the crane vessel and the subsea template,is firstly built in the state-of-the-art numerical program SIMA-SIMO.Then,dynamic analysis with time-domain simulations is carried out for the lifting system under various sea states.The disturbed wave field due to the shielding effects from the installation vessel is considered when calculating the hydrodynamic forces on the template.Statistical modelling of the dynamic responses from different wave realizations is used to estimate the extreme responses of various sea states.The application of the generalized extreme value distribution and Gumbel distribution in fitting the extreme responses is discussed.Moreover,the influence of the shielding effects from the vessel,as well as the influence of the changing size of the suction anchor on the hydrodynamic responses and the allowable sea states are studied. | Adham M.Amer Lin Li Xinying Zhu | 2022 | Sustainable Marine Structures2022,4,2: | 0 |
| 6 | Proper Teleparallel Homothetic Vector Fields in General Cylindrically Symmetric Space-Times in Teleparallel Theory of Gravitation Using Diagonal Tetrads显示文摘In this paper we consider the most general form of non-static cylindrically symmetric space-times in order to study proper teleparallel homothetic vector fields using the direct integration technique and diagonal tetrads. This study also covers static cylindrically symmetric, Bianchi type I, non-static and static plane symmetric space-times as well. Here, we will only discuss the cases which do not fall in the category of static cylindrically symmetric, Bianchi type Ⅰ, non-static and static plane symmetric space-times. From the above study we show that very special classes of the above space-times yield 6, 7 and 8 teleparallel homothetic vector fields with non-zero torsion. | Ghulam Shabbir Masoom Ali Shahani M.Amer Qureshi F.M.Mahomed | 2017 | Communications in Theoretical Physics2017,67,11: | 0 |